BacMap

Definition	Mycobacterium abscessus ATCC 19977 chromosome chromosome 1, complete sequence.
Accession	NC_010397
Length	5,067,172

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The map label for this gene is hflB [C]

Identifier: 169627740

GI number: 169627740

Start: 638217

End: 640403

Strand: Reverse

Name: hflB [C]

Synonym: MAB_0637c

Alternate gene names: 169627740

Gene position: 640403-638217 (Counterclockwise)

Preceding gene: 169627741

Following gene: 169627739

Centisome position: 12.64

GC content: 67.08

Gene sequence:

>2187_bases
ATGAGTTCCCTCACCCTCACCGCGCGCCTGAACACCTCGGCCGTCGACTCACGACGCGGTGTGGTCCGGCTGCATCCGGA
AGCAATTGCCGCCCTAGGCATCCGGGAATGGGATGCGATTTCTCTGACAGGGTCGCGTACCACGGCCGCGGTGGTCGGAG
TCGCCCCGCGCTCGGTTCCCGCCGGGACAGCCCTGCTCGACGATGTCACCCTGTCCAACGCGGGCCTGCGCGAGGACGCC
TCGGTGATCGTCGCGGCGGTCACGGTGTATGGCGCACGATCGATCACCGTCAGTGGTTCCTCGATCGCCACCCAGTCGGT
TTCGTCCGCGACGCTCCGCATGGCCCTCTTGGGCAAGGTGATGACCGTCGGTGACACGGTTTCGCTGCTACCCCGAGACC
TCGGGCCCGGCACCTCCACATCGGAGGCGACGTCGGCGCTGACCCGCTCGGTGGGCATCACCTGGACCTCCGAGCTACTC
ACGGTGACGGCGGTCGATCCCGACGGCCCGGTCAGTGTGCAGCCCAATTCGCTTGTCAGCTGGCAGGGTTCGACGGCAAC
CAGCGCCACCTCGGCGACCGCAGCGCGGCAAACGGAGCTCGCACCGGCGGCCGGTCCAGCTCCGGCGGCTTCCACGGTGA
TATCCGTGGAAGATCTCAAGGGCTCTCAGGCGCAAGCCACTCGTCTCACCGAATGGCTCAAACTAGCGCTCGATGAGCCA
GAATTACTCAAAACACTTGGTGCCCAACCGAATCTTGGCGTACTGATATCCGGACCAGCCGGAGTGGGTAAGGCAACGCT
GGCGCGAGCCGTCTGCGCTGCACGCACGCTCATCGAATTGGACGGGCCGGAGGCTGGAGCCACGAGCGCCGACGGACGGC
TCGACATGATCCGCGAGGCGGTAAGCAGGGTGCGGCAATCCGGGGGTGTGCTGCTGATATCCGATATCGATGCATTACTG
CCCGCCGCCGCCGAGCCCGTCGCAACGCTCATCCTTGCCGAATTACGCACTGCGGTAGCCACTTCCGGTGTGGCCTTCAT
CGCAACCACCGCACATCCCGATGCGCTCGACGCACGGCTGCGTGGCCCCGAGCTGTGCGATCGCGAGCTCGGTCTGAGCC
TGCCGGACGCCGCCACCCGCAAATCGCTCCTTGAGGTGCTGTTGGCCAAGGTGCCATCGCAAAACCTACAGCTCGACGAG
ATTGCCTCACGCACGCCCGGTTTTGTCGTAGCCGATCTGGCAGCATTGGTACGAGAGGCGGCGCTGCGCGCGGCCGCGCG
CGCCAGCGAGAAGGCCAGTGCCCCAGCGCTCGCCCAGGAGGATCTGATCGGCGCGCTGTCGGTGATCCGCCCGCTCTCCC
GCTCGACCACCGAAGAGGTCGCCGTAGGGTCGATCACCCTCGACGATGTCGGCGATATGGTCGCCACCAAACAAGCTCTG
ACAGAAGCCGTGCTGTGGCCTCTGCAGCATCCGGACACCTTTCAACGGCTCGGCGTCGACCCGCCCCGGGGTGTTCTGCT
CTACGGGCCGCCCGGCTGCGGCAAGACGTTCGTGGTGCGCGCGCTGGCCAGCTCCGGGCGGCTCTCGGTGCATGCCGTCA
AGGGTGCCGAGCTGATGGACAAATGGGTGGGGTCATCCGAGCAGGCGGTGCGCGATCTGTTTCGACGAGCACGCGATTCG
GCACCGTCCCTGGTGTTCCTCGACGAGGTGGACGCGCTGGCACCGCGCCGCGGGCAAAGCTTCGATTCCGGAGTCACCGA
CCGGGTCGTTGCCGCCCTGCTCACCGAGCTCGACGGGGTGGAACCGTTGCGCGATGTCGTGGTGCTCGGCGCCACCAACC
GGCCAGAACTCATCGACCCCGCGCTACTCCGGCCCGGCCGGATGGAGCGGCTGGTATTCGTCGAGCCCCCGGATGCTCAG
GCCCGCACGGACATCCTCAGGACCGCGGCTCGCTCGGTTCCGCTGGGTGCGGATGTCGATCTGAATGCGCTCGCCGCCGA
CCTCGACGGTTTTTCCGCCGCGGACTGCGCAGCGTTGTTACGCGAGGCCGCCATGGCTGCGATGCGGCGATCCATCGACG
CCGCCGACGTCACCTCCGCGGATATCCACACCGCGCGCTCCGTCGTGCGTCCGTCGCTGGATCCGGTGCAGGTGGCATCA
CTGCGCGCGTTTGCTGACAACCGCTGA

Upstream 100 bases:

>100_bases
GCGCGACCAGCGCCGCGCCTTCCGGCAGGCAGCACTTCCCAAGCGGCGCACCGCCGAGCGCCTGGGCCTGCGCCGCCCCG
GCAGACCGCGCTAGGACCGC

Downstream 100 bases:

>100_bases
AAAGGGTTGCGTCGCGCCAATCATGGAGCGCCCCGTAAACTAGACATCACGACACCCCGCCCAACAACCGATAGACGGGA
GTGCCTTTGCTTGCGATTCT

Product: putative ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 728; Mature: 727

Protein sequence:

>728_residues
MSSLTLTARLNTSAVDSRRGVVRLHPEAIAALGIREWDAISLTGSRTTAAVVGVAPRSVPAGTALLDDVTLSNAGLREDA
SVIVAAVTVYGARSITVSGSSIATQSVSSATLRMALLGKVMTVGDTVSLLPRDLGPGTSTSEATSALTRSVGITWTSELL
TVTAVDPDGPVSVQPNSLVSWQGSTATSATSATAARQTELAPAAGPAPAASTVISVEDLKGSQAQATRLTEWLKLALDEP
ELLKTLGAQPNLGVLISGPAGVGKATLARAVCAARTLIELDGPEAGATSADGRLDMIREAVSRVRQSGGVLLISDIDALL
PAAAEPVATLILAELRTAVATSGVAFIATTAHPDALDARLRGPELCDRELGLSLPDAATRKSLLEVLLAKVPSQNLQLDE
IASRTPGFVVADLAALVREAALRAAARASEKASAPALAQEDLIGALSVIRPLSRSTTEEVAVGSITLDDVGDMVATKQAL
TEAVLWPLQHPDTFQRLGVDPPRGVLLYGPPGCGKTFVVRALASSGRLSVHAVKGAELMDKWVGSSEQAVRDLFRRARDS
APSLVFLDEVDALAPRRGQSFDSGVTDRVVAALLTELDGVEPLRDVVVLGATNRPELIDPALLRPGRMERLVFVEPPDAQ
ARTDILRTAARSVPLGADVDLNALAADLDGFSAADCAALLREAAMAAMRRSIDAADVTSADIHTARSVVRPSLDPVQVAS
LRAFADNR

Sequences:

>Translated_728_residues
MSSLTLTARLNTSAVDSRRGVVRLHPEAIAALGIREWDAISLTGSRTTAAVVGVAPRSVPAGTALLDDVTLSNAGLREDA
SVIVAAVTVYGARSITVSGSSIATQSVSSATLRMALLGKVMTVGDTVSLLPRDLGPGTSTSEATSALTRSVGITWTSELL
TVTAVDPDGPVSVQPNSLVSWQGSTATSATSATAARQTELAPAAGPAPAASTVISVEDLKGSQAQATRLTEWLKLALDEP
ELLKTLGAQPNLGVLISGPAGVGKATLARAVCAARTLIELDGPEAGATSADGRLDMIREAVSRVRQSGGVLLISDIDALL
PAAAEPVATLILAELRTAVATSGVAFIATTAHPDALDARLRGPELCDRELGLSLPDAATRKSLLEVLLAKVPSQNLQLDE
IASRTPGFVVADLAALVREAALRAAARASEKASAPALAQEDLIGALSVIRPLSRSTTEEVAVGSITLDDVGDMVATKQAL
TEAVLWPLQHPDTFQRLGVDPPRGVLLYGPPGCGKTFVVRALASSGRLSVHAVKGAELMDKWVGSSEQAVRDLFRRARDS
APSLVFLDEVDALAPRRGQSFDSGVTDRVVAALLTELDGVEPLRDVVVLGATNRPELIDPALLRPGRMERLVFVEPPDAQ
ARTDILRTAARSVPLGADVDLNALAADLDGFSAADCAALLREAAMAAMRRSIDAADVTSADIHTARSVVRPSLDPVQVAS
LRAFADNR
>Mature_727_residues
SSLTLTARLNTSAVDSRRGVVRLHPEAIAALGIREWDAISLTGSRTTAAVVGVAPRSVPAGTALLDDVTLSNAGLREDAS
VIVAAVTVYGARSITVSGSSIATQSVSSATLRMALLGKVMTVGDTVSLLPRDLGPGTSTSEATSALTRSVGITWTSELLT
VTAVDPDGPVSVQPNSLVSWQGSTATSATSATAARQTELAPAAGPAPAASTVISVEDLKGSQAQATRLTEWLKLALDEPE
LLKTLGAQPNLGVLISGPAGVGKATLARAVCAARTLIELDGPEAGATSADGRLDMIREAVSRVRQSGGVLLISDIDALLP
AAAEPVATLILAELRTAVATSGVAFIATTAHPDALDARLRGPELCDRELGLSLPDAATRKSLLEVLLAKVPSQNLQLDEI
ASRTPGFVVADLAALVREAALRAAARASEKASAPALAQEDLIGALSVIRPLSRSTTEEVAVGSITLDDVGDMVATKQALT
EAVLWPLQHPDTFQRLGVDPPRGVLLYGPPGCGKTFVVRALASSGRLSVHAVKGAELMDKWVGSSEQAVRDLFRRARDSA
PSLVFLDEVDALAPRRGQSFDSGVTDRVVAALLTELDGVEPLRDVVVLGATNRPELIDPALLRPGRMERLVFVEPPDAQA
RTDILRTAARSVPLGADVDLNALAADLDGFSAADCAALLREAAMAAMRRSIDAADVTSADIHTARSVVRPSLDPVQVASL
RAFADNR

Specific function: Seems To Act As An ATP-Dependent Zinc Metallopeptidase. Involved In The Degradation Of Sigma-32. Degrades Carboxy- Terminal-Tagged Cytoplasmic Proteins. These Proteins Are Tagged With An 11-Amino-Acid Nonpolar Destabilizing Tail VIa A Mechanism Involving

COG id: COG0464

COG function: function code O; ATPases of the AAA+ class

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AAA ATPase family. CDC48 subfamily [H]

Homologues:

Organism=Homo sapiens, GI157671927, Length=545, Percent_Identity=38.7155963302752, Blast_Score=342, Evalue=7e-94,
Organism=Homo sapiens, GI6005942, Length=554, Percent_Identity=32.4909747292419, Blast_Score=295, Evalue=7e-80,
Organism=Homo sapiens, GI45643125, Length=551, Percent_Identity=35.3901996370236, Blast_Score=293, Evalue=4e-79,
Organism=Homo sapiens, GI45643123, Length=551, Percent_Identity=35.3901996370236, Blast_Score=293, Evalue=5e-79,
Organism=Homo sapiens, GI229577436, Length=508, Percent_Identity=36.2204724409449, Blast_Score=286, Evalue=6e-77,
Organism=Homo sapiens, GI4505725, Length=477, Percent_Identity=35.4297693920335, Blast_Score=239, Evalue=8e-63,
Organism=Homo sapiens, GI194018488, Length=470, Percent_Identity=35.531914893617, Blast_Score=204, Evalue=2e-52,
Organism=Homo sapiens, GI195539395, Length=230, Percent_Identity=39.5652173913043, Blast_Score=188, Evalue=1e-47,
Organism=Homo sapiens, GI24497618, Length=263, Percent_Identity=39.5437262357414, Blast_Score=187, Evalue=2e-47,
Organism=Homo sapiens, GI153792536, Length=233, Percent_Identity=42.0600858369099, Blast_Score=183, Evalue=4e-46,
Organism=Homo sapiens, GI21361144, Length=235, Percent_Identity=38.7234042553192, Blast_Score=183, Evalue=4e-46,
Organism=Homo sapiens, GI24430155, Length=228, Percent_Identity=39.4736842105263, Blast_Score=180, Evalue=4e-45,
Organism=Homo sapiens, GI5729991, Length=228, Percent_Identity=39.4736842105263, Blast_Score=180, Evalue=4e-45,
Organism=Homo sapiens, GI89064750, Length=228, Percent_Identity=39.4736842105263, Blast_Score=180, Evalue=5e-45,
Organism=Homo sapiens, GI24497435, Length=243, Percent_Identity=38.2716049382716, Blast_Score=177, Evalue=3e-44,
Organism=Homo sapiens, GI24430151, Length=246, Percent_Identity=38.2113821138211, Blast_Score=177, Evalue=3e-44,
Organism=Homo sapiens, GI5901990, Length=238, Percent_Identity=39.0756302521008, Blast_Score=172, Evalue=1e-42,
Organism=Homo sapiens, GI4506209, Length=230, Percent_Identity=40, Blast_Score=171, Evalue=2e-42,
Organism=Homo sapiens, GI300192933, Length=259, Percent_Identity=35.9073359073359, Blast_Score=164, Evalue=4e-40,
Organism=Homo sapiens, GI14149767, Length=239, Percent_Identity=38.9121338912134, Blast_Score=162, Evalue=1e-39,
Organism=Homo sapiens, GI62177112, Length=239, Percent_Identity=38.9121338912134, Blast_Score=162, Evalue=1e-39,
Organism=Homo sapiens, GI156564401, Length=235, Percent_Identity=38.7234042553192, Blast_Score=161, Evalue=2e-39,
Organism=Homo sapiens, GI310125280, Length=233, Percent_Identity=39.0557939914163, Blast_Score=160, Evalue=3e-39,
Organism=Homo sapiens, GI310125282, Length=235, Percent_Identity=38.7234042553192, Blast_Score=160, Evalue=6e-39,
Organism=Homo sapiens, GI21327685, Length=233, Percent_Identity=36.0515021459227, Blast_Score=159, Evalue=1e-38,
Organism=Homo sapiens, GI7657689, Length=233, Percent_Identity=36.0515021459227, Blast_Score=159, Evalue=1e-38,
Organism=Homo sapiens, GI7019569, Length=257, Percent_Identity=34.6303501945525, Blast_Score=152, Evalue=1e-36,
Organism=Homo sapiens, GI4507173, Length=244, Percent_Identity=35.655737704918, Blast_Score=147, Evalue=5e-35,
Organism=Homo sapiens, GI31742536, Length=265, Percent_Identity=32.4528301886792, Blast_Score=146, Evalue=7e-35,
Organism=Homo sapiens, GI112789543, Length=265, Percent_Identity=32.4528301886792, Blast_Score=146, Evalue=7e-35,
Organism=Homo sapiens, GI226371754, Length=273, Percent_Identity=32.2344322344322, Blast_Score=145, Evalue=1e-34,
Organism=Homo sapiens, GI17865802, Length=260, Percent_Identity=32.6923076923077, Blast_Score=142, Evalue=1e-33,
Organism=Homo sapiens, GI11875211, Length=270, Percent_Identity=34.4444444444444, Blast_Score=135, Evalue=2e-31,
Organism=Homo sapiens, GI40806170, Length=270, Percent_Identity=34.4444444444444, Blast_Score=135, Evalue=2e-31,
Organism=Homo sapiens, GI31377644, Length=254, Percent_Identity=31.8897637795276, Blast_Score=131, Evalue=2e-30,
Organism=Homo sapiens, GI64084766, Length=273, Percent_Identity=30.4029304029304, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI40806173, Length=152, Percent_Identity=34.2105263157895, Blast_Score=91, Evalue=4e-18,
Organism=Homo sapiens, GI116292174, Length=263, Percent_Identity=29.6577946768061, Blast_Score=79, Evalue=1e-14,
Organism=Escherichia coli, GI1789568, Length=248, Percent_Identity=39.1129032258064, Blast_Score=181, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI17532375, Length=623, Percent_Identity=32.2632423756019, Blast_Score=311, Evalue=1e-84,
Organism=Caenorhabditis elegans, GI17531535, Length=562, Percent_Identity=32.0284697508897, Blast_Score=293, Evalue=2e-79,
Organism=Caenorhabditis elegans, GI17537217, Length=589, Percent_Identity=32.258064516129, Blast_Score=275, Evalue=8e-74,
Organism=Caenorhabditis elegans, GI17508053, Length=316, Percent_Identity=43.0379746835443, Blast_Score=246, Evalue=4e-65,
Organism=Caenorhabditis elegans, GI25153574, Length=398, Percent_Identity=33.4170854271357, Blast_Score=215, Evalue=7e-56,
Organism=Caenorhabditis elegans, GI17562804, Length=492, Percent_Identity=30.8943089430894, Blast_Score=205, Evalue=8e-53,
Organism=Caenorhabditis elegans, GI193209502, Length=225, Percent_Identity=44, Blast_Score=201, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI71987372, Length=230, Percent_Identity=41.304347826087, Blast_Score=189, Evalue=6e-48,
Organism=Caenorhabditis elegans, GI71987364, Length=230, Percent_Identity=41.304347826087, Blast_Score=189, Evalue=6e-48,
Organism=Caenorhabditis elegans, GI17508701, Length=239, Percent_Identity=38.9121338912134, Blast_Score=183, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI17554784, Length=232, Percent_Identity=40.0862068965517, Blast_Score=179, Evalue=3e-45,
Organism=Caenorhabditis elegans, GI17554786, Length=243, Percent_Identity=38.2716049382716, Blast_Score=176, Evalue=3e-44,
Organism=Caenorhabditis elegans, GI17563250, Length=246, Percent_Identity=38.2113821138211, Blast_Score=174, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI25144281, Length=313, Percent_Identity=33.5463258785943, Blast_Score=172, Evalue=8e-43,
Organism=Caenorhabditis elegans, GI25144278, Length=313, Percent_Identity=33.5463258785943, Blast_Score=172, Evalue=8e-43,
Organism=Caenorhabditis elegans, GI193206116, Length=233, Percent_Identity=39.9141630901288, Blast_Score=169, Evalue=4e-42,
Organism=Caenorhabditis elegans, GI133931034, Length=233, Percent_Identity=39.9141630901288, Blast_Score=169, Evalue=5e-42,
Organism=Caenorhabditis elegans, GI193206114, Length=233, Percent_Identity=39.9141630901288, Blast_Score=169, Evalue=5e-42,
Organism=Caenorhabditis elegans, GI17563248, Length=229, Percent_Identity=40.174672489083, Blast_Score=165, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI17505546, Length=226, Percent_Identity=35.8407079646018, Blast_Score=157, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI17508421, Length=292, Percent_Identity=35.6164383561644, Blast_Score=156, Evalue=4e-38,
Organism=Caenorhabditis elegans, GI32563584, Length=295, Percent_Identity=35.2542372881356, Blast_Score=154, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI25146157, Length=277, Percent_Identity=33.2129963898917, Blast_Score=152, Evalue=4e-37,
Organism=Caenorhabditis elegans, GI86561515, Length=255, Percent_Identity=32.156862745098, Blast_Score=147, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI17554264, Length=228, Percent_Identity=35.0877192982456, Blast_Score=142, Evalue=6e-34,
Organism=Caenorhabditis elegans, GI133901662, Length=228, Percent_Identity=36.8421052631579, Blast_Score=140, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI133901658, Length=228, Percent_Identity=36.8421052631579, Blast_Score=140, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17560432, Length=270, Percent_Identity=35.9259259259259, Blast_Score=137, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI115534323, Length=272, Percent_Identity=33.0882352941176, Blast_Score=130, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI71994521, Length=234, Percent_Identity=34.6153846153846, Blast_Score=125, Evalue=7e-29,
Organism=Caenorhabditis elegans, GI17541226, Length=220, Percent_Identity=33.6363636363636, Blast_Score=123, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17541224, Length=220, Percent_Identity=33.6363636363636, Blast_Score=123, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6320077, Length=612, Percent_Identity=33.0065359477124, Blast_Score=308, Evalue=2e-84,
