BacMap

Definition	Mycobacterium abscessus ATCC 19977 chromosome chromosome 1, complete sequence.
Accession	NC_010397
Length	5,067,172

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The map label for this gene is ephD [H]

Identifier: 169627249

GI number: 169627249

Start: 141791

End: 142663

Strand: Reverse

Name: ephD [H]

Synonym: MAB_0144c

Alternate gene names: 169627249

Gene position: 142663-141791 (Counterclockwise)

Preceding gene: 169627250

Following gene: 169627248

Centisome position: 2.82

GC content: 65.06

Gene sequence:

>873_bases
ATGCCGGTAGCAGTCGTCACCGGGGCGGGCAGCGGCATCGGGCGTGCGACGGCAGAGCGCTTCGGCCGCAAGGGCTGGAC
CATCGTTGTCTCCGACATCAACGAGGCCACCGGGGCCGAGACCGTCGACCGCATCACCCGAACAGGCGGCAGCGCCGTTT
TCCGTCGCCTGGACGTCGCCGACCTGGAAGACTGGCGGCAATTCACCGACTGGGTGTGCGAGGAACACGGCACTCCCGAT
CTGCTGGTCAACAACGCCGGGATCCTCATCGCCGGTGGATTCCTGGAGCAGACGGGTGCCGATTGGCGTCGCATGATCGC
CATCAACATGATGAGCCCCCTGGTCGGCTCGCGTCTGTTCGTGCAACGCATGGTCGAGGCGGGCGCCCGGGGCCACATCG
CCAACATCTGTTCGGTGGGAGCCTTCATGCCGACTCCACTGGCTCCCTCTTACGTCGTTGCCAAACAAGGCGCTTGGTTC
GGTACCCAGGCACTACGGGCCGAATTCGGTAAGCGCGGCATCGGCGTCAGCGCGATCTGTCCCGGACTGATCGATACCAA
CCTGTCCGCCAACGGAACTCGCAGCGGCGTCGACGAAACGGCCGGCAGCAGTTGGACAGACAAGCTGAATCGCGGTCAGC
ACTTCTTCGGGCGCTCGCCTGACCATGTCGCCGAGGCGGTGGAACGCTCCATGCGCTGGAACCTGTCCACCGTCCCGGTC
GGATTCGAGGCCTGGATCGGGTGGTTCCTCTACCGGCTGTCCCCCGGGCTGATGCGTGGGGCTCTCGGCATCGCACAAAT
GTCGCTGGCCGAACGGGCCGTCGATGTGAGCTCACGGGCACTCACCGCTTTGGGTATCGGAGGAAAACGATGA

Upstream 100 bases:

>100_bases
TTCAGATAATCCTATTATCCGAATGAAGATCTCAACGGAGAGGAAGCCCACGCATGGACACAGCATCGTTCCGGTTTACG
GCGCGCCCGGGAGGTGACTC

Downstream 100 bases:

>100_bases
AGACAGCGATCATCACCGGCGCAGGGTCCGGTATCGGGCGAGAAACCGCACGTCTGTTTGCCTCGCAAGGACACCGGGTT
GTCCTGGCGGATATCGATAT

Product: putative oxidoreductase EphD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 290; Mature: 289

Protein sequence:

>290_residues
MPVAVVTGAGSGIGRATAERFGRKGWTIVVSDINEATGAETVDRITRTGGSAVFRRLDVADLEDWRQFTDWVCEEHGTPD
LLVNNAGILIAGGFLEQTGADWRRMIAINMMSPLVGSRLFVQRMVEAGARGHIANICSVGAFMPTPLAPSYVVAKQGAWF
GTQALRAEFGKRGIGVSAICPGLIDTNLSANGTRSGVDETAGSSWTDKLNRGQHFFGRSPDHVAEAVERSMRWNLSTVPV
GFEAWIGWFLYRLSPGLMRGALGIAQMSLAERAVDVSSRALTALGIGGKR

Sequences:

