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The map label for this gene is panC [H]

Identifier: 169627645

GI number: 169627645

Start: 542296

End: 543228

Strand: Direct

Name: panC [H]

Synonym: MAB_0541

Alternate gene names: 169627645

Gene position: 542296-543228 (Clockwise)

Preceding gene: 169627644

Following gene: 169627646

Centisome position: 10.7

GC content: 65.17

Gene sequence:

>933_bases
ATGACGAGTTTGTATGGTCCGAAGGGGCCGAAGGGCTACCTTCGGGGAGAGCTGACCGTTCACCACGACCCCGAGACCAT
GTACGACGTGTCGAAGGCGTTGCGGCACACCGGCCGACGGATCGTCTTGGTGCCGACCATGGGTGCGCTGCATGAGGGCC
ATCTGACGCTGGTCCGGCACGCCCGGAAGGTGCCCGGTGCCGTTGTCGTGGTGTCCATCTTCGTCAACCCGCTGCAGTTC
GGTCCGGGCGAGGATCTCGAGGCGTATCCACGCACACTGGACTCCGATGTCGCGAAGTTGCGCGAGGAGGGTGTGGAGCT
GGTGTTCGCCCCGAATGCGGAGGCGATGTATCCGCATGGCCGGCGCACCACCGTGCAACCCGGTCCGCTAGGTGCTGAGC
TCGAAGGCGCTTCACGTCCAACGCACTTCGCCGGAATGCTCACGGTCGTGCTCAAACTGCTGCAAATCGTGGCGCCTGAC
CGCGCGTACTTCGGGGAGAAGGATTACCAGCAGCTGGTGCTCATCCGACAGATGGTCACCGATCTCAATATCACGACGCG
CATCGTTCCCGTGCCGATCGTCCGTGAGGCCGACGGGCTGGCGATGTCGTCGCGGAATGTGTACCTGAGCGAAGAGCACC
GTGAGCAGGCGGGGGCCCTATCGGCCGCCCTGCTTGCCGGAATCTATTCCGCTTCGGCAGGGGTAGAGGCAGCCCTGGAT
GCCGCGCGCGCCGTGCTCGATGAGGTGCCGGCCATCGAGGTCGACTATCTGGAGGTGCGCGGTGCCGATTTGGGTCCGGC
ACCCGCGCACGGGCCCGGCCGCATGCTGGTGGCGGCCAAGCTGGGGAGCACCAGGCTGTTGGACAACGTTCCCATCGAGA
TCGGACCAACGGGGCCGACAGACCCCGACCACGAGCTTCCCTGGCGAAATTGA

Upstream 100 bases:

>100_bases
GCAGCGCGCGCACGCCCCCCAATCGGTTTTCTCTGCACTGGAACCCCGCGACGCCGGTTAAGGCAAGCTAAGGCAAGGTA
AGGCAAGGTAAGGCACTGAG

Downstream 100 bases:

>100_bases
CTGGAGGACATGATGTTCCGCACGATGATGAAGTCGAAGATCCATCGCGCCACGGTGACGCACGCCGACCTGCATTACGT
CGGCTCGGTGACCATCGACC

Product: pantoate--beta-alanine ligase

Products: NA

Alternate protein names: PS; Pantoate--beta-alanine ligase; Pantoate-activating enzyme [H]

Number of amino acids: Translated: 310; Mature: 309

Protein sequence:

>310_residues
MTSLYGPKGPKGYLRGELTVHHDPETMYDVSKALRHTGRRIVLVPTMGALHEGHLTLVRHARKVPGAVVVVSIFVNPLQF
GPGEDLEAYPRTLDSDVAKLREEGVELVFAPNAEAMYPHGRRTTVQPGPLGAELEGASRPTHFAGMLTVVLKLLQIVAPD
RAYFGEKDYQQLVLIRQMVTDLNITTRIVPVPIVREADGLAMSSRNVYLSEEHREQAGALSAALLAGIYSASAGVEAALD
AARAVLDEVPAIEVDYLEVRGADLGPAPAHGPGRMLVAAKLGSTRLLDNVPIEIGPTGPTDPDHELPWRN

Sequences:

>Translated_310_residues
MTSLYGPKGPKGYLRGELTVHHDPETMYDVSKALRHTGRRIVLVPTMGALHEGHLTLVRHARKVPGAVVVVSIFVNPLQF
GPGEDLEAYPRTLDSDVAKLREEGVELVFAPNAEAMYPHGRRTTVQPGPLGAELEGASRPTHFAGMLTVVLKLLQIVAPD
RAYFGEKDYQQLVLIRQMVTDLNITTRIVPVPIVREADGLAMSSRNVYLSEEHREQAGALSAALLAGIYSASAGVEAALD
AARAVLDEVPAIEVDYLEVRGADLGPAPAHGPGRMLVAAKLGSTRLLDNVPIEIGPTGPTDPDHELPWRN
>Mature_309_residues
TSLYGPKGPKGYLRGELTVHHDPETMYDVSKALRHTGRRIVLVPTMGALHEGHLTLVRHARKVPGAVVVVSIFVNPLQFG
PGEDLEAYPRTLDSDVAKLREEGVELVFAPNAEAMYPHGRRTTVQPGPLGAELEGASRPTHFAGMLTVVLKLLQIVAPDR
AYFGEKDYQQLVLIRQMVTDLNITTRIVPVPIVREADGLAMSSRNVYLSEEHREQAGALSAALLAGIYSASAGVEAALDA
ARAVLDEVPAIEVDYLEVRGADLGPAPAHGPGRMLVAAKLGSTRLLDNVPIEIGPTGPTDPDHELPWRN

Specific function: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate [H]

COG id: COG0414

COG function: function code H; Panthothenate synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pantothenate synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786325, Length=279, Percent_Identity=46.2365591397849, Blast_Score=216, Evalue=2e-57,
Organism=Saccharomyces cerevisiae, GI6322046, Length=215, Percent_Identity=45.1162790697674, Blast_Score=170, Evalue=2e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003721
- InterPro:   IPR014729 [H]

Pfam domain/function: PF02569 Pantoate_ligase [H]

EC number: =6.3.2.1 [H]

Molecular weight: Translated: 33453; Mature: 33322

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSLYGPKGPKGYLRGELTVHHDPETMYDVSKALRHTGRRIVLVPTMGALHEGHLTLVRH
CCCCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHH
ARKVPGAVVVVSIFVNPLQFGPGEDLEAYPRTLDSDVAKLREEGVELVFAPNAEAMYPHG
HHHCCCCEEEEEEHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCC
RRTTVQPGPLGAELEGASRPTHFAGMLTVVLKLLQIVAPDRAYFGEKDYQQLVLIRQMVT
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHH
DLNITTRIVPVPIVREADGLAMSSRNVYLSEEHREQAGALSAALLAGIYSASAGVEAALD
CCCCEEEEEECCEEECCCCCEECCCCEEECHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
AARAVLDEVPAIEVDYLEVRGADLGPAPAHGPGRMLVAAKLGSTRLLDNVPIEIGPTGPT
HHHHHHHHCCCEEEEEEEEECCCCCCCCCCCCCCEEEEEECCCCCHHCCCCEEECCCCCC
DPDHELPWRN
CCCCCCCCCC
>Mature Secondary Structure 
TSLYGPKGPKGYLRGELTVHHDPETMYDVSKALRHTGRRIVLVPTMGALHEGHLTLVRH
CCCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHH
ARKVPGAVVVVSIFVNPLQFGPGEDLEAYPRTLDSDVAKLREEGVELVFAPNAEAMYPHG
HHHCCCCEEEEEEHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCC
RRTTVQPGPLGAELEGASRPTHFAGMLTVVLKLLQIVAPDRAYFGEKDYQQLVLIRQMVT
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHH
DLNITTRIVPVPIVREADGLAMSSRNVYLSEEHREQAGALSAALLAGIYSASAGVEAALD
CCCCEEEEEECCEEECCCCCEECCCCEEECHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
AARAVLDEVPAIEVDYLEVRGADLGPAPAHGPGRMLVAAKLGSTRLLDNVPIEIGPTGPT
HHHHHHHHCCCEEEEEEEEECCCCCCCCCCCCCCEEEEEECCCCCHHCCCCEEECCCCCC
DPDHELPWRN
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA