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The map label for this gene is ftsW [H]

Identifier: 169627143

GI number: 169627143

Start: 34710

End: 36167

Strand: Reverse

Name: ftsW [H]

Synonym: MAB_0036c

Alternate gene names: 169627143

Gene position: 36167-34710 (Counterclockwise)

Preceding gene: 169627144

Following gene: 169627142

Centisome position: 0.71

GC content: 64.2

Gene sequence:

>1458_bases
ATGACGACGGCGCCCCAAACCGCGGTAGGACCCAGTGGAAGGGGCAGCGGAGCCGTTTCGGCGCCGCCCACTCAATCAAC
ACGACGTAGCGCGGAGCTGGGGCTCCTCGGCTTCGCCGCCGCCATCACCACGGTGGCCCTAGTTCTCGTCGAGGCCAACC
TTGAGCGTGGGTTGTCCTGGGATCTGCTGGGATACGGCTTCGCCTACCTCGTGCTTTTCGTCTTGGCGCACATGGCGGTC
CGTCGCTGGGCTCCGTATGCCGATCCGCTGCTGCTGCCGTGCGTCGCGCTGCTCAACGGACTCGGCCTGGTGATGATCCA
TCGGCTGGATCTCGTGCACTCGTACAACGACGGCGATGCCGATCAGGTCGGTGACAACAACGCTACGCAGCAGATGCTGT
GGACCACGGTCGGCCTGATCGCACTCGCTGCCGTGCTGGCCACCTTGAAGGACCACCGGGTGCTGGCCCGTTACGGCTAT
ACATTCGGGATCGTCGGCTGCGTGCTGCTGGCCATCCCCGCCCTGCTGCCCACATCCATGTCCGAGCAATACGGTGCCAA
GATCTGGATTGAGTTGCCATTCTTGTCGATTCAGCCCGCGGAGGCCGCCAAGATCCTCCTGCTGATCTTCTTCGCCGCAT
TCCTGATGACCAAACGCACGTTGTTCCGCACCGCCGGCCGCAACTATCTGGGCATCGAGCTGCCGCGGCCACGCGACCTG
GGCCCGTTGCTCGCCATCTGGGGAATCTCGGTGGGCGTCATGGTCTTCGAGAAAGACCTCGGAGCCTCACTGCTCTTCTA
CTCGTCGTTTCTCATCGTCCTCTACGTCGCCACCGCCCGAATCAGTTGGGTGCTCATCGGTTTGGCGCTCTTCGCCGCCG
GCAGTGTGATCGCCTACTTCTTGTTCGGTCACGTTCAGGTGCGCGTGCAGAACTGGTGGGATCCGTTCACCGATCCCGAC
GGCGCCGGCTATCAGATGGTCCAATCGCTGTTCAGCTTCGCCACCGGCGGCATTTTCGGCACCGGGCTGGGCAACGGCCA
ACCGGGCACGGTGCCTGCGGCCTCAACCGATTTCATCATCGCCGCGGTGGGTGAGGAACTCGGTTTGGTGGGCCTGGCCG
GGGTGCTCATGCTGTACACGATCGTGATCATCCGCGGGTTCCGTACCGCGCTCGCGGTGCGCGACAGCTTCGGCAAGCTA
CTGGCGGTGGGACTGTCCGCCGCGCTGGCCATGCAGCTGTTCATCGTGGTCGGCGGCGTCACCAAGCTGATCCCACAGAC
CGGTCTGACCACCCCGTGGATGTCGTACGGCGGTTCCTCGCTCATCGCCAACTACGTGCTGCTCGCCATCCTGCTGCGCA
TTTCACATATCGCACGCCGGCCACTGAGTCCACACGCTTCCTCATCGCCCGCCGCCCCGCTCGCGGAGGCCCGCACGGAA
CTGATCGACCGCGTATGA

Upstream 100 bases:

>100_bases
GCCCCGGCGCCAGCACCACGCCAACCACAACATCCACTCCCGCGCCGGCCCCGCTGCCCGCGCCGCCACAAGAGCCGGGT
GTTACCTGCCGGACCGTGTC

Downstream 100 bases:

>100_bases
ACACGTCGATCCGCCGGGTATCGCTGGCTGTCATGGGACTGGTCGTACTGCTGCTGGCCAATGCCACCATCACCCAGGTG
TTTACGGCGCCGGGCCTACG

Product: cell division protein RodA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 485; Mature: 484

Protein sequence:

>485_residues
MTTAPQTAVGPSGRGSGAVSAPPTQSTRRSAELGLLGFAAAITTVALVLVEANLERGLSWDLLGYGFAYLVLFVLAHMAV
RRWAPYADPLLLPCVALLNGLGLVMIHRLDLVHSYNDGDADQVGDNNATQQMLWTTVGLIALAAVLATLKDHRVLARYGY
TFGIVGCVLLAIPALLPTSMSEQYGAKIWIELPFLSIQPAEAAKILLLIFFAAFLMTKRTLFRTAGRNYLGIELPRPRDL
GPLLAIWGISVGVMVFEKDLGASLLFYSSFLIVLYVATARISWVLIGLALFAAGSVIAYFLFGHVQVRVQNWWDPFTDPD
GAGYQMVQSLFSFATGGIFGTGLGNGQPGTVPAASTDFIIAAVGEELGLVGLAGVLMLYTIVIIRGFRTALAVRDSFGKL
LAVGLSAALAMQLFIVVGGVTKLIPQTGLTTPWMSYGGSSLIANYVLLAILLRISHIARRPLSPHASSSPAAPLAEARTE
LIDRV

Sequences:

>Translated_485_residues
MTTAPQTAVGPSGRGSGAVSAPPTQSTRRSAELGLLGFAAAITTVALVLVEANLERGLSWDLLGYGFAYLVLFVLAHMAV
RRWAPYADPLLLPCVALLNGLGLVMIHRLDLVHSYNDGDADQVGDNNATQQMLWTTVGLIALAAVLATLKDHRVLARYGY
TFGIVGCVLLAIPALLPTSMSEQYGAKIWIELPFLSIQPAEAAKILLLIFFAAFLMTKRTLFRTAGRNYLGIELPRPRDL
GPLLAIWGISVGVMVFEKDLGASLLFYSSFLIVLYVATARISWVLIGLALFAAGSVIAYFLFGHVQVRVQNWWDPFTDPD
GAGYQMVQSLFSFATGGIFGTGLGNGQPGTVPAASTDFIIAAVGEELGLVGLAGVLMLYTIVIIRGFRTALAVRDSFGKL
LAVGLSAALAMQLFIVVGGVTKLIPQTGLTTPWMSYGGSSLIANYVLLAILLRISHIARRPLSPHASSSPAAPLAEARTE
LIDRV
>Mature_484_residues
TTAPQTAVGPSGRGSGAVSAPPTQSTRRSAELGLLGFAAAITTVALVLVEANLERGLSWDLLGYGFAYLVLFVLAHMAVR
RWAPYADPLLLPCVALLNGLGLVMIHRLDLVHSYNDGDADQVGDNNATQQMLWTTVGLIALAAVLATLKDHRVLARYGYT
FGIVGCVLLAIPALLPTSMSEQYGAKIWIELPFLSIQPAEAAKILLLIFFAAFLMTKRTLFRTAGRNYLGIELPRPRDLG
PLLAIWGISVGVMVFEKDLGASLLFYSSFLIVLYVATARISWVLIGLALFAAGSVIAYFLFGHVQVRVQNWWDPFTDPDG
AGYQMVQSLFSFATGGIFGTGLGNGQPGTVPAASTDFIIAAVGEELGLVGLAGVLMLYTIVIIRGFRTALAVRDSFGKLL
AVGLSAALAMQLFIVVGGVTKLIPQTGLTTPWMSYGGSSLIANYVLLAILLRISHIARRPLSPHASSSPAAPLAEARTEL
IDRV

Specific function: This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=387, Percent_Identity=29.1989664082687, Blast_Score=140, Evalue=3e-34,
Organism=Escherichia coli, GI1786853, Length=286, Percent_Identity=35.6643356643357, Blast_Score=108, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 51703; Mature: 51572

Theoretical pI: Translated: 8.89; Mature: 8.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTAPQTAVGPSGRGSGAVSAPPTQSTRRSAELGLLGFAAAITTVALVLVEANLERGLSW
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
DLLGYGFAYLVLFVLAHMAVRRWAPYADPLLLPCVALLNGLGLVMIHRLDLVHSYNDGDA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCH
DQVGDNNATQQMLWTTVGLIALAAVLATLKDHRVLARYGYTFGIVGCVLLAIPALLPTSM
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCC
SEQYGAKIWIELPFLSIQPAEAAKILLLIFFAAFLMTKRTLFRTAGRNYLGIELPRPRDL
HHHCCCEEEEEECCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCC
GPLLAIWGISVGVMVFEKDLGASLLFYSSFLIVLYVATARISWVLIGLALFAAGSVIAYF
CHHHHHHHHHHHHHHEEHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFGHVQVRVQNWWDPFTDPDGAGYQMVQSLFSFATGGIFGTGLGNGQPGTVPAASTDFII
HHHHHEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCEEE
AAVGEELGLVGLAGVLMLYTIVIIRGFRTALAVRDSFGKLLAVGLSAALAMQLFIVVGGV
EECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TKLIPQTGLTTPWMSYGGSSLIANYVLLAILLRISHIARRPLSPHASSSPAAPLAEARTE
HHHHCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHH
LIDRV
HHHCC
>Mature Secondary Structure 
TTAPQTAVGPSGRGSGAVSAPPTQSTRRSAELGLLGFAAAITTVALVLVEANLERGLSW
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
DLLGYGFAYLVLFVLAHMAVRRWAPYADPLLLPCVALLNGLGLVMIHRLDLVHSYNDGDA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCH
DQVGDNNATQQMLWTTVGLIALAAVLATLKDHRVLARYGYTFGIVGCVLLAIPALLPTSM
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCC
SEQYGAKIWIELPFLSIQPAEAAKILLLIFFAAFLMTKRTLFRTAGRNYLGIELPRPRDL
HHHCCCEEEEEECCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCC
GPLLAIWGISVGVMVFEKDLGASLLFYSSFLIVLYVATARISWVLIGLALFAAGSVIAYF
CHHHHHHHHHHHHHHEEHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFGHVQVRVQNWWDPFTDPDGAGYQMVQSLFSFATGGIFGTGLGNGQPGTVPAASTDFII
HHHHHEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCEEE
AAVGEELGLVGLAGVLMLYTIVIIRGFRTALAVRDSFGKLLAVGLSAALAMQLFIVVGGV
EECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TKLIPQTGLTTPWMSYGGSSLIANYVLLAILLRISHIARRPLSPHASSSPAAPLAEARTE
HHHHCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHH
LIDRV
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]