Click here to switch to the map view.

The map label for this gene is xerS [H]

Identifier: 169834019

GI number: 169834019

Start: 1184794

End: 1185864

Strand: Direct

Name: xerS [H]

Synonym: SPH_1277

Alternate gene names: 169834019

Gene position: 1184794-1185864 (Clockwise)

Preceding gene: 169833048

Following gene: 169832947

Centisome position: 52.76

GC content: 39.31

Gene sequence:

>1071_bases
ATGAAACGTGAGATTTTACTGGAACGAATTGACAAACTAAAACAAATCATGCCCTGGTATGTTCTGGAATACTACCAATC
TAAGCTGGCTGTGCCCTACAGTTTTACAACCCTGTACGAATACCTCAAGGAATACGATCGATTTTTCAGCTGGGTTTTGG
AGTCTGGTATTTCAAACGCTGATAAAATGTCCGATATTCCTTTATCAGTTTTGGAAAATATGTCTAAGAAAGACATGGAA
TCCTTTATCCTTTATCTACGTGAACGTCCCTTGCTGAATGCTAATACAACCAAACAAGGTGTTTCACAGACAACTATCAA
TCGAACCTTATCAGCACTTTCTAGTCTTTACAAGTATCTAACCGAGGAGGTTGAAAACGATCAGGGGGAACCTTATTTCT
ATCGTAATGTAATGAAAAAAGTTTCAACAAAGAAAAAGAAAGAAACGCTTGCTGCTAGAGCTGAAAACATTAAGCAAAAA
CTCTTTCTAGGTGATGAAACTGAGGGTTTCCTAACTTATATCGACCAAGAGTATCCACAACAACTTTCAAATCGAGCTCT
TTCATCATTTAACAAAAATAAAGAACGAGATTTGGCCATTATTGCCCTTCTCTTGGCTTCTGGTGTCCGCTTATCTGAAG
CTGTTAATTTGGATCTAAGAGATCTCAATCTAAAAATGATGGTTATCGATGTCACTAGAAAAGGTGGCAAACGTGACTCT
GTCAATGTCGCCGCCTTTGCAAAACCTTATTTAGAAAATTATCTGGCCATTCGGAATCAACGCTATAAAACGGAAAAAAT
AGATACCGCTCTTTTTTTGACACTCTACAGAGGTGTTCCTAATCGTATCGATGCTTCTAGCGTTGAGAAAATGGTTGCTA
AGTATTCCGAGGACTTCAAAGTCCGTGTAACTCCCCATAAACTGCGCCATACGCTAGCAACCAGGCTCTATGATGCCACT
AAATCGCAAGTTTTGGTCAGTCACCAGCTAGGACATGCCAGCACACAAGTCACTGACCTCTATACCCATATCGTCAACGA
TGAACAAAAAAATGCCTTGGATAGCTTATAA

Upstream 100 bases:

>100_bases
TGAAAAACTCCTATAACATCTTTCTGAAAAACTATAATTTTCTTGAAAAATAAATAGGTCTATGCTATACTACTAGTAGA
CTTATTTAGGGAGAAAATAC

Downstream 100 bases:

>100_bases
ACTACATAAAATAAATTATGTAAAACGAAATTCAAAAAAAGAAGTTGCTAAAACTGTACTGCACCCCAAAAGTTAGACAG
AAAAAATCTAACTTTTGGGG

Product: site-specific tyrosine recombinase XerS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MKREILLERIDKLKQIMPWYVLEYYQSKLAVPYSFTTLYEYLKEYDRFFSWVLESGISNADKMSDIPLSVLENMSKKDME
SFILYLRERPLLNANTTKQGVSQTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
LFLGDETEGFLTYIDQEYPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLDLRDLNLKMMVIDVTRKGGKRDS
VNVAAFAKPYLENYLAIRNQRYKTEKIDTALFLTLYRGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDAT
KSQVLVSHQLGHASTQVTDLYTHIVNDEQKNALDSL

Sequences:

>Translated_356_residues
MKREILLERIDKLKQIMPWYVLEYYQSKLAVPYSFTTLYEYLKEYDRFFSWVLESGISNADKMSDIPLSVLENMSKKDME
SFILYLRERPLLNANTTKQGVSQTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
LFLGDETEGFLTYIDQEYPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLDLRDLNLKMMVIDVTRKGGKRDS
VNVAAFAKPYLENYLAIRNQRYKTEKIDTALFLTLYRGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDAT
KSQVLVSHQLGHASTQVTDLYTHIVNDEQKNALDSL
>Mature_356_residues
MKREILLERIDKLKQIMPWYVLEYYQSKLAVPYSFTTLYEYLKEYDRFFSWVLESGISNADKMSDIPLSVLENMSKKDME
SFILYLRERPLLNANTTKQGVSQTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
LFLGDETEGFLTYIDQEYPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLDLRDLNLKMMVIDVTRKGGKRDS
VNVAAFAKPYLENYLAIRNQRYKTEKIDTALFLTLYRGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDAT
KSQVLVSHQLGHASTQVTDLYTHIVNDEQKNALDSL

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division [H]

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerS subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790244, Length=251, Percent_Identity=28.6852589641434, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1789261, Length=315, Percent_Identity=23.1746031746032, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109
- InterPro:   IPR004107 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 41228; Mature: 41228

Theoretical pI: Translated: 9.61; Mature: 9.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKREILLERIDKLKQIMPWYVLEYYQSKLAVPYSFTTLYEYLKEYDRFFSWVLESGISNA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
DKMSDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVSQTTINRTLSALSSLYKYL
HHHCCCCHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
TEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQKLFLGDETEGFLTYIDQEYPQ
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
QLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLDLRDLNLKMMVIDVTRKGGKRDS
HHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHCCCEEECCEEEEEEEEECCCCCCCC
VNVAAFAKPYLENYLAIRNQRYKTEKIDTALFLTLYRGVPNRIDASSVEKMVAKYSEDFK
CCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCE
VRVTPHKLRHTLATRLYDATKSQVLVSHQLGHASTQVTDLYTHIVNDEQKNALDSL
EEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHCCC
>Mature Secondary Structure
MKREILLERIDKLKQIMPWYVLEYYQSKLAVPYSFTTLYEYLKEYDRFFSWVLESGISNA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
DKMSDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVSQTTINRTLSALSSLYKYL
HHHCCCCHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
TEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQKLFLGDETEGFLTYIDQEYPQ
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
QLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLDLRDLNLKMMVIDVTRKGGKRDS
HHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHCCCEEECCEEEEEEEEECCCCCCCC
VNVAAFAKPYLENYLAIRNQRYKTEKIDTALFLTLYRGVPNRIDASSVEKMVAKYSEDFK
CCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCE
VRVTPHKLRHTLATRLYDATKSQVLVSHQLGHASTQVTDLYTHIVNDEQKNALDSL
EEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA