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The map label for this gene is clpC [H]

Identifier: 169627650

GI number: 169627650

Start: 546836

End: 549370

Strand: Direct

Name: clpC [H]

Synonym: MAB_0546

Alternate gene names: 169627650

Gene position: 546836-549370 (Clockwise)

Preceding gene: 169627649

Following gene: 169627654

Centisome position: 10.79

GC content: 64.81

Gene sequence:

>2535_bases
ATGTTCGAGAGATTCACTGACCGCGCCAGGCGGGTGGTTGTGCTGGCCCAAGAAGAGGCCCGCATGCTCAACCACAACTA
CATCGGCACCGAGCACATCCTGCTGGGTCTGATCCATGAGGGCGAGGGCGTCGCCGCCAAGTCGCTCGAGTCGTTGGGCA
TCTCGCTGGAAGGGGTGCGCAGCCAGGTCGAGGAGATCATCGGCCAGGGTCAGCAGGCGCCGTCCGGGCACATTCCGTTC
ACTCCGCGTGCCAAGAAGGTGCTGGAGCTGAGCCTGCGCGAGGCGCTGCAGCTCGGCCACAACTACATCGGCACCGAGCA
CATCCTGCTCGGCCTGATTCGCGAGGGCGAGGGCGTTGCCGCACAGGTGCTCGTCAAGCTGGGCGCCGAGCTGACTCGGG
TGCGTCAGCAGGTCATCCAGCTGCTCAGTGGCTACCAGGGCAAGGAGACCGCAGAATCGGGTACCGGTGGCAGGGGCGGA
GAAGCCGGCACACCTTCTACGTCGCTGGTGCTCGACCAGTTCGGCCGCAATCTGACCGCGGCCGCCATGGAGGGCAAGCT
CGATCCGGTCATCGGCCGTGAGAAGGAAATCGAGCGGGTCATGCAGGTGCTGAGCCGCCGCACCAAGAACAACCCGGTGC
TGATCGGCGAGCCCGGTGTCGGCAAGACCGCCGTCGTCGAGGGTCTGGCCCAGGCGATCGTGCACGGCGAGGTGCCCGAG
ACACTGAAGAACAAGCAGCTGTACACCTTGGACCTGGGGTCCCTGGTGGCCGGCAGCCGCTACCGCGGTGATTTCGAGGA
ACGCCTCAAGAAGGTGCTCAAGGAGATCAACACCCGTGGTGACATCATCCTGTTCATCGACGAGCTGCACACGCTGGTGG
GTGCGGGCGCGGCCGAGGGCGCGATCGACGCGGCCTCGATCCTGAAGCCGAAGCTGGCTCGTGGCGAGCTGCAGACCATC
GGTGCGACCACACTCGACGAGTACCGCAAGTACATCGAGAAGGACGCCGCCCTGGAGCGCCGGTTCCAGCCGGTGCAGGT
GGGCGAGCCGACGGTCGAGCACACCATCGAGATCCTCAAGGGTCTACGCGACCGCTACGAGGCACACCACCGGGTGTCCA
TCACCGATGGCGCATTGGTTGCCGCGGCGACCCTGGCCGATCGGTACATCAACGACAGGTTCTTGCCCGACAAGGCGATC
GACCTGATCGACGAGGCCGGTGCCCGCATGCGCATCCGCCGCATGACCGCGCCGCCAGACCTGCGCGAGTTCGACGAGAA
GATCGCCGATGCGCGCCGGGAGAAGGAATCGGCCATCGACGCGCAGGACTTCGAGAAGGCCGCGCGCCTGCGCGACTCCG
AGAAGCAGCTGGTGGCCCAGCGTGCCGATCGCGAAAAGCAATGGCGTTCAGGTGACTTAGATGTGGTCGCGGAAGTCGAT
GATGAGCAGATCGCCGAGGTGCTGGGCAACTGGACCGGTATCCCCGTGTTCAAGCTGACCGAGGAAGAAACCACTCGGCT
GCTGCGCATGGAGGACGAGCTGCACAAGCGGATCATCGGCCAGGAGGACGCCGTCAAGGCCGTCTCCAAGGCCATCCGCC
GCACCCGTGCCGGTCTGAAGGACCCGCGGCGCCCCTCGGGCTCGTTCATCTTCGCCGGGCCGTCCGGTGTCGGTAAGACC
GAGCTGTCCAAGGCGCTGGCCAACTTCCTGTTCGGCGACGACGACGCGCTCATCCAGATCGACATGGGCGAGTTCCACGA
CCGCTTCACCGCCTCAAGGCTTTTCGGCGCTCCCCCGGGATACGTCGGCTACGAGGAGGGCGGCCAGCTCACCGAGAAGG
TGCGCCGGAAGCCGTTCAGCGTGGTGTTGTTCGACGAGATCGAGAAGGCTCACCAGGAGATCTACAACACCCTGTTGCAG
GTTCTCGAGGACGGTCGCCTCACCGACGGCCAGGGACGCACGGTCGATTTCAAGAACACCGTGCTGATCTTCACCTCGAA
CCTGGGCACGTCGGATATCTCGAAGGCCGTCGGCCTCGGATTCTCCGAAGGTGCGGCCGGCTCGAACTACGAGCGGATGA
AGCAGAAGGTCCACGACGAGCTCAAGAAGCACTTCCGTCCTGAGTTCCTCAACCGCATCGATGACATCATCGTCTTCGAG
CAGCTGACGCAGGAACAGATCATCGAGATGGTCGACCTGATGATCGGGCGGGTGGGCAAGCAGCTCAAGACCAAAGACAT
GGCCATGGAGCTCACCGACAAGGCCAAGTCGCTGCTGGCCAAGCGCGGATTCGATCCGGTGCTAGGCGCCCGCCCGCTGC
GTCGGACCATTCAGCGCGAGATCGAGGACGCACTCTCGGAGAAGATTCTCTTCAACGAGGTCGGTCCCGGCGAGCTGGTC
ACCGTCGACGTCGAGAACTGGGACGGCGAGAGTGCCGGCGAGGACGCGAAGTTCACCTTCGTCGGCCGTCCGAAGCCCGC
ACTGGTCGCCGGTGAGGAGCCTGCCGCCGACCTGGCCGCCTCCGCCTCGGAGTAA

