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The map label for this gene is yisK [H]

Identifier: 169628014

GI number: 169628014

Start: 907106

End: 908032

Strand: Reverse

Name: yisK [H]

Synonym: MAB_0915c

Alternate gene names: 169628014

Gene position: 908032-907106 (Counterclockwise)

Preceding gene: 169628015

Following gene: 169628013

Centisome position: 17.92

GC content: 60.73

Gene sequence:

>927_bases
ATGAATTTGCGGATCGTCAGCTTCGCCGGTGCCGATCAATGGCAACCCGGCGTGCTCATCGACGATGACACCGTCGCTCC
CCTTGCGCCGATGCTCGCCCGTCACGACATCCAGGTGTCCTCGGCACGCGAGCTGATAGCACTGTTACCGCAGATCTCGC
CGTTGATCTCTGACGAACTCGCTGGTGGCTCTTTCGAACCGGTGCCGCTCGACTCCGTTGCGTTGGGGGCCCCGATTCCC
GAGCCCGGCCAGGTCATTGCTCTGGGCTTCAACTACCCGACACATTCAGACACCGATTCCCCGCTGCCGAAGATGGCGGA
CCCCGTCGTCTTCATGAAGTCGCCCACCAGCATTAGCGGCCCCCGTGACGCCGTCATCGCGCCGCGGACATCGCACGCAC
TCGATTACGAAATCGAAATTGCTGTCGTCATTGGGAAACCCGGATACCGCATCGAGCGCAGTCAGGCGATCAAGCACGTC
GCCGGATATATGCTCGCCAACGACATCACTGCCCGCGATGTTGCGCTACCGTTCGGCTTCGGCGGTTCGCCATTGCAGGC
GCAGGTTGTCCGCGGCAAGGGATACCCGACATTCTGCCCAACTGGCCCGTGGCTCTTTACCACCGGCTCAGATACGACGT
TTGAAACGTTCGACTTCGAACTTCGGATCAACGGCGAACTGCGGCAGAGCGGTTCAACGGTAGACATGACTCTCGGCTTC
GCCGAGGTTGTTGAAACAGTGAGTGCAACCATCGCCCTGCGCGCCGGGGACATCATCCTGACCGGAACGCCCGGCGGCTG
CGGATTCCAATTCGATCCTCCGCGCTACCTCCGACCGGGGGATGTGATCGAAGCTCATTCGGCCAAGTTGGGCAAAATGC
GGCTACCTGTCCACGACGAAAAACCCATCGAGAGCGCATCGAGGTAA

Upstream 100 bases:

>100_bases
CTCCGTGCCCGCTGTACAACACGTCGACGAACTACCGGCATGGTGACATAACCCGTTGTACAACTTGATATTTCACAACA
ATTGAAATGGGAAAGTACTG

Downstream 100 bases:

>100_bases
CGATGAAAATAACCTTCACCAATAGCGACGGCTACACGAAATCTCTTGACGCAGAAGAAGGCGTATCGCTCATGCATGTC
GCGGTTTCCCATGACGTGCC

Product: 2-hydroxyhepta-2,4-diene-1, 7-dioateisomerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MNLRIVSFAGADQWQPGVLIDDDTVAPLAPMLARHDIQVSSARELIALLPQISPLISDELAGGSFEPVPLDSVALGAPIP
EPGQVIALGFNYPTHSDTDSPLPKMADPVVFMKSPTSISGPRDAVIAPRTSHALDYEIEIAVVIGKPGYRIERSQAIKHV
AGYMLANDITARDVALPFGFGGSPLQAQVVRGKGYPTFCPTGPWLFTTGSDTTFETFDFELRINGELRQSGSTVDMTLGF
AEVVETVSATIALRAGDIILTGTPGGCGFQFDPPRYLRPGDVIEAHSAKLGKMRLPVHDEKPIESASR

Sequences:

>Translated_308_residues
MNLRIVSFAGADQWQPGVLIDDDTVAPLAPMLARHDIQVSSARELIALLPQISPLISDELAGGSFEPVPLDSVALGAPIP
EPGQVIALGFNYPTHSDTDSPLPKMADPVVFMKSPTSISGPRDAVIAPRTSHALDYEIEIAVVIGKPGYRIERSQAIKHV
AGYMLANDITARDVALPFGFGGSPLQAQVVRGKGYPTFCPTGPWLFTTGSDTTFETFDFELRINGELRQSGSTVDMTLGF
AEVVETVSATIALRAGDIILTGTPGGCGFQFDPPRYLRPGDVIEAHSAKLGKMRLPVHDEKPIESASR
>Mature_308_residues
MNLRIVSFAGADQWQPGVLIDDDTVAPLAPMLARHDIQVSSARELIALLPQISPLISDELAGGSFEPVPLDSVALGAPIP
EPGQVIALGFNYPTHSDTDSPLPKMADPVVFMKSPTSISGPRDAVIAPRTSHALDYEIEIAVVIGKPGYRIERSQAIKHV
AGYMLANDITARDVALPFGFGGSPLQAQVVRGKGYPTFCPTGPWLFTTGSDTTFETFDFELRINGELRQSGSTVDMTLGF
AEVVETVSATIALRAGDIILTGTPGGCGFQFDPPRYLRPGDVIEAHSAKLGKMRLPVHDEKPIESASR

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI156231349, Length=225, Percent_Identity=37.7777777777778, Blast_Score=156, Evalue=3e-38,
Organism=Homo sapiens, GI40786394, Length=225, Percent_Identity=37.3333333333333, Blast_Score=152, Evalue=3e-37,
Organism=Homo sapiens, GI215422413, Length=186, Percent_Identity=31.7204301075269, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI13654274, Length=220, Percent_Identity=31.3636363636364, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI66348062, Length=186, Percent_Identity=31.7204301075269, Blast_Score=93, Evalue=3e-19,
Organism=Escherichia coli, GI1787428, Length=190, Percent_Identity=31.5789473684211, Blast_Score=93, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17557057, Length=204, Percent_Identity=31.3725490196078, Blast_Score=84, Evalue=8e-17,
Organism=Saccharomyces cerevisiae, GI6324161, Length=234, Percent_Identity=26.9230769230769, Blast_Score=77, Evalue=4e-15,
Organism=Drosophila melanogaster, GI28572127, Length=224, Percent_Identity=37.0535714285714, Blast_Score=153, Evalue=2e-37,
Organism=Drosophila melanogaster, GI24663695, Length=237, Percent_Identity=32.4894514767932, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI28571789, Length=218, Percent_Identity=31.1926605504587, Blast_Score=103, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 32918; Mature: 32918

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLRIVSFAGADQWQPGVLIDDDTVAPLAPMLARHDIQVSSARELIALLPQISPLISDEL
CCEEEEEECCCCCCCCCEEECCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
AGGSFEPVPLDSVALGAPIPEPGQVIALGFNYPTHSDTDSPLPKMADPVVFMKSPTSISG
CCCCCCCCCCCCEECCCCCCCCCCEEEEEECCCCCCCCCCCCCHHCCCEEEEECCCCCCC
PRDAVIAPRTSHALDYEIEIAVVIGKPGYRIERSQAIKHVAGYMLANDITARDVALPFGF
CCCEEECCCCCCCEEEEEEEEEEECCCCCEECHHHHHHHHHHHHHHCCCCCCCEEEECCC
GGSPLQAQVVRGKGYPTFCPTGPWLFTTGSDTTFETFDFELRINGELRQSGSTVDMTLGF
CCCCCEEEEEECCCCCCCCCCCCEEEECCCCCEEEEEEEEEEECCHHHCCCCEEEEECCH
AEVVETVSATIALRAGDIILTGTPGGCGFQFDPPRYLRPGDVIEAHSAKLGKMRLPVHDE
HHHHHHHHHEEEEEECCEEEECCCCCCCCCCCCCCCCCCCCEEECCCCCCCEEECCCCCC
KPIESASR
CCCCCCCC
>Mature Secondary Structure
MNLRIVSFAGADQWQPGVLIDDDTVAPLAPMLARHDIQVSSARELIALLPQISPLISDEL
CCEEEEEECCCCCCCCCEEECCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
AGGSFEPVPLDSVALGAPIPEPGQVIALGFNYPTHSDTDSPLPKMADPVVFMKSPTSISG
CCCCCCCCCCCCEECCCCCCCCCCEEEEEECCCCCCCCCCCCCHHCCCEEEEECCCCCCC
PRDAVIAPRTSHALDYEIEIAVVIGKPGYRIERSQAIKHVAGYMLANDITARDVALPFGF
CCCEEECCCCCCCEEEEEEEEEEECCCCCEECHHHHHHHHHHHHHHCCCCCCCEEEECCC
GGSPLQAQVVRGKGYPTFCPTGPWLFTTGSDTTFETFDFELRINGELRQSGSTVDMTLGF
CCCCCEEEEEECCCCCCCCCCCCEEEECCCCCEEEEEEEEEEECCHHHCCCCEEEEECCH
AEVVETVSATIALRAGDIILTGTPGGCGFQFDPPRYLRPGDVIEAHSAKLGKMRLPVHDE
HHHHHHHHHEEEEEECCEEEECCCCCCCCCCCCCCCCCCCCEEECCCCCCCEEECCCCCC
KPIESASR
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353931; 9384377 [H]