Click here to switch to the map view.

The map label for this gene is csd1 [H]

Identifier: 169627322

GI number: 169627322

Start: 227683

End: 229566

Strand: Reverse

Name: csd1 [H]

Synonym: MAB_0217c

Alternate gene names: 169627322

Gene position: 229566-227683 (Counterclockwise)

Preceding gene: 169627323

Following gene: 169627319

Centisome position: 4.53

GC content: 66.72

Gene sequence:

>1884_bases
ATGCCTACAAGTGATGAGATTCCAGTAGCGGACAGCCCGCCGGGATTCCCGTCGTCGGCCGAGCTGGCCGCACTGGCCAC
TCAGCTGTTCTGGGAGGCAACACCTTCCGGAGCGCCTGGTATCGACACCCCGGGACCGGCGGTTCCCGTCGCGCCCCGGG
GCACCGTGCCGGACGCGACGGCGGGTTCCTCCGCGGCAGCCACCACGGGTTCGTGGGCCAGCCCATATGTCCCTGCTCCG
CTGGCCGATGCGCTGTCGACGGCTACGGTGGCCCCGCCGGTAGCAGCCTTCAGCTCGGCCACACCCGATGGCATTCCCGG
TGCCGTGCCGGTAGCTCCGCGCGGTGGTGGCGGCGATCTGAGCTCGGGGACATCTGCGGCACACACCGCCGCAACGGGCT
ATCCGACAACGGGTCTCGCAGATTTCGCCGTCCCCTCCGGACTGGTGCCAACAATCCCGGGCGTGTTGGCGAGCCCGGCC
ACGGCCCCGGTCACAGCATCGCCGCGGACCGCTCCGTATTCGGAGGGGTTGTCGGTACCGGATCTGGGATGGGCTCCCCC
AGCCGCGCCCAGCGGTGGTGACCGGGCTGGTGACGAGGCGAACTACTACTTCCTGGGTGGTGCTCCGGCCGCGGCACCCA
CCCACGAGGACGCACGTGCCTTCGACGTCACCGCCATCCGGGCGGACTTCCCCATCCTGTCCGAGACCGTCAATGGCAAG
CCTCTGATCTGGTTCGACAACGCCGCCACCACGCAGAAGCCCCAGTCCGTGATCGACCGGCTGGTGCACTTCTACCAGCA
TGAGAACTCGAACATCCACCGCGCCGCACATGAGTTGGCGGCACGCGCCACCGACGCGTACGAGGACGCACGCGGAGCGG
CCCGCAAGTTCCTGGGTGCCGAAGCGGACGAGAACATCATCTTCGTGCGCGGCGCCACCGAGGCCATCAATCTGGTGGCC
TATGCCTGGGGCGGCAAGAACCTGGGGCACGGCGACGAGATCGTCATTACCCACCTGGAACACCACGCCAATATCGTTCC
GTGGCAACTGATTGCGCAAAAGACCGGCGCCGTGATCAAGGTGGCCCCGGTGGACGATGCCGGCAACCTGCTGCTCTCCG
AGCTGGAGGATCTGGTTGGACCACGCACCAAACTAGTTGCGGCCACTCAGGTTTCCAACGCGTTGGGAACGGTGACCCCT
GCCAAGCAGATCGTCGAGATCGCACACCGATATGGCGCACGTGTGCTCATCGACGGCGCACAGTCGGTGCCGCATCTGGC
GGTCAACCTGCAGGAGCTCGGCGCCGACTTCTTCGTCTTCTCGGGCCATAAGATCTACGGCCCCACCGGAATCGGCGTGC
TCTATGGCAGCGAAGACGCACTCGCCGAGACGCCACCGTGGCAAGGCGGCGGCAACATGATCGCGGACGTCACCCTACAG
CGTGCGGTGTTCCAGGGCCCGCCGAACAAGTTCGAGGCGGGCACCGGCAACATCGCCGATGCTGTCGGACTGGGTGAAGC
ACTGCGGTACGTGGAGCGGATCGGCATCGACAGGATCGCCGAATACGAGCACGCGCTACTGGAATACGCGACACCGCGGT
TGGCCGCAATCCCGGGCGTGACGCTGGTGGGCACGGCAGATCACAAGGCATCCGTGCTGTCGTTCGTGCTCGACGGGCAT
GATCCGGTGGAAGTCGGGAAGGCCCTGAACGCCGATGGCATCGCGGTGCGCGCCGGACACCACTGCGCGCAGCCGATCCT
GCGTCGGCTGGGCCTGGAGCAGACGGTGCGGCCGTCGTTCGCGTTCTACAACACCTTCGACGAGATCGACGTGTTCATCG
ACGCGGTACGGCGCCTGGCGGAAAGCGGTGGCCCGAAGGCGTAG

