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The map label for this gene is nagD [H]

Identifier: 169627744

GI number: 169627744

Start: 643391

End: 644188

Strand: Direct

Name: nagD [H]

Synonym: MAB_0641

Alternate gene names: 169627744

Gene position: 643391-644188 (Clockwise)

Preceding gene: 169627733

Following gene: 169627745

Centisome position: 12.7

GC content: 65.66

Gene sequence:

>798_bases
ATGACCGTCGGCGGAGTGCTCTTCGATATCGACGGGGTCCTGGTGACCTCGTGGGAGCCGATCGACGGCGCCGCGCAGGC
TCTCAAGGCACTCGAGAACGACGACATTCGCCGATGTTTCCTGACCAACACCACGTCGCGGACCCGTGTGCAGATCGCCG
AGTTGCTCAGCGCCGCCGGGCTGGCGGTGCCCGCCGACGAGGTGATCACCGCGGCGATGTTGACCGCCGATCACGTGATC
ACCCAGCATCCGGGCGCTCGGTGTTACCTGCTGAACGACGGCGACATCACCGCCGACATGGCAGGCGTCGATTTTGTCGA
ATCCCTCTCCGACGATCCCGATGTGATCATTCTGGGCGGAGCAGGCCCGCAGTTCGACCATGTGGCGTTGAGCCGGGTGT
ACGAATTGATGGCCCAGGGCATTCCCGTCGTCGCGATGCACCGTAACGCGGTGTGGAGTACCCGCGAGGGACTGCGCGTC
GACACCGGCGTGTATCTGGCCGGTATGGAACAGGTGTCCGGCCGCAAGGCCGTGGCCGTCGGTAAACCGGCTCCCGCGGG
ATTCCAGCTCGCCGCCGAACGCATGGGCTGCGAGCCGGATCAGGTGGTGATGGTGGGCGACGATCTACATGTCGACGTGC
TGGCCGCTCAGGTTGTCGGGATGACGGGGGTGCTGGTGCGCACCGGCAAATTCCGTCAGGACACCCTGGACCGGTGGGCC
GCCGATCAGTACGCGATGCAGCCGGCCTACGTGGTCGACTCGGTCGCCGATTTGCCGCCCCTGCTGTCGGGCCTATAA

Upstream 100 bases:

>100_bases
AATGCCGAGCGCATACCGCACGCAGGGGTTTTCGCCGAGTTGTGTGCGCCCGGCATGCCCTCGACGTGCGGTGGCGACAC
CATCGCGGGAAAATAGCGCC

Downstream 100 bases:

>100_bases
GCCAGAATCGCCGTCATGATCGATCATTTCGGTATCAACTGTGCGGATCTGCCGGCCGCAGCGGCCTTCTATGACAAGGT
TCTCGGGGTTCTGGGTTTCA

Product: HAD-superfamily hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 265; Mature: 264

Protein sequence:

>265_residues
MTVGGVLFDIDGVLVTSWEPIDGAAQALKALENDDIRRCFLTNTTSRTRVQIAELLSAAGLAVPADEVITAAMLTADHVI
TQHPGARCYLLNDGDITADMAGVDFVESLSDDPDVIILGGAGPQFDHVALSRVYELMAQGIPVVAMHRNAVWSTREGLRV
DTGVYLAGMEQVSGRKAVAVGKPAPAGFQLAAERMGCEPDQVVMVGDDLHVDVLAAQVVGMTGVLVRTGKFRQDTLDRWA
ADQYAMQPAYVVDSVADLPPLLSGL

Sequences:

>Translated_265_residues
MTVGGVLFDIDGVLVTSWEPIDGAAQALKALENDDIRRCFLTNTTSRTRVQIAELLSAAGLAVPADEVITAAMLTADHVI
TQHPGARCYLLNDGDITADMAGVDFVESLSDDPDVIILGGAGPQFDHVALSRVYELMAQGIPVVAMHRNAVWSTREGLRV
DTGVYLAGMEQVSGRKAVAVGKPAPAGFQLAAERMGCEPDQVVMVGDDLHVDVLAAQVVGMTGVLVRTGKFRQDTLDRWA
ADQYAMQPAYVVDSVADLPPLLSGL
>Mature_264_residues
TVGGVLFDIDGVLVTSWEPIDGAAQALKALENDDIRRCFLTNTTSRTRVQIAELLSAAGLAVPADEVITAAMLTADHVIT
QHPGARCYLLNDGDITADMAGVDFVESLSDDPDVIILGGAGPQFDHVALSRVYELMAQGIPVVAMHRNAVWSTREGLRVD
TGVYLAGMEQVSGRKAVAVGKPAPAGFQLAAERMGCEPDQVVMVGDDLHVDVLAAQVVGMTGVLVRTGKFRQDTLDRWAA
DQYAMQPAYVVDSVADLPPLLSGL

Specific function: Unknown

COG id: COG0647

COG function: function code G; Predicted sugar phosphatases of the HAD superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI14149777, Length=246, Percent_Identity=32.1138211382114, Blast_Score=132, Evalue=3e-31,
Organism=Homo sapiens, GI269847098, Length=236, Percent_Identity=31.3559322033898, Blast_Score=108, Evalue=4e-24,
Organism=Homo sapiens, GI10092677, Length=275, Percent_Identity=30.1818181818182, Blast_Score=99, Evalue=3e-21,
Organism=Homo sapiens, GI108796653, Length=291, Percent_Identity=27.4914089347079, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI269847104, Length=205, Percent_Identity=27.3170731707317, Blast_Score=77, Evalue=1e-14,
Organism=Escherichia coli, GI1786890, Length=259, Percent_Identity=29.3436293436293, Blast_Score=108, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17562356, Length=233, Percent_Identity=29.1845493562232, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17557870, Length=241, Percent_Identity=28.6307053941909, Blast_Score=97, Evalue=8e-21,
Organism=Drosophila melanogaster, GI19920940, Length=237, Percent_Identity=29.957805907173, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24666137, Length=293, Percent_Identity=23.5494880546075, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24656330, Length=288, Percent_Identity=22.9166666666667, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006357
- InterPro:   IPR023215 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: NA

Molecular weight: Translated: 28128; Mature: 27997

Theoretical pI: Translated: 4.25; Mature: 4.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVGGVLFDIDGVLVTSWEPIDGAAQALKALENDDIRRCFLTNTTSRTRVQIAELLSAAG
CCCCCEEEEECCEEEECCCCCCHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHCC
LAVPADEVITAAMLTADHVITQHPGARCYLLNDGDITADMAGVDFVESLSDDPDVIILGG
CCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCEEEHHHHHHHHHHCCCCCCEEEECC
AGPQFDHVALSRVYELMAQGIPVVAMHRNAVWSTREGLRVDTGVYLAGMEQVSGRKAVAV
CCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCEECCCEEEECHHHHCCCEEEEE
GKPAPAGFQLAAERMGCEPDQVVMVGDDLHVDVLAAQVVGMTGVLVRTGKFRQDTLDRWA
CCCCCCCHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHEEEEECCCCHHHHHHHHH
ADQYAMQPAYVVDSVADLPPLLSGL
HHHHHCCCHHHHHHHHHCCHHHHCC
>Mature Secondary Structure 
TVGGVLFDIDGVLVTSWEPIDGAAQALKALENDDIRRCFLTNTTSRTRVQIAELLSAAG
CCCCEEEEECCEEEECCCCCCHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHCC
LAVPADEVITAAMLTADHVITQHPGARCYLLNDGDITADMAGVDFVESLSDDPDVIILGG
CCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCEEEHHHHHHHHHHCCCCCCEEEECC
AGPQFDHVALSRVYELMAQGIPVVAMHRNAVWSTREGLRVDTGVYLAGMEQVSGRKAVAV
CCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCEECCCEEEECHHHHCCCEEEEE
GKPAPAGFQLAAERMGCEPDQVVMVGDDLHVDVLAAQVVGMTGVLVRTGKFRQDTLDRWA
CCCCCCCHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHEEEEECCCCHHHHHHHHH
ADQYAMQPAYVVDSVADLPPLLSGL
HHHHHCCCHHHHHHHHHCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]