| Definition | Mycobacterium abscessus ATCC 19977 chromosome chromosome 1, complete sequence. |
|---|---|
| Accession | NC_010397 |
| Length | 5,067,172 |
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The map label for this gene is recD [H]
Identifier: 169627502
GI number: 169627502
Start: 393871
End: 395529
Strand: Reverse
Name: recD [H]
Synonym: MAB_0398c
Alternate gene names: 169627502
Gene position: 395529-393871 (Counterclockwise)
Preceding gene: 169627503
Following gene: 169627501
Centisome position: 7.81
GC content: 68.23
Gene sequence:
>1659_bases ATGAGCTTGGTGGAGGCGTTCGGCGAGATCCTCGAACCCGCGGATGTGCATGTGGCGCAGCGGCTGACGGCGTTGGCATC CGAGACCGATGAGTCGGTGGAGCTGGCAATCGCGCTGGCGGTGCGGGCACTGCGCGGCGGGTCGGTGTGTGTGGATTTGC GCGCGGTGGCGGCGCAGGTGGATATGCCCTCGCTGCCGTGGCCCGCTGCCGATGACTGGCTGGCGGCGGTGCGGGCCAGC CCCTTGGCGGGTGAGCCGCCCGTGCTGCGGCTTTTCGGCGACCTGCTGTACCTCGATCGGTACTGGCGCGAGGAACAACA GGTGTGCACAGATGTGCAAGCGTTGATGGCCGCCGCCCAACCACGCACCGAAGTGCCCACCTATGAGCGACTTTTCCCGC AGGGATTCGAAGAGCAGCGCGCCGCTGCCGATATTGCGCTGTCACAGGGCCTGACCGTGCTGACGGGCGGGCCGGGCACG GGCAAGACCACCACGGTGGCACGGCTGTTGGCGCTGCTGGCCGACCAGGCATCATCGGCGAGCGCCGCGCCGTTGCGTAT CGCGCTGGCAGCACCGACAGGCAAGGCCGCGGCCCGGCTGCAGGAAGCGGTGCAGCTGGAGGTCAACCAGCTGGATGCCG TCGACCGGTCGCGGTTGGCCGGGTTGCAGGCGACCACGCTGCATCGTCTGTTGGGATCGCGCCCCGACACGTCGTCCCGG TTCAAACATGATCGCGGAAACCGGTTGCCGCACGATGTGATTGTGGTGGACGAGACGTCGATGGTGTCGCTGACCATGAT GGCGCGACTGTTGGAGGCGGTGCGCCCGCAGGCCCGACTGCTGCTGGTGGGTGATCCTGATCAGCTGGCCTCGGTGGAGG CGGGCGCGGTGCTGGCCGATCTGGTCGAGGGCCTGGAGTCCGAACGGGTGGCGGCACTGCGCACGTCGCACCGTTTCGGT GCGGCGATTGGCGCGTTGGCGGCGGCGGTGCGTGACGGAGACGCGGATCGCGCGCTAGAGGTGCTGGCATCTGGCGATCC GCATGTGGAGTGGTCGACGGATTCAGAGGGGTTACGCGATGTGCTTGTCCCCCAGGCACTTGCATTGCGTGCGGCAAGCC TGTCCGGTGATGCCACAGCGGCGCTGGCCGTGCTCGACGAGCACCGGATGCTATGCGCGCATCGCCACGGGCCGTTCGGG GTGACGCACTGGAACCGCCAGGTGGAGCGGTGGATCACCGAGGAGACGGGCGAGCCGCACTGGGCACCCTGGTATGCGGG AAGACCGATCCTGGTCACCGCCAATGACTATGGCTTGCGTCTGTACAACGGTGACACCGGCGTGACGGTGGCCGGACCTG ACGGGCTGCGCGCGGTGATCGGCGCAGCATCGTTTGCGACCAGCCGTCTGGTTGAGGTGGAGACCATGCACGCCATGACC ATTCACAAGTCCCAGGGCAGCCAGGCGAATGAAGTGACGGTGCTGCTGCCGTCTGAAGATTCCCGGCTGCTGACACGCGA GCTGTTCTACACGGCGGTCACGCGCGCCAAGCAGCGCGTGCGGGTGGTGGGCTCGGAGGCCGAGGTGCGGGCCGCGATCC AGCGGCAGGCGGTGCGGGCGTCGGGGTTGGGGCGGCGACTGCGCCACAGCCCGAACTGA
Upstream 100 bases:
>100_bases TGTGTGGCGCGACTACCCCGGTGGTAGAGGGGCATCCGGCCGGGGTGTTCAGCTGGCAGCCGCCCTCGGCGCTGGTGGTC GCGCTGTCGGAGCTGCTGTC
Downstream 100 bases:
>100_bases TGTCGACCAATCGATGCATTTGCGAATAGAACAATCACTCATCGAGGCGCGCGTTAGTAGTCCATCCCAACACACATACG ATCTCGCCCATGGCAGACTC
Product: exodeoxyribonuclease V, alpha subunit (RecD)
Products: NA
Alternate protein names: Exodeoxyribonuclease V 67 kDa polypeptide [H]
