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The map label for this gene is amiC [H]

Identifier: 169627825

GI number: 169627825

Start: 728277

End: 729692

Strand: Reverse

Name: amiC [H]

Synonym: MAB_0724c

Alternate gene names: 169627825

Gene position: 729692-728277 (Counterclockwise)

Preceding gene: 169627826

Following gene: 169627824

Centisome position: 14.4

GC content: 66.45

Gene sequence:

>1416_bases
ATGACCCGCATCCACGCGTTTACCGAGGACGCCCTGGGCGACCTGGATGCCACCGGAGTCGCCGAGCGAATCGCCTCCGG
CGAGGTCACTGCCGCCGAATGCGCCGAGGCCGCCATCGTCCGTCTCGAGCGGGTCAACCCGACGCTCAACGCAGTGGAAT
TCAAGGATTTTCCGCGCGCCCGCGAGCGCGCCGAACAGGCAGACGCCGCGTCCAGCACTTCCGGCACTTTTCGGGGTGTG
CCCACCGCGACGAAATGCAATATCCACGTGGCGGGTATGCCACTGACGGAAGGCTCGGCGGCGATCACGCCGGCACCGCA
GACTGACGATGGACCGTTCGCACGACAATTCCTCAGCACCGGCGTGATCCCCATCGCCTCGACGACCATGCCCGAATACG
GCTGGTCTGCCACCACGGAGCGCGCAGGTGGCTCGGCTACCCGCAATCCGTGGCATACGGACTTCTCTGCCGGCGGATCC
TCCGGCGGGTCGGCGGCACTGGTAGCCGCCGGTGTGGTGCCCATCGCACACGGCAATGACGGCGGCGGCTCGATCCGGAT
CCCCGCGGCGGCCTGCGGACTCGTCGGCCTCAAGCCGAGCCGCGGAAGGCTTTTGGGCGACCCGTCGAGCAGTTCGGCCC
CAGTGAAAATCGTCGCCGAGGGGGTGCTGGTGCGCAGTGTGCGGGACTGTGCCCGCTTCTTCGAGTCGGCCGAACTGCAC
TATCGCAACCCAAAGTTGACACCGATCGGGCACGTGGATCGCCCGGTCCAGCGCCGGCTGCGCATCGGCCTATGCATGGA
TTCCCCCTTCACTCCCGCCACCGACAACCCAACCCGGCAGGCAGTGAACTCCGCCGCGGAATTGCTTGAATCCCTTGGCC
ACACCGTCGAACCGTACACACCCGCCGTGCTTCCGTCGTTCAAGATCGACTTCGAGGACTACTGGGCCTTCTTGGCCTTC
GCCGTGGCTAAGGGTGGTCCCCGGCTGTTCGAGGGGTTCGACCCCGCTAAGTTGGACCGGCTGACCCTCGGGCTCAGCCG
CAGATTCGTCAGGCGCTCGTACCGCACGCCGCTCTTCTTGGCACGCCTGGCCGCCGCCGCCCGGGTATACGAACGCGGCT
TCACCACCGGTATCGATGCGGTGCTCACGCCCGTGCTCACCCACACCACGCCACGCATCGGGTATCTCACCCCGGACCAG
GATCCCGACGTACTGCTGGACAAGCTCAGCTCGTACGTGGGATTCACTCCGGTGCACAACGCCTCCGGTGCGCCAGCGAT
ATCGCTGCCGCTCGGCCAAGACCCCGACGGCCTGCCCATCGGAGTGATGTTCAGCGGCCGCCGAGGCAGTGAACGAACGT
TGCTCGAGCTGGCGATGGAAATCGAGGAGGCACAGCCCTTCTCGATACTGGGCTGA

Upstream 100 bases:

>100_bases
GAGGGCTTGTTTCCGAAAAACAGCTGGGTACCTATTCGGATCTCGAGGAGGCCCGTCGCGGGCTGACCAACGCGATCGTC
GCTTACCTAGGAGGTCACGA

Downstream 100 bases:

>100_bases
TGCGTGGCCGTGACTCCAATCACAAACCACCAGTGTTACAACAAAATTAGAGCGCTCGACATGCGATCCACAGTTTGAGC
ACTTACCGTCTAATTCATGC

Product: amidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 471; Mature: 470

Protein sequence:

>471_residues
MTRIHAFTEDALGDLDATGVAERIASGEVTAAECAEAAIVRLERVNPTLNAVEFKDFPRARERAEQADAASSTSGTFRGV
PTATKCNIHVAGMPLTEGSAAITPAPQTDDGPFARQFLSTGVIPIASTTMPEYGWSATTERAGGSATRNPWHTDFSAGGS
SGGSAALVAAGVVPIAHGNDGGGSIRIPAAACGLVGLKPSRGRLLGDPSSSSAPVKIVAEGVLVRSVRDCARFFESAELH
YRNPKLTPIGHVDRPVQRRLRIGLCMDSPFTPATDNPTRQAVNSAAELLESLGHTVEPYTPAVLPSFKIDFEDYWAFLAF
AVAKGGPRLFEGFDPAKLDRLTLGLSRRFVRRSYRTPLFLARLAAAARVYERGFTTGIDAVLTPVLTHTTPRIGYLTPDQ
DPDVLLDKLSSYVGFTPVHNASGAPAISLPLGQDPDGLPIGVMFSGRRGSERTLLELAMEIEEAQPFSILG

Sequences:

>Translated_471_residues
MTRIHAFTEDALGDLDATGVAERIASGEVTAAECAEAAIVRLERVNPTLNAVEFKDFPRARERAEQADAASSTSGTFRGV
PTATKCNIHVAGMPLTEGSAAITPAPQTDDGPFARQFLSTGVIPIASTTMPEYGWSATTERAGGSATRNPWHTDFSAGGS
SGGSAALVAAGVVPIAHGNDGGGSIRIPAAACGLVGLKPSRGRLLGDPSSSSAPVKIVAEGVLVRSVRDCARFFESAELH
YRNPKLTPIGHVDRPVQRRLRIGLCMDSPFTPATDNPTRQAVNSAAELLESLGHTVEPYTPAVLPSFKIDFEDYWAFLAF
AVAKGGPRLFEGFDPAKLDRLTLGLSRRFVRRSYRTPLFLARLAAAARVYERGFTTGIDAVLTPVLTHTTPRIGYLTPDQ
DPDVLLDKLSSYVGFTPVHNASGAPAISLPLGQDPDGLPIGVMFSGRRGSERTLLELAMEIEEAQPFSILG
>Mature_470_residues
TRIHAFTEDALGDLDATGVAERIASGEVTAAECAEAAIVRLERVNPTLNAVEFKDFPRARERAEQADAASSTSGTFRGVP
TATKCNIHVAGMPLTEGSAAITPAPQTDDGPFARQFLSTGVIPIASTTMPEYGWSATTERAGGSATRNPWHTDFSAGGSS
GGSAALVAAGVVPIAHGNDGGGSIRIPAAACGLVGLKPSRGRLLGDPSSSSAPVKIVAEGVLVRSVRDCARFFESAELHY
RNPKLTPIGHVDRPVQRRLRIGLCMDSPFTPATDNPTRQAVNSAAELLESLGHTVEPYTPAVLPSFKIDFEDYWAFLAFA
VAKGGPRLFEGFDPAKLDRLTLGLSRRFVRRSYRTPLFLARLAAAARVYERGFTTGIDAVLTPVLTHTTPRIGYLTPDQD
PDVLLDKLSSYVGFTPVHNASGAPAISLPLGQDPDGLPIGVMFSGRRGSERTLLELAMEIEEAQPFSILG

Specific function: Unknown

COG id: COG0154

COG function: function code J; Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amidase family [H]

Homologues:

Organism=Homo sapiens, GI222831590, Length=515, Percent_Identity=24.2718446601942, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI195972892, Length=221, Percent_Identity=28.5067873303167, Blast_Score=81, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17538252, Length=312, Percent_Identity=30.4487179487179, Blast_Score=113, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17556264, Length=300, Percent_Identity=28, Blast_Score=98, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71990152, Length=298, Percent_Identity=28.8590604026846, Blast_Score=86, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17556276, Length=303, Percent_Identity=29.3729372937294, Blast_Score=86, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17556278, Length=303, Percent_Identity=29.3729372937294, Blast_Score=85, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17543272, Length=338, Percent_Identity=26.3313609467456, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17537465, Length=205, Percent_Identity=31.7073170731707, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI32565337, Length=238, Percent_Identity=29.8319327731092, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17538254, Length=306, Percent_Identity=25.8169934640523, Blast_Score=72, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6319685, Length=398, Percent_Identity=25.1256281407035, Blast_Score=64, Evalue=6e-11,
Organism=Drosophila melanogaster, GI21356731, Length=480, Percent_Identity=27.0833333333333, Blast_Score=104, Evalue=2e-22,
Organism=Drosophila melanogaster, GI161078093, Length=496, Percent_Identity=25.6048387096774, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24644968, Length=195, Percent_Identity=31.7948717948718, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI45550774, Length=199, Percent_Identity=31.1557788944724, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24648435, Length=199, Percent_Identity=31.1557788944724, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24648437, Length=199, Percent_Identity=31.1557788944724, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24652985, Length=203, Percent_Identity=33.4975369458128, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI19922090, Length=203, Percent_Identity=33.4975369458128, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24652981, Length=203, Percent_Identity=33.4975369458128, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24652983, Length=203, Percent_Identity=33.4975369458128, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24648441, Length=122, Percent_Identity=35.2459016393443, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24648439, Length=122, Percent_Identity=35.2459016393443, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000120
- InterPro:   IPR020556 [H]

Pfam domain/function: PF01425 Amidase [H]

EC number: =3.5.1.4 [H]

Molecular weight: Translated: 49934; Mature: 49803

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: PS00571 AMIDASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRIHAFTEDALGDLDATGVAERIASGEVTAAECAEAAIVRLERVNPTLNAVEFKDFPRA
CCEEECCCHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCEEECCCCHHH
RERAEQADAASSTSGTFRGVPTATKCNIHVAGMPLTEGSAAITPAPQTDDGPFARQFLST
HHHHHHHHCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCEECCCCCCCCCHHHHHHHHC
GVIPIASTTMPEYGWSATTERAGGSATRNPWHTDFSAGGSSGGSAALVAAGVVPIAHGND
CCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECEEEEECCCC
GGGSIRIPAAACGLVGLKPSRGRLLGDPSSSSAPVKIVAEGVLVRSVRDCARFFESAELH
CCCEEEECHHHCCCCCCCCCCCCEECCCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCEE
YRNPKLTPIGHVDRPVQRRLRIGLCMDSPFTPATDNPTRQAVNSAAELLESLGHTVEPYT
ECCCCCCCCCCCCHHHHHHHHEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCC
PAVLPSFKIDFEDYWAFLAFAVAKGGPRLFEGFDPAKLDRLTLGLSRRFVRRSYRTPLFL
CCCCCCEEECHHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHH
ARLAAAARVYERGFTTGIDAVLTPVLTHTTPRIGYLTPDQDPDVLLDKLSSYVGFTPVHN
HHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHCCCCCCCC
ASGAPAISLPLGQDPDGLPIGVMFSGRRGSERTLLELAMEIEEAQPFSILG
CCCCCEEECCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
TRIHAFTEDALGDLDATGVAERIASGEVTAAECAEAAIVRLERVNPTLNAVEFKDFPRA
CEEECCCHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCEEECCCCHHH
RERAEQADAASSTSGTFRGVPTATKCNIHVAGMPLTEGSAAITPAPQTDDGPFARQFLST
HHHHHHHHCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCEECCCCCCCCCHHHHHHHHC
GVIPIASTTMPEYGWSATTERAGGSATRNPWHTDFSAGGSSGGSAALVAAGVVPIAHGND
CCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECEEEEECCCC
GGGSIRIPAAACGLVGLKPSRGRLLGDPSSSSAPVKIVAEGVLVRSVRDCARFFESAELH
CCCEEEECHHHCCCCCCCCCCCCEECCCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCEE
YRNPKLTPIGHVDRPVQRRLRIGLCMDSPFTPATDNPTRQAVNSAAELLESLGHTVEPYT
ECCCCCCCCCCCCHHHHHHHHEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCC
PAVLPSFKIDFEDYWAFLAFAVAKGGPRLFEGFDPAKLDRLTLGLSRRFVRRSYRTPLFL
CCCCCCEEECHHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHH
ARLAAAARVYERGFTTGIDAVLTPVLTHTTPRIGYLTPDQDPDVLLDKLSSYVGFTPVHN
HHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHCCCCCCCC
ASGAPAISLPLGQDPDGLPIGVMFSGRRGSERTLLELAMEIEEAQPFSILG
CCCCCEEECCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]