Click here to switch to the map view.

The map label for this gene is xasA [C]

Identifier: 169627914

GI number: 169627914

Start: 805297

End: 806877

Strand: Direct

Name: xasA [C]

Synonym: MAB_0815

Alternate gene names: 169627914

Gene position: 805297-806877 (Clockwise)

Preceding gene: 169627912

Following gene: 169627915

Centisome position: 15.89

GC content: 61.67

Gene sequence:

>1581_bases
ATGACGACCAGCACCAACACCGCCCCGTCCGGCTCGGGGCGCGCCCTAAATCCGACCCTTCGTCGCGTGGACGTCTTCGC
GGTATTGGTCTGTGCGTTGGTGGGTGTCGACACCCTGGGCGCGGTCAGCGCCTATGGGCCGCAAGGGCTCCTGTGGATGG
CGCTGGTCGCAGTCATCTTCTTCCTGCCGTACGGGTTGCTCACCGCGGAATTGGGGTCGGCTTTCCCTCAAGAGGGCGGC
CCCTATGTGTGGACCAAGCTTGCGTTCGGCAAGTTCGCCGCAGGTATCAATCAGTTCTTCTACTGGATCTCCAATCCGGT
GTGGATCGGTGGCACGCTCTGCATCGTCGCGGTGGTCACCTTTGAAGAGTTCTTCTTCCCGCTGCCGGGTTTGTGGAAAT
GGGTGGCCGCCGCCGTCTTCGTATGGGGTTCGGCGTGTGTGATCGGCGCCAGTGTCCGGTTTGGGCGATGGATCTTTCTG
GTGGGCGCCGCCGCACGTATCGCCCTGTTGGGGTTGTTCATCGCGTCGGTGATCGTCTATGCGTACAAGAACGGTCTGCA
GCCCATGCACACCAGCGACTTCTCCTGGACCTATGCGGGATTCGTTGCGGTGATACCCGTGATTGTCTTCAATTTCCTGG
GCTTTGAAGTGCCCTCGAACGCGGCCGAAGAGATGGTCAATCCGCAAAAGGACGTCCCGCTGACGGTGTTGCGTGGCGGA
CTGACTGCCACGTTGCTCTACGGCATCCCGGTCTTGGGAATTCTGTTGGTACTGCCCAAGAATCAGTTGGGAACCGTTAC
CGGATTCGTTGATGCGTGCCGGGCCGTGTTCACCGTGTACGGCGGTAGTGTCGCGCCGGACGGGACCGCAGAGCTGCACG
GGCTGGGACAAGCGGCCGCCCAAGTCGCGGCCGCCGGGCTGATCATCGGTCTATTCACGAGCGGTACGGCCTGGGCCATG
GGGGTCAGTCGCGCGCAAGCGGTGGCATTCACCGACGGTGCAGGGCCGGCATGGCTTGGAAAGTTTTCCGGCAACGGTTC
TCCGGCCAGGGTGAACATCATGTCGGCAGTGGTGTCGACGATCGTCATGGCGGCGGCGATGATCTTTGCCCACGGCAATG
CCGAGAAGTACTTCTCGGCGGCAATCGGATTGGTGGTGTCAGCCACCGCGATCTCCTACATCCTGACGTTCTCGTCGTTC
ATCCGCCTGCGGCACAAGTATCCGCATACCCGGCGACCGTTCCAGGTTTTCGGTGGACGGATCGGCGGCTGGATCGTCAC
GGTATTGACGGTGGGGACGATGCTGTTTACCGTCGTTTCGCTGTTCTGGCCCGGTGTGGGGGTGGGGTGGACCGGCTCCG
GGGATGATGCAGACGCATTGCTTCCGAAGGGGTTTGAGGGGCATCGGCTCGAATACACGTTGAGCCAGCTGGTCCCGATG
GCAGCCGTGTTGGGGATGGCCAGCTGTCTGTACTTGCTCGGTGTGTTCGGTAAACGGCCAACGGCGGCTCGCCGAGACAT
GTCTTCGCCGCAGGACGGCGTTCCCGGCATCACTAACGAAAAGGAAAGTATCGGTGCATAA

Upstream 100 bases:

>100_bases
AAAAGAATAGCGCGTTCGTAATAAACAACAATGCTTGACAATTATGAACGTCACCCACCACACTGGGCCGCGCAGGTGAT
CTACGGCACACGGAGGATCG

Downstream 100 bases:

>100_bases
CGTGCTCAACAGGTTTGACGTCGCGGTTGTCGGCGGCGGGACCGCCGGATGTGCGGTGGCCGCGCGCCTGGCAGGCAGCG
GCAGGAAGGTGCTCGTGCTA

Product: putative amino acid permease

Products: L-glutamate [Cytoplasm]; 4-aminobutyrate [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 526; Mature: 525

Protein sequence:

