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The map label for this gene is espR [H]

Identifier: 169627599

GI number: 169627599

Start: 493989

End: 494411

Strand: Reverse

Name: espR [H]

Synonym: MAB_0495c

Alternate gene names: 169627599

Gene position: 494411-493989 (Counterclockwise)

Preceding gene: 169627600

Following gene: 169627594

Centisome position: 9.76

GC content: 60.99

Gene sequence:

>423_bases
ATGCCGGACTTTTCGAAACGACTGAGCCATCTGTTTGCCACGGTGCATCCGGCAGGGCGTGGCCCGTACTCACTGAACGA
AGTGGTAGCTGCTCTCGGTAAGCGCGGTGTCGAGGTGTCCTCACCGTACCTATCACTCCTGCGCAAGGGCGAGCGTTCCA
ACCCCGCACCGGAAATCGTCACGGCGCTGGCGGAGTTCTTCCAAGTGAGCCCCGCCTACTTCTATGACGCCGACTATGCC
GAATCGGTCAACCGCGACCTGGATTGGCTTGTGCAGCTGCGCGACTCGAAGGTACGAGAGATAGCGCAGCGCAGCTACGC
ATTATCCGAGCACAGCCGGCAGGCGATTGCCGACATGGTCGATCACCTCCGCAAGGTGGAGGGCATACCCGACAAGGAAG
CCGGGAACTCCGCGTCTTCCTGA

Upstream 100 bases:

>100_bases
GCCCGATCACGTGCCCCCGGACGCCCCGGAACCTACGATGAGCAGCACAGCATCGGCGTGTATGGTTGGGCAGCAGAATG
GGAGTACGTGAGGGGGTGCG

Downstream 100 bases:

>100_bases
CGCTCCCGATAGGCGTCGGCTATCGCGAGCATCCAGGATTCGTCACTGACGCCATCAGGGGCGTGCAGCCATTCACGGCT
GAACCCCGGAACTGGTTGGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 140; Mature: 139

Protein sequence:

>140_residues
MPDFSKRLSHLFATVHPAGRGPYSLNEVVAALGKRGVEVSSPYLSLLRKGERSNPAPEIVTALAEFFQVSPAYFYDADYA
ESVNRDLDWLVQLRDSKVREIAQRSYALSEHSRQAIADMVDHLRKVEGIPDKEAGNSASS

Sequences:

>Translated_140_residues
MPDFSKRLSHLFATVHPAGRGPYSLNEVVAALGKRGVEVSSPYLSLLRKGERSNPAPEIVTALAEFFQVSPAYFYDADYA
ESVNRDLDWLVQLRDSKVREIAQRSYALSEHSRQAIADMVDHLRKVEGIPDKEAGNSASS
>Mature_139_residues
PDFSKRLSHLFATVHPAGRGPYSLNEVVAALGKRGVEVSSPYLSLLRKGERSNPAPEIVTALAEFFQVSPAYFYDADYAE
SVNRDLDWLVQLRDSKVREIAQRSYALSEHSRQAIADMVDHLRKVEGIPDKEAGNSASS

Specific function: Required for secretion and virulence in mice. Activates transcription of an operon that includes espA, espC and espD genes, which are ESX-1 components. Acts by binding directly to the promoter region [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted. Note=Probably secreted via the ESX-1 / type VII secretion system (T7SS) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 15536; Mature: 15404

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDFSKRLSHLFATVHPAGRGPYSLNEVVAALGKRGVEVSSPYLSLLRKGERSNPAPEIV
CCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCHHHHH
TALAEFFQVSPAYFYDADYAESVNRDLDWLVQLRDSKVREIAQRSYALSEHSRQAIADMV
HHHHHHHHCCCHHHCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DHLRKVEGIPDKEAGNSASS
HHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
PDFSKRLSHLFATVHPAGRGPYSLNEVVAALGKRGVEVSSPYLSLLRKGERSNPAPEIV
CCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCHHHHH
TALAEFFQVSPAYFYDADYAESVNRDLDWLVQLRDSKVREIAQRSYALSEHSRQAIADMV
HHHHHHHHCCCHHHCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DHLRKVEGIPDKEAGNSASS
HHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]