Click here to switch to the map view.

The map label for this gene is linC [H]

Identifier: 169627162

GI number: 169627162

Start: 54576

End: 55313

Strand: Direct

Name: linC [H]

Synonym: MAB_0057

Alternate gene names: 169627162

Gene position: 54576-55313 (Clockwise)

Preceding gene: 169627157

Following gene: 169627165

Centisome position: 1.08

GC content: 68.97

Gene sequence:

>738_bases
GTGACAGGGTTCTTGTCCGGCACCGCGTTCGCCGACCGCACCGTCGTGCTCATCGGCGGGGGCACCGGCATTGGTTTGAG
CGTGGCCCGATTGGTGACCGCGGCCGGCGGTGACGTGGTGCTCGGCGGGCGTACACCGGCAACCCTGGCGGTGGCCGCAG
AGGAGCTGGGCGGCAAGGCGCGTTGGCATCTGGTGGACACCGCACACCAGGCGAGCATCGACGCCTTCTTCGACCAGATC
GAGGTGTTGCACGGGTTGTTCACCACGGCCGCGACCTACGTGACCGGTTCGATCGCCGCGCTGTCCGTGGAACAGGCCGC
CACGCCGTTCGAGTCGAAGTTCTGGGGCCAGTACCGCGTGGTGAAGTCCGCGCTCCCCAAGCTGTCCTCCGATGCCTCGG
TGGTGCTGATGTCGGGTGCTGCCAGCGTCCGGCCTGCCGGAAGCGCTCCGGCCTATGTCGCCGCGAACGCGGCCATCGAA
GGCCTGGCGCGCGGGTTGGCCCACGAGCTGGCGCCCATCCGGGTCAACGCGCTCTCCCCTGGCACCGTGGACGGGCACCT
CTGGAATCAGCGCCCGCCCGAGATACGTCGACAGGCTTTCGAGCACATCGCCGCAGCCGCCACCCTGCGCCGACCGGTCA
CGGAAGGTGAAGTCGCCCAGGCCGCGGTGTATCTACTGCTGAACTCCGCGACAACCGGCTCGACGCTGTACACCGACGGC
GGTTACGCGCTGCGTTAG

Upstream 100 bases:

>100_bases
ACGCGTCGCGAAAGGTCACACCGTCGAGGCGCGCGCGCAACTCAGTACGGGACAATTCGGACACTCCAGCAAGGATAGGC
GGTCGGGTAGCTTCGCCCAC

Downstream 100 bases:

>100_bases
ACGCTCCAGGCGCTGGCCAGTCCCGCGGAGACGGAGGCCGCTGCCGTCAACAACCCGTGCCAGGTCTCCGGCTGCAGCTG
TTGAATATCCAACGGGCCCG

Product: putative short chain dehydrogenase/reductase

Products: NA

Alternate protein names: 2,5-DDOL dehydrogenase [H]

Number of amino acids: Translated: 245; Mature: 244

Protein sequence:

>245_residues
MTGFLSGTAFADRTVVLIGGGTGIGLSVARLVTAAGGDVVLGGRTPATLAVAAEELGGKARWHLVDTAHQASIDAFFDQI
EVLHGLFTTAATYVTGSIAALSVEQAATPFESKFWGQYRVVKSALPKLSSDASVVLMSGAASVRPAGSAPAYVAANAAIE
GLARGLAHELAPIRVNALSPGTVDGHLWNQRPPEIRRQAFEHIAAAATLRRPVTEGEVAQAAVYLLLNSATTGSTLYTDG
GYALR

Sequences:

>Translated_245_residues
MTGFLSGTAFADRTVVLIGGGTGIGLSVARLVTAAGGDVVLGGRTPATLAVAAEELGGKARWHLVDTAHQASIDAFFDQI
EVLHGLFTTAATYVTGSIAALSVEQAATPFESKFWGQYRVVKSALPKLSSDASVVLMSGAASVRPAGSAPAYVAANAAIE
GLARGLAHELAPIRVNALSPGTVDGHLWNQRPPEIRRQAFEHIAAAATLRRPVTEGEVAQAAVYLLLNSATTGSTLYTDG
GYALR
>Mature_244_residues
TGFLSGTAFADRTVVLIGGGTGIGLSVARLVTAAGGDVVLGGRTPATLAVAAEELGGKARWHLVDTAHQASIDAFFDQIE
VLHGLFTTAATYVTGSIAALSVEQAATPFESKFWGQYRVVKSALPKLSSDASVVLMSGAASVRPAGSAPAYVAANAAIEG
LARGLAHELAPIRVNALSPGTVDGHLWNQRPPEIRRQAFEHIAAAATLRRPVTEGEVAQAAVYLLLNSATTGSTLYTDGG
YALR

Specific function: Catalyzes the degradation of 2,5-dichloro-2,5- cyclohexadiene-1,4-diol (2,5-DDOL) into 2,5-dichlorohydroquinone (2,5-DCHQ) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI40254992, Length=241, Percent_Identity=26.1410788381743, Blast_Score=68, Evalue=7e-12,
Organism=Escherichia coli, GI87082100, Length=251, Percent_Identity=28.6852589641434, Blast_Score=64, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI115534694, Length=248, Percent_Identity=26.2096774193548, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI28571526, Length=249, Percent_Identity=30.1204819277108, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24643142, Length=247, Percent_Identity=28.3400809716599, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21357041, Length=250, Percent_Identity=27.6, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI23397609, Length=247, Percent_Identity=27.1255060728745, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 25238; Mature: 25107

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGFLSGTAFADRTVVLIGGGTGIGLSVARLVTAAGGDVVLGGRTPATLAVAAEELGGKA
CCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCEEECCCCCCHHEEEHHHHCCCE
RWHLVDTAHQASIDAFFDQIEVLHGLFTTAATYVTGSIAALSVEQAATPFESKFWGQYRV
EEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEHHHHCCCHHHHHHHHHHH
VKSALPKLSSDASVVLMSGAASVRPAGSAPAYVAANAAIEGLARGLAHELAPIRVNALSP
HHHHHCCCCCCCEEEEEECCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHCCCEEEECCCC
GTVDGHLWNQRPPEIRRQAFEHIAAAATLRRPVTEGEVAQAAVYLLLNSATTGSTLYTDG
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHEEECCCCCCEEEECC
GYALR
CEECC
>Mature Secondary Structure 
TGFLSGTAFADRTVVLIGGGTGIGLSVARLVTAAGGDVVLGGRTPATLAVAAEELGGKA
CCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCEEECCCCCCHHEEEHHHHCCCE
RWHLVDTAHQASIDAFFDQIEVLHGLFTTAATYVTGSIAALSVEQAATPFESKFWGQYRV
EEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEHHHHCCCHHHHHHHHHHH
VKSALPKLSSDASVVLMSGAASVRPAGSAPAYVAANAAIEGLARGLAHELAPIRVNALSP
HHHHHCCCCCCCEEEEEECCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHCCCEEEECCCC
GTVDGHLWNQRPPEIRRQAFEHIAAAATLRRPVTEGEVAQAAVYLLLNSATTGSTLYTDG
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHEEECCCCCCEEEECC
GYALR
CEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7515041; 12450824 [H]