>526_residues
MTTSTNTAPSGSGRALNPTLRRVDVFAVLVCALVGVDTLGAVSAYGPQGLLWMALVAVIFFLPYGLLTAELGSAFPQEGG
PYVWTKLAFGKFAAGINQFFYWISNPVWIGGTLCIVAVVTFEEFFFPLPGLWKWVAAAVFVWGSACVIGASVRFGRWIFL
VGAAARIALLGLFIASVIVYAYKNGLQPMHTSDFSWTYAGFVAVIPVIVFNFLGFEVPSNAAEEMVNPQKDVPLTVLRGG
LTATLLYGIPVLGILLVLPKNQLGTVTGFVDACRAVFTVYGGSVAPDGTAELHGLGQAAAQVAAAGLIIGLFTSGTAWAM
GVSRAQAVAFTDGAGPAWLGKFSGNGSPARVNIMSAVVSTIVMAAAMIFAHGNAEKYFSAAIGLVVSATAISYILTFSSF
IRLRHKYPHTRRPFQVFGGRIGGWIVTVLTVGTMLFTVVSLFWPGVGVGWTGSGDDADALLPKGFEGHRLEYTLSQLVPM
AAVLGMASCLYLLGVFGKRPTAARRDMSSPQDGVPGITNEKESIGA

Sequences:

>Translated_526_residues
MTTSTNTAPSGSGRALNPTLRRVDVFAVLVCALVGVDTLGAVSAYGPQGLLWMALVAVIFFLPYGLLTAELGSAFPQEGG
PYVWTKLAFGKFAAGINQFFYWISNPVWIGGTLCIVAVVTFEEFFFPLPGLWKWVAAAVFVWGSACVIGASVRFGRWIFL
VGAAARIALLGLFIASVIVYAYKNGLQPMHTSDFSWTYAGFVAVIPVIVFNFLGFEVPSNAAEEMVNPQKDVPLTVLRGG
LTATLLYGIPVLGILLVLPKNQLGTVTGFVDACRAVFTVYGGSVAPDGTAELHGLGQAAAQVAAAGLIIGLFTSGTAWAM
GVSRAQAVAFTDGAGPAWLGKFSGNGSPARVNIMSAVVSTIVMAAAMIFAHGNAEKYFSAAIGLVVSATAISYILTFSSF
IRLRHKYPHTRRPFQVFGGRIGGWIVTVLTVGTMLFTVVSLFWPGVGVGWTGSGDDADALLPKGFEGHRLEYTLSQLVPM
AAVLGMASCLYLLGVFGKRPTAARRDMSSPQDGVPGITNEKESIGA
>Mature_525_residues
TTSTNTAPSGSGRALNPTLRRVDVFAVLVCALVGVDTLGAVSAYGPQGLLWMALVAVIFFLPYGLLTAELGSAFPQEGGP
YVWTKLAFGKFAAGINQFFYWISNPVWIGGTLCIVAVVTFEEFFFPLPGLWKWVAAAVFVWGSACVIGASVRFGRWIFLV
GAAARIALLGLFIASVIVYAYKNGLQPMHTSDFSWTYAGFVAVIPVIVFNFLGFEVPSNAAEEMVNPQKDVPLTVLRGGL
TATLLYGIPVLGILLVLPKNQLGTVTGFVDACRAVFTVYGGSVAPDGTAELHGLGQAAAQVAAAGLIIGLFTSGTAWAMG
VSRAQAVAFTDGAGPAWLGKFSGNGSPARVNIMSAVVSTIVMAAAMIFAHGNAEKYFSAAIGLVVSATAISYILTFSSFI
RLRHKYPHTRRPFQVFGGRIGGWIVTVLTVGTMLFTVVSLFWPGVGVGWTGSGDDADALLPKGFEGHRLEYTLSQLVPMA
AVLGMASCLYLLGVFGKRPTAARRDMSSPQDGVPGITNEKESIGA

Specific function: Probable Amino Acid Transporter. Involved In Extreme Acid Resistance. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Escherichia coli, GI1787768, Length=473, Percent_Identity=25.1585623678647, Blast_Score=89, Evalue=8e-19,
Organism=Escherichia coli, GI2367353, Length=364, Percent_Identity=23.3516483516484, Blast_Score=69, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 55441; Mature: 55310

Theoretical pI: Translated: 9.05; Mature: 9.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCCCCHHHCCC
>Mature Secondary Structure 
TTSTNTAPSGSGRALNPTLRRVDVFAVLVCALVGVDTLGAVSAYGPQGLLWMALVAVIF
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHHHHH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HHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 4-aminobutyrate [Cytoplasm]; L-glutamate [Periplasm] [C]

Specific reaction: 4-aminobutyrate [Cytoplasm] + L-glutamate [Periplasm] = L-glutamate [Cytoplasm] + 4-aminobutyrate [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8366052 [H]