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The map label for this gene is moaC2 [H]

Identifier: 169627963

GI number: 169627963

Start: 863530

End: 864042

Strand: Direct

Name: moaC2 [H]

Synonym: MAB_0864

Alternate gene names: 169627963

Gene position: 863530-864042 (Clockwise)

Preceding gene: 169627962

Following gene: 169627964

Centisome position: 17.04

GC content: 65.5

Gene sequence:

>513_bases
GTGCCTGAGGGTCTTCGCGCAAGCGGCTCATCCGGGCCCGAGGGGCTCTCCCATATCGATGAGCACGGGTCCGCGCACAT
GGTCGACGTGTCGGCCAAGCAGGCCACCGCACGCGAGGCCGTCGCGGCGGGGCGCTTTGTCACTACTCCCGAGGTTCTGA
AGCTTCTCTCAGACGGCACGTTGCCCAAGGGCGACGCCATCGCCACTGCCCGTCTGGCCGCCATCATGGCCGCCAAACGC
ACCAGCGAACTCATCCCGCTGTGTCATCAGATACCGCTGACCGGTATCGAGGTGGATTTCGCGATCGATGCCACCGCGGG
ATCCATTCAGATCACGGCTGTCGCCCGCACCAAGGACCGCACCGGGGTCGAGATGGAGGCGCTGACCGCGGTGACGGTTG
CCGGCCTGACCTTGCACGACATGGTCAAGGCCGTCGATCCCGCCTCACGTATCGACGACGTCAGGGTGCTACGCAAAGAG
GGCGGTAAGACCGGAACATGGACCCGACCCTGA

Upstream 100 bases:

>100_bases
GCCGACCGCACCGGAGCGCTCTCACCGTTCGGTGACCTTGAGTTCCCGGTGGAGTCCGTGCCCTACGTGCACCCCGTCAC
CGTCATCAACAAGTAGAGCG

Downstream 100 bases:

>100_bases
GATCGGCGCGGGTGATCGTGGCCTCCACTCGGGCGGCAACCGGTCAGTACACCGATAGGACAGGCCCCATCATCGTCGAA
TGGCTTGGTGCACAAGGATT

Product: molybdenum cofactor biosynthesis protein MoaC2

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 170; Mature: 169

Protein sequence:

>170_residues
MPEGLRASGSSGPEGLSHIDEHGSAHMVDVSAKQATAREAVAAGRFVTTPEVLKLLSDGTLPKGDAIATARLAAIMAAKR
TSELIPLCHQIPLTGIEVDFAIDATAGSIQITAVARTKDRTGVEMEALTAVTVAGLTLHDMVKAVDPASRIDDVRVLRKE
GGKTGTWTRP

Sequences:

>Translated_170_residues
MPEGLRASGSSGPEGLSHIDEHGSAHMVDVSAKQATAREAVAAGRFVTTPEVLKLLSDGTLPKGDAIATARLAAIMAAKR
TSELIPLCHQIPLTGIEVDFAIDATAGSIQITAVARTKDRTGVEMEALTAVTVAGLTLHDMVKAVDPASRIDDVRVLRKE
GGKTGTWTRP
>Mature_169_residues
PEGLRASGSSGPEGLSHIDEHGSAHMVDVSAKQATAREAVAAGRFVTTPEVLKLLSDGTLPKGDAIATARLAAIMAAKRT
SELIPLCHQIPLTGIEVDFAIDATAGSIQITAVARTKDRTGVEMEALTAVTVAGLTLHDMVKAVDPASRIDDVRVLRKEG
GKTGTWTRP

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family [H]

Homologues:

Organism=Escherichia coli, GI1787001, Length=152, Percent_Identity=49.3421052631579, Blast_Score=137, Evalue=5e-34,
Organism=Caenorhabditis elegans, GI32566331, Length=153, Percent_Identity=41.8300653594771, Blast_Score=126, Evalue=6e-30,
Organism=Drosophila melanogaster, GI28574490, Length=148, Percent_Identity=47.2972972972973, Blast_Score=131, Evalue=3e-31,
Organism=Drosophila melanogaster, GI28574492, Length=137, Percent_Identity=47.4452554744526, Blast_Score=120, Evalue=4e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820 [H]

Pfam domain/function: PF01967 MoaC [H]

EC number: NA

Molecular weight: Translated: 17731; Mature: 17600

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPEGLRASGSSGPEGLSHIDEHGSAHMVDVSAKQATAREAVAAGRFVTTPEVLKLLSDGT
CCCCCCCCCCCCCHHHHHHHHCCCEEEEECCHHHHHHHHHHHCCCCCCCHHHHHHHHCCC
LPKGDAIATARLAAIMAAKRTSELIPLCHQIPLTGIEVDFAIDATAGSIQITAVARTKDR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCEEEEEEEEECCCC
TGVEMEALTAVTVAGLTLHDMVKAVDPASRIDDVRVLRKEGGKTGTWTRP
CCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
PEGLRASGSSGPEGLSHIDEHGSAHMVDVSAKQATAREAVAAGRFVTTPEVLKLLSDGT
CCCCCCCCCCCCHHHHHHHHCCCEEEEECCHHHHHHHHHHHCCCCCCCHHHHHHHHCCC
LPKGDAIATARLAAIMAAKRTSELIPLCHQIPLTGIEVDFAIDATAGSIQITAVARTKDR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCEEEEEEEEECCCC
TGVEMEALTAVTVAGLTLHDMVKAVDPASRIDDVRVLRKEGGKTGTWTRP
CCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]