Organism=Saccharomyces cerevisiae, GI6323429, Length=577, Percent_Identity=33.9688041594454, Blast_Score=293, Evalue=5e-80,
Organism=Saccharomyces cerevisiae, GI6322994, Length=564, Percent_Identity=33.1560283687943, Blast_Score=271, Evalue=3e-73,
Organism=Saccharomyces cerevisiae, GI6322651, Length=379, Percent_Identity=33.245382585752, Blast_Score=204, Evalue=6e-53,
Organism=Saccharomyces cerevisiae, GI6324000, Length=484, Percent_Identity=30.5785123966942, Blast_Score=197, Evalue=4e-51,
Organism=Saccharomyces cerevisiae, GI6321390, Length=243, Percent_Identity=39.0946502057613, Blast_Score=187, Evalue=6e-48,
Organism=Saccharomyces cerevisiae, GI6320602, Length=230, Percent_Identity=42.1739130434783, Blast_Score=186, Evalue=2e-47,
Organism=Saccharomyces cerevisiae, GI6321709, Length=236, Percent_Identity=39.8305084745763, Blast_Score=181, Evalue=4e-46,
Organism=Saccharomyces cerevisiae, GI6320197, Length=281, Percent_Identity=34.5195729537367, Blast_Score=176, Evalue=1e-44,
Organism=Saccharomyces cerevisiae, GI6324833, Length=263, Percent_Identity=35.7414448669202, Blast_Score=174, Evalue=3e-44,
Organism=Saccharomyces cerevisiae, GI6323736, Length=275, Percent_Identity=36.3636363636364, Blast_Score=165, Evalue=3e-41,
Organism=Saccharomyces cerevisiae, GI6322704, Length=230, Percent_Identity=38.2608695652174, Blast_Score=162, Evalue=2e-40,
Organism=Saccharomyces cerevisiae, GI6325281, Length=243, Percent_Identity=35.3909465020576, Blast_Score=158, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6324691, Length=226, Percent_Identity=36.283185840708, Blast_Score=153, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6325431, Length=248, Percent_Identity=35.0806451612903, Blast_Score=153, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6320854, Length=239, Percent_Identity=37.2384937238494, Blast_Score=149, Evalue=1e-36,
Organism=Saccharomyces cerevisiae, GI6319554, Length=230, Percent_Identity=35.2173913043478, Blast_Score=146, Evalue=1e-35,
Organism=Saccharomyces cerevisiae, GI6321465, Length=255, Percent_Identity=34.5098039215686, Blast_Score=140, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6325183, Length=291, Percent_Identity=30.5841924398625, Blast_Score=130, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6320887, Length=299, Percent_Identity=28.4280936454849, Blast_Score=123, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6320583, Length=208, Percent_Identity=27.8846153846154, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI17137560, Length=512, Percent_Identity=35.7421875, Blast_Score=303, Evalue=3e-82,
Organism=Drosophila melanogaster, GI161076486, Length=512, Percent_Identity=35.7421875, Blast_Score=303, Evalue=3e-82,
Organism=Drosophila melanogaster, GI161076488, Length=512, Percent_Identity=35.7421875, Blast_Score=303, Evalue=4e-82,
Organism=Drosophila melanogaster, GI19921202, Length=492, Percent_Identity=36.1788617886179, Blast_Score=286, Evalue=3e-77,
Organism=Drosophila melanogaster, GI24660075, Length=287, Percent_Identity=41.1149825783972, Blast_Score=228, Evalue=1e-59,
Organism=Drosophila melanogaster, GI281365776, Length=287, Percent_Identity=41.1149825783972, Blast_Score=228, Evalue=1e-59,
Organism=Drosophila melanogaster, GI45552965, Length=287, Percent_Identity=41.1149825783972, Blast_Score=228, Evalue=1e-59,
Organism=Drosophila melanogaster, GI21355121, Length=515, Percent_Identity=31.6504854368932, Blast_Score=219, Evalue=7e-57,
Organism=Drosophila melanogaster, GI24656820, Length=496, Percent_Identity=32.0564516129032, Blast_Score=209, Evalue=4e-54,
Organism=Drosophila melanogaster, GI24656825, Length=440, Percent_Identity=32.9545454545455, Blast_Score=207, Evalue=2e-53,
Organism=Drosophila melanogaster, GI24652279, Length=198, Percent_Identity=44.4444444444444, Blast_Score=189, Evalue=7e-48,
Organism=Drosophila melanogaster, GI281361487, Length=232, Percent_Identity=40.0862068965517, Blast_Score=187, Evalue=2e-47,
Organism=Drosophila melanogaster, GI18860063, Length=228, Percent_Identity=40.7894736842105, Blast_Score=187, Evalue=2e-47,
Organism=Drosophila melanogaster, GI281363136, Length=303, Percent_Identity=37.953795379538, Blast_Score=186, Evalue=4e-47,
Organism=Drosophila melanogaster, GI78707192, Length=303, Percent_Identity=37.953795379538, Blast_Score=186, Evalue=4e-47,
Organism=Drosophila melanogaster, GI24651451, Length=263, Percent_Identity=37.6425855513308, Blast_Score=183, Evalue=3e-46,
Organism=Drosophila melanogaster, GI17738151, Length=239, Percent_Identity=38.9121338912134, Blast_Score=183, Evalue=3e-46,
Organism=Drosophila melanogaster, GI19920408, Length=242, Percent_Identity=38.4297520661157, Blast_Score=182, Evalue=6e-46,
Organism=Drosophila melanogaster, GI24649446, Length=246, Percent_Identity=38.2113821138211, Blast_Score=177, Evalue=2e-44,
Organism=Drosophila melanogaster, GI24640100, Length=230, Percent_Identity=38.2608695652174, Blast_Score=175, Evalue=8e-44,
Organism=Drosophila melanogaster, GI24663015, Length=258, Percent_Identity=37.2093023255814, Blast_Score=173, Evalue=5e-43,
Organism=Drosophila melanogaster, GI17137738, Length=231, Percent_Identity=39.8268398268398, Blast_Score=170, Evalue=3e-42,
Organism=Drosophila melanogaster, GI24658770, Length=247, Percent_Identity=38.0566801619433, Blast_Score=160, Evalue=4e-39,
Organism=Drosophila melanogaster, GI24644145, Length=234, Percent_Identity=39.7435897435897, Blast_Score=159, Evalue=9e-39,
Organism=Drosophila melanogaster, GI24639391, Length=249, Percent_Identity=34.9397590361446, Blast_Score=150, Evalue=4e-36,
Organism=Drosophila melanogaster, GI28573010, Length=226, Percent_Identity=38.0530973451327, Blast_Score=149, Evalue=6e-36,
Organism=Drosophila melanogaster, GI28574878, Length=242, Percent_Identity=35.9504132231405, Blast_Score=148, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24665814, Length=242, Percent_Identity=35.9504132231405, Blast_Score=147, Evalue=2e-35,
Organism=Drosophila melanogaster, GI17864540, Length=219, Percent_Identity=38.8127853881278, Blast_Score=147, Evalue=3e-35,
Organism=Drosophila melanogaster, GI18859657, Length=232, Percent_Identity=34.4827586206897, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24581396, Length=230, Percent_Identity=37.8260869565217, Blast_Score=142, Evalue=6e-34,
Organism=Drosophila melanogaster, GI281360146, Length=233, Percent_Identity=36.0515021459227, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI281360138, Length=233, Percent_Identity=36.0515021459227, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI281360142, Length=233, Percent_Identity=36.0515021459227, Blast_Score=140, Evalue=3e-33,
Organism=Drosophila melanogaster, GI21357333, Length=233, Percent_Identity=36.0515021459227, Blast_Score=140, Evalue=3e-33,
Organism=Drosophila melanogaster, GI281360144, Length=233, Percent_Identity=36.0515021459227, Blast_Score=140, Evalue=4e-33,
Organism=Drosophila melanogaster, GI281360140, Length=233, Percent_Identity=36.0515021459227, Blast_Score=140, Evalue=4e-33,
Organism=Drosophila melanogaster, GI281360136, Length=233, Percent_Identity=36.0515021459227, Blast_Score=140, Evalue=4e-33,
Organism=Drosophila melanogaster, GI24644411, Length=233, Percent_Identity=36.0515021459227, Blast_Score=140, Evalue=4e-33,
Organism=Drosophila melanogaster, GI20129423, Length=264, Percent_Identity=32.5757575757576, Blast_Score=137, Evalue=3e-32,
Organism=Drosophila melanogaster, GI20129529, Length=304, Percent_Identity=30.9210526315789, Blast_Score=128, Evalue=2e-29,
Organism=Drosophila melanogaster, GI28571849, Length=274, Percent_Identity=35.036496350365, Blast_Score=127, Evalue=3e-29,
Organism=Drosophila melanogaster, GI28571847, Length=274, Percent_Identity=35.036496350365, Blast_Score=127, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24639486, Length=241, Percent_Identity=33.195020746888, Blast_Score=121, Evalue=2e-27,
Organism=Drosophila melanogaster, GI45554047, Length=167, Percent_Identity=34.7305389221557, Blast_Score=114, Evalue=3e-25,
Organism=Drosophila melanogaster, GI20129417, Length=175, Percent_Identity=32, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24583262, Length=175, Percent_Identity=32, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR003593
- InterPro:   IPR005938
- InterPro:   IPR003959
- InterPro:   IPR003960
- InterPro:   IPR003338
- InterPro:   IPR004201
- InterPro:   IPR015415 [H]

Pfam domain/function: PF00004 AAA; PF02933 CDC48_2; PF02359 CDC48_N; PF09336 Vps4_C [H]

EC number: 3.4.24.- [C]

Molecular weight: Translated: 75394; Mature: 75262

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS00674 AAA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSLTLTARLNTSAVDSRRGVVRLHPEAIAALGIREWDAISLTGSRTTAAVVGVAPRSVP
CCCEEEEEECCCHHHHCCCCEEEECHHHHHHHCCCCCCEEEECCCCCEEEEEECCCCCCC
AGTALLDDVTLSNAGLREDASVIVAAVTVYGARSITVSGSSIATQSVSSATLRMALLGKV
CCCHHHHCCCCCCCCCCCCHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHH
MTVGDTVSLLPRDLGPGTSTSEATSALTRSVGITWTSELLTVTAVDPDGPVSVQPNSLVS
HHCCCHHHHHCCCCCCCCCCHHHHHHHHHHCCCEEECCEEEEEEECCCCCCEECCCCEEE
WQGSTATSATSATAARQTELAPAAGPAPAASTVISVEDLKGSQAQATRLTEWLKLALDEP
ECCCCCCCCHHHHHHHHHCCCCCCCCCCCHHEEEEHHHCCCCHHHHHHHHHHHHHHCCCH
ELLKTLGAQPNLGVLISGPAGVGKATLARAVCAARTLIELDGPEAGATSADGRLDMIREA
HHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHEEECCCCCCCCCCCCHHHHHHHH
VSRVRQSGGVLLISDIDALLPAAAEPVATLILAELRTAVATSGVAFIATTAHPDALDARL
HHHHHHCCCEEEEECHHHHHCCCCHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHC
RGPELCDRELGLSLPDAATRKSLLEVLLAKVPSQNLQLDEIASRTPGFVVADLAALVREA
CCHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCHHHHHHHHHHHHH
ALRAAARASEKASAPALAQEDLIGALSVIRPLSRSTTEEVAVGSITLDDVGDMVATKQAL
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHEECEEEHHHHHHHHHHHHHH
TEAVLWPLQHPDTFQRLGVDPPRGVLLYGPPGCGKTFVVRALASSGRLSVHAVKGAELMD
HHHHHCCCCCCCHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHCCCCEEEEEECCHHHHH
KWVGSSEQAVRDLFRRARDSAPSLVFLDEVDALAPRRGQSFDSGVTDRVVAALLTELDGV
HHCCCHHHHHHHHHHHHHCCCCCEEEECCHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCC
EPLRDVVVLGATNRPELIDPALLRPGRMERLVFVEPPDAQARTDILRTAARSVPLGADVD
CCHHHEEEECCCCCCCCCCHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCCC
LNALAADLDGFSAADCAALLREAAMAAMRRSIDAADVTSADIHTARSVVRPSLDPVQVAS
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHCCCCCHHHHHH
LRAFADNR
HHHHCCCC
>Mature Secondary Structure 
SSLTLTARLNTSAVDSRRGVVRLHPEAIAALGIREWDAISLTGSRTTAAVVGVAPRSVP
CCEEEEEECCCHHHHCCCCEEEECHHHHHHHCCCCCCEEEECCCCCEEEEEECCCCCCC
AGTALLDDVTLSNAGLREDASVIVAAVTVYGARSITVSGSSIATQSVSSATLRMALLGKV
CCCHHHHCCCCCCCCCCCCHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHH
MTVGDTVSLLPRDLGPGTSTSEATSALTRSVGITWTSELLTVTAVDPDGPVSVQPNSLVS
HHCCCHHHHHCCCCCCCCCCHHHHHHHHHHCCCEEECCEEEEEEECCCCCCEECCCCEEE
WQGSTATSATSATAARQTELAPAAGPAPAASTVISVEDLKGSQAQATRLTEWLKLALDEP
ECCCCCCCCHHHHHHHHHCCCCCCCCCCCHHEEEEHHHCCCCHHHHHHHHHHHHHHCCCH
ELLKTLGAQPNLGVLISGPAGVGKATLARAVCAARTLIELDGPEAGATSADGRLDMIREA
HHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHEEECCCCCCCCCCCCHHHHHHHH
VSRVRQSGGVLLISDIDALLPAAAEPVATLILAELRTAVATSGVAFIATTAHPDALDARL
HHHHHHCCCEEEEECHHHHHCCCCHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHC
RGPELCDRELGLSLPDAATRKSLLEVLLAKVPSQNLQLDEIASRTPGFVVADLAALVREA
CCHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCHHHHHHHHHHHHH
ALRAAARASEKASAPALAQEDLIGALSVIRPLSRSTTEEVAVGSITLDDVGDMVATKQAL
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHEECEEEHHHHHHHHHHHHHH
TEAVLWPLQHPDTFQRLGVDPPRGVLLYGPPGCGKTFVVRALASSGRLSVHAVKGAELMD
HHHHHCCCCCCCHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHCCCCEEEEEECCHHHHH
KWVGSSEQAVRDLFRRARDSAPSLVFLDEVDALAPRRGQSFDSGVTDRVVAALLTELDGV
HHCCCHHHHHHHHHHHHHCCCCCEEEECCHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCC
EPLRDVVVLGATNRPELIDPALLRPGRMERLVFVEPPDAQARTDILRTAARSVPLGADVD
CCHHHEEEECCCCCCCCCCHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCCC
LNALAADLDGFSAADCAALLREAAMAAMRRSIDAADVTSADIHTARSVVRPSLDPVQVAS
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHCCCCCHHHHHH
LRAFADNR
HHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Metalloendopeptidases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]