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The map label for this gene is betA [H]

Identifier: 169627915

GI number: 169627915

Start: 806879

End: 808387

Strand: Direct

Name: betA [H]

Synonym: MAB_0816

Alternate gene names: 169627915

Gene position: 806879-808387 (Clockwise)

Preceding gene: 169627914

Following gene: 169627916

Centisome position: 15.92

GC content: 63.68

Gene sequence:

>1509_bases
GTGCTCAACAGGTTTGACGTCGCGGTTGTCGGCGGCGGGACCGCCGGATGTGCGGTGGCCGCGCGCCTGGCAGGCAGCGG
CAGGAAGGTGCTCGTGCTAGAGGCCGGCCCAGACTATGGGCATGCGTTGTCCGGTCGTTGGCCGGCGGACCTGCTGTCGG
CCGCCACTATCCCCAGTTCACATGATTGGGGTTACCGGGGAACCGGAGCGGGCGGGCAGCATCTGGAGTTCGAACGCTGC
CGGGTCATCGGAGGGTGTTCGACTCACAACGGCGCCACACAGAACGTGGGCTGGGGCGGCGACTATGACCGTTGGGCTGC
AACGGGACTGACCGGGTGGAGCTCGTCGGAGCTGGAGCCGTTCTTCGAGCTGGCAGGCAAGGCGCTGAATCTGCGGAACT
ATCGAGACGAGCAGCTCCAACCGCTCCAAACCGCCTTCGTGGCCGCGGTCGTTGACCAGGGCCTCGAAGAGCGCAACGAC
TTTCTGTCTATGAACGGCAGTGCAGGAGTCGGCTATTCGCCGGTCAGCATCACCGATGACGGCACCCGCTACAACACCGC
TTTCGCCTATCTTGATGATCTTCGCGAATCGGGCAGGCTGACGGTACTCGGTGGCGTGGAGGTCACCGGCATACGGCTCG
AACAGGGCCGAGCGGTCGGTGTCTACGTGTACGCGCCGGATCGCACTGCGCCGGAACCCGCACTGGTCTATGCCGATACG
GTGGTACTAAGTGCGGGGGCCTATGGAACCCCTGAGCTGCTGCTGCGATCGGGTATCGGCCCCGCGGGTGAGCTCGCCGG
AGTCGGCGTGCCGGTGCAATGCGACCTTCCCGGTGTGGGGAAAGGGCTGCAGGATCATCCCTCACTGCAACTCGAATACG
CCGCCACCCGTGAACTTGCCGATGCCCTCGCGGAATTCATGAGCAGACAATGGCTTCCGGATGAGCAAGCCATTGCCAAG
GTGAAGTCGCCGGAGGCCGGTGACGCACCGTTCGACCTACACATCTACCCATGGACGGAGCGCGATCCGGCAAGCCCACA
TGGCTGGCGATGCGTGGTGCCGATCGGGTTGGTCAAGCCGCGCTCGCGTGGCGCCTTGACTCTCAGGCTGGTGGGCGGAG
AACTGAAGACTGAAGTGAACCACGGCTATCTGGCTGACCCGCGCGATGTGAACGCCATGCGTTACGGCATGGAATGGGCT
GAGGAGATCATTGATACGGGCATCTCGGAGTTCTCCAGATACCTTGGCCCACGGATCAATCCGATGGAGGGCCTCACCAC
GGACTGGATTGCGGCCAATCATCGGCACTATTGGCACCCGGTAGGCACCTGCACGATGGGCATGCCTGCCACCGGTGGGG
TCGTCGACCATCGCGGCGCCGTGCATGGAATCGACAACCTGTACATCGCCGATGCCTCGGTGTTCCCGGACATCCCGCGG
GGTACCACGGCCCTCCCGACCACCGTTGTCGGTGAACGCATCGCAAGTTTTCTCATGGAGGACAACTGA

Upstream 100 bases:

>100_bases
GTGTTCGGTAAACGGCCAACGGCGGCTCGCCGAGACATGTCTTCGCCGCAGGACGGCGTTCCCGGCATCACTAACGAAAA
GGAAAGTATCGGTGCATAAC

Downstream 100 bases:

>100_bases
CATGGCCAAGGTTTTGTACGGAAACGGCACTGAAATCGTGGACCCACGCACGGGAGAGGGCTATGAGTTTCAGCCCGACT
CGACCCACGGTGAGGTCGAC

Product: glucose-methanol-choline oxidoreductase

Products: NA

Alternate protein names: CDH; CHD [H]

Number of amino acids: Translated: 502; Mature: 502

Protein sequence:

>502_residues
MLNRFDVAVVGGGTAGCAVAARLAGSGRKVLVLEAGPDYGHALSGRWPADLLSAATIPSSHDWGYRGTGAGGQHLEFERC
RVIGGCSTHNGATQNVGWGGDYDRWAATGLTGWSSSELEPFFELAGKALNLRNYRDEQLQPLQTAFVAAVVDQGLEERND
FLSMNGSAGVGYSPVSITDDGTRYNTAFAYLDDLRESGRLTVLGGVEVTGIRLEQGRAVGVYVYAPDRTAPEPALVYADT
VVLSAGAYGTPELLLRSGIGPAGELAGVGVPVQCDLPGVGKGLQDHPSLQLEYAATRELADALAEFMSRQWLPDEQAIAK
VKSPEAGDAPFDLHIYPWTERDPASPHGWRCVVPIGLVKPRSRGALTLRLVGGELKTEVNHGYLADPRDVNAMRYGMEWA
EEIIDTGISEFSRYLGPRINPMEGLTTDWIAANHRHYWHPVGTCTMGMPATGGVVDHRGAVHGIDNLYIADASVFPDIPR
GTTALPTTVVGERIASFLMEDN

Sequences:

>Translated_502_residues
MLNRFDVAVVGGGTAGCAVAARLAGSGRKVLVLEAGPDYGHALSGRWPADLLSAATIPSSHDWGYRGTGAGGQHLEFERC
RVIGGCSTHNGATQNVGWGGDYDRWAATGLTGWSSSELEPFFELAGKALNLRNYRDEQLQPLQTAFVAAVVDQGLEERND
FLSMNGSAGVGYSPVSITDDGTRYNTAFAYLDDLRESGRLTVLGGVEVTGIRLEQGRAVGVYVYAPDRTAPEPALVYADT
VVLSAGAYGTPELLLRSGIGPAGELAGVGVPVQCDLPGVGKGLQDHPSLQLEYAATRELADALAEFMSRQWLPDEQAIAK
VKSPEAGDAPFDLHIYPWTERDPASPHGWRCVVPIGLVKPRSRGALTLRLVGGELKTEVNHGYLADPRDVNAMRYGMEWA
EEIIDTGISEFSRYLGPRINPMEGLTTDWIAANHRHYWHPVGTCTMGMPATGGVVDHRGAVHGIDNLYIADASVFPDIPR
GTTALPTTVVGERIASFLMEDN
>Mature_502_residues
MLNRFDVAVVGGGTAGCAVAARLAGSGRKVLVLEAGPDYGHALSGRWPADLLSAATIPSSHDWGYRGTGAGGQHLEFERC
RVIGGCSTHNGATQNVGWGGDYDRWAATGLTGWSSSELEPFFELAGKALNLRNYRDEQLQPLQTAFVAAVVDQGLEERND
FLSMNGSAGVGYSPVSITDDGTRYNTAFAYLDDLRESGRLTVLGGVEVTGIRLEQGRAVGVYVYAPDRTAPEPALVYADT
VVLSAGAYGTPELLLRSGIGPAGELAGVGVPVQCDLPGVGKGLQDHPSLQLEYAATRELADALAEFMSRQWLPDEQAIAK
VKSPEAGDAPFDLHIYPWTERDPASPHGWRCVVPIGLVKPRSRGALTLRLVGGELKTEVNHGYLADPRDVNAMRYGMEWA
EEIIDTGISEFSRYLGPRINPMEGLTTDWIAANHRHYWHPVGTCTMGMPATGGVVDHRGAVHGIDNLYIADASVFPDIPR
GTTALPTTVVGERIASFLMEDN

Specific function: Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine [H]

COG id: COG2303

COG function: function code E; Choline dehydrogenase and related flavoproteins

Gene ontology:

Cell location: Membrane-Bound [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GMC oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI217272839, Length=544, Percent_Identity=29.5955882352941, Blast_Score=176, Evalue=4e-44,
Organism=Escherichia coli, GI1786503, Length=544, Percent_Identity=28.125, Blast_Score=165, Evalue=7e-42,
Organism=Caenorhabditis elegans, GI17532301, Length=549, Percent_Identity=25.5009107468124, Blast_Score=154, Evalue=9e-38,
Organism=Drosophila melanogaster, GI18859995, Length=573, Percent_Identity=28.6212914485166, Blast_Score=153, Evalue=3e-37,
Organism=Drosophila melanogaster, GI17137792, Length=548, Percent_Identity=27.5547445255474, Blast_Score=147, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24642042, Length=573, Percent_Identity=27.3996509598604, Blast_Score=145, Evalue=6e-35,
Organism=Drosophila melanogaster, GI45549471, Length=583, Percent_Identity=26.9296740994854, Blast_Score=141, Evalue=1e-33,
Organism=Drosophila melanogaster, GI45551458, Length=583, Percent_Identity=26.9296740994854, Blast_Score=141, Evalue=1e-33,
Organism=Drosophila melanogaster, GI24650267, Length=573, Percent_Identity=28.6212914485166, Blast_Score=133, Evalue=3e-31,
Organism=Drosophila melanogaster, GI18859993, Length=570, Percent_Identity=27.719298245614, Blast_Score=132, Evalue=6e-31,
Organism=Drosophila melanogaster, GI24642035, Length=591, Percent_Identity=27.2419627749577, Blast_Score=129, Evalue=4e-30,
Organism=Drosophila melanogaster, GI24642037, Length=587, Percent_Identity=26.4054514480409, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24642048, Length=305, Percent_Identity=33.7704918032787, Blast_Score=115, Evalue=7e-26,
Organism=Drosophila melanogaster, GI24642051, Length=298, Percent_Identity=32.8859060402685, Blast_Score=112, Evalue=6e-25,
Organism=Drosophila melanogaster, GI24642055, Length=343, Percent_Identity=30.3206997084548, Blast_Score=107, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24642039, Length=323, Percent_Identity=30.9597523219814, Blast_Score=106, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24642059, Length=310, Percent_Identity=30.6451612903226, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24645930, Length=301, Percent_Identity=26.578073089701, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011533
- InterPro:   IPR012132
- InterPro:   IPR000172
- InterPro:   IPR007867 [H]

