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The map label for this gene is map [H]

Identifier: 169627199

GI number: 169627199

Start: 95424

End: 96191

Strand: Reverse

Name: map [H]

Synonym: MAB_0094c

Alternate gene names: 169627199

Gene position: 96191-95424 (Counterclockwise)

Preceding gene: 169627210

Following gene: 169627195

Centisome position: 1.9

GC content: 67.32

Gene sequence:

>768_bases
GTGATCGAGCTGAAGTCGCCCGCGGAGATCGGGCGCATGCGCGTGACCGGCGAATTCGTGGCCTCCGTGCTCGCCGAGTT
GTCGTCGTTGGCCGCACCGGGTGTCAATCTGCTCGACCTGGAGCAGCGGGCTCGTGAGATGGTCAGCGACCGCGGCGCCG
TGTCCTGCTACTGGGACTACTCCCCCTCGTTCGGCCGCGGCCCATTCCGCAACGTGATCTGCCTTTCCGTCAATGACGCT
GTGCTGCATGGACTTCCTCACGACTATGTGCTTGCCGACGGCGATCTGTTGAGCATGGACTTTGCGGTGAGCATCGATGG
GTGGGTCGCCGACTCCGCAGTCAGTGTCATCGTCGGGACACCAGAGCCCGAGGATGTCCGACTCATCGACACCACGCGGG
CAGCTCTCGATGCCGCCATTGGCGCGGCCCTCCCGGGTAATCGACTCGGCGATATCTCGGCGGCCGTGGCTGCCGTCGCA
GAGGGCGCCGGGTACCGGATCAACACCGACTTCGGAGGGCACGGCCTGGGCCGCACCATGCACGAGGATCCCCACGTGCC
CAACAAGGGAACGGCCGGCCGGGGGATGAAGCTGGAGCCGGGCCTCACGCTCGCGCTCGAACCATGGTTCGGTCGTGGAA
CCGACCGGCTCACCGTGGACGCGGACGGGTGGACCCTGCGGATGGCGGACGGTTCACGCGGCGCGCACTCCGAGCACACC
ATCGCCATCACCGAGGACGGGCCGCAGGTGCTGACGGTGCAGGGCTAG

Upstream 100 bases:

>100_bases
CGGCGGTGAGCGGCTGACGGACCATGGCGCCGACTCTAGTCTTGGTATTTAAATACCGAAAGCCCTACAGTGGTATTTAA
ATACCGTCAAGGAGGTACAC

Downstream 100 bases:

>100_bases
GCCCACTACGCCGCGCAGCTCTCGCGAAGTACTGGCTGCAACGTCGATAGCGGGACCCTGACCTCGAAGAGTCCGGCTCC
GACCGGACCGAGCCGGACTG

Product: methionine aminopeptidase, type I (MAP)

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MIELKSPAEIGRMRVTGEFVASVLAELSSLAAPGVNLLDLEQRAREMVSDRGAVSCYWDYSPSFGRGPFRNVICLSVNDA
VLHGLPHDYVLADGDLLSMDFAVSIDGWVADSAVSVIVGTPEPEDVRLIDTTRAALDAAIGAALPGNRLGDISAAVAAVA
EGAGYRINTDFGGHGLGRTMHEDPHVPNKGTAGRGMKLEPGLTLALEPWFGRGTDRLTVDADGWTLRMADGSRGAHSEHT
IAITEDGPQVLTVQG

Sequences:

>Translated_255_residues
MIELKSPAEIGRMRVTGEFVASVLAELSSLAAPGVNLLDLEQRAREMVSDRGAVSCYWDYSPSFGRGPFRNVICLSVNDA
VLHGLPHDYVLADGDLLSMDFAVSIDGWVADSAVSVIVGTPEPEDVRLIDTTRAALDAAIGAALPGNRLGDISAAVAAVA
EGAGYRINTDFGGHGLGRTMHEDPHVPNKGTAGRGMKLEPGLTLALEPWFGRGTDRLTVDADGWTLRMADGSRGAHSEHT
IAITEDGPQVLTVQG
>Mature_255_residues
MIELKSPAEIGRMRVTGEFVASVLAELSSLAAPGVNLLDLEQRAREMVSDRGAVSCYWDYSPSFGRGPFRNVICLSVNDA
VLHGLPHDYVLADGDLLSMDFAVSIDGWVADSAVSVIVGTPEPEDVRLIDTTRAALDAAIGAALPGNRLGDISAAVAAVA
EGAGYRINTDFGGHGLGRTMHEDPHVPNKGTAGRGMKLEPGLTLALEPWFGRGTDRLTVDADGWTLRMADGSRGAHSEHT
IAITEDGPQVLTVQG

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI40385867, Length=208, Percent_Identity=29.3269230769231, Blast_Score=112, Evalue=2e-25,
Organism=Homo sapiens, GI164420681, Length=252, Percent_Identity=26.5873015873016, Blast_Score=107, Evalue=1e-23,
Organism=Escherichia coli, GI1786364, Length=255, Percent_Identity=33.3333333333333, Blast_Score=158, Evalue=3e-40,
Organism=Caenorhabditis elegans, GI71996291, Length=253, Percent_Identity=26.8774703557312, Blast_Score=105, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6323273, Length=255, Percent_Identity=25.8823529411765, Blast_Score=107, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24583427, Length=250, Percent_Identity=31.6, Blast_Score=131, Evalue=5e-31,
Organism=Drosophila melanogaster, GI21355531, Length=245, Percent_Identity=29.3877551020408, Blast_Score=110, Evalue=6e-25,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 26887; Mature: 26887

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIELKSPAEIGRMRVTGEFVASVLAELSSLAAPGVNLLDLEQRAREMVSDRGAVSCYWDY
CCCCCCCHHHCEEEECHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHCCCCEEEEECC
SPSFGRGPFRNVICLSVNDAVLHGLPHDYVLADGDLLSMDFAVSIDGWVADSAVSVIVGT
CCCCCCCCCCEEEEEEECHHHHHCCCCCEEEECCCEEEEEEEEEECCEECCCEEEEEECC
PEPEDVRLIDTTRAALDAAIGAALPGNRLGDISAAVAAVAEGAGYRINTDFGGHGLGRTM
CCCCCEEEEEHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCCCCCC
HEDPHVPNKGTAGRGMKLEPGLTLALEPWFGRGTDRLTVDADGWTLRMADGSRGAHSEHT
CCCCCCCCCCCCCCCEEECCCCEEEEECCCCCCCCEEEEECCCEEEEEECCCCCCCCCEE
IAITEDGPQVLTVQG
EEEECCCCEEEEECC
>Mature Secondary Structure
MIELKSPAEIGRMRVTGEFVASVLAELSSLAAPGVNLLDLEQRAREMVSDRGAVSCYWDY
CCCCCCCHHHCEEEECHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHCCCCEEEEECC
SPSFGRGPFRNVICLSVNDAVLHGLPHDYVLADGDLLSMDFAVSIDGWVADSAVSVIVGT
CCCCCCCCCCEEEEEEECHHHHHCCCCCEEEECCCEEEEEEEEEECCEECCCEEEEEECC
PEPEDVRLIDTTRAALDAAIGAALPGNRLGDISAAVAAVAEGAGYRINTDFGGHGLGRTM
CCCCCEEEEEHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCCCCCC
HEDPHVPNKGTAGRGMKLEPGLTLALEPWFGRGTDRLTVDADGWTLRMADGSRGAHSEHT
CCCCCCCCCCCCCCCEEECCCCEEEEECCCCCCCCEEEEECCCEEEEEECCCCCCCCCEE
IAITEDGPQVLTVQG
EEEECCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]