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The map label for this gene is yfhM [H]

Identifier: 169627632

GI number: 169627632

Start: 528938

End: 529903

Strand: Reverse

Name: yfhM [H]

Synonym: MAB_0528c

Alternate gene names: 169627632

Gene position: 529903-528938 (Counterclockwise)

Preceding gene: 169627633

Following gene: 169627631

Centisome position: 10.46

GC content: 64.7

Gene sequence:

>966_bases
ATGACCGATGCCGCTGTGGATATCCGGGAACGTGACATCGCCACCAATGGGGTGCACCTGCGCATAGTCGAGGCAGGCGA
GCCCGGCCAACCGGCAGTCATTCTGTCCCACGGGTTCCCCGAGCTGGCATATTCCTGGCGCCATCAGATTCCCGCACTGG
CAGCCGCGGGATACCACGTCATCGCTCCCGATCAGAGGGGCTACGGCAGATCAAGCATGCCCGCGCACATCGATGACTAC
AACATCGAGGCGCTCTCGGATGACCTCCTCGGAATTCTCGATGACGTGGGGGCCGGAAAGGCGACATTCGTCGGACACGA
CTGGGGCGCCGTGGTCACCTGGCATACCGCGCTCGCCGTCCCCGAACGCGTGTCCGGAGTGGTCGGCCTCTCGGTGCCCT
TCACCCGGCGCAGTCAGGTCCCGCCCACACAGGCGTGGAACAAACTGTTCGGCGACAACTTCTTCTACATCCTGTACTTC
CAAGAACCGGGCGTCGCCGACGCCGATCTCAACCGGGACCCGGCAACCACGATGCGCCGCATGATGGCTGGGATGGCCCG
CATCGACGGCGCCACGATGATCGCACCCGGGCCCGCGGGATTCGTTGAGCGCATGCCGGATCCCGGCGAGCTGCCCGAAT
GGCTGAGCCAGGACGAGTTGGACCATTACATCACCGAATTCGCCCGAACCGGATTCACCGGCGGCCTGAACTGGTACCGG
AACTTCGACCGCAATTGGGCTCTCACCGAGCGTCTTGCGGGCGCTAACGTGGTAGTGCCCTCGCTCTTCATCGCGGGCGC
CGCAGATCCGGTACTCGGATTCACCGACCATGCGGGAAGCGCGAAGTACCGGACCGATAACCGGGGCGACCTCCTGATCG
ATGGGGCCGGGCACTGGATCCAGCAAGAGCGGCCGTTGGAGGTCAACGCCGCGCTCCTGGCGTTCCTGCGCGAGGTTGTG
CACTGA

Upstream 100 bases:

>100_bases
GCCGCGGTCCCTGGTCGGGGGATGCGCGTTGTGGTTTAGTGGCAATCACAACGCGCGACGACAAGGCTGTTGGACGCCCC
CGGAAGGTGAGAATGCGCTC

Downstream 100 bases:

>100_bases
TGTCCGCGCCGCCTCTGCGTTTCGGCGCCTTCATCACTCCGTTTCATCCCGTCGGCCAAAATCCCACCACGGCACTGGAA
TACGACCTGGATCGAGTGGT

Product: epoxide hydrolase EphA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 321; Mature: 320

Protein sequence:

>321_residues
MTDAAVDIRERDIATNGVHLRIVEAGEPGQPAVILSHGFPELAYSWRHQIPALAAAGYHVIAPDQRGYGRSSMPAHIDDY
NIEALSDDLLGILDDVGAGKATFVGHDWGAVVTWHTALAVPERVSGVVGLSVPFTRRSQVPPTQAWNKLFGDNFFYILYF
QEPGVADADLNRDPATTMRRMMAGMARIDGATMIAPGPAGFVERMPDPGELPEWLSQDELDHYITEFARTGFTGGLNWYR
NFDRNWALTERLAGANVVVPSLFIAGAADPVLGFTDHAGSAKYRTDNRGDLLIDGAGHWIQQERPLEVNAALLAFLREVV
H

Sequences:

>Translated_321_residues
MTDAAVDIRERDIATNGVHLRIVEAGEPGQPAVILSHGFPELAYSWRHQIPALAAAGYHVIAPDQRGYGRSSMPAHIDDY
NIEALSDDLLGILDDVGAGKATFVGHDWGAVVTWHTALAVPERVSGVVGLSVPFTRRSQVPPTQAWNKLFGDNFFYILYF
QEPGVADADLNRDPATTMRRMMAGMARIDGATMIAPGPAGFVERMPDPGELPEWLSQDELDHYITEFARTGFTGGLNWYR
NFDRNWALTERLAGANVVVPSLFIAGAADPVLGFTDHAGSAKYRTDNRGDLLIDGAGHWIQQERPLEVNAALLAFLREVV
H
>Mature_320_residues
TDAAVDIRERDIATNGVHLRIVEAGEPGQPAVILSHGFPELAYSWRHQIPALAAAGYHVIAPDQRGYGRSSMPAHIDDYN
IEALSDDLLGILDDVGAGKATFVGHDWGAVVTWHTALAVPERVSGVVGLSVPFTRRSQVPPTQAWNKLFGDNFFYILYFQ
EPGVADADLNRDPATTMRRMMAGMARIDGATMIAPGPAGFVERMPDPGELPEWLSQDELDHYITEFARTGFTGGLNWYRN
FDRNWALTERLAGANVVVPSLFIAGAADPVLGFTDHAGSAKYRTDNRGDLLIDGAGHWIQQERPLEVNAALLAFLREVVH

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Epoxide hydrolase family [H]

Homologues:

Organism=Homo sapiens, GI27597073, Length=305, Percent_Identity=37.3770491803279, Blast_Score=215, Evalue=5e-56,
Organism=Homo sapiens, GI218777837, Length=312, Percent_Identity=29.1666666666667, Blast_Score=138, Evalue=6e-33,
Organism=Homo sapiens, GI218777840, Length=312, Percent_Identity=27.5641025641026, Blast_Score=127, Evalue=1e-29,
Organism=Homo sapiens, GI13376164, Length=312, Percent_Identity=27.5641025641026, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17554012, Length=313, Percent_Identity=27.1565495207668, Blast_Score=126, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17562298, Length=312, Percent_Identity=25.6410256410256, Blast_Score=103, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6324392, Length=113, Percent_Identity=33.6283185840708, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: NA

Molecular weight: Translated: 35142; Mature: 35011

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDAAVDIRERDIATNGVHLRIVEAGEPGQPAVILSHGFPELAYSWRHQIPALAAAGYHV
CCCCCCCHHHHCCCCCCEEEEEEECCCCCCCEEEEECCCHHHHHHHHHCCCHHHHCCEEE
IAPDQRGYGRSSMPAHIDDYNIEALSDDLLGILDDVGAGKATFVGHDWGAVVTWHTALAV
ECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEHHHHHC
PERVSGVVGLSVPFTRRSQVPPTQAWNKLFGDNFFYILYFQEPGVADADLNRDPATTMRR
HHHHCCEEEECCCCCCCCCCCHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCHHHHHHH
MMAGMARIDGATMIAPGPAGFVERMPDPGELPEWLSQDELDHYITEFARTGFTGGLNWYR
HHHHHHHCCCCEEECCCCCHHHHCCCCCCCCHHHHCHHHHHHHHHHHHHCCCCCCCHHHH
NFDRNWALTERLAGANVVVPSLFIAGAADPVLGFTDHAGSAKYRTDNRGDLLIDGAGHWI
CCCCCHHHHHHHCCCCEEHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCC
QQERPLEVNAALLAFLREVVH
CCCCCCCHHHHHHHHHHHHHC
>Mature Secondary Structure 
TDAAVDIRERDIATNGVHLRIVEAGEPGQPAVILSHGFPELAYSWRHQIPALAAAGYHV
CCCCCCHHHHCCCCCCEEEEEEECCCCCCCEEEEECCCHHHHHHHHHCCCHHHHCCEEE
IAPDQRGYGRSSMPAHIDDYNIEALSDDLLGILDDVGAGKATFVGHDWGAVVTWHTALAV
ECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEHHHHHC
PERVSGVVGLSVPFTRRSQVPPTQAWNKLFGDNFFYILYFQEPGVADADLNRDPATTMRR
HHHHCCEEEECCCCCCCCCCCHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCHHHHHHH
MMAGMARIDGATMIAPGPAGFVERMPDPGELPEWLSQDELDHYITEFARTGFTGGLNWYR
HHHHHHHCCCCEEECCCCCHHHHCCCCCCCCHHHHCHHHHHHHHHHHHHCCCCCCCHHHH
NFDRNWALTERLAGANVVVPSLFIAGAADPVLGFTDHAGSAKYRTDNRGDLLIDGAGHWI
CCCCCHHHHHHHCCCCEEHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCC
QQERPLEVNAALLAFLREVVH
CCCCCCCHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8946165; 9384377 [H]