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The map label for this gene is kshA [H]

Identifier: 169627827

GI number: 169627827

Start: 730405

End: 731403

Strand: Direct

Name: kshA [H]

Synonym: MAB_0726

Alternate gene names: 169627827

Gene position: 730405-731403 (Clockwise)

Preceding gene: 169627823

Following gene: 169627828

Centisome position: 14.41

GC content: 62.66

Gene sequence:

>999_bases
ATGCCGAAGCCGCCGTTGTCGATGAGGCCCACCGGGTGGTTCCAGGTTGCCTGGTCCGCGCAGATCACTGTCGGTGCCGT
GCACCGGATGAGCTATTTCGGCCGCGAGATGGTGGCCTGGCGGGCGCAATCGGGCGAGTTGGCAGTGATGGACGCCCATT
GCGAGCACCTCGGTGCTCACCTGGGCCACGGTGGTCACGTCGAAGGGGACCGCATCGTGTGCCCGTTTCATGGCTGGGAG
TGGAATCGTGACGGCAGGAATGTCTGCATTCCCTACGAGCGGCGGCCAAACCCGTTGCGGCGCATTCGGAGCTACCCGGT
AGTCGAACGCAATGAGGCCGTCTACATCTGGCACGACACCGCCGGGCGTCCGCCGTACTTCGACGTTCCCGACGTCTTCA
CCGGATTCGGCGACGGCGGCAGCGCGCGGGACTACTATCCGGGATACCCGCACAGCACGTTGTATCGCGAACGGCTGCAA
CTACATCCGCAATACGTCCTGGAGAACGGCGTCGATTTCGCGCATTTCAAGTACGTGCACAAGACGCCGTTCATCCCGAG
GTTCACCCGGCAGGAGTTCGGCACGCCGATTTCGTACGTCGACTTCACCATCGCCTTCGATGAGATACCGGGCATGTCCG
CCGAAGACATAAAGAGCGGCGTGCAGGCCATCAACGGGGGTTTGGGTGTCGCCGTCACCAAGAGCTGGGGAATGGTCGAC
AACCGCACGGTCTCCGCAGTGACCCCAGTCGATGACGAGACCTGTGATGTGCGGTTCACCGTCTTCATCGGCAGGCAACC
CGGCGACGATTCGGCCGAGCCGCCGCAGTCCGCGAAGACGTTCGCGCAGGCCATCATCGACCAATTCCTCGCCGATATCC
ACATCTGGTCGCATCAGCGCTATTCGGACCCGCCCGCATTGGTGCGCGCCGAATACGAAGGCTTCATCGCCCTGCGTAAA
TGGGCGACTCAGTTCTATCCGGAGGAGAGCACGGCATGA

Upstream 100 bases:

>100_bases
TCGCTCATCCGGACGATGCTAGCGCGTGCGGGAATTTTTCATAGAAGTCTCTGTGAAAGTTGGTCGGAATGGATTACTGT
CGCCGCTTGAGGAGGTTCCG

Downstream 100 bases:

>100_bases
GCGTAATCAGGGTGTTCCAGGTCGCCACCGGCAACGTCGGCACCGAGATGATCAGGCGCATCGCGTCGCATCCCGACTTG
GAACTGGCCGGATTGCATTG

Product: hypothetical protein

Products: NA

Alternate protein names: Rieske-type oxygenase; RO [H]

Number of amino acids: Translated: 332; Mature: 331

Protein sequence:

>332_residues
MPKPPLSMRPTGWFQVAWSAQITVGAVHRMSYFGREMVAWRAQSGELAVMDAHCEHLGAHLGHGGHVEGDRIVCPFHGWE
WNRDGRNVCIPYERRPNPLRRIRSYPVVERNEAVYIWHDTAGRPPYFDVPDVFTGFGDGGSARDYYPGYPHSTLYRERLQ
LHPQYVLENGVDFAHFKYVHKTPFIPRFTRQEFGTPISYVDFTIAFDEIPGMSAEDIKSGVQAINGGLGVAVTKSWGMVD
NRTVSAVTPVDDETCDVRFTVFIGRQPGDDSAEPPQSAKTFAQAIIDQFLADIHIWSHQRYSDPPALVRAEYEGFIALRK
WATQFYPEESTA

Sequences:

>Translated_332_residues
MPKPPLSMRPTGWFQVAWSAQITVGAVHRMSYFGREMVAWRAQSGELAVMDAHCEHLGAHLGHGGHVEGDRIVCPFHGWE
WNRDGRNVCIPYERRPNPLRRIRSYPVVERNEAVYIWHDTAGRPPYFDVPDVFTGFGDGGSARDYYPGYPHSTLYRERLQ
LHPQYVLENGVDFAHFKYVHKTPFIPRFTRQEFGTPISYVDFTIAFDEIPGMSAEDIKSGVQAINGGLGVAVTKSWGMVD
NRTVSAVTPVDDETCDVRFTVFIGRQPGDDSAEPPQSAKTFAQAIIDQFLADIHIWSHQRYSDPPALVRAEYEGFIALRK
WATQFYPEESTA
>Mature_331_residues
PKPPLSMRPTGWFQVAWSAQITVGAVHRMSYFGREMVAWRAQSGELAVMDAHCEHLGAHLGHGGHVEGDRIVCPFHGWEW
NRDGRNVCIPYERRPNPLRRIRSYPVVERNEAVYIWHDTAGRPPYFDVPDVFTGFGDGGSARDYYPGYPHSTLYRERLQL
HPQYVLENGVDFAHFKYVHKTPFIPRFTRQEFGTPISYVDFTIAFDEIPGMSAEDIKSGVQAINGGLGVAVTKSWGMVDN
RTVSAVTPVDDETCDVRFTVFIGRQPGDDSAEPPQSAKTFAQAIIDQFLADIHIWSHQRYSDPPALVRAEYEGFIALRKW
ATQFYPEESTA

Specific function: Catalyzes the opening of ring B of 1,4-androstadiene- 3,17,-dione (ADD) and 4-androstene-3,17-dione (ADD) with concomitant aromatization of ring A. The ring B is subsequently hydroxylated to yield a catechol and then subject to meta- cleavage [H]

COG id: COG4638

COG function: function code PR; Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Rieske domain [H]

Homologues:

Organism=Caenorhabditis elegans, GI71983709, Length=364, Percent_Identity=27.7472527472527, Blast_Score=117, Evalue=7e-27,
Organism=Drosophila melanogaster, GI161085896, Length=342, Percent_Identity=23.9766081871345, Blast_Score=107, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017941 [H]

Pfam domain/function: PF00355 Rieske [H]

EC number: NA

Molecular weight: Translated: 37638; Mature: 37506

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKPPLSMRPTGWFQVAWSAQITVGAVHRMSYFGREMVAWRAQSGELAVMDAHCEHLGAH
CCCCCCCCCCCCEEEEEEECEEEHHHHHHHHHHHHHHEEEECCCCCEEEEEHHHHHHHHH
LGHGGHVEGDRIVCPFHGWEWNRDGRNVCIPYERRPNPLRRIRSYPVVERNEAVYIWHDT
CCCCCCCCCCEEEECCCCCEECCCCCEEEECCCCCCCHHHHHHCCCCEECCCEEEEEECC
AGRPPYFDVPDVFTGFGDGGSARDYYPGYPHSTLYRERLQLHPQYVLENGVDFAHFKYVH
CCCCCCCCCCHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHCCCCCHHEEEEC
KTPFIPRFTRQEFGTPISYVDFTIAFDEIPGMSAEDIKSGVQAINGGLGVAVTKSWGMVD
CCCCCCCHHHHHHCCCEEEEEEEEEECCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCC
NRTVSAVTPVDDETCDVRFTVFIGRQPGDDSAEPPQSAKTFAQAIIDQFLADIHIWSHQR
CCEEEEECCCCCCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
YSDPPALVRAEYEGFIALRKWATQFYPEESTA
CCCCCCEEEECCCCHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
PKPPLSMRPTGWFQVAWSAQITVGAVHRMSYFGREMVAWRAQSGELAVMDAHCEHLGAH
CCCCCCCCCCCEEEEEEECEEEHHHHHHHHHHHHHHEEEECCCCCEEEEEHHHHHHHHH
LGHGGHVEGDRIVCPFHGWEWNRDGRNVCIPYERRPNPLRRIRSYPVVERNEAVYIWHDT
CCCCCCCCCCEEEECCCCCEECCCCCEEEECCCCCCCHHHHHHCCCCEECCCEEEEEECC
AGRPPYFDVPDVFTGFGDGGSARDYYPGYPHSTLYRERLQLHPQYVLENGVDFAHFKYVH
CCCCCCCCCCHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHCCCCCHHEEEEC
KTPFIPRFTRQEFGTPISYVDFTIAFDEIPGMSAEDIKSGVQAINGGLGVAVTKSWGMVD
CCCCCCCHHHHHHCCCEEEEEEEEEECCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCC
NRTVSAVTPVDDETCDVRFTVFIGRQPGDDSAEPPQSAKTFAQAIIDQFLADIHIWSHQR
CCEEEEECCCCCCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
YSDPPALVRAEYEGFIALRKWATQFYPEESTA
CCCCCCEEEECCCCHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA