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The map label for this gene is yfmD [H]

Identifier: 169834298

GI number: 169834298

Start: 1044608

End: 1045615

Strand: Direct

Name: yfmD [H]

Synonym: SPH_1135

Alternate gene names: 169834298

Gene position: 1044608-1045615 (Clockwise)

Preceding gene: 169833231

Following gene: 169833839

Centisome position: 46.52

GC content: 33.23

Gene sequence:

>1008_bases
ATGCGAAATAAAAAACAAATAAACCTAGGCATAATTTTTGTAATCTGCCTAGGTCTTCTTATTACAATATTTTTGTCATT
AAAGCTTGGAACAAAAGAAATTAATATCAGAGATTTTTTAGCAGCTTTTGGAATGGGTAATACAAATGATGATTTTATTA
AATCAATTATATATAAAAGAATACCTAGAACTATTTTTGCAATTTTAGCAGGTTCTAGTCTTGCCATAAGCGGTGTATTG
ATGCAATCAGTTACTAGAAACCCAATAGCTGATCCAGGTATACTCGGTATAAACACAGGAGCAAGTCTTAGTGTAGTAAT
TGGTCTTTCTTTTTTAGGAATTTCATCAAGCATAAGCCATATAAGTTTTGCAATCATTGGTGGCTTAGTAAGTGCAATTT
TTGTATACGCGATTGCTGTAAGCGGAAAAGCAGGCCTTACCCCTATAAAACTTGCCTTATCAGGAACTTGTGTTAGTATG
GCTTTAAGCAGTTTTGTAAGTTTTTTAATTTTACCGAATAATAACGTCTTAGACAAATTTAGATTTTGGCAAATAGGTAG
CCTTGGAGCAGCTACATTATCTTCTATATCTACACTACTACCTTTTATAATTTTAGGTCACTTGATAGCTATATTTATTT
CATCAGATTTAAACGCTTTAGCTATGGGTGATGAAATGGCTGTTGGTCTTGGAGTTAATGTTAATAGGATAAGATCACTT
GCAATAATTGCAAGTGTGCTTTTATGTTCAAGTATTACTGCAATTGGTGGACCTATTGGCTTCGTAGGTCTTATAGTTCC
TCACTTTTGTGGCTTATTTATAAGCAAAGATATACGCACAATGACCATTTCTTCATCTTTTATAGGTGCAGAGCTCTTGC
TTATATGTGATATAATCGGCCGTATGTTAGGTAAACCAGGTGAAATTGAAGTAGGGATAATTACTGCAATAATCGGGGGT
CCAGTACTTATTTATGTAACTATGAAAAATAGAGGGGTTAATAACTAA

Upstream 100 bases:

>100_bases
CCAGATAATACACCGTTAGCAGCCTCATGCACTCCAACACCACTTTCAATAAACTATACTATTGAAGAATATCTAAATCT
TTTAGGAAATGCATGCAAAA

Downstream 100 bases:

>100_bases
TGCAAAATTTAATTATAGGTATTCAAAAAAGAAAAAATAGAATAACACTATTCTCCTCACTATTTTTATTAATAATAATC
AGTCTATCATTTTTCATTTT

Product: iron-compound ABC transporter, permease protein

Products: ADP; phosphate; ferric enterobactin [Cytoplasm] [C]

Alternate protein names: Ferric-citrate import system permease protein [H]

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MRNKKQINLGIIFVICLGLLITIFLSLKLGTKEINIRDFLAAFGMGNTNDDFIKSIIYKRIPRTIFAILAGSSLAISGVL
MQSVTRNPIADPGILGINTGASLSVVIGLSFLGISSSISHISFAIIGGLVSAIFVYAIAVSGKAGLTPIKLALSGTCVSM
ALSSFVSFLILPNNNVLDKFRFWQIGSLGAATLSSISTLLPFIILGHLIAIFISSDLNALAMGDEMAVGLGVNVNRIRSL
AIIASVLLCSSITAIGGPIGFVGLIVPHFCGLFISKDIRTMTISSSFIGAELLLICDIIGRMLGKPGEIEVGIITAIIGG
PVLIYVTMKNRGVNN

Sequences:

>Translated_335_residues
MRNKKQINLGIIFVICLGLLITIFLSLKLGTKEINIRDFLAAFGMGNTNDDFIKSIIYKRIPRTIFAILAGSSLAISGVL
MQSVTRNPIADPGILGINTGASLSVVIGLSFLGISSSISHISFAIIGGLVSAIFVYAIAVSGKAGLTPIKLALSGTCVSM
ALSSFVSFLILPNNNVLDKFRFWQIGSLGAATLSSISTLLPFIILGHLIAIFISSDLNALAMGDEMAVGLGVNVNRIRSL
AIIASVLLCSSITAIGGPIGFVGLIVPHFCGLFISKDIRTMTISSSFIGAELLLICDIIGRMLGKPGEIEVGIITAIIGG
PVLIYVTMKNRGVNN
>Mature_335_residues
MRNKKQINLGIIFVICLGLLITIFLSLKLGTKEINIRDFLAAFGMGNTNDDFIKSIIYKRIPRTIFAILAGSSLAISGVL
MQSVTRNPIADPGILGINTGASLSVVIGLSFLGISSSISHISFAIIGGLVSAIFVYAIAVSGKAGLTPIKLALSGTCVSM
ALSSFVSFLILPNNNVLDKFRFWQIGSLGAATLSSISTLLPFIILGHLIAIFISSDLNALAMGDEMAVGLGVNVNRIRSL
AIIASVLLCSSITAIGGPIGFVGLIVPHFCGLFISKDIRTMTISSSFIGAELLLICDIIGRMLGKPGEIEVGIITAIIGG
PVLIYVTMKNRGVNN

Specific function: Part of the ABC transporter complex yfmCDEF involved in citrate-dependent Fe(3+) import. Involved in the translocation of the substrate across the membrane (Probable) [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786805, Length=309, Percent_Identity=38.1877022653722, Blast_Score=183, Evalue=2e-47,
Organism=Escherichia coli, GI1790740, Length=325, Percent_Identity=31.3846153846154, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1790741, Length=279, Percent_Identity=31.8996415770609, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1786804, Length=305, Percent_Identity=31.1475409836066, Blast_Score=111, Evalue=7e-26,
Organism=Escherichia coli, GI1788004, Length=308, Percent_Identity=29.2207792207792, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1786347, Length=315, Percent_Identity=27.9365079365079, Blast_Score=98, Evalue=6e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 35171; Mature: 35171

Theoretical pI: Translated: 10.03; Mature: 10.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNKKQINLGIIFVICLGLLITIFLSLKLGTKEINIRDFLAAFGMGNTNDDFIKSIIYKR
CCCCCEECHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHH
IPRTIFAILAGSSLAISGVLMQSVTRNPIADPGILGINTGASLSVVIGLSFLGISSSISH
HHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCEEEECCCCCEEHHHHHHHHCCCHHHHH
ISFAIIGGLVSAIFVYAIAVSGKAGLTPIKLALSGTCVSMALSSFVSFLILPNNNVLDKF
HHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECHHHHHHHHHHHHHEEECCCCCCHHHH
RFWQIGSLGAATLSSISTLLPFIILGHLIAIFISSDLNALAMGDEMAVGLGVNVNRIRSL
HHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCEEEECCCCHHHHHHH
AIIASVLLCSSITAIGGPIGFVGLIVPHFCGLFISKDIRTMTISSSFIGAELLLICDIIG
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHH
RMLGKPGEIEVGIITAIIGGPVLIYVTMKNRGVNN
HHCCCCCCEEEEEEEEECCCCEEEEEEECCCCCCC
>Mature Secondary Structure
MRNKKQINLGIIFVICLGLLITIFLSLKLGTKEINIRDFLAAFGMGNTNDDFIKSIIYKR
CCCCCEECHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHH
IPRTIFAILAGSSLAISGVLMQSVTRNPIADPGILGINTGASLSVVIGLSFLGISSSISH
HHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCEEEECCCCCEEHHHHHHHHCCCHHHHH
ISFAIIGGLVSAIFVYAIAVSGKAGLTPIKLALSGTCVSMALSSFVSFLILPNNNVLDKF
HHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECHHHHHHHHHHHHHEEECCCCCCHHHH
RFWQIGSLGAATLSSISTLLPFIILGHLIAIFISSDLNALAMGDEMAVGLGVNVNRIRSL
HHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCEEEECCCCHHHHHHH
AIIASVLLCSSITAIGGPIGFVGLIVPHFCGLFISKDIRTMTISSSFIGAELLLICDIIG
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHH
RMLGKPGEIEVGIITAIIGGPVLIYVTMKNRGVNN
HHCCCCCCEEEEEEEEECCCCEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; ferric enterobactin [Periplasm]; H2O [C]

Specific reaction: ATP + ferric enterobactin [Periplasm] + H2O = ADP + phosphate + ferric enterobactin [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9272861; 9384377 [H]