Upstream 100 bases:

>100_bases
TTAGGTCCTAGTGCCAGCGGGGATGAGTCGTTTGGGAAGAGCCCCAAGCGGCACCATGAACCGCTTGCGCAAAGGCCGGA
CGAGGAAGCGAGGGAGACCG

Downstream 100 bases:

>100_bases
ATCGGTTCTGATCGAACGCCCGGCTGTCGCATTATGCGGCGGCCGGGCGTTCGGCTTTTCGGGGAAGCCTTCCGCGCCGA
CACGCCGCGTTTGGAGCCCG

Product: ATP-dependent Clp protease ATP-binding subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 844; Mature: 844

Protein sequence:

>844_residues
MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLESLGISLEGVRSQVEEIIGQGQQAPSGHIPF
TPRAKKVLELSLREALQLGHNYIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQLLSGYQGKETAESGTGGRGG
EAGTPSTSLVLDQFGRNLTAAAMEGKLDPVIGREKEIERVMQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVHGEVPE
TLKNKQLYTLDLGSLVAGSRYRGDFEERLKKVLKEINTRGDIILFIDELHTLVGAGAAEGAIDAASILKPKLARGELQTI
GATTLDEYRKYIEKDAALERRFQPVQVGEPTVEHTIEILKGLRDRYEAHHRVSITDGALVAAATLADRYINDRFLPDKAI
DLIDEAGARMRIRRMTAPPDLREFDEKIADARREKESAIDAQDFEKAARLRDSEKQLVAQRADREKQWRSGDLDVVAEVD
DEQIAEVLGNWTGIPVFKLTEEETTRLLRMEDELHKRIIGQEDAVKAVSKAIRRTRAGLKDPRRPSGSFIFAGPSGVGKT
ELSKALANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPGYVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHQEIYNTLLQ
VLEDGRLTDGQGRTVDFKNTVLIFTSNLGTSDISKAVGLGFSEGAAGSNYERMKQKVHDELKKHFRPEFLNRIDDIIVFE
QLTQEQIIEMVDLMIGRVGKQLKTKDMAMELTDKAKSLLAKRGFDPVLGARPLRRTIQREIEDALSEKILFNEVGPGELV
TVDVENWDGESAGEDAKFTFVGRPKPALVAGEEPAADLAASASE

Sequences:

>Translated_844_residues
MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLESLGISLEGVRSQVEEIIGQGQQAPSGHIPF
TPRAKKVLELSLREALQLGHNYIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQLLSGYQGKETAESGTGGRGG
EAGTPSTSLVLDQFGRNLTAAAMEGKLDPVIGREKEIERVMQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVHGEVPE
TLKNKQLYTLDLGSLVAGSRYRGDFEERLKKVLKEINTRGDIILFIDELHTLVGAGAAEGAIDAASILKPKLARGELQTI
GATTLDEYRKYIEKDAALERRFQPVQVGEPTVEHTIEILKGLRDRYEAHHRVSITDGALVAAATLADRYINDRFLPDKAI
DLIDEAGARMRIRRMTAPPDLREFDEKIADARREKESAIDAQDFEKAARLRDSEKQLVAQRADREKQWRSGDLDVVAEVD
DEQIAEVLGNWTGIPVFKLTEEETTRLLRMEDELHKRIIGQEDAVKAVSKAIRRTRAGLKDPRRPSGSFIFAGPSGVGKT
ELSKALANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPGYVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHQEIYNTLLQ
VLEDGRLTDGQGRTVDFKNTVLIFTSNLGTSDISKAVGLGFSEGAAGSNYERMKQKVHDELKKHFRPEFLNRIDDIIVFE
QLTQEQIIEMVDLMIGRVGKQLKTKDMAMELTDKAKSLLAKRGFDPVLGARPLRRTIQREIEDALSEKILFNEVGPGELV
TVDVENWDGESAGEDAKFTFVGRPKPALVAGEEPAADLAASASE
>Mature_844_residues
MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLESLGISLEGVRSQVEEIIGQGQQAPSGHIPF
TPRAKKVLELSLREALQLGHNYIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQLLSGYQGKETAESGTGGRGG
EAGTPSTSLVLDQFGRNLTAAAMEGKLDPVIGREKEIERVMQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVHGEVPE
TLKNKQLYTLDLGSLVAGSRYRGDFEERLKKVLKEINTRGDIILFIDELHTLVGAGAAEGAIDAASILKPKLARGELQTI
GATTLDEYRKYIEKDAALERRFQPVQVGEPTVEHTIEILKGLRDRYEAHHRVSITDGALVAAATLADRYINDRFLPDKAI
DLIDEAGARMRIRRMTAPPDLREFDEKIADARREKESAIDAQDFEKAARLRDSEKQLVAQRADREKQWRSGDLDVVAEVD
DEQIAEVLGNWTGIPVFKLTEEETTRLLRMEDELHKRIIGQEDAVKAVSKAIRRTRAGLKDPRRPSGSFIFAGPSGVGKT
ELSKALANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPGYVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHQEIYNTLLQ
VLEDGRLTDGQGRTVDFKNTVLIFTSNLGTSDISKAVGLGFSEGAAGSNYERMKQKVHDELKKHFRPEFLNRIDDIIVFE
QLTQEQIIEMVDLMIGRVGKQLKTKDMAMELTDKAKSLLAKRGFDPVLGARPLRRTIQREIEDALSEKILFNEVGPGELV
TVDVENWDGESAGEDAKFTFVGRPKPALVAGEEPAADLAASASE

Specific function: Part Of A Stress-Induced Multi-Chaperone System, It Is Involved In The Recovery Of The Cell From Heat-Induced Damage, In Cooperation With Dnak, Dnaj And Grpe. Acts Before Dnak, In The Processing Of Protein Aggregates. Protein Binding Stimulates The Atpase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=321, Percent_Identity=33.9563862928349, Blast_Score=190, Evalue=5e-48,
Organism=Escherichia coli, GI1788943, Length=871, Percent_Identity=45.9242250287026, Blast_Score=728, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=812, Percent_Identity=37.9310344827586, Blast_Score=504, Evalue=1e-144,
Organism=Saccharomyces cerevisiae, GI6320464, Length=699, Percent_Identity=46.9241773962804, Blast_Score=608, Evalue=1e-175,
Organism=Saccharomyces cerevisiae, GI6323002, Length=429, Percent_Identity=41.4918414918415, Blast_Score=298, Evalue=2e-81,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150
- InterPro:   IPR001943 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small; PF02151 UVR [H]

EC number: NA

Molecular weight: Translated: 93259; Mature: 93259

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: PS50151 UVR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLESLGISLEGVR
CCCHHHHHCCEEEEEEHHHHHHHHCCCCCHHHHHEEEEECCCCHHHHHHHHHCCCHHHHH
SQVEEIIGQGQQAPSGHIPFTPRAKKVLELSLREALQLGHNYIGTEHILLGLIREGEGVA
HHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHCCHHHHHHHHHHCCCCHH
AQVLVKLGAELTRVRQQVIQLLSGYQGKETAESGTGGRGGEAGTPSTSLVLDQFGRNLTA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHH
AAMEGKLDPVIGREKEIERVMQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVHGEVPE
HHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCH
TLKNKQLYTLDLGSLVAGSRYRGDFEERLKKVLKEINTRGDIILFIDELHTLVGAGAAEG
HHCCCEEEEEEHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCEEEEHHHHHHHHCCCCCCC
AIDAASILKPKLARGELQTIGATTLDEYRKYIEKDAALERRFQPVQVGEPTVEHTIEILK
CHHHHHHHCCHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
GLRDRYEAHHRVSITDGALVAAATLADRYINDRFLPDKAIDLIDEAGARMRIRRMTAPPD
HHHHHHHCCCEEEECCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCEEEEECCCCCC
LREFDEKIADARREKESAIDAQDFEKAARLRDSEKQLVAQRADREKQWRSGDLDVVAEVD
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCEEEEECC
DEQIAEVLGNWTGIPVFKLTEEETTRLLRMEDELHKRIIGQEDAVKAVSKAIRRTRAGLK
HHHHHHHHCCCCCCCEEEECHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCC
DPRRPSGSFIFAGPSGVGKTELSKALANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPG
CCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHHCCCCCC
YVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHQEIYNTLLQVLEDGRLTDGQGRTVDFKNT
CCCCCCCCHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCE
VLIFTSNLGTSDISKAVGLGFSEGAAGSNYERMKQKVHDELKKHFRPEFLNRIDDIIVFE
EEEEECCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
QLTQEQIIEMVDLMIGRVGKQLKTKDMAMELTDKAKSLLAKRGFDPVLGARPLRRTIQRE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
IEDALSEKILFNEVGPGELVTVDVENWDGESAGEDAKFTFVGRPKPALVAGEEPAADLAA
HHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCEEEEECCCCCCEEECCCCHHHHHC
SASE
CCCC
>Mature Secondary Structure
MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLESLGISLEGVR
CCCHHHHHCCEEEEEEHHHHHHHHCCCCCHHHHHEEEEECCCCHHHHHHHHHCCCHHHHH
SQVEEIIGQGQQAPSGHIPFTPRAKKVLELSLREALQLGHNYIGTEHILLGLIREGEGVA
HHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHCCHHHHHHHHHHCCCCHH
AQVLVKLGAELTRVRQQVIQLLSGYQGKETAESGTGGRGGEAGTPSTSLVLDQFGRNLTA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHH
AAMEGKLDPVIGREKEIERVMQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVHGEVPE
HHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCH
TLKNKQLYTLDLGSLVAGSRYRGDFEERLKKVLKEINTRGDIILFIDELHTLVGAGAAEG
HHCCCEEEEEEHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCEEEEHHHHHHHHCCCCCCC
AIDAASILKPKLARGELQTIGATTLDEYRKYIEKDAALERRFQPVQVGEPTVEHTIEILK
CHHHHHHHCCHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
GLRDRYEAHHRVSITDGALVAAATLADRYINDRFLPDKAIDLIDEAGARMRIRRMTAPPD
HHHHHHHCCCEEEECCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCEEEEECCCCCC
LREFDEKIADARREKESAIDAQDFEKAARLRDSEKQLVAQRADREKQWRSGDLDVVAEVD
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCEEEEECC
DEQIAEVLGNWTGIPVFKLTEEETTRLLRMEDELHKRIIGQEDAVKAVSKAIRRTRAGLK
HHHHHHHHCCCCCCCEEEECHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCC
DPRRPSGSFIFAGPSGVGKTELSKALANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPG
CCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHHCCCCCC
YVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHQEIYNTLLQVLEDGRLTDGQGRTVDFKNT
CCCCCCCCHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCE
VLIFTSNLGTSDISKAVGLGFSEGAAGSNYERMKQKVHDELKKHFRPEFLNRIDDIIVFE
EEEEECCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
QLTQEQIIEMVDLMIGRVGKQLKTKDMAMELTDKAKSLLAKRGFDPVLGARPLRRTIQRE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
IEDALSEKILFNEVGPGELVTVDVENWDGESAGEDAKFTFVGRPKPALVAGEEPAADLAA
HHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCEEEEECCCCCCEEECCCCHHHHHC
SASE
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]