Number of amino acids: Translated: 552; Mature: 551
Protein sequence:
>552_residues MSLVEAFGEILEPADVHVAQRLTALASETDESVELAIALAVRALRGGSVCVDLRAVAAQVDMPSLPWPAADDWLAAVRAS PLAGEPPVLRLFGDLLYLDRYWREEQQVCTDVQALMAAAQPRTEVPTYERLFPQGFEEQRAAADIALSQGLTVLTGGPGT GKTTTVARLLALLADQASSASAAPLRIALAAPTGKAAARLQEAVQLEVNQLDAVDRSRLAGLQATTLHRLLGSRPDTSSR FKHDRGNRLPHDVIVVDETSMVSLTMMARLLEAVRPQARLLLVGDPDQLASVEAGAVLADLVEGLESERVAALRTSHRFG AAIGALAAAVRDGDADRALEVLASGDPHVEWSTDSEGLRDVLVPQALALRAASLSGDATAALAVLDEHRMLCAHRHGPFG VTHWNRQVERWITEETGEPHWAPWYAGRPILVTANDYGLRLYNGDTGVTVAGPDGLRAVIGAASFATSRLVEVETMHAMT IHKSQGSQANEVTVLLPSEDSRLLTRELFYTAVTRAKQRVRVVGSEAEVRAAIQRQAVRASGLGRRLRHSPN
Sequences:
>Translated_552_residues MSLVEAFGEILEPADVHVAQRLTALASETDESVELAIALAVRALRGGSVCVDLRAVAAQVDMPSLPWPAADDWLAAVRAS PLAGEPPVLRLFGDLLYLDRYWREEQQVCTDVQALMAAAQPRTEVPTYERLFPQGFEEQRAAADIALSQGLTVLTGGPGT GKTTTVARLLALLADQASSASAAPLRIALAAPTGKAAARLQEAVQLEVNQLDAVDRSRLAGLQATTLHRLLGSRPDTSSR FKHDRGNRLPHDVIVVDETSMVSLTMMARLLEAVRPQARLLLVGDPDQLASVEAGAVLADLVEGLESERVAALRTSHRFG AAIGALAAAVRDGDADRALEVLASGDPHVEWSTDSEGLRDVLVPQALALRAASLSGDATAALAVLDEHRMLCAHRHGPFG VTHWNRQVERWITEETGEPHWAPWYAGRPILVTANDYGLRLYNGDTGVTVAGPDGLRAVIGAASFATSRLVEVETMHAMT IHKSQGSQANEVTVLLPSEDSRLLTRELFYTAVTRAKQRVRVVGSEAEVRAAIQRQAVRASGLGRRLRHSPN >Mature_551_residues SLVEAFGEILEPADVHVAQRLTALASETDESVELAIALAVRALRGGSVCVDLRAVAAQVDMPSLPWPAADDWLAAVRASP LAGEPPVLRLFGDLLYLDRYWREEQQVCTDVQALMAAAQPRTEVPTYERLFPQGFEEQRAAADIALSQGLTVLTGGPGTG KTTTVARLLALLADQASSASAAPLRIALAAPTGKAAARLQEAVQLEVNQLDAVDRSRLAGLQATTLHRLLGSRPDTSSRF KHDRGNRLPHDVIVVDETSMVSLTMMARLLEAVRPQARLLLVGDPDQLASVEAGAVLADLVEGLESERVAALRTSHRFGA AIGALAAAVRDGDADRALEVLASGDPHVEWSTDSEGLRDVLVPQALALRAASLSGDATAALAVLDEHRMLCAHRHGPFGV THWNRQVERWITEETGEPHWAPWYAGRPILVTANDYGLRLYNGDTGVTVAGPDGLRAVIGAASFATSRLVEVETMHAMTI HKSQGSQANEVTVLLPSEDSRLLTRELFYTAVTRAKQRVRVVGSEAEVRAAIQRQAVRASGLGRRLRHSPN
Specific function: Exhibits several catalytic activities, including ATP- dependent exonuclease, ATP-stimulated endonuclease, ATP-dependent unwinding and DNA-dependent ATPase activities. Strand cleavage occurs 5' to 3' during the unwinding of duplex DNA at CHI sequences, whi
COG id: COG0507
COG function: function code L; ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the recD family [H]
Homologues:
Organism=Escherichia coli, GI1789182, Length=598, Percent_Identity=36.6220735785953, Blast_Score=260, Evalue=2e-70,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR007807 - InterPro: IPR006344 - InterPro: IPR000606 [H]
Pfam domain/function: PF05127 DUF699; PF01443 Viral_helicase1 [H]
EC number: =3.1.11.5 [H]
Molecular weight: Translated: 59221; Mature: 59090
Theoretical pI: Translated: 5.77; Mature: 5.77
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.5 %Cys (Translated Protein) 1.6 %Met (Translated Protein) 2.2 %Cys+Met (Translated Protein) 0.5 %Cys (Mature Protein) 1.5 %Met (Mature Protein) 2.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSLVEAFGEILEPADVHVAQRLTALASETDESVELAIALAVRALRGGSVCVDLRAVAAQV CCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEHHHHHHHC DMPSLPWPAADDWLAAVRASPLAGEPPVLRLFGDLLYLDRYWREEQQVCTDVQALMAAAQ CCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC PRTEVPTYERLFPQGFEEQRAAADIALSQGLTVLTGGPGTGKTTTVARLLALLADQASSA CCCCCCCHHHHCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCC SAAPLRIALAAPTGKAAARLQEAVQLEVNQLDAVDRSRLAGLQATTLHRLLGSRPDTSSR CCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHH FKHDRGNRLPHDVIVVDETSMVSLTMMARLLEAVRPQARLLLVGDPDQLASVEAGAVLAD HCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHH LVEGLESERVAALRTSHRFGAAIGALAAAVRDGDADRALEVLASGDPHVEWSTDSEGLRD HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEECCCCCCHHH VLVPQALALRAASLSGDATAALAVLDEHRMLCAHRHGPFGVTHWNRQVERWITEETGEPH HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCC WAPWYAGRPILVTANDYGLRLYNGDTGVTVAGPDGLRAVIGAASFATSRLVEVETMHAMT CCCCCCCCEEEEEECCCEEEEEECCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHEEE IHKSQGSQANEVTVLLPSEDSRLLTRELFYTAVTRAKQRVRVVGSEAEVRAAIQRQAVRA EECCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH SGLGRRLRHSPN HHHHHHHCCCCC >Mature Secondary Structure SLVEAFGEILEPADVHVAQRLTALASETDESVELAIALAVRALRGGSVCVDLRAVAAQV CHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEHHHHHHHC DMPSLPWPAADDWLAAVRASPLAGEPPVLRLFGDLLYLDRYWREEQQVCTDVQALMAAAQ CCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC PRTEVPTYERLFPQGFEEQRAAADIALSQGLTVLTGGPGTGKTTTVARLLALLADQASSA CCCCCCCHHHHCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCC SAAPLRIALAAPTGKAAARLQEAVQLEVNQLDAVDRSRLAGLQATTLHRLLGSRPDTSSR CCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHH FKHDRGNRLPHDVIVVDETSMVSLTMMARLLEAVRPQARLLLVGDPDQLASVEAGAVLAD HCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHH LVEGLESERVAALRTSHRFGAAIGALAAAVRDGDADRALEVLASGDPHVEWSTDSEGLRD HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEECCCCCCHHH VLVPQALALRAASLSGDATAALAVLDEHRMLCAHRHGPFGVTHWNRQVERWITEETGEPH HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCC WAPWYAGRPILVTANDYGLRLYNGDTGVTVAGPDGLRAVIGAASFATSRLVEVETMHAMT CCCCCCCCEEEEEECCCEEEEEECCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHEEE IHKSQGSQANEVTVLLPSEDSRLLTRELFYTAVTRAKQRVRVVGSEAEVRAAIQRQAVRA EECCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH SGLGRRLRHSPN HHHHHHHCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 9634230; 12218036 [H]