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The map label for this gene is namA [H]

Identifier: 169627589

GI number: 169627589

Start: 480294

End: 481397

Strand: Direct

Name: namA [H]

Synonym: MAB_0485

Alternate gene names: 169627589

Gene position: 480294-481397 (Clockwise)

Preceding gene: 169627588

Following gene: 169627591

Centisome position: 9.48

GC content: 66.39

Gene sequence:

>1104_bases
ATGAGTCTGTTGTTCGAGCCGTACCGGCTGCGCGACATCACCGTTCCCAATCGGATCTGGATGTCGCCGATGTGTCAATA
TTCGGCGGCCCCGGCCGGGCCGCTGCTCGGCACCCCGAACGATTGGCATCGCACCCACCTGATCAGCCGCGCGATCGGCG
GCGCCGGATTGGTGTTCACCGAGGCCACCTCCGTGAATGCGCAAGGGCGGCTTTCCCCATACGACACCGGTCTCTGGAAC
GACACCCAGGAGCAGGCCTGGGCAGCCATCGTGGACGGTATCAAGCACTTTGGCGCCGTCCCCGCGATACAGCTCGGGCA
TGCCGGGCGCAAGGCATCCACCGTCGCTCCGTGGGACGGGCACCGCTCGCTGGAGCCCACGGACCCGTTGAGTTGGGGGA
CCGTCGGGCCCACCGATGCGCCATACGGTGATTTTGTACCACCCGTGGCCGCCACCACCGCCGACCTCACCGCGATCATC
GAGGACTATGTCAGCGCCGCCCAGCGTGCCCTACGCGCAGGTTTCCAAGTGCTCGAGGTGCACGCTGCCCATGGATACAT
CCAGCACCAGTTCCTTTCTCCGGCAAGCAATACCCGCACCGACGAGTACGGCGGCTCGTTCTCCGGACGGGCCAAACTCA
CTCTCGACACCGTCACGGCGGTCCGCACCGTCTGGCCCGAACACCTACCGTTGTTTGTCAGGGTTTCGGCGACCGATTGG
CTGTCCGAGGAACCGGGACACGAGGCGGACAGCTGGACACCCGATCAGACAGTCGAGCTGGCCAGAATGCTGCAGCCGCG
TGGCGTAGACCTCGTGGACGTGTCGACGGGGGGCAATGTGCCGCACGTGCACATACCCACCGGGCCCGGATACCAGGTGC
GTTTCGCTCGGCGCATTCAGACCGAAACACCGCTTCCCGCAGCGGCAGTGGGCATGATCACGGAGCCGCATCAGGCCGAA
TCCATCCTCGCCGCGGGCGATGCCTCCGCGGTGCTCTTGGGCCGTGAACTATTGCGCGATCCGTACTGGCCGCGGCGGGC
GGCGCGCGAGCTGGGTGCGGATCTGAGCCCCGCGGTGCCCAAGCAGTACGCGCGGGCGTTCTAG

Upstream 100 bases:

>100_bases
GCTGGCTGACCAGCCGGGGAAGCATCCCGGCGATATCTGCGTTGGACTGTGCCGGGCCAGCCATGCTGGCCATCGACCCG
ACGCGAGGAGCCATCGCACC

Downstream 100 bases:

>100_bases
CCCGGCAGTCGCGAGAGCACCAGCCGTAGTACCTTGACGGCAGCGCGCTTGTCCAACGGGGAATTTCCGTTGCCGCACTT
GGGTGATTGCACACATGATG

Product: putative oxidoreductase

Products: NA

Alternate protein names: Xenobiotic reductase [H]

Number of amino acids: Translated: 367; Mature: 366

Protein sequence:

>367_residues
MSLLFEPYRLRDITVPNRIWMSPMCQYSAAPAGPLLGTPNDWHRTHLISRAIGGAGLVFTEATSVNAQGRLSPYDTGLWN
DTQEQAWAAIVDGIKHFGAVPAIQLGHAGRKASTVAPWDGHRSLEPTDPLSWGTVGPTDAPYGDFVPPVAATTADLTAII
EDYVSAAQRALRAGFQVLEVHAAHGYIQHQFLSPASNTRTDEYGGSFSGRAKLTLDTVTAVRTVWPEHLPLFVRVSATDW
LSEEPGHEADSWTPDQTVELARMLQPRGVDLVDVSTGGNVPHVHIPTGPGYQVRFARRIQTETPLPAAAVGMITEPHQAE
SILAAGDASAVLLGRELLRDPYWPRRAARELGADLSPAVPKQYARAF

Sequences:

>Translated_367_residues
MSLLFEPYRLRDITVPNRIWMSPMCQYSAAPAGPLLGTPNDWHRTHLISRAIGGAGLVFTEATSVNAQGRLSPYDTGLWN
DTQEQAWAAIVDGIKHFGAVPAIQLGHAGRKASTVAPWDGHRSLEPTDPLSWGTVGPTDAPYGDFVPPVAATTADLTAII
EDYVSAAQRALRAGFQVLEVHAAHGYIQHQFLSPASNTRTDEYGGSFSGRAKLTLDTVTAVRTVWPEHLPLFVRVSATDW
LSEEPGHEADSWTPDQTVELARMLQPRGVDLVDVSTGGNVPHVHIPTGPGYQVRFARRIQTETPLPAAAVGMITEPHQAE
SILAAGDASAVLLGRELLRDPYWPRRAARELGADLSPAVPKQYARAF
>Mature_366_residues
SLLFEPYRLRDITVPNRIWMSPMCQYSAAPAGPLLGTPNDWHRTHLISRAIGGAGLVFTEATSVNAQGRLSPYDTGLWND
TQEQAWAAIVDGIKHFGAVPAIQLGHAGRKASTVAPWDGHRSLEPTDPLSWGTVGPTDAPYGDFVPPVAATTADLTAIIE
DYVSAAQRALRAGFQVLEVHAAHGYIQHQFLSPASNTRTDEYGGSFSGRAKLTLDTVTAVRTVWPEHLPLFVRVSATDWL
SEEPGHEADSWTPDQTVELARMLQPRGVDLVDVSTGGNVPHVHIPTGPGYQVRFARRIQTETPLPAAAVGMITEPHQAES
ILAAGDASAVLLGRELLRDPYWPRRAARELGADLSPAVPKQYARAF

Specific function: Catalyzes the reduction of the double bond of an array of alpha, beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787939, Length=375, Percent_Identity=29.8666666666667, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1789463, Length=351, Percent_Identity=25.0712250712251, Blast_Score=94, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17565138, Length=282, Percent_Identity=27.6595744680851, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17559802, Length=274, Percent_Identity=29.1970802919708, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17540738, Length=188, Percent_Identity=28.7234042553192, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17566914, Length=374, Percent_Identity=25.9358288770053, Blast_Score=88, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI72001454, Length=287, Percent_Identity=26.4808362369338, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17559804, Length=247, Percent_Identity=25.5060728744939, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17564188, Length=311, Percent_Identity=22.508038585209, Blast_Score=82, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6325086, Length=233, Percent_Identity=31.3304721030043, Blast_Score=99, Evalue=8e-22,
Organism=Saccharomyces cerevisiae, GI6321973, Length=234, Percent_Identity=31.6239316239316, Blast_Score=95, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN [H]

EC number: =1.6.99.1 [H]

Molecular weight: Translated: 39766; Mature: 39635

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: PS00211 ABC_TRANSPORTER_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLLFEPYRLRDITVPNRIWMSPMCQYSAAPAGPLLGTPNDWHRTHLISRAIGGAGLVFT
CCCCCCCCEEEEECCCCHHHHCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEE
EATSVNAQGRLSPYDTGLWNDTQEQAWAAIVDGIKHFGAVPAIQLGHAGRKASTVAPWDG
ECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCC
HRSLEPTDPLSWGTVGPTDAPYGDFVPPVAATTADLTAIIEDYVSAAQRALRAGFQVLEV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEH
HAAHGYIQHQFLSPASNTRTDEYGGSFSGRAKLTLDTVTAVRTVWPEHLPLFVRVSATDW
HHHHCHHHHHHCCCCCCCCCHHCCCCCCCCEEEEHHHHHHHHHHCCCCCCEEEEEECCHH
LSEEPGHEADSWTPDQTVELARMLQPRGVDLVDVSTGGNVPHVHIPTGPGYQVRFARRIQ
CCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCEEECCCCCCCEEEEHHHHC
TETPLPAAAVGMITEPHQAESILAAGDASAVLLGRELLRDPYWPRRAARELGADLSPAVP
CCCCCCHHHHHCCCCCHHHHHEECCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCH
KQYARAF
HHHHHCC
>Mature Secondary Structure 
SLLFEPYRLRDITVPNRIWMSPMCQYSAAPAGPLLGTPNDWHRTHLISRAIGGAGLVFT
CCCCCCCEEEEECCCCHHHHCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEE
EATSVNAQGRLSPYDTGLWNDTQEQAWAAIVDGIKHFGAVPAIQLGHAGRKASTVAPWDG
ECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCC
HRSLEPTDPLSWGTVGPTDAPYGDFVPPVAATTADLTAIIEDYVSAAQRALRAGFQVLEV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEH
HAAHGYIQHQFLSPASNTRTDEYGGSFSGRAKLTLDTVTAVRTVWPEHLPLFVRVSATDW
HHHHCHHHHHHCCCCCCCCCHHCCCCCCCCEEEEHHHHHHHHHHCCCCCCEEEEEECCHH
LSEEPGHEADSWTPDQTVELARMLQPRGVDLVDVSTGGNVPHVHIPTGPGYQVRFARRIQ
CCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCEEECCCCCCCEEEEHHHHC
TETPLPAAAVGMITEPHQAESILAAGDASAVLLGRELLRDPYWPRRAARELGADLSPAVP
CCCCCCHHHHHCCCCCHHHHHEECCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCH
KQYARAF
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]