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The map label for this gene is nagA [H]

Identifier: 169627466

GI number: 169627466

Start: 358350

End: 359228

Strand: Reverse

Name: nagA [H]

Synonym: MAB_0362c

Alternate gene names: 169627466

Gene position: 359228-358350 (Counterclockwise)

Preceding gene: 169627467

Following gene: 169627461

Centisome position: 7.09

GC content: 67.58

Gene sequence:

>879_bases
ATGTCCGTGACCGCTCCCGGATTTTTCGATATGCACGTACACGGCGGGGGCGGCGCATCATTCGGACGCGACGCCGAGGC
CAATCTGGTTGCCGCCACCTGGCACCGATCACACGGCACCGATGGCTTGCTGGCCAGTCTGGTCACCCTGGCTCCCGATG
ACCTGCTCCGTGCCGTGCGTGTGCTCGCCGAGATGACCGGAGCAGAGGGTATCGCCGGAATTCATCTCGAAGGCCCCTGG
CTGTCCCCACAATATGCCGGGGCACACGACCCGCGGCTGCTTCGCGAACCGGACCTTGGCGAGCTGGAACGGCTGCTCGA
CGCCGGGGGTGGGCACATCAAGATGGTCACCATCGCACCCGAGCTGCCGGGCGCGATATCGGCGATCGAAATGCTCTCGG
GGCGGGGAGTGGTGGCCGCCGTGGGGCATACCAATGCCACCTATGAGCAGACACAACAGGCGATTTCGGCAGGGGCAACC
GTGGCCACCCACCTGTTCAATGCCATGCGGCCGATCCACCACCGCGAGCCGGGCCCCATCCCCGCACTTCTGGAGAGCCC
GGACGTGACCATCGAGCTGATCGCCGACGGGGTGCACATCCATCCCGCGATCTACCGCACGGTGCTGGCCGCGGTCGGCC
CCGACCGGATCGCTCTTGTCACCGATGCGATGTGCGCGGCTGGGATGCCCGACGGGGCCTACCAGCTGGGCGACCTCCCG
GTTACCGTCGCCGGCGGTGAAGCACGGCTGCCCAACGGCACGATCGCGGGCAGCACCGCGAGCATGGCGGATCTACACCG
GTTCGCGGCGGCGCAGGCAGGAACCGATATCGCCACCCGTCAAACATCCGTGAACCCCCGGCGCGCGGTGGGTTGCTAG

Upstream 100 bases:

>100_bases
ATCATTCCGTTGCAACTGCTGGCCATGCAGCTGGCGATCGGCCGCGGCGAAAACCCGGATGTGCCAAGAGGTTTGTCCAA
GGTAACCGAGACACTGTGAA

Downstream 100 bases:

>100_bases
GCGGCGTCGTAGCGGGGGCCGATGATCTTCGCGATCCCCAGCAGACGTTGGTAGCTTTCGGGTCCGGCCGAGCATGCGCG
CAGGTCGGTGGCGGTGTTCC

Product: N-acetylglucosamine-6-phosphate deacetylase NagA

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 292; Mature: 291

Protein sequence:

>292_residues
MSVTAPGFFDMHVHGGGGASFGRDAEANLVAATWHRSHGTDGLLASLVTLAPDDLLRAVRVLAEMTGAEGIAGIHLEGPW
LSPQYAGAHDPRLLREPDLGELERLLDAGGGHIKMVTIAPELPGAISAIEMLSGRGVVAAVGHTNATYEQTQQAISAGAT
VATHLFNAMRPIHHREPGPIPALLESPDVTIELIADGVHIHPAIYRTVLAAVGPDRIALVTDAMCAAGMPDGAYQLGDLP
VTVAGGEARLPNGTIAGSTASMADLHRFAAAQAGTDIATRQTSVNPRRAVGC

Sequences:

>Translated_292_residues
MSVTAPGFFDMHVHGGGGASFGRDAEANLVAATWHRSHGTDGLLASLVTLAPDDLLRAVRVLAEMTGAEGIAGIHLEGPW
LSPQYAGAHDPRLLREPDLGELERLLDAGGGHIKMVTIAPELPGAISAIEMLSGRGVVAAVGHTNATYEQTQQAISAGAT
VATHLFNAMRPIHHREPGPIPALLESPDVTIELIADGVHIHPAIYRTVLAAVGPDRIALVTDAMCAAGMPDGAYQLGDLP
VTVAGGEARLPNGTIAGSTASMADLHRFAAAQAGTDIATRQTSVNPRRAVGC
>Mature_291_residues
SVTAPGFFDMHVHGGGGASFGRDAEANLVAATWHRSHGTDGLLASLVTLAPDDLLRAVRVLAEMTGAEGIAGIHLEGPWL
SPQYAGAHDPRLLREPDLGELERLLDAGGGHIKMVTIAPELPGAISAIEMLSGRGVVAAVGHTNATYEQTQQAISAGATV
ATHLFNAMRPIHHREPGPIPALLESPDVTIELIADGVHIHPAIYRTVLAAVGPDRIALVTDAMCAAGMPDGAYQLGDLPV
TVAGGEARLPNGTIAGSTASMADLHRFAAAQAGTDIATRQTSVNPRRAVGC

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=258, Percent_Identity=36.8217054263566, Blast_Score=132, Evalue=4e-31,
Organism=Homo sapiens, GI224922791, Length=258, Percent_Identity=36.8217054263566, Blast_Score=131, Evalue=8e-31,
Organism=Escherichia coli, GI1786892, Length=299, Percent_Identity=33.4448160535117, Blast_Score=149, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI17553768, Length=279, Percent_Identity=34.0501792114695, Blast_Score=132, Evalue=2e-31,
Organism=Drosophila melanogaster, GI19920392, Length=292, Percent_Identity=36.986301369863, Blast_Score=150, Evalue=7e-37,
Organism=Drosophila melanogaster, GI281361140, Length=305, Percent_Identity=36.3934426229508, Blast_Score=148, Evalue=5e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 30141; Mature: 30009

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVTAPGFFDMHVHGGGGASFGRDAEANLVAATWHRSHGTDGLLASLVTLAPDDLLRAVR
CCCCCCCEEEEEEECCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHCCHHHHHHHH
VLAEMTGAEGIAGIHLEGPWLSPQYAGAHDPRLLREPDLGELERLLDAGGGHIKMVTIAP
HHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEECC
ELPGAISAIEMLSGRGVVAAVGHTNATYEQTQQAISAGATVATHLFNAMRPIHHREPGPI
CCCCHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCC
PALLESPDVTIELIADGVHIHPAIYRTVLAAVGPDRIALVTDAMCAAGMPDGAYQLGDLP
CHHHCCCCCEEEEEECCEEECHHHHHHHHHHCCCCCEEEEHHHHHHCCCCCCCEEECCEE
VTVAGGEARLPNGTIAGSTASMADLHRFAAAQAGTDIATRQTSVNPRRAVGC
EEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHCCCCCCCHHCCCC
>Mature Secondary Structure 
SVTAPGFFDMHVHGGGGASFGRDAEANLVAATWHRSHGTDGLLASLVTLAPDDLLRAVR
CCCCCCEEEEEEECCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHCCHHHHHHHH
VLAEMTGAEGIAGIHLEGPWLSPQYAGAHDPRLLREPDLGELERLLDAGGGHIKMVTIAP
HHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEECC
ELPGAISAIEMLSGRGVVAAVGHTNATYEQTQQAISAGATVATHLFNAMRPIHHREPGPI
CCCCHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCC
PALLESPDVTIELIADGVHIHPAIYRTVLAAVGPDRIALVTDAMCAAGMPDGAYQLGDLP
CHHHCCCCCEEEEEECCEEECHHHHHHHHHHCCCCCEEEEHHHHHHCCCCCCCEEECCEE
VTVAGGEARLPNGTIAGSTASMADLHRFAAAQAGTDIATRQTSVNPRRAVGC
EEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA