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The map label for this gene is rbgA [H]

Identifier: 169834320

GI number: 169834320

Start: 1181025

End: 1181876

Strand: Direct

Name: rbgA [H]

Synonym: SPH_1273

Alternate gene names: 169834320

Gene position: 1181025-1181876 (Clockwise)

Preceding gene: 169832859

Following gene: 169833197

Centisome position: 52.59

GC content: 42.61

Gene sequence:

>852_bases
ATGGCTACTATTCAATGGTTTCCTGGTCACATGTCTAAAGCGCGTCGACAGGTGCAGGAAAATTTAAAATTTGTTGATTT
TGTGACGATTTTAGTGGATGCTCGCTTACCTCTATCTAGTCAAAATCCTATGTTGACCAAGATTGTTGGTGACAAACCAA
AACTCTTGATTTTAAACAAGGCGGACTTGGCTGATCCAGCAATGACCAAGGAATGGCGTCAGTATTTTGAATCACAGGGA
ATCCAGACGCTGGCTATCAACTCCAAAGAACAAGTAACTGTAAAAGTTGTAACCGATGCTGCTAAAAAGCTCATGGCGGA
TAAGATTGCTCGCCAAAAAGAACGTGGGATTCAGATCGAAACCTTGCGTACCATGATTATCGGGATTCCAAACGCTGGTA
AATCAACTCTCATGAATCGTTTGGCCGGCAAGAAGATTGCCGTTGTCGGTAATAAACCAGGTGTGACCAAGGGGCAACAA
TGGCTCAAAACCAATAAAGACTTAGAAATATTGGATACACCGGGGATTCTCTGGCCTAAGTTCGAAGACGAAACTGTCGC
TCTCAAACTAGCCCTAACAGGAGCTATCAAGGACCAGTTGCTTCCTATGGATGAGGTAACCATTTTTGGTATCAATTATT
TCAAAAAACATTATCCAGAAAAATTGGCTGAACGCTTCAAACAAATGAAAATTGAAGAAGAAGCGCCTGTTATTATTATG
GACATGACCCGCGCCCTCGGTTTCCGAGATGACTATGACCGCTTTTACAGTCTCTTCGTGAAGGAAGTCCGTGATGGCAA
ACTCGGTAACTATACCTTAGATACATTGGAAGACCTCGATGGCAACGATTAA

Upstream 100 bases:

>100_bases
AGAACTGTTTGAACACCATTCATTTGAAAACTCTCTATGTTCAAACGATAGTAAAATAAAATAGGGTCTCTAAACCCTTG
CTACGAAAGGAAAAAACTCA

Downstream 100 bases:

>100_bases
AGAAATCAAAGAACTCCTTGTGACAGTCAAGGAGTTAGAAAGCCCTATTTTTTTAGAGCTTGAAAAGGATAATCGCTCAG
GAGTTCAAAAGGAAATCAGC

Product: ribosomal biogenesis GTPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 283; Mature: 282

Protein sequence:

>283_residues
MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPMLTKIVGDKPKLLILNKADLADPAMTKEWRQYFESQG
IQTLAINSKEQVTVKVVTDAAKKLMADKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKKHYPEKLAERFKQMKIEEEAPVIIM
DMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTLEDLDGND

Sequences:

>Translated_283_residues
MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPMLTKIVGDKPKLLILNKADLADPAMTKEWRQYFESQG
IQTLAINSKEQVTVKVVTDAAKKLMADKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKKHYPEKLAERFKQMKIEEEAPVIIM
DMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTLEDLDGND
>Mature_282_residues
ATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPMLTKIVGDKPKLLILNKADLADPAMTKEWRQYFESQGI
QTLAINSKEQVTVKVVTDAAKKLMADKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQW
LKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKKHYPEKLAERFKQMKIEEEAPVIIMD
MTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTLEDLDGND

Specific function: Binds GTP and GDP [H]

COG id: COG1161

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI93277113, Length=222, Percent_Identity=33.3333333333333, Blast_Score=131, Evalue=6e-31,
Organism=Homo sapiens, GI296317324, Length=244, Percent_Identity=25, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI9506611, Length=244, Percent_Identity=25, Blast_Score=75, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI193211047, Length=311, Percent_Identity=26.0450160771704, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17534827, Length=202, Percent_Identity=30.6930693069307, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI115535155, Length=177, Percent_Identity=31.0734463276836, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI25143545, Length=275, Percent_Identity=26.5454545454545, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI71982363, Length=177, Percent_Identity=31.0734463276836, Blast_Score=77, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6323744, Length=221, Percent_Identity=26.2443438914027, Blast_Score=67, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6320842, Length=189, Percent_Identity=28.042328042328, Blast_Score=64, Evalue=4e-11,
Organism=Drosophila melanogaster, GI85815858, Length=240, Percent_Identity=32.0833333333333, Blast_Score=115, Evalue=3e-26,
Organism=Drosophila melanogaster, GI28572990, Length=217, Percent_Identity=30.8755760368664, Blast_Score=79, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023179
- InterPro:   IPR019991
- InterPro:   IPR016478
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 32159; Mature: 32028

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPMLTKIVGDKPKLLILNK
CCEEEECCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCEEEEEC
ADLADPAMTKEWRQYFESQGIQTLAINSKEQVTVKVVTDAAKKLMADKIARQKERGIQIE
CCCCCHHHHHHHHHHHHHCCCEEEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHCCCHH
TLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQWLKTNKDLEILDTPGILWPK
EEHHHEEECCCCCHHHHHHHHCCCEEEEECCCCCCCCCHHHHHCCCCEEEEECCCCCCCC
FEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKKHYPEKLAERFKQMKIEEEAPVIIM
CCCCEEEEEEEEHHHHHHHCCCCCCEEEEEHHHHHHHCHHHHHHHHHHCCCCCCCCEEEE
DMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTLEDLDGND
ECHHHCCCCCHHHHHHHHHHHHHHCCCCCCEEHHHHHCCCCCC
>Mature Secondary Structure 
ATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPMLTKIVGDKPKLLILNK
CEEEECCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCEEEEEC
ADLADPAMTKEWRQYFESQGIQTLAINSKEQVTVKVVTDAAKKLMADKIARQKERGIQIE
CCCCCHHHHHHHHHHHHHCCCEEEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHCCCHH
TLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQWLKTNKDLEILDTPGILWPK
EEHHHEEECCCCCHHHHHHHHCCCEEEEECCCCCCCCCHHHHHCCCCEEEEECCCCCCCC
FEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKKHYPEKLAERFKQMKIEEEAPVIIM
CCCCEEEEEEEEHHHHHHHCCCCCCEEEEEHHHHHHHCHHHHHHHHHHCCCCCCCCEEEE
DMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTLEDLDGND
ECHHHCCCCCHHHHHHHHHHHHHHCCCCCCEEHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]