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The map label for this gene is trpG [H]

Identifier: 169627139

GI number: 169627139

Start: 29373

End: 30047

Strand: Direct

Name: trpG [H]

Synonym: MAB_0032

Alternate gene names: 169627139

Gene position: 29373-30047 (Clockwise)

Preceding gene: 169627138

Following gene: 169627147

Centisome position: 0.58

GC content: 67.7

Gene sequence:

>675_bases
GTGCGCATCCTGGTCGTCGATAACTACGACAGCTTCGTGTTCAACCTGGTCCAGTATCTGGGCCAGCTCGGCGTGGACGC
GACGGTGTGGCGCAACGACGACCCGCGGCTGGCAGACACCGACGCGGTGGCCGCCGATTTCGACGGTGTGCTGATCAGCC
CAGGACCGGGTACACCCGAGAGCGCGGGCGCGTCGATCGCGATGGTGCATTCCTGCGCGAAGACGGGTACCCCGCTGCTG
GGGGTCTGCCTAGGTCATCAGGCGATCGGGGTGGCGTTCGGCGGCACCGTCGACCGTGCACCGGAGCTGTTGCATGGCAA
GACCAGCACCGTCGAGCACGAGGACGCCGGGGTGCTGCGCGGCCTGCCAAACCCGTTCACCGCCACCAGGTATCACTCAC
TGACCATCCTCCCGGACACGGTGCCCGAGGGTCTGCGGGTGATCGCGCGCACCGCCAGCGGAGTGATCATGGGCGTCATG
CACACCGAGCATCCGATTCACGGGGTGCAGTTCCATCCCGAGTCGATCCTCACCGAAGGCGGGCACCGGATGCTCGCCAA
CTGGCTCACCTATTGCGGGGCACCCCTTGATGAGCCGCTGGTGCGCTCGCTGGAAGCCGAGGTGGCTGCCGCGCTGAACG
GAGTGACCGGACGCGTCGCCGCGCTGGGCGGCTAG

Upstream 100 bases:

>100_bases
TGCGGTGGGCCCCGGGCGTGCCGTCCCGTTACAGGGCCACTGAAGCTCCCGCTGGTCAACCGGCTGGGAAACGGCTGGCG
CGGGTCCGTACCCTTGACCT

Downstream 100 bases:

>100_bases
AACCGTCTAGCCCGCGCCGAAGCGCAGCTTGATCGGGCCGTTGTACCCAACCCCGGCGCCGGCGGGTGGATCCTGGAACA
CCACGCGGGCCCGATTGTTG

Product: para-aminobenzoate synthase component II

Products: NA

Alternate protein names: Anthranilate synthase component II; Glutamine amido-transferase [H]

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MRILVVDNYDSFVFNLVQYLGQLGVDATVWRNDDPRLADTDAVAADFDGVLISPGPGTPESAGASIAMVHSCAKTGTPLL
GVCLGHQAIGVAFGGTVDRAPELLHGKTSTVEHEDAGVLRGLPNPFTATRYHSLTILPDTVPEGLRVIARTASGVIMGVM
HTEHPIHGVQFHPESILTEGGHRMLANWLTYCGAPLDEPLVRSLEAEVAAALNGVTGRVAALGG

Sequences:

>Translated_224_residues
MRILVVDNYDSFVFNLVQYLGQLGVDATVWRNDDPRLADTDAVAADFDGVLISPGPGTPESAGASIAMVHSCAKTGTPLL
GVCLGHQAIGVAFGGTVDRAPELLHGKTSTVEHEDAGVLRGLPNPFTATRYHSLTILPDTVPEGLRVIARTASGVIMGVM
HTEHPIHGVQFHPESILTEGGHRMLANWLTYCGAPLDEPLVRSLEAEVAAALNGVTGRVAALGG
>Mature_224_residues
MRILVVDNYDSFVFNLVQYLGQLGVDATVWRNDDPRLADTDAVAADFDGVLISPGPGTPESAGASIAMVHSCAKTGTPLL
GVCLGHQAIGVAFGGTVDRAPELLHGKTSTVEHEDAGVLRGLPNPFTATRYHSLTILPDTVPEGLRVIARTASGVIMGVM
HTEHPIHGVQFHPESILTEGGHRMLANWLTYCGAPLDEPLVRSLEAEVAAALNGVTGRVAALGG

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI4504035, Length=143, Percent_Identity=30.0699300699301, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1789760, Length=187, Percent_Identity=52.4064171122995, Blast_Score=194, Evalue=4e-51,
Organism=Escherichia coli, GI1787517, Length=208, Percent_Identity=38.9423076923077, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1788854, Length=196, Percent_Identity=27.0408163265306, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1786215, Length=136, Percent_Identity=27.2058823529412, Blast_Score=63, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI133901714, Length=179, Percent_Identity=27.3743016759777, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71992717, Length=174, Percent_Identity=27.5862068965517, Blast_Score=64, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI71992710, Length=174, Percent_Identity=27.5862068965517, Blast_Score=64, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6322638, Length=199, Percent_Identity=41.2060301507538, Blast_Score=165, Evalue=5e-42,
Organism=Saccharomyces cerevisiae, GI6324361, Length=210, Percent_Identity=29.0476190476191, Blast_Score=79, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6324878, Length=167, Percent_Identity=28.1437125748503, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =4.1.3.27 [H]

Molecular weight: Translated: 23504; Mature: 23504

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILVVDNYDSFVFNLVQYLGQLGVDATVWRNDDPRLADTDAVAADFDGVLISPGPGTPE
CEEEEEECCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHCCCCCEEECCCCCCCC
SAGASIAMVHSCAKTGTPLLGVCLGHQAIGVAFGGTVDRAPELLHGKTSTVEHEDAGVLR
CCCCHHHHHHHHHHCCCCHHHHHHCCHHEEEEECCCHHHCHHHHCCCCCCCCCCCCHHHC
GLPNPFTATRYHSLTILPDTVPEGLRVIARTASGVIMGVMHTEHPIHGVQFHPESILTEG
CCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHCCEEEEEEECCCCCCCEEECHHHHHHCC
GHRMLANWLTYCGAPLDEPLVRSLEAEVAAALNGVTGRVAALGG
CHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCC
>Mature Secondary Structure
MRILVVDNYDSFVFNLVQYLGQLGVDATVWRNDDPRLADTDAVAADFDGVLISPGPGTPE
CEEEEEECCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHCCCCCEEECCCCCCCC
SAGASIAMVHSCAKTGTPLLGVCLGHQAIGVAFGGTVDRAPELLHGKTSTVEHEDAGVLR
CCCCHHHHHHHHHHCCCCHHHHHHCCHHEEEEECCCHHHCHHHHCCCCCCCCCCCCHHHC
GLPNPFTATRYHSLTILPDTVPEGLRVIARTASGVIMGVMHTEHPIHGVQFHPESILTEG
CCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHCCEEEEEEECCCCCCCEEECHHHHHHCC
GHRMLANWLTYCGAPLDEPLVRSLEAEVAAALNGVTGRVAALGG
CHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]