Pfam domain/function: PF05199 GMC_oxred_C; PF00732 GMC_oxred_N [H]

EC number: =1.1.99.1 [H]

Molecular weight: Translated: 53744; Mature: 53744

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00624 GMC_OXRED_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNRFDVAVVGGGTAGCAVAARLAGSGRKVLVLEAGPDYGHALSGRWPADLLSAATIPSS
CCCEEEEEEECCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHCCCCC
HDWGYRGTGAGGQHLEFERCRVIGGCSTHNGATQNVGWGGDYDRWAATGLTGWSSSELEP
CCCCCCCCCCCCCCCCHHHEEEEECCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCH
FFELAGKALNLRNYRDEQLQPLQTAFVAAVVDQGLEERNDFLSMNGSAGVGYSPVSITDD
HHHHCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCEEECCC
GTRYNTAFAYLDDLRESGRLTVLGGVEVTGIRLEQGRAVGVYVYAPDRTAPEPALVYADT
CCEEHHHHHHHHHHHHCCCEEEEECEEEEEEEEECCCEEEEEEECCCCCCCCCEEEEEEE
VVLSAGAYGTPELLLRSGIGPAGELAGVGVPVQCDLPGVGKGLQDHPSLQLEYAATRELA
EEEECCCCCCHHHHHHCCCCCCHHHCCCCCEEEECCCCCCCCCCCCCCEEEEHHHHHHHH
DALAEFMSRQWLPDEQAIAKVKSPEAGDAPFDLHIYPWTERDPASPHGWRCVVPIGLVKP
HHHHHHHHHCCCCCHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCCCCEEEEEEECCCC
RSRGALTLRLVGGELKTEVNHGYLADPRDVNAMRYGMEWAEEIIDTGISEFSRYLGPRIN
CCCCCEEEEEECCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHCCCCC
PMEGLTTDWIAANHRHYWHPVGTCTMGMPATGGVVDHRGAVHGIDNLYIADASVFPDIPR
CCCCCCCHHEECCCCEEECCCCEEECCCCCCCCEECCCCCCCCCCCEEEECHHHCCCCCC
GTTALPTTVVGERIASFLMEDN
CCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLNRFDVAVVGGGTAGCAVAARLAGSGRKVLVLEAGPDYGHALSGRWPADLLSAATIPSS
CCCEEEEEEECCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHCCCCC
HDWGYRGTGAGGQHLEFERCRVIGGCSTHNGATQNVGWGGDYDRWAATGLTGWSSSELEP
CCCCCCCCCCCCCCCCHHHEEEEECCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCH
FFELAGKALNLRNYRDEQLQPLQTAFVAAVVDQGLEERNDFLSMNGSAGVGYSPVSITDD
HHHHCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCEEECCC
GTRYNTAFAYLDDLRESGRLTVLGGVEVTGIRLEQGRAVGVYVYAPDRTAPEPALVYADT
CCEEHHHHHHHHHHHHCCCEEEEECEEEEEEEEECCCEEEEEEECCCCCCCCCEEEEEEE
VVLSAGAYGTPELLLRSGIGPAGELAGVGVPVQCDLPGVGKGLQDHPSLQLEYAATRELA
EEEECCCCCCHHHHHHCCCCCCHHHCCCCCEEEECCCCCCCCCCCCCCEEEEHHHHHHHH
DALAEFMSRQWLPDEQAIAKVKSPEAGDAPFDLHIYPWTERDPASPHGWRCVVPIGLVKP
HHHHHHHHHCCCCCHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCCCCEEEEEEECCCC
RSRGALTLRLVGGELKTEVNHGYLADPRDVNAMRYGMEWAEEIIDTGISEFSRYLGPRIN
CCCCCEEEEEECCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHCCCCC
PMEGLTTDWIAANHRHYWHPVGTCTMGMPATGGVVDHRGAVHGIDNLYIADASVFPDIPR
CCCCCCCHHEECCCCEEECCCCEEECCCCCCCCEECCCCCCCCCCCEEEECHHHCCCCCC
GTTALPTTVVGERIASFLMEDN
CCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA