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The map label for this gene is rpiA [H]

Identifier: 169834003

GI number: 169834003

Start: 856896

End: 857579

Strand: Direct

Name: rpiA [H]

Synonym: SPH_0926

Alternate gene names: 169834003

Gene position: 856896-857579 (Clockwise)

Preceding gene: 169832554

Following gene: 169834380

Centisome position: 38.16

GC content: 43.57

Gene sequence:

>684_bases
GTGGAAAATCTGAAGAAAATGGCAGGTATCAAGGCTGCTGAGTTCGTGAGCGATGGAATGGTCGTTGGACTGGGAACGGG
TTCTACTGCCTATTATTTTGTCGAAGAAATTGGTCGTCGTATCAAGGAAGAAGGATTGCAGATTACAGCTGTAACGACTT
CTAGTGTGACCAGTAAACAGGCTGAAGGGCTTAACATTCCACTCAAGTCTATTGACCAAGTAGACTTTGTCGATGTGACA
GTCGACGGAGCGGATGAAGTAGATAGTCAGTTTAATGGAATCAAAGGCGGTGGTGGTGCCCTTCTGATGGAGAAGATTGT
TGCAACGCCCTCAAAAGAATACATTTGGGTAGTGGATGAAAGCAAGCTGGTAGACAAACTAGGTGCTTTTAAATTGCCTG
TGGAAGTGGTTCAATATGGTGCAGAACAGATTTTTCGTCGTTTTGAGCGAGCTGGCTACAAACCAAGTTTCCGTGAAAAA
GATGGCCAACGTTTTGTGACCGATATGCAGAACTTTATCATTGACCTTGCCTTGGATGTCATCGAAGATCCAATTGTTTT
TGGACAAGAATTGGACCATGTCGTTGGTGTTGTAGAACACGGTTTATTCAACCAAATGGTGGACAAGGTCATTGTTGCTG
GACGAGATGGGGTTCAGATTTTAACCTCAAGAAAAGAAAAATAG

Upstream 100 bases:

>100_bases
TTTAAAGAAAGATTGATGAAAAATGTAGATTTGATGTTTTTACTTGAATAAAAAGCGGTTTCATAGTAAAATAAGAACTG
AGAATGATGGAGGTAAATCG

Downstream 100 bases:

>100_bases
AAGGGGGCATAAGATGTCTAAATTTAATCGTATTCACTTGGTGGTATTGGATTCTGTAGGAATTGGTGCTGCACCAGATG
CTAATAACTTTGTCAATGCA

Product: ribose-5-phosphate isomerase A

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI [H]

Number of amino acids: Translated: 227; Mature: 227

Protein sequence:

>227_residues
MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEEGLQITAVTTSSVTSKQAEGLNIPLKSIDQVDFVDVT
VDGADEVDSQFNGIKGGGGALLMEKIVATPSKEYIWVVDESKLVDKLGAFKLPVEVVQYGAEQIFRRFERAGYKPSFREK
DGQRFVTDMQNFIIDLALDVIEDPIVFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGVQILTSRKEK

Sequences:

>Translated_227_residues
MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEEGLQITAVTTSSVTSKQAEGLNIPLKSIDQVDFVDVT
VDGADEVDSQFNGIKGGGGALLMEKIVATPSKEYIWVVDESKLVDKLGAFKLPVEVVQYGAEQIFRRFERAGYKPSFREK
DGQRFVTDMQNFIIDLALDVIEDPIVFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGVQILTSRKEK
>Mature_227_residues
MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEEGLQITAVTTSSVTSKQAEGLNIPLKSIDQVDFVDVT
VDGADEVDSQFNGIKGGGGALLMEKIVATPSKEYIWVVDESKLVDKLGAFKLPVEVVQYGAEQIFRRFERAGYKPSFREK
DGQRFVTDMQNFIIDLALDVIEDPIVFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGVQILTSRKEK

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family [H]

Homologues:

Organism=Homo sapiens, GI94536842, Length=224, Percent_Identity=33.9285714285714, Blast_Score=103, Evalue=2e-22,
Organism=Escherichia coli, GI1789280, Length=222, Percent_Identity=37.3873873873874, Blast_Score=137, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI17551758, Length=238, Percent_Identity=36.5546218487395, Blast_Score=116, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6324669, Length=235, Percent_Identity=32.3404255319149, Blast_Score=93, Evalue=3e-20,
Organism=Drosophila melanogaster, GI281364072, Length=219, Percent_Identity=33.3333333333333, Blast_Score=88, Evalue=5e-18,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004788
- InterPro:   IPR020672 [H]

Pfam domain/function: PF06026 Rib_5-P_isom_A [H]

EC number: =5.3.1.6 [H]

Molecular weight: Translated: 24967; Mature: 24967

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEEGLQITAVTTSSVTSKQ
CCCHHHHHCCHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHH
AEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALLMEKIVATPSKEYIWVVDE
CCCCCCCHHHCCCCEEEEEEECCHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCEEEEECC
SKLVDKLGAFKLPVEVVQYGAEQIFRRFERAGYKPSFREKDGQRFVTDMQNFIIDLALDV
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
IEDPIVFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGVQILTSRKEK
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCC
>Mature Secondary Structure
MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEEGLQITAVTTSSVTSKQ
CCCHHHHHCCHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHH
AEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALLMEKIVATPSKEYIWVVDE
CCCCCCCHHHCCCCEEEEEEECCHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCEEEEECC
SKLVDKLGAFKLPVEVVQYGAEQIFRRFERAGYKPSFREKDGQRFVTDMQNFIIDLALDV
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
IEDPIVFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGVQILTSRKEK
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA