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The map label for this gene is sufS [H]

Identifier: 169627477

GI number: 169627477

Start: 368939

End: 370021

Strand: Direct

Name: sufS [H]

Synonym: MAB_0373

Alternate gene names: 169627477

Gene position: 368939-370021 (Clockwise)

Preceding gene: 169627476

Following gene: 169627479

Centisome position: 7.28

GC content: 67.41

Gene sequence:

>1083_bases
ATGAGCCTGCGCGACCGGTGGCGGCACGCCCGTCCGCCGGTGCTGGGTGTACACCTCGATTCGGCTGCCTGCTCGCGCCA
GAGTATCGAGACTCTTCGTGCGGTGGCCCAGCACGCCGAGCATGAGGCGCAGATCGGCGGATACGTCGCGCAGGAGGCGG
CGACACCGGTTCTGGAGGCGGGGCGTGCCGCGGTCCGTCAGCTGACGGGTATGCCCGAGGCTCACGTGCAGTTCACCACC
GGAGCGGCCGACGCACTGCGTACACTGTTGCAGGCCTGGCCCGCCGATTCCGGGCGGGTAGTTGCCTGCCTGCCGGGGGA
ATTCGGTCCGAATCTGATGATCATGAACCACTTTGGATTCACCCCGGTGTGGCTGCCGGTCGACGGGGATGGCCGGGCCG
ATGTCGACGGGATCGAGGTGTTTCTTCGGCACGAGAAGATCGACCTGCTGCATCTCACCGTCGTGGGCAGCCACCGCGGC
ACCGTACAGCCTGCCGCCGAGGTGGTGGCGCTGGCGCGCGCGGCCGGGGTGCCCGTCGTCGTCGACGCCGCACAGGCCCT
GGGGCATATCGACTGCACGTATGGGGCGGATGCCATGTATGCACCGTCGCGTAAATGGTTGGCGGGTCCGCGCGGGGTCG
GTGTGCTTGCGGTCAATCCTGTTCTTGAGCACCTGCTTCCGCAGTGGGCGGGCCATGTCGAGGCGCATGTCGCGGGCTGG
GTGGGATTGTCGGTCGCGGTCGGCCAGCATTTGGCCGCGGGCCCGGGGCAGATTCAGGGGGCTTTGGCCGAACGCGGACG
AGCGGCCCGAAAGATACTGGGGGAGTTGAAGGATTGGCGCGTCATCGAATCCGTCGACGAGCCCAGCGCCATCACCACGC
TGGAGCCCGTCGGGGACATCGACGTTATTGCCGTGCGGGCGCGTCTTATCGAGGAACACGCGATCGTGACCACGGGGGCC
GAGATGGTACGTGCACCGTTCGAGATGACCAAGCCGGTGCTGCGGGTCAGTCCGCACGTCGATGGGACCGACGAGGAGCT
GGAACTGCTGGCAGGGGTGCTTGCCTCAGCTCGTCGAGTGTGA

Upstream 100 bases:

>100_bases
GCGAGGGTGTGGCGCGCGAACTGGCCGCCGCGGGCCTGCGACAGACACATTGGTGGACCGACGATGCCGATGATTTCGGG
CTGTCGCTTGCGGTGAAGGA

Downstream 100 bases:

>100_bases
CGGCACGCAGAGGATCTGGCCGAAATGTCTGCGTGGGGTTACATTCGCGTTGTTAGATCAGCTCCCAGGTGTGTACCGGT
TCGTTGGAATGCATGTGCGC

Product: aminotransferase

Products: NA

Alternate protein names: Selenocysteine beta-lyase; SCL; Selenocysteine lyase; Selenocysteine reductase [H]

Number of amino acids: Translated: 360; Mature: 359

Protein sequence:

>360_residues
MSLRDRWRHARPPVLGVHLDSAACSRQSIETLRAVAQHAEHEAQIGGYVAQEAATPVLEAGRAAVRQLTGMPEAHVQFTT
GAADALRTLLQAWPADSGRVVACLPGEFGPNLMIMNHFGFTPVWLPVDGDGRADVDGIEVFLRHEKIDLLHLTVVGSHRG
TVQPAAEVVALARAAGVPVVVDAAQALGHIDCTYGADAMYAPSRKWLAGPRGVGVLAVNPVLEHLLPQWAGHVEAHVAGW
VGLSVAVGQHLAAGPGQIQGALAERGRAARKILGELKDWRVIESVDEPSAITTLEPVGDIDVIAVRARLIEEHAIVTTGA
EMVRAPFEMTKPVLRVSPHVDGTDEELELLAGVLASARRV

Sequences:

>Translated_360_residues
MSLRDRWRHARPPVLGVHLDSAACSRQSIETLRAVAQHAEHEAQIGGYVAQEAATPVLEAGRAAVRQLTGMPEAHVQFTT
GAADALRTLLQAWPADSGRVVACLPGEFGPNLMIMNHFGFTPVWLPVDGDGRADVDGIEVFLRHEKIDLLHLTVVGSHRG
TVQPAAEVVALARAAGVPVVVDAAQALGHIDCTYGADAMYAPSRKWLAGPRGVGVLAVNPVLEHLLPQWAGHVEAHVAGW
VGLSVAVGQHLAAGPGQIQGALAERGRAARKILGELKDWRVIESVDEPSAITTLEPVGDIDVIAVRARLIEEHAIVTTGA
EMVRAPFEMTKPVLRVSPHVDGTDEELELLAGVLASARRV
>Mature_359_residues
SLRDRWRHARPPVLGVHLDSAACSRQSIETLRAVAQHAEHEAQIGGYVAQEAATPVLEAGRAAVRQLTGMPEAHVQFTTG
AADALRTLLQAWPADSGRVVACLPGEFGPNLMIMNHFGFTPVWLPVDGDGRADVDGIEVFLRHEKIDLLHLTVVGSHRGT
VQPAAEVVALARAAGVPVVVDAAQALGHIDCTYGADAMYAPSRKWLAGPRGVGVLAVNPVLEHLLPQWAGHVEAHVAGWV
GLSVAVGQHLAAGPGQIQGALAERGRAARKILGELKDWRVIESVDEPSAITTLEPVGDIDVIAVRARLIEEHAIVTTGAE
MVRAPFEMTKPVLRVSPHVDGTDEELELLAGVLASARRV

Specific function: Cysteine desulfurases mobilize the sulfur from L- cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Component of the suf operon, which is activated and required under speci

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787970, Length=240, Percent_Identity=26.6666666666667, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR010970
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7; =4.4.1.16 [H]

Molecular weight: Translated: 38284; Mature: 38153

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLRDRWRHARPPVLGVHLDSAACSRQSIETLRAVAQHAEHEAQIGGYVAQEAATPVLEA
CCCHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHH
GRAAVRQLTGMPEAHVQFTTGAADALRTLLQAWPADSGRVVACLPGEFGPNLMIMNHFGF
HHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHCCCCCCCEEEEECCCCCCCEEEEECCCC
TPVWLPVDGDGRADVDGIEVFLRHEKIDLLHLTVVGSHRGTVQPAAEVVALARAAGVPVV
CEEEEEECCCCCCCHHHHHHHHHHCCEEEEEEEEEECCCCCCCHHHHHHHHHHHCCCCEE
VDAAQALGHIDCTYGADAMYAPSRKWLAGPRGVGVLAVNPVLEHLLPQWAGHVEAHVAGW
EEHHHHHCCCEECCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHCCHHHHHHHH
VGLSVAVGQHLAAGPGQIQGALAERGRAARKILGELKDWRVIESVDEPSAITTLEPVGDI
HHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHCCHHHHCCCCCCCEEEECCCCCH
DVIAVRARLIEEHAIVTTGAEMVRAPFEMTKPVLRVSPHVDGTDEELELLAGVLASARRV
HHHHHHHHHHHHHHHEECCHHHHHCCHHHCCCCEEECCCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SLRDRWRHARPPVLGVHLDSAACSRQSIETLRAVAQHAEHEAQIGGYVAQEAATPVLEA
CCHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHH
GRAAVRQLTGMPEAHVQFTTGAADALRTLLQAWPADSGRVVACLPGEFGPNLMIMNHFGF
HHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHCCCCCCCEEEEECCCCCCCEEEEECCCC
TPVWLPVDGDGRADVDGIEVFLRHEKIDLLHLTVVGSHRGTVQPAAEVVALARAAGVPVV
CEEEEEECCCCCCCHHHHHHHHHHCCEEEEEEEEEECCCCCCCHHHHHHHHHHHCCCCEE
VDAAQALGHIDCTYGADAMYAPSRKWLAGPRGVGVLAVNPVLEHLLPQWAGHVEAHVAGW
EEHHHHHCCCEECCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHCCHHHHHHHH
VGLSVAVGQHLAAGPGQIQGALAERGRAARKILGELKDWRVIESVDEPSAITTLEPVGDI
HHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHCCHHHHCCCCCCCEEEECCCCCH
DVIAVRARLIEEHAIVTTGAEMVRAPFEMTKPVLRVSPHVDGTDEELELLAGVLASARRV
HHHHHHHHHHHHHHHEECCHHHHHCCHHHCCCCEEECCCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11251816 [H]