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The map label for this gene is 169627797

Identifier: 169627797

GI number: 169627797

Start: 698065

End: 699723

Strand: Direct

Name: 169627797

Synonym: MAB_0695

Alternate gene names: NA

Gene position: 698065-699723 (Clockwise)

Preceding gene: 169627796

Following gene: 169627799

Centisome position: 13.78

GC content: 65.04

Gene sequence:

>1659_bases
GTGGGTGACACGAGTACCGATGTCATTGTCGTGGGCGCGGGACTGGCCGGGTTGGTGGCGGCCTGCGAATTGGTGGATCG
CGGCAAAAGAGTCGTCATCGTCGAACAGGAAAACGCCGCCAATCTAGGTGGGCAGGCGTATTGGTCTTTTGGCGGTCTGT
TCTTTGTCAACAGTCCCGAACAGCGCCGCTTGGGAATCAAGGATTCCCACGAATTGGCCCTGCAGGACTGGCTCGGTACC
GCCGGATTTGACCGCCCGGAGGATCATTGGCCGCGTCAATGGGCGCACGCGTACGTGGATTTTGCCGCAGGGGAAAAGCG
AAGCTGGTTGCGGGCCAGGGGGTTACAGACCTTTCCCGTCGTGGCATGGGCTGAACGCGGCGGCAAGGATGCCTTGGGGC
CGGGAAACTCGGTGCCGCGATTCCATATCACGTGGGGCACGGGCCCTGGGCTGGTGGAGATCTTCGCCCGGCGCGTGCTC
GCCGCGGTGGATCGCGGTCAGGTACGCATCGCCTACCGCCACCAGGTCGACGAATTGGTGGTCGATCAGGGTGCCGTCGT
GGGTGTGCGGGGGACGGTGTTGGAGCCTTCGACGGCCGCGCGCGGTATCGCGTCATCACGAATTAAATTGGGGGAGTTTG
AGTTCCGTGCGCAGGCCGTCATCGTTACCAGCGGGGGCATTGGTGGAAACCACGACCTAGTGCGGGAAAATTGGCCCGAG
CGGCTGGGTCGGGTGCCGTCACAGTTGTTGACGGGCGTACCCGCCCACGTTGATGGCCGCATGCTGGGGATTTCGGTGGC
CGCCGGGGCTCACCTGATCAACCGTGACCGCATGTGGCACTACACCGAAGGCATCACCAACCACAACCCGATCTGGCCGG
GCCATGGGATCCGCATCTTGCCCGGCCCTTCTTCACTCTGGTTGGATGCCAACGGATCTCGAATACCTGCTCCGTTGTTC
CCCGGATTCGACACCCTGGGCACGCTCGAGCACATCTGTCGCAGCGGGCAGGACTATTCCTGGTTCATACTCAACGCGCG
GATCATCGCCAAGGAGTTCGCACTGTCGGGGCAGGAACAGAACCCCGACCTCACGGGCAAGGATGTGCGTGGGGTGCTGC
GGCGGGGCAAGGCGGGCGCGCCCGCGCCGGTACAGGCGTTCGTCGACAACGGCGTCGACTTCGTCACCGCCACCAATCTG
CCCGACCTGGTGGCCAAGATGAACGCGTTGCCGGACGTCAGCCCCCTGGACTACGCGACCATCGCTCAGCAGGTGACGGC
GCGTGATCGTGAGGTGGCGAACCCGTTCGGCAAGGACCCACAGATCGCGGCGATCCGTGCCGCCCGTGCGTACCTCGCCG
ATCGCGTAGCCCGCGTGGTGGCGCCGCACCGGCTCACCGACCCCAAGGCCGGCCCGCTCATCGCTGTGAAGCTTCACATC
CTCACCCGAAAGACATTGGGCGGATTGGAGACCGACCTTGACTCACGCGTCCTGCGCGCCGACGGCAGCTGCTTCGAAGG
TCTCTATGCGGCGGGAGAGGTTGCCGGATTCGGTGGTGGCGGTGTGCATGGCTACCGGGCGCTGGAGGGCACCTTCCTGG
GTGGCTGCATCTTCAGCGGACGGGCCGCGGGCCGGGGCGCCGCCGAGGACATCGGCTAG

Upstream 100 bases:

>100_bases
CGCCGAGACCGGTCGAGGGGCATAACGGCCAGTGCTTTGTGCTTTCACCGCAAGGAAGTTGGACCTTTTATTCGGCAATC
GTGCCCGCTACGGTGAACCG

Downstream 100 bases:

>100_bases
AAGGTGACCGCGTCCTCCTGCGGCAGCACCTGGAAATCGGCATCGGACATCTCCCGAAAACGCGTGTAGTAGAACGGGTA
TGCGGCCTCTTGCAGGATGC

Product: putative FAD-binding dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 552; Mature: 551

Protein sequence:

>552_residues
MGDTSTDVIVVGAGLAGLVAACELVDRGKRVVIVEQENAANLGGQAYWSFGGLFFVNSPEQRRLGIKDSHELALQDWLGT
AGFDRPEDHWPRQWAHAYVDFAAGEKRSWLRARGLQTFPVVAWAERGGKDALGPGNSVPRFHITWGTGPGLVEIFARRVL
AAVDRGQVRIAYRHQVDELVVDQGAVVGVRGTVLEPSTAARGIASSRIKLGEFEFRAQAVIVTSGGIGGNHDLVRENWPE
RLGRVPSQLLTGVPAHVDGRMLGISVAAGAHLINRDRMWHYTEGITNHNPIWPGHGIRILPGPSSLWLDANGSRIPAPLF
PGFDTLGTLEHICRSGQDYSWFILNARIIAKEFALSGQEQNPDLTGKDVRGVLRRGKAGAPAPVQAFVDNGVDFVTATNL
PDLVAKMNALPDVSPLDYATIAQQVTARDREVANPFGKDPQIAAIRAARAYLADRVARVVAPHRLTDPKAGPLIAVKLHI
LTRKTLGGLETDLDSRVLRADGSCFEGLYAAGEVAGFGGGGVHGYRALEGTFLGGCIFSGRAAGRGAAEDIG

Sequences:

>Translated_552_residues
MGDTSTDVIVVGAGLAGLVAACELVDRGKRVVIVEQENAANLGGQAYWSFGGLFFVNSPEQRRLGIKDSHELALQDWLGT
AGFDRPEDHWPRQWAHAYVDFAAGEKRSWLRARGLQTFPVVAWAERGGKDALGPGNSVPRFHITWGTGPGLVEIFARRVL
AAVDRGQVRIAYRHQVDELVVDQGAVVGVRGTVLEPSTAARGIASSRIKLGEFEFRAQAVIVTSGGIGGNHDLVRENWPE
RLGRVPSQLLTGVPAHVDGRMLGISVAAGAHLINRDRMWHYTEGITNHNPIWPGHGIRILPGPSSLWLDANGSRIPAPLF
PGFDTLGTLEHICRSGQDYSWFILNARIIAKEFALSGQEQNPDLTGKDVRGVLRRGKAGAPAPVQAFVDNGVDFVTATNL
PDLVAKMNALPDVSPLDYATIAQQVTARDREVANPFGKDPQIAAIRAARAYLADRVARVVAPHRLTDPKAGPLIAVKLHI
LTRKTLGGLETDLDSRVLRADGSCFEGLYAAGEVAGFGGGGVHGYRALEGTFLGGCIFSGRAAGRGAAEDIG
>Mature_551_residues
GDTSTDVIVVGAGLAGLVAACELVDRGKRVVIVEQENAANLGGQAYWSFGGLFFVNSPEQRRLGIKDSHELALQDWLGTA
GFDRPEDHWPRQWAHAYVDFAAGEKRSWLRARGLQTFPVVAWAERGGKDALGPGNSVPRFHITWGTGPGLVEIFARRVLA
AVDRGQVRIAYRHQVDELVVDQGAVVGVRGTVLEPSTAARGIASSRIKLGEFEFRAQAVIVTSGGIGGNHDLVRENWPER
LGRVPSQLLTGVPAHVDGRMLGISVAAGAHLINRDRMWHYTEGITNHNPIWPGHGIRILPGPSSLWLDANGSRIPAPLFP
GFDTLGTLEHICRSGQDYSWFILNARIIAKEFALSGQEQNPDLTGKDVRGVLRRGKAGAPAPVQAFVDNGVDFVTATNLP
DLVAKMNALPDVSPLDYATIAQQVTARDREVANPFGKDPQIAAIRAARAYLADRVARVVAPHRLTDPKAGPLIAVKLHIL
TRKTLGGLETDLDSRVLRADGSCFEGLYAAGEVAGFGGGGVHGYRALEGTFLGGCIFSGRAAGRGAAEDIG

