BacMap

Definition	Mycobacterium abscessus ATCC 19977 chromosome chromosome 1, complete sequence.
Accession	NC_010397
Length	5,067,172

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The map label for this gene is ephD [H]

Identifier: 169627195

GI number: 169627195

Start: 86784

End: 87617

Strand: Reverse

Name: ephD [H]

Synonym: MAB_0090c

Alternate gene names: 169627195

Gene position: 87617-86784 (Counterclockwise)

Preceding gene: 169627199

Following gene: 169627194

Centisome position: 1.73

GC content: 66.55

Gene sequence:

>834_bases
ATGACATCCGGCAGTGCCCAGCGCAACAGCCTGGTGGTGGTGACCGGGGCCGGCAGCGGCATCGGCCGCGAGACCTCGCT
GGCCTTCGCCCGCCAGGGCGCCCGTGTCGTGGTCGCCGATATCAACCATGACACCGCCAACGAGACCGTCGGGCTCATCG
AGAAGCTCGGCGGGTCCGCGTACCCGTACGCGCTGGACGTGTCCGACGAGGCGGCGGTGACTGCCTTCGCCGACGATGTG
TGCGCCAAGCACGGCGTGCCCGATGTCCTGATCAACAACGCCGGCGTCGGACACGGCGGCCGGTTCTTCGAGACGTCTTC
CACCGACTTCCAGCGGGTACTCAACATCAACCTGGGCGGAGTGGTCCACGGCTGTCGCGCGTTCGGGCCGCGGATGGCCG
AGCGCAAGAGCGGCCACATCGTGAACATCTCCAGTGCCGCTGCATACACGCCGATCCCCGAGATGGGCGCCTACGCCACC
AGCAAGGCGGCCGTGTTCATGTTCTCCGACGTGCTGCGCGGCGAACTCGCGCGCGACAAGGTGAAGGTGAGCACCATCTG
CCCGGGCATCGTCAACACGAACATCATTCGCACCACCCAGTTCTCGGGCCTCTCGCCGGAGGACGAGGCCAAGCGGCAAC
AGCAGGGAGCGGGCCTGTACGCCAAGCGTGGATACGGCCCGGAGAAGGTCGCCAAGGAAATCGTCAACGCCGTCGCCAAG
GGTAAGTCGGTTGTGCCGGTGACTCCGGAGGCACACGTGCAGTACCACTTCAGCCGCCTGGCCCCGGCGCTGAACAGGTT
CTTCTGGGGCCTCAGCGACAAGATCAGTCGGTAG

Upstream 100 bases:

>100_bases
CTATCCCGTATTGAACGTCACGTCTTTTTCTGCCTGCTCGCAGTGATTTACAATCTCCTTCATCACGTAAGCGCAGCGGT
GCGCAGGATTCGGAGGATGC

Downstream 100 bases:

>100_bases
CAAGAAGGAGATCAGACATCATGGTGCGCAACACAACTGACACCACGGGCGTGCAGGTCGTACCCACCGAGCCGGGCGAG
GTCGTGCTGCGGCCGCGCAA

Product: oxidoreductase EphD

Products: 3alpha12alpha-dihydroxy-oxobeta-cholanate; NADH [C]

Alternate protein names: NA

Number of amino acids: Translated: 277; Mature: 276

Protein sequence:

>277_residues
MTSGSAQRNSLVVVTGAGSGIGRETSLAFARQGARVVVADINHDTANETVGLIEKLGGSAYPYALDVSDEAAVTAFADDV
CAKHGVPDVLINNAGVGHGGRFFETSSTDFQRVLNINLGGVVHGCRAFGPRMAERKSGHIVNISSAAAYTPIPEMGAYAT
SKAAVFMFSDVLRGELARDKVKVSTICPGIVNTNIIRTTQFSGLSPEDEAKRQQQGAGLYAKRGYGPEKVAKEIVNAVAK
GKSVVPVTPEAHVQYHFSRLAPALNRFFWGLSDKISR

Sequences:

>Translated_277_residues
MTSGSAQRNSLVVVTGAGSGIGRETSLAFARQGARVVVADINHDTANETVGLIEKLGGSAYPYALDVSDEAAVTAFADDV
CAKHGVPDVLINNAGVGHGGRFFETSSTDFQRVLNINLGGVVHGCRAFGPRMAERKSGHIVNISSAAAYTPIPEMGAYAT
SKAAVFMFSDVLRGELARDKVKVSTICPGIVNTNIIRTTQFSGLSPEDEAKRQQQGAGLYAKRGYGPEKVAKEIVNAVAK
GKSVVPVTPEAHVQYHFSRLAPALNRFFWGLSDKISR
>Mature_276_residues
TSGSAQRNSLVVVTGAGSGIGRETSLAFARQGARVVVADINHDTANETVGLIEKLGGSAYPYALDVSDEAAVTAFADDVC
AKHGVPDVLINNAGVGHGGRFFETSSTDFQRVLNINLGGVVHGCRAFGPRMAERKSGHIVNISSAAAYTPIPEMGAYATS
KAAVFMFSDVLRGELARDKVKVSTICPGIVNTNIIRTTQFSGLSPEDEAKRQQQGAGLYAKRGYGPEKVAKEIVNAVAKG
KSVVPVTPEAHVQYHFSRLAPALNRFFWGLSDKISR

Specific function: 7-Alpha-Dehydroxylation Of Cholic Acid, Yielding Deoxycholic Acid And Lithocholic Acid, Respectively. Highest Affinity With Taurochenodeoxycholic Acid. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI142976729, Length=227, Percent_Identity=32.5991189427313, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI20149619, Length=274, Percent_Identity=32.8467153284672, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI210032110, Length=207, Percent_Identity=31.4009661835749, Blast_Score=108, Evalue=4e-24,
Organism=Homo sapiens, GI310128830, Length=257, Percent_Identity=29.9610894941634, Blast_Score=106, Evalue=2e-23,
Organism=Homo sapiens, GI310115468, Length=257, Percent_Identity=29.9610894941634, Blast_Score=106, Evalue=2e-23,
Organism=Homo sapiens, GI40807363, Length=207, Percent_Identity=32.3671497584541, Blast_Score=105, Evalue=5e-23,
Organism=Homo sapiens, GI157739938, Length=252, Percent_Identity=29.3650793650794, Blast_Score=95, Evalue=7e-20,
Organism=Homo sapiens, GI66933014, Length=211, Percent_Identity=31.7535545023697, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI25282469, Length=216, Percent_Identity=29.1666666666667, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI109715829, Length=270, Percent_Identity=28.1481481481481, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI40254992, Length=189, Percent_Identity=29.6296296296296, Blast_Score=85, Evalue=8e-17,
Organism=Homo sapiens, GI7706318, Length=199, Percent_Identity=31.6582914572864, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI31543615, Length=226, Percent_Identity=29.646017699115, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI32483357, Length=232, Percent_Identity=26.7241379310345, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI7657478, Length=264, Percent_Identity=28.7878787878788, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI33667109, Length=231, Percent_Identity=28.1385281385281, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI15277342, Length=206, Percent_Identity=30.5825242718447, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI31542939, Length=195, Percent_Identity=29.7435897435897, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI40254986, Length=179, Percent_Identity=29.0502793296089, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI7705855, Length=221, Percent_Identity=28.0542986425339, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI4503817, Length=235, Percent_Identity=28.5106382978723, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI5031737, Length=190, Percent_Identity=30, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI7705925, Length=189, Percent_Identity=31.2169312169312, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI209862901, Length=196, Percent_Identity=31.1224489795918, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI19923983, Length=196, Percent_Identity=31.1224489795918, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI4504505, Length=187, Percent_Identity=31.0160427807487, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI126723750, Length=232, Percent_Identity=25.4310344827586, Blast_Score=71, Evalue=9e-13,
Organism=Homo sapiens, GI150247226, Length=200, Percent_Identity=31, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI4504503, Length=111, Percent_Identity=38.7387387387387, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI44680136, Length=277, Percent_Identity=27.0758122743682, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI44680133, Length=277, Percent_Identity=27.0758122743682, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI17738292, Length=277, Percent_Identity=27.0758122743682, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI19743808, Length=228, Percent_Identity=28.5087719298246, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI186928839, Length=250, Percent_Identity=27.6, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI166795268, Length=215, Percent_Identity=29.3023255813954, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI4758504, Length=198, Percent_Identity=27.7777777777778, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI126723191, Length=190, Percent_Identity=27.3684210526316, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI22507405, Length=188, Percent_Identity=31.9148936170213, Blast_Score=65, Evalue=8e-11,
Organism=Homo sapiens, GI50726952, Length=191, Percent_Identity=29.8429319371728, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI1787905, Length=203, Percent_Identity=36.4532019704434, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI1787820, Length=213, Percent_Identity=32.3943661971831, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI87082100, Length=225, Percent_Identity=32.8888888888889, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1786812, Length=233, Percent_Identity=32.1888412017167, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1787335, Length=229, Percent_Identity=27.5109170305677, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1790717, Length=199, Percent_Identity=28.643216080402, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1786701, Length=259, Percent_Identity=29.3436293436293, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI2367175, Length=243, Percent_Identity=32.0987654320988, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI87082160, Length=188, Percent_Identity=28.1914893617021, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1789378, Length=248, Percent_Identity=28.2258064516129, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789208, Length=183, Percent_Identity=28.9617486338798, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1788459, Length=183, Percent_Identity=25.6830601092896, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1789057, Length=234, Percent_Identity=26.0683760683761, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI193203115, Length=259, Percent_Identity=28.1853281853282, Blast_Score=111, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17564282, Length=204, Percent_Identity=34.3137254901961, Blast_Score=111, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI193203117, Length=204, Percent_Identity=32.3529411764706, Blast_Score=110, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI17508895, Length=191, Percent_Identity=29.3193717277487, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17567345, Length=213, Percent_Identity=31.4553990610329, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI71994604, Length=190, Percent_Identity=32.6315789473684, Blast_Score=98, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI71994600, Length=202, Percent_Identity=31.6831683168317, Blast_Score=94, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17560676, Length=238, Percent_Identity=24.7899159663866, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17555706, Length=189, Percent_Identity=32.2751322751323, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI25147288, Length=187, Percent_Identity=31.5508021390374, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17562904, Length=194, Percent_Identity=31.4432989690722, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17562910, Length=196, Percent_Identity=30.6122448979592, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI71997402, Length=274, Percent_Identity=27.7372262773723, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17544670, Length=193, Percent_Identity=30.0518134715026, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17536651, Length=195, Percent_Identity=30.2564102564103, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI115534694, Length=232, Percent_Identity=28.448275862069, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17565030, Length=217, Percent_Identity=31.3364055299539, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI193204405, Length=191, Percent_Identity=31.413612565445, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17559104, Length=191, Percent_Identity=30.3664921465969, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17536025, Length=234, Percent_Identity=27.7777777777778, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17570069, Length=272, Percent_Identity=26.4705882352941, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17531453, Length=206, Percent_Identity=30.0970873786408, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17563726, Length=241, Percent_Identity=29.4605809128631, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17551412, Length=212, Percent_Identity=27.3584905660377, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI71982365, Length=143, Percent_Identity=34.965034965035, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17560150, Length=192, Percent_Identity=30.7291666666667, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17568967, Length=187, Percent_Identity=28.8770053475936, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17538182, Length=210, Percent_Identity=25.7142857142857, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17562906, Length=189, Percent_Identity=30.6878306878307, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17562990, Length=196, Percent_Identity=30.1020408163265, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17560332, Length=194, Percent_Identity=26.8041237113402, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17538486, Length=213, Percent_Identity=29.5774647887324, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI193210355, Length=190, Percent_Identity=26.3157894736842, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17562908, Length=189, Percent_Identity=30.6878306878307, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17560176, Length=210, Percent_Identity=28.0952380952381, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17561402, Length=210, Percent_Identity=24.7619047619048, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI32563809, Length=198, Percent_Identity=27.7777777777778, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17507613, Length=198, Percent_Identity=27.7777777777778, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17538480, Length=214, Percent_Identity=26.1682242990654, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17560220, Length=189, Percent_Identity=30.1587301587302, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI72000259, Length=240, Percent_Identity=27.9166666666667, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=192, Percent_Identity=29.6875, Blast_Score=84, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6322861, Length=212, Percent_Identity=29.2452830188679, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6320089, Length=195, Percent_Identity=25.6410256410256, Blast_Score=70, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6322227, Length=265, Percent_Identity=25.6603773584906, Blast_Score=68, Evalue=1e-12,
Organism=Drosophila melanogaster, GI281364892, Length=214, Percent_Identity=34.1121495327103, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI21358495, Length=276, Percent_Identity=29.7101449275362, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI21357041, Length=191, Percent_Identity=36.6492146596859, Blast_Score=108, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24640492, Length=241, Percent_Identity=29.4605809128631, Blast_Score=105, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24649181, Length=260, Percent_Identity=30.3846153846154, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI21355631, Length=165, Percent_Identity=35.7575757575758, Blast_Score=104, Evalue=8e-23,
Organism=Drosophila melanogaster, GI28571526, Length=193, Percent_Identity=35.7512953367876, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24581726, Length=273, Percent_Identity=31.1355311355311, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI23397609, Length=189, Percent_Identity=36.5079365079365, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24639444, Length=188, Percent_Identity=33.5106382978723, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI221510726, Length=210, Percent_Identity=31.4285714285714, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24644339, Length=186, Percent_Identity=32.258064516129, Blast_Score=91, Evalue=9e-19,
Organism=Drosophila melanogaster, GI116007236, Length=268, Percent_Identity=29.8507462686567, Blast_Score=88, Evalue=7e-18,
Organism=Drosophila melanogaster, GI17737361, Length=201, Percent_Identity=31.8407960199005, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI161076933, Length=192, Percent_Identity=31.7708333333333, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24584748, Length=192, Percent_Identity=31.7708333333333, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24640442, Length=236, Percent_Identity=28.3898305084746, Blast_Score=78, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24584744, Length=192, Percent_Identity=29.6875, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI281364494, Length=199, Percent_Identity=32.1608040201005, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI28574402, Length=192, Percent_Identity=29.6875, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI116007238, Length=203, Percent_Identity=33.0049261083744, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24641232, Length=200, Percent_Identity=30.5, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI221331218, Length=213, Percent_Identity=29.1079812206573, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24665243, Length=213, Percent_Identity=29.1079812206573, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI28571387, Length=202, Percent_Identity=29.7029702970297, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI21357673, Length=217, Percent_Identity=30.4147465437788, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24663911, Length=217, Percent_Identity=29.4930875576037, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI221331216, Length=214, Percent_Identity=28.9719626168224, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24665247, Length=214, Percent_Identity=28.9719626168224, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24648944, Length=235, Percent_Identity=28.0851063829787, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI18859837, Length=208, Percent_Identity=30.7692307692308, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI116007234, Length=215, Percent_Identity=32.093023255814, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24641388, Length=207, Percent_Identity=31.8840579710145, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24643142, Length=185, Percent_Identity=30.2702702702703, Blast_Score=68, Evalue=8e-12,
Organism=Drosophila melanogaster, GI21356301, Length=252, Percent_Identity=28.5714285714286, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI21355319, Length=195, Percent_Identity=23.5897435897436, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI45553409, Length=204, Percent_Identity=29.9019607843137, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24647948, Length=204, Percent_Identity=29.9019607843137, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24647946, Length=204, Percent_Identity=29.9019607843137, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00561 Abhydrolase_1; PF00106 adh_short [H]

EC number: 1.1.1.159 [C]

Molecular weight: Translated: 29323; Mature: 29192

Theoretical pI: Translated: 9.35; Mature: 9.35

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSGSAQRNSLVVVTGAGSGIGRETSLAFARQGARVVVADINHDTANETVGLIEKLGGSA
CCCCCCCCCCEEEEEECCCCCCCHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHCCCC
YPYALDVSDEAAVTAFADDVCAKHGVPDVLINNAGVGHGGRFFETSSTDFQRVLNINLGG
CCEEEECCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCEEECCCHHHHHHHCCCCCH
VVHGCRAFGPRMAERKSGHIVNISSAAAYTPIPEMGAYATSKAAVFMFSDVLRGELARDK
HHHHHHHHCCHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
VKVSTICPGIVNTNIIRTTQFSGLSPEDEAKRQQQGAGLYAKRGYGPEKVAKEIVNAVAK
EEEEHCCCCHHCCCEEEEEECCCCCCHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHC
GKSVVPVTPEAHVQYHFSRLAPALNRFFWGLSDKISR
CCEEEECCCCHHHHHHHHHHHHHHHHHHHCHHHHCCC
>Mature Secondary Structure 
TSGSAQRNSLVVVTGAGSGIGRETSLAFARQGARVVVADINHDTANETVGLIEKLGGSA
CCCCCCCCCEEEEEECCCCCCCHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHCCCC
YPYALDVSDEAAVTAFADDVCAKHGVPDVLINNAGVGHGGRFFETSSTDFQRVLNINLGG
CCEEEECCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCEEECCCHHHHHHHCCCCCH
VVHGCRAFGPRMAERKSGHIVNISSAAAYTPIPEMGAYATSKAAVFMFSDVLRGELARDK
HHHHHHHHCCHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
VKVSTICPGIVNTNIIRTTQFSGLSPEDEAKRQQQGAGLYAKRGYGPEKVAKEIVNAVAK
EEEEHCCCCHHCCCEEEEEECCCCCCHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHC
GKSVVPVTPEAHVQYHFSRLAPALNRFFWGLSDKISR
CCEEEECCCCHHHHHHHHHHHHHHHHHHHCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: 2-Mercaptoethanol; Dithiothreitol; NAD+; NADH [C]

Metal ions: CaCl2; KCl; MnCl2; NaCl [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 0.8 {cholic} 0.24 {taurochenodeoxycholic} 0.085 {glycochenodeoxycholic} 1 {glycocholic} 0.06 {chenodeoxycholic} [C]

Substrates: @ALPH01.txt*3alpha7alpha12alpha-Trihydroxybeta-cholanate!; NAD [C]

Specific reaction: @ALPH01.txt*3alpha7alpha12alpha-Trihydroxybeta-cholanate! + NAD+ = 3alpha12alpha-dihydroxy-oxobeta-cholanate + NADH [C]

General reaction: Redox reaction [C]

Inhibitor: Ascorbicacid; BaCl2; CoCl2; CuCl2; EDTA; FeCl3; HgCl2; MgCl2; NH4Cl; Potassiumoxalate; Sodiumcitrate; Sodiumlaurylsulfate; Sodiumperchlorate; Sodiumperiodate; Sodiumpersulfate; TritonX-100; Tween; ZnCl2 [C]

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]