Upstream 100 bases:

>100_bases
TCGGCCATCGCCTCGTACCTCGTCACCCTGTATTCGTCGCTGGCTGTGCTGACCGATGACGCACTGGCCGTTCTCGACGA
CGTGCAGGTGGACAAGTTCC

Downstream 100 bases:

>100_bases
TGGGGCAGGCAGCCGGGCGGTTCACCCCGCCCGGCTCACCACCGTCAGCAGTACCACGGAATCCTCGATCGCTGTAAGTT
CGTGGCGCTCTTGCGGAAAG

Product: cysteine desulfurase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 627; Mature: 626

Protein sequence:

>627_residues
MPTSDEIPVADSPPGFPSSAELAALATQLFWEATPSGAPGIDTPGPAVPVAPRGTVPDATAGSSAAATTGSWASPYVPAP
LADALSTATVAPPVAAFSSATPDGIPGAVPVAPRGGGGDLSSGTSAAHTAATGYPTTGLADFAVPSGLVPTIPGVLASPA
TAPVTASPRTAPYSEGLSVPDLGWAPPAAPSGGDRAGDEANYYFLGGAPAAAPTHEDARAFDVTAIRADFPILSETVNGK
PLIWFDNAATTQKPQSVIDRLVHFYQHENSNIHRAAHELAARATDAYEDARGAARKFLGAEADENIIFVRGATEAINLVA
YAWGGKNLGHGDEIVITHLEHHANIVPWQLIAQKTGAVIKVAPVDDAGNLLLSELEDLVGPRTKLVAATQVSNALGTVTP
AKQIVEIAHRYGARVLIDGAQSVPHLAVNLQELGADFFVFSGHKIYGPTGIGVLYGSEDALAETPPWQGGGNMIADVTLQ
RAVFQGPPNKFEAGTGNIADAVGLGEALRYVERIGIDRIAEYEHALLEYATPRLAAIPGVTLVGTADHKASVLSFVLDGH
DPVEVGKALNADGIAVRAGHHCAQPILRRLGLEQTVRPSFAFYNTFDEIDVFIDAVRRLAESGGPKA

Sequences:

>Translated_627_residues
MPTSDEIPVADSPPGFPSSAELAALATQLFWEATPSGAPGIDTPGPAVPVAPRGTVPDATAGSSAAATTGSWASPYVPAP
LADALSTATVAPPVAAFSSATPDGIPGAVPVAPRGGGGDLSSGTSAAHTAATGYPTTGLADFAVPSGLVPTIPGVLASPA
TAPVTASPRTAPYSEGLSVPDLGWAPPAAPSGGDRAGDEANYYFLGGAPAAAPTHEDARAFDVTAIRADFPILSETVNGK
PLIWFDNAATTQKPQSVIDRLVHFYQHENSNIHRAAHELAARATDAYEDARGAARKFLGAEADENIIFVRGATEAINLVA
YAWGGKNLGHGDEIVITHLEHHANIVPWQLIAQKTGAVIKVAPVDDAGNLLLSELEDLVGPRTKLVAATQVSNALGTVTP
AKQIVEIAHRYGARVLIDGAQSVPHLAVNLQELGADFFVFSGHKIYGPTGIGVLYGSEDALAETPPWQGGGNMIADVTLQ
RAVFQGPPNKFEAGTGNIADAVGLGEALRYVERIGIDRIAEYEHALLEYATPRLAAIPGVTLVGTADHKASVLSFVLDGH
DPVEVGKALNADGIAVRAGHHCAQPILRRLGLEQTVRPSFAFYNTFDEIDVFIDAVRRLAESGGPKA
>Mature_626_residues
PTSDEIPVADSPPGFPSSAELAALATQLFWEATPSGAPGIDTPGPAVPVAPRGTVPDATAGSSAAATTGSWASPYVPAPL
ADALSTATVAPPVAAFSSATPDGIPGAVPVAPRGGGGDLSSGTSAAHTAATGYPTTGLADFAVPSGLVPTIPGVLASPAT
APVTASPRTAPYSEGLSVPDLGWAPPAAPSGGDRAGDEANYYFLGGAPAAAPTHEDARAFDVTAIRADFPILSETVNGKP
LIWFDNAATTQKPQSVIDRLVHFYQHENSNIHRAAHELAARATDAYEDARGAARKFLGAEADENIIFVRGATEAINLVAY
AWGGKNLGHGDEIVITHLEHHANIVPWQLIAQKTGAVIKVAPVDDAGNLLLSELEDLVGPRTKLVAATQVSNALGTVTPA
KQIVEIAHRYGARVLIDGAQSVPHLAVNLQELGADFFVFSGHKIYGPTGIGVLYGSEDALAETPPWQGGGNMIADVTLQR
AVFQGPPNKFEAGTGNIADAVGLGEALRYVERIGIDRIAEYEHALLEYATPRLAAIPGVTLVGTADHKASVLSFVLDGHD
PVEVGKALNADGIAVRAGHHCAQPILRRLGLEQTVRPSFAFYNTFDEIDVFIDAVRRLAESGGPKA

Specific function: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine [H]

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=403, Percent_Identity=25.5583126550869, Blast_Score=100, Evalue=3e-21,
Organism=Escherichia coli, GI1787970, Length=400, Percent_Identity=47, Blast_Score=389, Evalue=1e-109,
Organism=Escherichia coli, GI1789175, Length=401, Percent_Identity=38.6533665835411, Blast_Score=280, Evalue=2e-76,
Organism=Escherichia coli, GI48994898, Length=394, Percent_Identity=28.6802030456853, Blast_Score=106, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI25143064, Length=400, Percent_Identity=25, Blast_Score=97, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI193211090, Length=369, Percent_Identity=24.9322493224932, Blast_Score=88, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6319831, Length=392, Percent_Identity=27.8061224489796, Blast_Score=115, Evalue=2e-26,
Organism=Drosophila melanogaster, GI20129463, Length=429, Percent_Identity=26.3403263403263, Blast_Score=102, Evalue=6e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR010970
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 64690; Mature: 64559

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
0.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.2 %Met     (Mature Protein)
0.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTSDEIPVADSPPGFPSSAELAALATQLFWEATPSGAPGIDTPGPAVPVAPRGTVPDAT
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AGSSAAATTGSWASPYVPAPLADALSTATVAPPVAAFSSATPDGIPGAVPVAPRGGGGDL
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCC
SSGTSAAHTAATGYPTTGLADFAVPSGLVPTIPGVLASPATAPVTASPRTAPYSEGLSVP
CCCCCHHHHCCCCCCCCCCHHHHCCCCCCCCCCHHHCCCCCCCCCCCCCCCCHHCCCCCC
DLGWAPPAAPSGGDRAGDEANYYFLGGAPAAAPTHEDARAFDVTAIRADFPILSETVNGK
CCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCEEEEEEEECCCCHHHHCCCCC
PLIWFDNAATTQKPQSVIDRLVHFYQHENSNIHRAAHELAARATDAYEDARGAARKFLGA
EEEEECCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EADENIIFVRGATEAINLVAYAWGGKNLGHGDEIVITHLEHHANIVPWQLIAQKTGAVIK
CCCCCEEEEECCHHHEEEEEEECCCCCCCCCCCEEEEEEHHCCCCCHHHHHHHCCCCEEE
VAPVDDAGNLLLSELEDLVGPRTKLVAATQVSNALGTVTPAKQIVEIAHRYGARVLIDGA
EEECCCCHHHHHHHHHHHHCCCHHEEEHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEECC
QSVPHLAVNLQELGADFFVFSGHKIYGPTGIGVLYGSEDALAETPPWQGGGNMIADVTLQ
CCCCHHEEEHHHCCCCEEEEECCEEECCCCEEEEECCCCCCCCCCCCCCCCCEEHHHHHH
RAVFQGPPNKFEAGTGNIADAVGLGEALRYVERIGIDRIAEYEHALLEYATPRLAAIPGV
HHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCHHHCCCE
TLVGTADHKASVLSFVLDGHDPVEVGKALNADGIAVRAGHHCAQPILRRLGLEQTVRPSF
EEEECCCHHHHHHHHHHCCCCHHHHHHHCCCCCEEEECCCHHHHHHHHHCCCCHHCCCCC
AFYNTFDEIDVFIDAVRRLAESGGPKA
HHHCCHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
PTSDEIPVADSPPGFPSSAELAALATQLFWEATPSGAPGIDTPGPAVPVAPRGTVPDAT
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AGSSAAATTGSWASPYVPAPLADALSTATVAPPVAAFSSATPDGIPGAVPVAPRGGGGDL
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCC
SSGTSAAHTAATGYPTTGLADFAVPSGLVPTIPGVLASPATAPVTASPRTAPYSEGLSVP
CCCCCHHHHCCCCCCCCCCHHHHCCCCCCCCCCHHHCCCCCCCCCCCCCCCCHHCCCCCC
DLGWAPPAAPSGGDRAGDEANYYFLGGAPAAAPTHEDARAFDVTAIRADFPILSETVNGK
CCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCEEEEEEEECCCCHHHHCCCCC
PLIWFDNAATTQKPQSVIDRLVHFYQHENSNIHRAAHELAARATDAYEDARGAARKFLGA
EEEEECCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EADENIIFVRGATEAINLVAYAWGGKNLGHGDEIVITHLEHHANIVPWQLIAQKTGAVIK
CCCCCEEEEECCHHHEEEEEEECCCCCCCCCCCEEEEEEHHCCCCCHHHHHHHCCCCEEE
VAPVDDAGNLLLSELEDLVGPRTKLVAATQVSNALGTVTPAKQIVEIAHRYGARVLIDGA
EEECCCCHHHHHHHHHHHHCCCHHEEEHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEECC
QSVPHLAVNLQELGADFFVFSGHKIYGPTGIGVLYGSEDALAETPPWQGGGNMIADVTLQ
CCCCHHEEEHHHCCCCEEEEECCEEECCCCEEEEECCCCCCCCCCCCCCCCCEEHHHHHH
RAVFQGPPNKFEAGTGNIADAVGLGEALRYVERIGIDRIAEYEHALLEYATPRLAAIPGV
HHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCHHHCCCE
TLVGTADHKASVLSFVLDGHDPVEVGKALNADGIAVRAGHHCAQPILRRLGLEQTVRPSF
EEEECCCHHHHHHHHHHCCCCHHHHHHHCCCCCEEEECCCHHHHHHHHHCCCCHHCCCCC
AFYNTFDEIDVFIDAVRRLAESGGPKA
HHHCCHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]