Specific function: Able to catalyze the elimination of the C-1 and C-2 hydrogen atoms of the A-ring from the polycyclic ring structure of 3-ketosteroids, but the ketosteroid dehydrogenase activity is low compared to KsdD in the cholesterol degradation process. The low activ

COG id: COG3573

COG function: function code R; Predicted oxidoreductase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent oxidoreductase 2 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 59131; Mature: 59000

Theoretical pI: Translated: 8.06; Mature: 8.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGDTSTDVIVVGAGLAGLVAACELVDRGKRVVIVEQENAANLGGQAYWSFGGLFFVNSPE
CCCCCCCEEEECCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCEEEEECCCEEEECCCH
QRRLGIKDSHELALQDWLGTAGFDRPEDHWPRQWAHAYVDFAAGEKRSWLRARGLQTFPV
HHCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHCCCCCCCE
VAWAERGGKDALGPGNSVPRFHITWGTGPGLVEIFARRVLAAVDRGQVRIAYRHQVDELV
EEECCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHH
VDQGAVVGVRGTVLEPSTAARGIASSRIKLGEFEFRAQAVIVTSGGIGGNHDLVRENWPE
HCCCCEEEEECEEECCCHHHCCHHHCCEEECCEEEEEEEEEEEECCCCCCCCHHHHHHHH
RLGRVPSQLLTGVPAHVDGRMLGISVAAGAHLINRDRMWHYTEGITNHNPIWPGHGIRIL
HHHCCHHHHHCCCCCCCCCEEEEEEEECCCHHHCCCCCEEECCCCCCCCCCCCCCCEEEE
PGPSSLWLDANGSRIPAPLFPGFDTLGTLEHICRSGQDYSWFILNARIIAKEFALSGQEQ
ECCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHCCCCCC
NPDLTGKDVRGVLRRGKAGAPAPVQAFVDNGVDFVTATNLPDLVAKMNALPDVSPLDYAT
CCCCCCHHHHHHHHCCCCCCCCHHHHHHCCCCCEEEECCCHHHHHHHHCCCCCCCCCHHH
IAQQVTARDREVANPFGKDPQIAAIRAARAYLADRVARVVAPHRLTDPKAGPLIAVKLHI
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEE
LTRKTLGGLETDLDSRVLRADGSCFEGLYAAGEVAGFGGGGVHGYRALEGTFLGGCIFSG
EHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCEEECCCEEEEEEECC
RAAGRGAAEDIG
CCCCCCCCCCCC
>Mature Secondary Structure 
GDTSTDVIVVGAGLAGLVAACELVDRGKRVVIVEQENAANLGGQAYWSFGGLFFVNSPE
CCCCCCEEEECCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCEEEEECCCEEEECCCH
QRRLGIKDSHELALQDWLGTAGFDRPEDHWPRQWAHAYVDFAAGEKRSWLRARGLQTFPV
HHCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHCCCCCCCE
VAWAERGGKDALGPGNSVPRFHITWGTGPGLVEIFARRVLAAVDRGQVRIAYRHQVDELV
EEECCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHH
VDQGAVVGVRGTVLEPSTAARGIASSRIKLGEFEFRAQAVIVTSGGIGGNHDLVRENWPE
HCCCCEEEEECEEECCCHHHCCHHHCCEEECCEEEEEEEEEEEECCCCCCCCHHHHHHHH
RLGRVPSQLLTGVPAHVDGRMLGISVAAGAHLINRDRMWHYTEGITNHNPIWPGHGIRIL
HHHCCHHHHHCCCCCCCCCEEEEEEEECCCHHHCCCCCEEECCCCCCCCCCCCCCCEEEE
PGPSSLWLDANGSRIPAPLFPGFDTLGTLEHICRSGQDYSWFILNARIIAKEFALSGQEQ
ECCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHCCCCCC
NPDLTGKDVRGVLRRGKAGAPAPVQAFVDNGVDFVTATNLPDLVAKMNALPDVSPLDYAT
CCCCCCHHHHHHHHCCCCCCCCHHHHHHCCCCCEEEECCCHHHHHHHHCCCCCCCCCHHH
IAQQVTARDREVANPFGKDPQIAAIRAARAYLADRVARVVAPHRLTDPKAGPLIAVKLHI
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEE
LTRKTLGGLETDLDSRVLRADGSCFEGLYAAGEVAGFGGGGVHGYRALEGTFLGGCIFSG
EHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCEEECCCEEEEEEECC
RAAGRGAAEDIG
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA