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The map label for this gene is maoC [H]

Identifier: 169627999

GI number: 169627999

Start: 892408

End: 894444

Strand: Reverse

Name: maoC [H]

Synonym: MAB_0900c

Alternate gene names: 169627999

Gene position: 894444-892408 (Counterclockwise)

Preceding gene: 169628000

Following gene: 169627998

Centisome position: 17.65

GC content: 65.64

Gene sequence:

>2037_bases
ATGACAGCTGTGCTGCAGAGCTACATAACCGGAAAGTGGACGACCCCCGAAGGGGATGCTGATCCGCTGGTCAATGCCGC
TACCGGCGACGAAGTGGCCCGATACGCCGTGGGCTCGGTGGACCTTGCCGCCGTCGTCGCCTATGGCCGCGAAGTCGGCG
GCCCCGCCCTGCGCGCGTTGACCTTCCACCAGCGCGCGGCCGCGCTGAAGGCCTTGGCCAAGCAGTTGATGGCAGCCAAG
AACGATTTCTATCCGCTGTCCGCGGCCACCGGCGCCACCGCGCGTGACTCCGCCGTCGACATCGACGGCGGCTTCGGCAC
GCTGTTCAGCTATGCCAGCAAAGGCGTTCGCGAGCTTCCCAACGACACCATCTATCTCGACGGTGCCTCCGAATCACTCG
GCCGTGCAGGGACATTCGTTGGCCAGCACATCTACACCTCGCGGCCGGGTGTCGCGGTCCAGATCAACGCCTTCAACTTT
CCGGTGTGGGGCATGCTGGAAAAGCTGGCTCCGGCGTTCCTCGCCGGCGTGCCGTCGATCGTCAAACCGGCGCACCAGAC
CGCTTACCTCACCGAACTCGTGTTCCGGGCGATCATCGATTCCGGACTCCTGCCCGAGGGATCGGTACAGCTGTTGTGCG
TCCGCTCGCACGAACTGCTCGATCATCTTGACGGCCAAGACACCGTGCTGTTCACCGGTTCCGCCGCTACCGCGGCCAAG
CTGCGGAGCCACCGCAACGTGGTGGCTGGCGGTGTGCGGCTCAACGCCGAAGCCGACTCGTTGAACTGCTCGATCCTGGG
CCCCGACGCGACACCCGGCACGCCCGAATTCGACTTGTACATCAAACAACTCGTCGCCGAGATGACTACCAAGGCCGGTC
AGAAGTGCACAGCTATCCGCCGCGCCCTGGTGCCCGAAGCATTGGTCGATGCCGCGGTCACCGCCACTTCAGAACGCTTG
TCCAAGGTCGTCGTCGGCAACCCGGAACTCGACAGCGTGCGGATGGGCGCGTTGGCCAGCATTGACCAGCGCGACGAGGT
CCTGCGGTCACTGAAGCTGCTTCAAGACTCAGCCACACTGGTTTTCGGCGACCCCGCGTCGTTCACCGTCGAAGGCGCCG
ACGCTGCGCAGGGCGCATTTCTGCCGCCGCTGCTGCTGCGCGCCGAGGATCCCACCGCCGCGGCGGTGCACGAGGTGGAA
GCGTTCGGGCCGGTCAGCACCGTCATCGGATACCGCGACCTCGACGATGCCGTCGAGCTGGCGGCACGAGGGCAAGGCAG
CCTCGTCGGATCATTGGTCACCCACGATCCCGAGGTGGCCCGCAAGGTGACGATCGGTATCGCAGCTCACCACGGACGTA
TCCTCGTCCTCGATCGTGACGACGCCAAGGAGTCGACCGGCCACGGCTCCCCGTTGCCGACGCTGGTGCACGGCGGGCCC
GGCCGCGCCGGCGGCGGTGAAGAGCTCGGCGGTATCCGCGGCGTCCTGCATTTCATGCAGCGCACCGCAATCCAGGCGAG
CCCCGACATGCTGACGGCCATCACCGGACGCTGGACCACAGGCTCGGCCCGGACCGCCACAGAGGTGCATCCGTTCCGCA
AGCACCTCGAAGAATTGCAGATCGGTGACACCATCGTTGGCGGCCCCCGAGTGGTCAGCCTCGAAGACATCGACCATTTC
GCCGAGTTCACCGGGGACACCTTCTATGCGCATACCGATCCTGATGCCGCGGCACGCAACCCGTTGTTCGGCGGGATCGT
CGCGCACGGGTATCTCGTCGTGTCGCTGGCCGCGGGTCTATTCGTCGAGCCCAATCCGGGTCCCGTGCTCGCCAACTTCG
GTGTGGACGGCCTGCGATTCTTGACGCCGGTCAAACCCGGTGACGCGCTGACGGTCACCTTGACCGCCAAGCAACTGACG
CCCCGACTGTCTGCCGACTACGGCGAAGTCCGTTGGGACGCCGTGGTCACCAACCAGAACGACGACCCGGTCGCCACCTA
CGACGTGCTGACACTGGTCGCCAAGAAAGAGAGCTGA

Upstream 100 bases:

>100_bases
TTCGGTCGGCCACAACACCCCCTGCCAGATCTTGACGCGCACCCGCTCCTGCTGCCAAGGTCATTACCGAACGAATGGAC
GGTTGGTAAGGAGTGTGACA

Downstream 100 bases:

>100_bases
ATTGTCATATTCGAAGGAAGGCAATATGTTTCGTATCTCCGTGTGCTACGGGCAACCCACTGACCCGGAAGCATTCGATG
ACTATTACGGGCAAACCCAC

Product: bifunctional aldehyde dehydrogenase/enoyl-CoA hydratase

Products: NA

Alternate protein names: Phenylacetic acid degradation protein paaZ [H]

Number of amino acids: Translated: 678; Mature: 677

Protein sequence:

>678_residues
MTAVLQSYITGKWTTPEGDADPLVNAATGDEVARYAVGSVDLAAVVAYGREVGGPALRALTFHQRAAALKALAKQLMAAK
NDFYPLSAATGATARDSAVDIDGGFGTLFSYASKGVRELPNDTIYLDGASESLGRAGTFVGQHIYTSRPGVAVQINAFNF
PVWGMLEKLAPAFLAGVPSIVKPAHQTAYLTELVFRAIIDSGLLPEGSVQLLCVRSHELLDHLDGQDTVLFTGSAATAAK
LRSHRNVVAGGVRLNAEADSLNCSILGPDATPGTPEFDLYIKQLVAEMTTKAGQKCTAIRRALVPEALVDAAVTATSERL
SKVVVGNPELDSVRMGALASIDQRDEVLRSLKLLQDSATLVFGDPASFTVEGADAAQGAFLPPLLLRAEDPTAAAVHEVE
AFGPVSTVIGYRDLDDAVELAARGQGSLVGSLVTHDPEVARKVTIGIAAHHGRILVLDRDDAKESTGHGSPLPTLVHGGP
GRAGGGEELGGIRGVLHFMQRTAIQASPDMLTAITGRWTTGSARTATEVHPFRKHLEELQIGDTIVGGPRVVSLEDIDHF
AEFTGDTFYAHTDPDAAARNPLFGGIVAHGYLVVSLAAGLFVEPNPGPVLANFGVDGLRFLTPVKPGDALTVTLTAKQLT
PRLSADYGEVRWDAVVTNQNDDPVATYDVLTLVAKKES

Sequences:

>Translated_678_residues
MTAVLQSYITGKWTTPEGDADPLVNAATGDEVARYAVGSVDLAAVVAYGREVGGPALRALTFHQRAAALKALAKQLMAAK
NDFYPLSAATGATARDSAVDIDGGFGTLFSYASKGVRELPNDTIYLDGASESLGRAGTFVGQHIYTSRPGVAVQINAFNF
PVWGMLEKLAPAFLAGVPSIVKPAHQTAYLTELVFRAIIDSGLLPEGSVQLLCVRSHELLDHLDGQDTVLFTGSAATAAK
LRSHRNVVAGGVRLNAEADSLNCSILGPDATPGTPEFDLYIKQLVAEMTTKAGQKCTAIRRALVPEALVDAAVTATSERL
SKVVVGNPELDSVRMGALASIDQRDEVLRSLKLLQDSATLVFGDPASFTVEGADAAQGAFLPPLLLRAEDPTAAAVHEVE
AFGPVSTVIGYRDLDDAVELAARGQGSLVGSLVTHDPEVARKVTIGIAAHHGRILVLDRDDAKESTGHGSPLPTLVHGGP
GRAGGGEELGGIRGVLHFMQRTAIQASPDMLTAITGRWTTGSARTATEVHPFRKHLEELQIGDTIVGGPRVVSLEDIDHF
AEFTGDTFYAHTDPDAAARNPLFGGIVAHGYLVVSLAAGLFVEPNPGPVLANFGVDGLRFLTPVKPGDALTVTLTAKQLT
PRLSADYGEVRWDAVVTNQNDDPVATYDVLTLVAKKES
>Mature_677_residues
TAVLQSYITGKWTTPEGDADPLVNAATGDEVARYAVGSVDLAAVVAYGREVGGPALRALTFHQRAAALKALAKQLMAAKN
DFYPLSAATGATARDSAVDIDGGFGTLFSYASKGVRELPNDTIYLDGASESLGRAGTFVGQHIYTSRPGVAVQINAFNFP
VWGMLEKLAPAFLAGVPSIVKPAHQTAYLTELVFRAIIDSGLLPEGSVQLLCVRSHELLDHLDGQDTVLFTGSAATAAKL
RSHRNVVAGGVRLNAEADSLNCSILGPDATPGTPEFDLYIKQLVAEMTTKAGQKCTAIRRALVPEALVDAAVTATSERLS
KVVVGNPELDSVRMGALASIDQRDEVLRSLKLLQDSATLVFGDPASFTVEGADAAQGAFLPPLLLRAEDPTAAAVHEVEA
FGPVSTVIGYRDLDDAVELAARGQGSLVGSLVTHDPEVARKVTIGIAAHHGRILVLDRDDAKESTGHGSPLPTLVHGGPG
RAGGGEELGGIRGVLHFMQRTAIQASPDMLTAITGRWTTGSARTATEVHPFRKHLEELQIGDTIVGGPRVVSLEDIDHFA
EFTGDTFYAHTDPDAAARNPLFGGIVAHGYLVVSLAAGLFVEPNPGPVLANFGVDGLRFLTPVKPGDALTVTLTAKQLTP
RLSADYGEVRWDAVVTNQNDDPVATYDVLTLVAKKES

Specific function: Phenylacetic acid aerobic catabolism. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI25777724, Length=500, Percent_Identity=24.4, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI21361176, Length=496, Percent_Identity=24.7983870967742, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI25777728, Length=352, Percent_Identity=25.5681818181818, Blast_Score=89, Evalue=2e-17,
Organism=Homo sapiens, GI25777730, Length=506, Percent_Identity=25.8893280632411, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI25777732, Length=503, Percent_Identity=25.2485089463221, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI153266822, Length=351, Percent_Identity=24.5014245014245, Blast_Score=70, Evalue=6e-12,
Organism=Escherichia coli, GI1787653, Length=678, Percent_Identity=51.4749262536873, Blast_Score=631, Evalue=0.0,
Organism=Escherichia coli, GI1787684, Length=449, Percent_Identity=26.0579064587973, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI1787250, Length=450, Percent_Identity=25.7777777777778, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI87082295, Length=375, Percent_Identity=25.6, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1789015, Length=464, Percent_Identity=25, Blast_Score=76, Evalue=7e-15,
Organism=Escherichia coli, GI87081926, Length=352, Percent_Identity=24.4318181818182, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1786504, Length=497, Percent_Identity=27.364185110664, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI1787558, Length=467, Percent_Identity=23.5546038543897, Blast_Score=71, Evalue=3e-13,
Organism=Escherichia coli, GI1788042, Length=456, Percent_Identity=25.6578947368421, Blast_Score=64, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI25143876, Length=448, Percent_Identity=23.8839285714286, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17562198, Length=501, Percent_Identity=24.1516966067864, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI25143874, Length=448, Percent_Identity=23.8839285714286, Blast_Score=84, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI32564736, Length=376, Percent_Identity=25.7978723404255, Blast_Score=72, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI25144435, Length=375, Percent_Identity=25.6, Blast_Score=72, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI71986308, Length=394, Percent_Identity=24.8730964467005, Blast_Score=65, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6323822, Length=505, Percent_Identity=24.3564356435644, Blast_Score=89, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6323821, Length=505, Percent_Identity=23.960396039604, Blast_Score=84, Evalue=8e-17,
Organism=Saccharomyces cerevisiae, GI6324950, Length=372, Percent_Identity=24.4623655913978, Blast_Score=80, Evalue=9e-16,
Organism=Saccharomyces cerevisiae, GI6320917, Length=348, Percent_Identity=25, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI20129399, Length=308, Percent_Identity=27.5974025974026, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI24650465, Length=359, Percent_Identity=25.0696378830084, Blast_Score=66, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR002539
- InterPro:   IPR011966 [H]

Pfam domain/function: PF00171 Aldedh; PF01575 MaoC_dehydratas [H]

EC number: NA

Molecular weight: Translated: 71288; Mature: 71157

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAVLQSYITGKWTTPEGDADPLVNAATGDEVARYAVGSVDLAAVVAYGREVGGPALRAL
CHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHH
TFHQRAAALKALAKQLMAAKNDFYPLSAATGATARDSAVDIDGGFGTLFSYASKGVRELP
HHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHCC
NDTIYLDGASESLGRAGTFVGQHIYTSRPGVAVQINAFNFPVWGMLEKLAPAFLAGVPSI
CCEEEECCCCHHHCCHHHHHHHHHEECCCCEEEEEEEECCCHHHHHHHHHHHHHHCCCHH
VKPAHQTAYLTELVFRAIIDSGLLPEGSVQLLCVRSHELLDHLDGQDTVLFTGSAATAAK
HCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHCCCCCEEEEECCCHHHHH
LRSHRNVVAGGVRLNAEADSLNCSILGPDATPGTPEFDLYIKQLVAEMTTKAGQKCTAIR
HHHCCCEEECCEEEECCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHH
RALVPEALVDAAVTATSERLSKVVVGNPELDSVRMGALASIDQRDEVLRSLKLLQDSATL
HHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCHHHHHHCCCHHHHHHHHHHHHHCCCCE
VFGDPASFTVEGADAAQGAFLPPLLLRAEDPTAAAVHEVEAFGPVSTVIGYRDLDDAVEL
EEECCCCEEECCCCCCCCCCCCCEEEECCCCCHHHHHHHHHCCCHHHHHCCCCHHHHHHH
AARGQGSLVGSLVTHDPEVARKVTIGIAAHHGRILVLDRDDAKESTGHGSPLPTLVHGGP
HHCCCCCEEEHHHHCCHHHHHEEEEEEEECCCEEEEEECCCCCCCCCCCCCCCEEEECCC
GRAGGGEELGGIRGVLHFMQRTAIQASPDMLTAITGRWTTGSARTATEVHPFRKHLEELQ
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHH
IGDTIVGGPRVVSLEDIDHFAEFTGDTFYAHTDPDAAARNPLFGGIVAHGYLVVSLAAGL
CCCEEECCCEEEEHHHHHHHHHHCCCEEEEECCCCHHHCCCCCHHHHHHHHHHHHHHCCE
FVEPNPGPVLANFGVDGLRFLTPVKPGDALTVTLTAKQLTPRLSADYGEVRWDAVVTNQN
EECCCCCCEEEECCCCCEEEECCCCCCCEEEEEEEHHHCCCCCCCCCCCEEEEEEEECCC
DDPVATYDVLTLVAKKES
CCCCHHHHHHHHEECCCC
>Mature Secondary Structure 
TAVLQSYITGKWTTPEGDADPLVNAATGDEVARYAVGSVDLAAVVAYGREVGGPALRAL
HHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHH
TFHQRAAALKALAKQLMAAKNDFYPLSAATGATARDSAVDIDGGFGTLFSYASKGVRELP
HHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHCC
NDTIYLDGASESLGRAGTFVGQHIYTSRPGVAVQINAFNFPVWGMLEKLAPAFLAGVPSI
CCEEEECCCCHHHCCHHHHHHHHHEECCCCEEEEEEEECCCHHHHHHHHHHHHHHCCCHH
VKPAHQTAYLTELVFRAIIDSGLLPEGSVQLLCVRSHELLDHLDGQDTVLFTGSAATAAK
HCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHCCCCCEEEEECCCHHHHH
LRSHRNVVAGGVRLNAEADSLNCSILGPDATPGTPEFDLYIKQLVAEMTTKAGQKCTAIR
HHHCCCEEECCEEEECCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHH
RALVPEALVDAAVTATSERLSKVVVGNPELDSVRMGALASIDQRDEVLRSLKLLQDSATL
HHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCHHHHHHCCCHHHHHHHHHHHHHCCCCE
VFGDPASFTVEGADAAQGAFLPPLLLRAEDPTAAAVHEVEAFGPVSTVIGYRDLDDAVEL
EEECCCCEEECCCCCCCCCCCCCEEEECCCCCHHHHHHHHHCCCHHHHHCCCCHHHHHHH
AARGQGSLVGSLVTHDPEVARKVTIGIAAHHGRILVLDRDDAKESTGHGSPLPTLVHGGP
HHCCCCCEEEHHHHCCHHHHHEEEEEEEECCCEEEEEECCCCCCCCCCCCCCCEEEECCC
GRAGGGEELGGIRGVLHFMQRTAIQASPDMLTAITGRWTTGSARTATEVHPFRKHLEELQ
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHH
IGDTIVGGPRVVSLEDIDHFAEFTGDTFYAHTDPDAAARNPLFGGIVAHGYLVVSLAAGL
CCCEEECCCEEEEHHHHHHHHHHCCCEEEEECCCCHHHCCCCCHHHHHHHHHHHHHHCCE
FVEPNPGPVLANFGVDGLRFLTPVKPGDALTVTLTAKQLTPRLSADYGEVRWDAVVTNQN
EECCCCCCEEEECCCCCEEEECCCCCCCEEEEEEEHHHCCCCCCCCCCCEEEEEEEECCC
DDPVATYDVLTLVAKKES
CCCCHHHHHHHHEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9748275; 9097039; 9278503; 10766858 [H]