>Translated_290_residues
MPVAVVTGAGSGIGRATAERFGRKGWTIVVSDINEATGAETVDRITRTGGSAVFRRLDVADLEDWRQFTDWVCEEHGTPD
LLVNNAGILIAGGFLEQTGADWRRMIAINMMSPLVGSRLFVQRMVEAGARGHIANICSVGAFMPTPLAPSYVVAKQGAWF
GTQALRAEFGKRGIGVSAICPGLIDTNLSANGTRSGVDETAGSSWTDKLNRGQHFFGRSPDHVAEAVERSMRWNLSTVPV
GFEAWIGWFLYRLSPGLMRGALGIAQMSLAERAVDVSSRALTALGIGGKR
>Mature_289_residues
PVAVVTGAGSGIGRATAERFGRKGWTIVVSDINEATGAETVDRITRTGGSAVFRRLDVADLEDWRQFTDWVCEEHGTPDL
LVNNAGILIAGGFLEQTGADWRRMIAINMMSPLVGSRLFVQRMVEAGARGHIANICSVGAFMPTPLAPSYVVAKQGAWFG
TQALRAEFGKRGIGVSAICPGLIDTNLSANGTRSGVDETAGSSWTDKLNRGQHFFGRSPDHVAEAVERSMRWNLSTVPVG
FEAWIGWFLYRLSPGLMRGALGIAQMSLAERAVDVSSRALTALGIGGKR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI31542939, Length=190, Percent_Identity=32.1052631578947, Blast_Score=88, Evalue=8e-18,
Organism=Homo sapiens, GI20149619, Length=268, Percent_Identity=27.6119402985075, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI15277342, Length=206, Percent_Identity=30.0970873786408, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI32483357, Length=188, Percent_Identity=30.3191489361702, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI210032110, Length=192, Percent_Identity=27.0833333333333, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI142976729, Length=196, Percent_Identity=25, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI224922801, Length=159, Percent_Identity=32.0754716981132, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI5031737, Length=188, Percent_Identity=29.2553191489362, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI7706318, Length=211, Percent_Identity=27.0142180094787, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI40807363, Length=190, Percent_Identity=28.4210526315789, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI33667109, Length=188, Percent_Identity=29.2553191489362, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI310128830, Length=197, Percent_Identity=25.8883248730964, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI310115468, Length=197, Percent_Identity=25.8883248730964, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI109715829, Length=235, Percent_Identity=27.2340425531915, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI4758504, Length=197, Percent_Identity=30.9644670050761, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI40548397, Length=194, Percent_Identity=30.4123711340206, Blast_Score=65, Evalue=8e-11,
Organism=Homo sapiens, GI214010158, Length=194, Percent_Identity=30.4123711340206, Blast_Score=65, Evalue=8e-11,
Organism=Homo sapiens, GI214010156, Length=194, Percent_Identity=30.4123711340206, Blast_Score=65, Evalue=8e-11,
Organism=Homo sapiens, GI22758144, Length=194, Percent_Identity=30.4123711340206, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI1788459, Length=188, Percent_Identity=29.7872340425532, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1789208, Length=211, Percent_Identity=30.8056872037915, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI87082160, Length=225, Percent_Identity=29.7777777777778, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI1790717, Length=204, Percent_Identity=27.4509803921569, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI2367175, Length=202, Percent_Identity=32.6732673267327, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787905, Length=186, Percent_Identity=33.8709677419355, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1787335, Length=188, Percent_Identity=29.7872340425532, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI87082100, Length=205, Percent_Identity=29.2682926829268, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI2367365, Length=190, Percent_Identity=32.6315789473684, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71994604, Length=232, Percent_Identity=30.6034482758621, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI71994600, Length=233, Percent_Identity=27.4678111587983, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI193203117, Length=186, Percent_Identity=29.0322580645161, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17555706, Length=191, Percent_Identity=28.7958115183246, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI193203115, Length=187, Percent_Identity=28.8770053475936, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17567345, Length=170, Percent_Identity=27.6470588235294, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17564282, Length=187, Percent_Identity=27.2727272727273, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17560676, Length=231, Percent_Identity=28.1385281385281, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17561402, Length=189, Percent_Identity=29.6296296296296, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17508895, Length=187, Percent_Identity=27.807486631016, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI25147288, Length=188, Percent_Identity=28.1914893617021, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17538182, Length=198, Percent_Identity=32.8282828282828, Blast_Score=66, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17555612, Length=204, Percent_Identity=28.4313725490196, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17551412, Length=253, Percent_Identity=26.4822134387352, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17562904, Length=191, Percent_Identity=27.7486910994764, Blast_Score=64, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17559104, Length=192, Percent_Identity=28.6458333333333, Blast_Score=64, Evalue=1e-10,
Organism=Caenorhabditis elegans, GI17563726, Length=190, Percent_Identity=25.7894736842105, Blast_Score=64, Evalue=1e-10,
Organism=Drosophila melanogaster, GI24649181, Length=189, Percent_Identity=32.8042328042328, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI21358495, Length=271, Percent_Identity=27.3062730627306, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI28571526, Length=220, Percent_Identity=29.5454545454545, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24640492, Length=193, Percent_Identity=30.5699481865285, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24639444, Length=191, Percent_Identity=32.4607329842932, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI221510726, Length=245, Percent_Identity=30.2040816326531, Blast_Score=84, Evalue=9e-17,
Organism=Drosophila melanogaster, GI21357041, Length=224, Percent_Identity=28.125, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24580925, Length=194, Percent_Identity=30.4123711340206, Blast_Score=78, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24648944, Length=195, Percent_Identity=31.2820512820513, Blast_Score=78, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24644339, Length=223, Percent_Identity=26.9058295964126, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI23397609, Length=228, Percent_Identity=29.3859649122807, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24584752, Length=263, Percent_Identity=25.4752851711027, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24581726, Length=236, Percent_Identity=29.6610169491525, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI17737361, Length=199, Percent_Identity=29.6482412060301, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24641232, Length=238, Percent_Identity=26.4705882352941, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21355631, Length=170, Percent_Identity=28.2352941176471, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI281364892, Length=194, Percent_Identity=26.2886597938144, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI22024069, Length=205, Percent_Identity=28.2926829268293, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI116007234, Length=207, Percent_Identity=29.951690821256, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00561 Abhydrolase_1; PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 31067; Mature: 30936

Theoretical pI: Translated: 8.91; Mature: 8.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVAVVTGAGSGIGRATAERFGRKGWTIVVSDINEATGAETVDRITRTGGSAVFRRLDVA
CCEEEEECCCCCCHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHCCHHHHHHHCCHH
DLEDWRQFTDWVCEEHGTPDLLVNNAGILIAGGFLEQTGADWRRMIAINMMSPLVGSRLF
HHHHHHHHHHHHHHCCCCCCEEEECCCEEEECCHHHHCCHHHHHHHHHHHHHHHHHHHHH
VQRMVEAGARGHIANICSVGAFMPTPLAPSYVVAKQGAWFGTQALRAEFGKRGIGVSAIC
HHHHHHCCCCCCHHHHHHHCCCCCCCCCCCEEEECCCCCCHHHHHHHHHCCCCCCHHHHC
PGLIDTNLSANGTRSGVDETAGSSWTDKLNRGQHFFGRSPDHVAEAVERSMRWNLSTVPV
CCHHCCCCCCCCCCCCCHHHCCCCHHHHHHCCCHHCCCCHHHHHHHHHHHHHCCCCCCCC
GFEAWIGWFLYRLSPGLMRGALGIAQMSLAERAVDVSSRALTALGIGGKR
CHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
PVAVVTGAGSGIGRATAERFGRKGWTIVVSDINEATGAETVDRITRTGGSAVFRRLDVA
CEEEEECCCCCCHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHCCHHHHHHHCCHH
DLEDWRQFTDWVCEEHGTPDLLVNNAGILIAGGFLEQTGADWRRMIAINMMSPLVGSRLF
HHHHHHHHHHHHHHCCCCCCEEEECCCEEEECCHHHHCCHHHHHHHHHHHHHHHHHHHHH
VQRMVEAGARGHIANICSVGAFMPTPLAPSYVVAKQGAWFGTQALRAEFGKRGIGVSAIC
HHHHHHCCCCCCHHHHHHHCCCCCCCCCCCEEEECCCCCCHHHHHHHHHCCCCCCHHHHC
PGLIDTNLSANGTRSGVDETAGSSWTDKLNRGQHFFGRSPDHVAEAVERSMRWNLSTVPV
CCHHCCCCCCCCCCCCCHHHCCCCHHHHHHCCCHHCCCCHHHHHHHHHHHHHCCCCCCCC
GFEAWIGWFLYRLSPGLMRGALGIAQMSLAERAVDVSSRALTALGIGGKR
CHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]