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The map label for this gene is hbd [H]

Identifier: 169627862

GI number: 169627862

Start: 760912

End: 761805

Strand: Reverse

Name: hbd [H]

Synonym: MAB_0761c

Alternate gene names: 169627862

Gene position: 761805-760912 (Counterclockwise)

Preceding gene: 169627864

Following gene: 169627861

Centisome position: 15.03

GC content: 63.65

Gene sequence:

>894_bases
ATGAGTGATCAGCAGAAGACTATGGCCGTGGTGGGCGCCGGGGTTATCGGGCTCTCGTGGGCACGACTGGCCCGCAGCCA
CGGGTGGCGCGTCGGGATAACCGACCCCCGCGACGATCTCGACGCGGTCGTGCGAGCGGCCTTCGGCGCGGACGACTCCG
ATGTGTTCACGAGTCACACGCTCGCCGATGTGGTCGCGGAAGCCGATCTGGTCCAGGAGAACGGCCCTGAACGCCTGGCC
GTCAAACGCGAGCTGTTCGGCCAGTTTCTCGAATCAGCGCCCGAGCACGCCGTGTTGGCCACGTCCAGTTCTTCGATTGG
GGCGACCCTCATCGCCGACGGCCTCGGCGCTGGTGACCGGGTGATTGTGGGGCACCCATTCAATCCACCCGAGCTGATGC
CACTCGTCGAGGTGGTACCTGGAACCCAGACGAGTGATTCCACCCTGAATGCCGCTGTCGACCTATATCGGAAACTCGGC
CGTGCGCCGATCGTAATCCGCAAGGAGATCCCCGGTTTCGTAGCCAACCGGCTCCAGGTAGCGCTGACCCGCGAAGCGCA
GTACCTCGTCGAAGAAGGGGTGGTCAGCGTTACCGACCTCGACACCGCATTGCAGAATTCGCTTGGGTTGCGGTGGGCTG
CAACGGGATTATTCGAAGGGAACACGCTGGGCGGCGGTCCCGAGGGTGCGCGGCACCTCTACGAGGGACTCGGCGCCGAA
GTAGGAAAGATCACAATGGGAACCCCGTCGTCAGATCCGCGGGTGATCGAGAAACTGATCGAAGATATAGACACCGCCTA
CGGTACGGGACCAGAGAACTACGAACGGCTGCTCGCTCGGCGCAACGAACGCACCCGCGCGGTCTTGGCGGCACTACGCC
AGCTCGACGCCTAA

Upstream 100 bases:

>100_bases
TTGTTCCTATAGCCAGTATTCATCCCGAAACGCAGGGCGGGCAGCCGGACGGCGAGACATCCAGACAGACATTGCTGGTA
CGCACAGGAGGAGCAGGACG

Downstream 100 bases:

>100_bases
CCACGTGTTACACCACAAGGAGAACAACATGTTTCAATACTTGCTGGCCCTCAACCAGGTCAAGAGGTCCATCCTGAAGT
TCCCCACGTCCGGGGAAGAG

Product: putative 3-hydroxyacyl-CoA dehydrogenase

Products: NA

Alternate protein names: Beta-hydroxybutyryl-CoA dehydrogenase; BHBD [H]

Number of amino acids: Translated: 297; Mature: 296

Protein sequence:

>297_residues
MSDQQKTMAVVGAGVIGLSWARLARSHGWRVGITDPRDDLDAVVRAAFGADDSDVFTSHTLADVVAEADLVQENGPERLA
VKRELFGQFLESAPEHAVLATSSSSIGATLIADGLGAGDRVIVGHPFNPPELMPLVEVVPGTQTSDSTLNAAVDLYRKLG
RAPIVIRKEIPGFVANRLQVALTREAQYLVEEGVVSVTDLDTALQNSLGLRWAATGLFEGNTLGGGPEGARHLYEGLGAE
VGKITMGTPSSDPRVIEKLIEDIDTAYGTGPENYERLLARRNERTRAVLAALRQLDA

Sequences:

>Translated_297_residues
MSDQQKTMAVVGAGVIGLSWARLARSHGWRVGITDPRDDLDAVVRAAFGADDSDVFTSHTLADVVAEADLVQENGPERLA
VKRELFGQFLESAPEHAVLATSSSSIGATLIADGLGAGDRVIVGHPFNPPELMPLVEVVPGTQTSDSTLNAAVDLYRKLG
RAPIVIRKEIPGFVANRLQVALTREAQYLVEEGVVSVTDLDTALQNSLGLRWAATGLFEGNTLGGGPEGARHLYEGLGAE
VGKITMGTPSSDPRVIEKLIEDIDTAYGTGPENYERLLARRNERTRAVLAALRQLDA
>Mature_296_residues
SDQQKTMAVVGAGVIGLSWARLARSHGWRVGITDPRDDLDAVVRAAFGADDSDVFTSHTLADVVAEADLVQENGPERLAV
KRELFGQFLESAPEHAVLATSSSSIGATLIADGLGAGDRVIVGHPFNPPELMPLVEVVPGTQTSDSTLNAAVDLYRKLGR
APIVIRKEIPGFVANRLQVALTREAQYLVEEGVVSVTDLDTALQNSLGLRWAATGLFEGNTLGGGPEGARHLYEGLGAEV
GKITMGTPSSDPRVIEKLIEDIDTAYGTGPENYERLLARRNERTRAVLAALRQLDA

Specific function: Butyrate/butanol-producing pathway. Phenylacetic acid aerobic catabolism. [C]

COG id: COG1250

COG function: function code I; 3-hydroxyacyl-CoA dehydrogenase

Gene ontology:

Cell location: Mitochondria or Peroxisomes [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI115430219, Length=311, Percent_Identity=30.5466237942122, Blast_Score=142, Evalue=4e-34,
Organism=Homo sapiens, GI296179429, Length=223, Percent_Identity=34.9775784753363, Blast_Score=109, Evalue=3e-24,
Organism=Homo sapiens, GI296179427, Length=263, Percent_Identity=31.9391634980989, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI20127408, Length=309, Percent_Identity=24.9190938511327, Blast_Score=72, Evalue=8e-13,
Organism=Escherichia coli, GI1787661, Length=222, Percent_Identity=33.3333333333333, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1788682, Length=139, Percent_Identity=33.8129496402878, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1790281, Length=141, Percent_Identity=29.0780141843972, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI193203623, Length=246, Percent_Identity=34.1463414634146, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI115533614, Length=246, Percent_Identity=33.739837398374, Blast_Score=123, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17553560, Length=222, Percent_Identity=29.7297297297297, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17549919, Length=193, Percent_Identity=34.7150259067358, Blast_Score=91, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI17563036, Length=153, Percent_Identity=28.1045751633987, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI20129993, Length=264, Percent_Identity=33.3333333333333, Blast_Score=143, Evalue=1e-34,
Organism=Drosophila melanogaster, GI45549573, Length=274, Percent_Identity=32.4817518248175, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI19921000, Length=217, Percent_Identity=30.4147465437788, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24583077, Length=217, Percent_Identity=30.4147465437788, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24583079, Length=217, Percent_Identity=30.4147465437788, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022694
- InterPro:   IPR006180
- InterPro:   IPR006176
- InterPro:   IPR006108
- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00725 3HCDH; PF02737 3HCDH_N [H]

EC number: =1.1.1.157 [H]

Molecular weight: Translated: 31659; Mature: 31528

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: PS00067 3HCDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDQQKTMAVVGAGVIGLSWARLARSHGWRVGITDPRDDLDAVVRAAFGADDSDVFTSHT
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHCCCCCHHHHHHH
LADVVAEADLVQENGPERLAVKRELFGQFLESAPEHAVLATSSSSIGATLIADGLGAGDR
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHCCCCCCCCE
VIVGHPFNPPELMPLVEVVPGTQTSDSTLNAAVDLYRKLGRAPIVIRKEIPGFVANRLQV
EEECCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHH
ALTREAQYLVEEGVVSVTDLDTALQNSLGLRWAATGLFEGNTLGGGPEGARHLYEGLGAE
HHHHHHHHHHHCCCEEEHHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHHHCCC
VGKITMGTPSSDPRVIEKLIEDIDTAYGTGPENYERLLARRNERTRAVLAALRQLDA
CCEEEECCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SDQQKTMAVVGAGVIGLSWARLARSHGWRVGITDPRDDLDAVVRAAFGADDSDVFTSHT
CCHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHCCCCCHHHHHHH
LADVVAEADLVQENGPERLAVKRELFGQFLESAPEHAVLATSSSSIGATLIADGLGAGDR
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHCCCCCCCCE
VIVGHPFNPPELMPLVEVVPGTQTSDSTLNAAVDLYRKLGRAPIVIRKEIPGFVANRLQV
EEECCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHH
ALTREAQYLVEEGVVSVTDLDTALQNSLGLRWAATGLFEGNTLGGGPEGARHLYEGLGAE
HHHHHHHHHHHCCCEEEHHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHHHCCC
VGKITMGTPSSDPRVIEKLIEDIDTAYGTGPENYERLLARRNERTRAVLAALRQLDA
CCEEEECCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA