BacMap

Definition	Mycobacterium abscessus ATCC 19977 chromosome chromosome 1, complete sequence.
Accession	NC_010397
Length	5,067,172

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The map label for this gene is ephD [H]

Identifier: 169627248

GI number: 169627248

Start: 140934

End: 141794

Strand: Reverse

Name: ephD [H]

Synonym: MAB_0143c

Alternate gene names: 169627248

Gene position: 141794-140934 (Counterclockwise)

Preceding gene: 169627249

Following gene: 169627247

Centisome position: 2.8

GC content: 61.44

Gene sequence:

>861_bases
ATGAAGACAGCGATCATCACCGGCGCAGGGTCCGGTATCGGGCGAGAAACCGCACGTCTGTTTGCCTCGCAAGGACACCG
GGTTGTCCTGGCGGATATCGATATCCACGCTGCCGAGGCAGCGACCGACCAGATAGTCGCGGCCGGAGGCAGGGCATCGG
CGTATCAACTGGACGTCGCGGACGAGCAACAGTGGGAGACGTTCGGCAAATGGACCGACTCCGAGTTCGGCCCAGCGGAT
TTGCTTGTCAACAACGCCGGGATCATGGACTGGGGCGGCTTTGTCGACATGACCGCGGAGCAATGGCAGCGCACCATGGA
CATCGACCTGATGAGCGTCATCTACGGCTCACGGATCTTCGCGCAACAGATGATCGATGCGGGTGTCCGCGGACATATCG
TCAACATCTCCTCGGGTGCAGCATTCCTGCCGCACAAGATGATCGCCGCATACGGCACCGCCAAGGCCGCGGTGCTCATG
GCGTCACAATCGCTCCGGGTGGAGCTGCGCCGACATAGGATCGGCGTGAGCGCGATCTGCCCCGGGGTCATCAACACCAA
CCTGATTGCCAACGGCCAGCGCGCCGGGATCAGCGAGGATGACCAGCAGCGGTGGCACGCACAGGCAGGCAAGATCCAGT
CGATCAGTTACGCCGGACCCGACAAAGTGGCGCGCGCCATCGAGCGCTCCGTGCGGCATAACTGGGCCGTTGTTCCCGTC
AATCCCGAGTCCTGGTTCATCTACGGTCTCTACCGGTTGTCACCGAGCTTCAGCCGGACGCTCACCGGTATCGGATCATT
CGAATTGGCTGACGGTTTGATGTCCCGGCTGCAACCTTTACTGAATCGAGTGGCGAAATGA

Upstream 100 bases:

>100_bases
TGATGCGTGGGGCTCTCGGCATCGCACAAATGTCGCTGGCCGAACGGGCCGTCGATGTGAGCTCACGGGCACTCACCGCT
TTGGGTATCGGAGGAAAACG

Downstream 100 bases:

>100_bases
GCAGCGAACAACCAGAATTCGAGGTCGCCGTCATCGGCGCCGGGCCCGGCGGCATTGCAGCCGGGGTCAAGCTGCTGCAG
GCGGGTGTCGGAAACATCGT

Product: putative oxidoreductase EphD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MKTAIITGAGSGIGRETARLFASQGHRVVLADIDIHAAEAATDQIVAAGGRASAYQLDVADEQQWETFGKWTDSEFGPAD
LLVNNAGIMDWGGFVDMTAEQWQRTMDIDLMSVIYGSRIFAQQMIDAGVRGHIVNISSGAAFLPHKMIAAYGTAKAAVLM
ASQSLRVELRRHRIGVSAICPGVINTNLIANGQRAGISEDDQQRWHAQAGKIQSISYAGPDKVARAIERSVRHNWAVVPV
NPESWFIYGLYRLSPSFSRTLTGIGSFELADGLMSRLQPLLNRVAK

Sequences:

>Translated_286_residues
MKTAIITGAGSGIGRETARLFASQGHRVVLADIDIHAAEAATDQIVAAGGRASAYQLDVADEQQWETFGKWTDSEFGPAD
LLVNNAGIMDWGGFVDMTAEQWQRTMDIDLMSVIYGSRIFAQQMIDAGVRGHIVNISSGAAFLPHKMIAAYGTAKAAVLM
ASQSLRVELRRHRIGVSAICPGVINTNLIANGQRAGISEDDQQRWHAQAGKIQSISYAGPDKVARAIERSVRHNWAVVPV
NPESWFIYGLYRLSPSFSRTLTGIGSFELADGLMSRLQPLLNRVAK
>Mature_286_residues
MKTAIITGAGSGIGRETARLFASQGHRVVLADIDIHAAEAATDQIVAAGGRASAYQLDVADEQQWETFGKWTDSEFGPAD
LLVNNAGIMDWGGFVDMTAEQWQRTMDIDLMSVIYGSRIFAQQMIDAGVRGHIVNISSGAAFLPHKMIAAYGTAKAAVLM
ASQSLRVELRRHRIGVSAICPGVINTNLIANGQRAGISEDDQQRWHAQAGKIQSISYAGPDKVARAIERSVRHNWAVVPV
NPESWFIYGLYRLSPSFSRTLTGIGSFELADGLMSRLQPLLNRVAK

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI142976729, Length=190, Percent_Identity=29.4736842105263, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI7705925, Length=187, Percent_Identity=33.1550802139037, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI31542939, Length=196, Percent_Identity=34.1836734693878, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI40807363, Length=189, Percent_Identity=31.2169312169312, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI20149619, Length=206, Percent_Identity=31.0679611650485, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI15277342, Length=193, Percent_Identity=29.0155440414508, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI109715829, Length=233, Percent_Identity=26.1802575107296, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI224922801, Length=169, Percent_Identity=34.3195266272189, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI210032110, Length=193, Percent_Identity=26.9430051813472, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI32483357, Length=188, Percent_Identity=28.1914893617021, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI4758504, Length=197, Percent_Identity=30.4568527918782, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI7706318, Length=191, Percent_Identity=27.2251308900524, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI40254992, Length=187, Percent_Identity=26.7379679144385, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI4557649, Length=188, Percent_Identity=28.1914893617021, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI83715985, Length=167, Percent_Identity=31.1377245508982, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1788459, Length=188, Percent_Identity=34.5744680851064, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI87082100, Length=227, Percent_Identity=33.920704845815, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1790717, Length=187, Percent_Identity=29.4117647058824, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1787905, Length=186, Percent_Identity=36.0215053763441, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1787335, Length=199, Percent_Identity=32.1608040201005, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI2367175, Length=202, Percent_Identity=33.1683168316832, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1789208, Length=186, Percent_Identity=29.0322580645161, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1789057, Length=213, Percent_Identity=26.2910798122066, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787820, Length=188, Percent_Identity=28.7234042553192, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI87082160, Length=187, Percent_Identity=28.3422459893048, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1786812, Length=190, Percent_Identity=30, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1789378, Length=219, Percent_Identity=28.7671232876712, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17564282, Length=263, Percent_Identity=26.9961977186312, Blast_Score=101, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17555706, Length=187, Percent_Identity=33.6898395721925, Blast_Score=101, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI71994604, Length=191, Percent_Identity=32.4607329842932, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17508895, Length=191, Percent_Identity=27.7486910994764, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI193203115, Length=264, Percent_Identity=26.8939393939394, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI193203117, Length=264, Percent_Identity=26.8939393939394, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17567345, Length=169, Percent_Identity=30.7692307692308, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17551412, Length=243, Percent_Identity=31.6872427983539, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI71994600, Length=192, Percent_Identity=29.1666666666667, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17559104, Length=239, Percent_Identity=30.9623430962343, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17562990, Length=195, Percent_Identity=31.7948717948718, Blast_Score=85, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17560332, Length=240, Percent_Identity=31.6666666666667, Blast_Score=85, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17560150, Length=194, Percent_Identity=30.4123711340206, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17562910, Length=235, Percent_Identity=29.7872340425532, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17563726, Length=237, Percent_Identity=28.2700421940928, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17538480, Length=238, Percent_Identity=29.4117647058824, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17560676, Length=232, Percent_Identity=27.5862068965517, Blast_Score=81, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17562906, Length=212, Percent_Identity=28.3018867924528, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI193204405, Length=197, Percent_Identity=31.4720812182741, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI25147288, Length=188, Percent_Identity=30.3191489361702, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17562904, Length=216, Percent_Identity=29.1666666666667, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI72000259, Length=235, Percent_Identity=27.6595744680851, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17538486, Length=238, Percent_Identity=30.672268907563, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17560220, Length=195, Percent_Identity=32.3076923076923, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17531453, Length=197, Percent_Identity=30.9644670050761, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17562908, Length=235, Percent_Identity=27.6595744680851, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17555612, Length=206, Percent_Identity=29.6116504854369, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17565030, Length=238, Percent_Identity=27.7310924369748, Blast_Score=68, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6322861, Length=189, Percent_Identity=31.2169312169312, Blast_Score=77, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6320089, Length=193, Percent_Identity=28.4974093264249, Blast_Score=71, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6322227, Length=192, Percent_Identity=23.4375, Blast_Score=64, Evalue=4e-11,
Organism=Drosophila melanogaster, GI21357041, Length=229, Percent_Identity=31.4410480349345, Blast_Score=95, Evalue=5e-20,
Organism=Drosophila melanogaster, GI28571526, Length=205, Percent_Identity=30.7317073170732, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24649181, Length=190, Percent_Identity=30.5263157894737, Blast_Score=88, Evalue=6e-18,
Organism=Drosophila melanogaster, GI281364892, Length=262, Percent_Identity=28.2442748091603, Blast_Score=87, Evalue=9e-18,
Organism=Drosophila melanogaster, GI23397609, Length=188, Percent_Identity=28.7234042553192, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24581726, Length=244, Percent_Identity=29.9180327868852, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24580925, Length=228, Percent_Identity=30.7017543859649, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI28571387, Length=207, Percent_Identity=29.4685990338164, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24639444, Length=191, Percent_Identity=30.8900523560209, Blast_Score=84, Evalue=8e-17,
Organism=Drosophila melanogaster, GI21355631, Length=171, Percent_Identity=28.6549707602339, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24648944, Length=195, Percent_Identity=28.2051282051282, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24644339, Length=232, Percent_Identity=28.0172413793103, Blast_Score=81, Evalue=7e-16,
Organism=Drosophila melanogaster, GI21358495, Length=271, Percent_Identity=27.6752767527675, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI221510726, Length=282, Percent_Identity=28.0141843971631, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI281364494, Length=200, Percent_Identity=31, Blast_Score=78, Evalue=8e-15,
Organism=Drosophila melanogaster, GI116007234, Length=201, Percent_Identity=30.8457711442786, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24641232, Length=211, Percent_Identity=27.9620853080569, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI17737361, Length=198, Percent_Identity=30.3030303030303, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24584752, Length=189, Percent_Identity=30.1587301587302, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24640492, Length=194, Percent_Identity=27.319587628866, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI116007236, Length=196, Percent_Identity=26.530612244898, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24663911, Length=200, Percent_Identity=28, Blast_Score=68, Evalue=8e-12,
Organism=Drosophila melanogaster, GI18859837, Length=190, Percent_Identity=29.4736842105263, Blast_Score=68, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24641388, Length=210, Percent_Identity=28.5714285714286, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24644337, Length=228, Percent_Identity=28.9473684210526, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00561 Abhydrolase_1; PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 31039; Mature: 31039

Theoretical pI: Translated: 7.80; Mature: 7.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTAIITGAGSGIGRETARLFASQGHRVVLADIDIHAAEAATDQIVAAGGRASAYQLDVA
CCEEEEEECCCCCCHHHHHHHHCCCCEEEEEECCEEHHHHHHHHHEECCCCCCEEEEECC
DEQQWETFGKWTDSEFGPADLLVNNAGIMDWGGFVDMTAEQWQRTMDIDLMSVIYGSRIF
CCHHHHHHCCCCCCCCCCHHEEEECCCCCCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHH
AQQMIDAGVRGHIVNISSGAAFLPHKMIAAYGTAKAAVLMASQSLRVELRRHRIGVSAIC
HHHHHHCCCCEEEEEECCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHC
PGVINTNLIANGQRAGISEDDQQRWHAQAGKIQSISYAGPDKVARAIERSVRHNWAVVPV
CCHHCCCEEECCCCCCCCCHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHCCEEEEEE
NPESWFIYGLYRLSPSFSRTLTGIGSFELADGLMSRLQPLLNRVAK
CCCCEEEEEEEECCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKTAIITGAGSGIGRETARLFASQGHRVVLADIDIHAAEAATDQIVAAGGRASAYQLDVA
CCEEEEEECCCCCCHHHHHHHHCCCCEEEEEECCEEHHHHHHHHHEECCCCCCEEEEECC
DEQQWETFGKWTDSEFGPADLLVNNAGIMDWGGFVDMTAEQWQRTMDIDLMSVIYGSRIF
CCHHHHHHCCCCCCCCCCHHEEEECCCCCCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHH
AQQMIDAGVRGHIVNISSGAAFLPHKMIAAYGTAKAAVLMASQSLRVELRRHRIGVSAIC
HHHHHHCCCCEEEEEECCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHC
PGVINTNLIANGQRAGISEDDQQRWHAQAGKIQSISYAGPDKVARAIERSVRHNWAVVPV
CCHHCCCEEECCCCCCCCCHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHCCEEEEEE
NPESWFIYGLYRLSPSFSRTLTGIGSFELADGLMSRLQPLLNRVAK
CCCCEEEEEEEECCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]