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The map label for this gene is msrR [H]

Identifier: 169627233

GI number: 169627233

Start: 125920

End: 126861

Strand: Reverse

Name: msrR [H]

Synonym: MAB_0128c

Alternate gene names: 169627233

Gene position: 126861-125920 (Counterclockwise)

Preceding gene: 169627234

Following gene: 169627232

Centisome position: 2.5

GC content: 63.69

Gene sequence:

>942_bases
ATGACGCTCATGCTGCTTGGGTTCTGCGGCGTGATCGGTACGGCCCTCTGGCTCGACGGACGGCTACATCACGTCGACGC
GCTCAAGGACTACCCGGATCGTCCGGCGACCGGCAGCGGAACCAACTGGCTTCTGGTCGGCTCCGACAGCCGCCAGGGTC
TCACTCCTGATCAGGAGACCCAGCTGGCCACCGGGGGCGATATCGGCGACGGCCGCACGGACACCATTCTGTTGGTGCAC
ATACCGGCGTTCTACGACGGCGGGGCGGCCACCATGGTGTCGCTGCCCCGAGACTCCTACGTCTCGATCCCCGAGAACGG
CAGCAACAAACTCAATGCCGCGTATTCGCTCGGCGGCCCGGCGCTACTCACCCGAACAGTGGAAGAGGCCACTGGTCTGC
GCATAGATCACTACGCGGAAATCGGGTTCAACGGCTTCGCCTCGGTGGTCGATGCGATCGGCGGTGTCTCGATGTGTCTG
GATGAGCCCATCCAAGACCCCCTGGCCGGTATCGATCTGACGCCGGGTTGCCAGATACTCAACGGGCCCAGTGCACTTGG
GTACGTACGCAGCCGCGCTACGCCCCGGGCAGATCTGGATCGCATGACGCATCAGCGTGCCTTCATGAGCGCACTCTTCC
ACCGGGTGAGTAGTCCGGCAGTGTGGGCCAATCCCTTTCGCTGGTATCCAGTGGCCACATCGACCGCCGACGCGATCACC
CTCGCCGAGGGCGACCACAGCTGGAACCTGGCCCAATTGGGCTGGGCACTAGCAGGTTCCGTGCAGAACTTGACGATGCC
CATCGGATCGTTCTCCGAAAATTGGGCGGGCGACATCGTCACCTGGGATCAGGACGCGTCATCCCGCCTTTTCGACGCCC
TGCGTACCGGCCAACAAATTCCCGCAGACCTCTTACCCGACCCGGCCACACCGACCCCTTGA

Upstream 100 bases:

>100_bases
TACCCGTCCTCGACGGCCACCCGCGGCGCCACCACCACCCACACGCACCCCACGCACGCGGCGCTGGGGTCTGTGGATAC
GGCGCATCGTTGTTTTCGCC

Downstream 100 bases:

>100_bases
CGCACTAGGCTTTTCAAGGTGGCTACCACCGATCTCCATGCGCGTACCTCCTCGCCGTTCCTCGAACTGTTGCACGATCA
AATCCGCAACGAGTTCACTG

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MTLMLLGFCGVIGTALWLDGRLHHVDALKDYPDRPATGSGTNWLLVGSDSRQGLTPDQETQLATGGDIGDGRTDTILLVH
IPAFYDGGAATMVSLPRDSYVSIPENGSNKLNAAYSLGGPALLTRTVEEATGLRIDHYAEIGFNGFASVVDAIGGVSMCL
DEPIQDPLAGIDLTPGCQILNGPSALGYVRSRATPRADLDRMTHQRAFMSALFHRVSSPAVWANPFRWYPVATSTADAIT
LAEGDHSWNLAQLGWALAGSVQNLTMPIGSFSENWAGDIVTWDQDASSRLFDALRTGQQIPADLLPDPATPTP

Sequences:

>Translated_313_residues
MTLMLLGFCGVIGTALWLDGRLHHVDALKDYPDRPATGSGTNWLLVGSDSRQGLTPDQETQLATGGDIGDGRTDTILLVH
IPAFYDGGAATMVSLPRDSYVSIPENGSNKLNAAYSLGGPALLTRTVEEATGLRIDHYAEIGFNGFASVVDAIGGVSMCL
DEPIQDPLAGIDLTPGCQILNGPSALGYVRSRATPRADLDRMTHQRAFMSALFHRVSSPAVWANPFRWYPVATSTADAIT
LAEGDHSWNLAQLGWALAGSVQNLTMPIGSFSENWAGDIVTWDQDASSRLFDALRTGQQIPADLLPDPATPTP
>Mature_312_residues
TLMLLGFCGVIGTALWLDGRLHHVDALKDYPDRPATGSGTNWLLVGSDSRQGLTPDQETQLATGGDIGDGRTDTILLVHI
PAFYDGGAATMVSLPRDSYVSIPENGSNKLNAAYSLGGPALLTRTVEEATGLRIDHYAEIGFNGFASVVDAIGGVSMCLD
EPIQDPLAGIDLTPGCQILNGPSALGYVRSRATPRADLDRMTHQRAFMSALFHRVSSPAVWANPFRWYPVATSTADAITL
AEGDHSWNLAQLGWALAGSVQNLTMPIGSFSENWAGDIVTWDQDASSRLFDALRTGQQIPADLLPDPATPTP

Specific function: Involved in sarA attenuation. Affects resistance to oxacillin and teicoplanin, as well as the synthesis of virulence factors [H]

COG id: COG1316

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the LytR/CpsA/Psr regulatory protein family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004474 [H]

Pfam domain/function: PF03816 LytR_cpsA_psr [H]

EC number: NA

Molecular weight: Translated: 33362; Mature: 33231

Theoretical pI: Translated: 4.40; Mature: 4.40

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLMLLGFCGVIGTALWLDGRLHHVDALKDYPDRPATGSGTNWLLVGSDSRQGLTPDQET
CEEEEHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCCCCCC
QLATGGDIGDGRTDTILLVHIPAFYDGGAATMVSLPRDSYVSIPENGSNKLNAAYSLGGP
EEECCCCCCCCCCCEEEEEEECCEECCCCEEEEECCCCCEEECCCCCCCCEEEEEECCCH
ALLTRTVEEATGLRIDHYAEIGFNGFASVVDAIGGVSMCLDEPIQDPLAGIDLTPGCQIL
HHHHHHHHHHHCCEEEHHHHCCCCHHHHHHHHHCCHHHHHHHHHCCHHHCCCCCCCCEEE
NGPSALGYVRSRATPRADLDRMTHQRAFMSALFHRVSSPAVWANPFRWYPVATSTADAIT
CCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEECCCEEEEEECCCCCCEEE
LAEGDHSWNLAQLGWALAGSVQNLTMPIGSFSENWAGDIVTWDQDASSRLFDALRTGQQI
EECCCCCCCHHHHHHHHHCCCCEEEECCCCCCCCCCCCEEEECCCHHHHHHHHHHCCCCC
PADLLPDPATPTP
CHHHCCCCCCCCC
>Mature Secondary Structure 
TLMLLGFCGVIGTALWLDGRLHHVDALKDYPDRPATGSGTNWLLVGSDSRQGLTPDQET
EEEEHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCCCCCC
QLATGGDIGDGRTDTILLVHIPAFYDGGAATMVSLPRDSYVSIPENGSNKLNAAYSLGGP
EEECCCCCCCCCCCEEEEEEECCEECCCCEEEEECCCCCEEECCCCCCCCEEEEEECCCH
ALLTRTVEEATGLRIDHYAEIGFNGFASVVDAIGGVSMCLDEPIQDPLAGIDLTPGCQIL
HHHHHHHHHHHCCEEEHHHHCCCCHHHHHHHHHCCHHHHHHHHHCCHHHCCCCCCCCEEE
NGPSALGYVRSRATPRADLDRMTHQRAFMSALFHRVSSPAVWANPFRWYPVATSTADAIT
CCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEECCCEEEEEECCCCCCEEE
LAEGDHSWNLAQLGWALAGSVQNLTMPIGSFSENWAGDIVTWDQDASSRLFDALRTGQQI
EECCCCCCCHHHHHHHHHCCCCEEEECCCCCCCCCCCCEEEECCCHHHHHHHHHHCCCCC
PADLLPDPATPTP
CHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12878519 [H]