Click here to switch to the map view.

The map label for this gene is murA1 [H]

Identifier: 169833968

GI number: 169833968

Start: 1077173

End: 1078432

Strand: Direct

Name: murA1 [H]

Synonym: SPH_1173

Alternate gene names: 169833968

Gene position: 1077173-1078432 (Clockwise)

Preceding gene: 169832700

Following gene: 169832611

Centisome position: 47.97

GC content: 40.79

Gene sequence:

>1260_bases
ATGAGAAAAATTGTTATCAATGGTGGATTACCACTGCAAGGTGAAATCACTATTAGTGGTGCTAAAAATAGTGTCGTTGC
CTTAATTCCAGCTATTATCTTGGCTGATGATGTGGTGACTTTGGATTGCGTTCCAGATATTTCGGATGTAGCCAGTCTTG
TCGAAATCATGGAATTGATGGGAGCTACTGTTAAGCGTTATGACGATGTATTGGAGATTGACCCAAGAGGTGTTCAAAAT
ATTCCAATGCCTTATGGTAAAATTAACAGTCTTCGTGCATCTTACTATTTTTATGGGAGCCTCTTAGGCCGTTTTGGTGA
AGCGACAGTTGGTCTACCGGGAGGATGTGATCTTGGTCCTCGTCCGATTGACTTACACCTTAAGGCGTTTGAAGCTATGG
GTGCCACTGCTAGCTACGAGGGAGATAACATGAAGTTATCTGCTAAAGATACAGGACTTCATGGTGCAAGTATTTACATG
GATACGGTTAGTGTGGGAGCAACGATTAATACGATGATTGCTGCGGTTAAAGCAAATGGTCGTACTATTATTGAAAATGC
AGCCCGTGAACCTGAGATTATTGATGTAGCTACTCTCTTGAATAATATGGGTGCCCATATCCGTGGGGCAGGAACTAATA
TCATCATTATTGATGGTGTTGAAAGATTACATGGGACACGTCATCAGGTGATTCCAGACCGCATTGAAGCTGGAACATAT
ATATCTTTAGCTGCTGCAGTTGGTAAAGGAATTCGTATAAATAATGTTCTTTACGAACACCTGGAAGGGTTTATTGCTAA
GTTGGAAGAAATGGGAGTGAGAATGACTGTATCTGAGGACAGCATTTTTGTCGAGGAACAGTCTAATTTGAAAGCAATCA
ATATTAAGACAGCTCCTTACCCAGGCTTTGCAACTGATTTGCAACAACCGCTTACCCCTCTTTTACTAAGAGCGAATGGT
CGTGGTACAATTGTCGATACGATTTACGAAAAACGTGTAAATCATGTTTTTGAACTAGCAAAGATGGATGCGGATATTTC
GACAACAAATGGTCATATTTTGTACACGGGTGGACGTGATTTACGTGGGACCAGTGTTAAAGCGACCGACTTAAGAGCTG
GGGCTGCACTAGTCATTGCTGGGCTTATGGCTGAAGGTAAAACTGAAATTACCAATATCGAGTTTATCTTACGTGGTTAT
TCTGATATTATCGAAAAATTACGTAATTTAGGAGCGGATATTAGACTTGTTGAGGATTAA

Upstream 100 bases:

>100_bases
ATCCAATAAAATTGAAAAGGATGGAAAAAAGGATAAATTTATGATATACTTTATTTTGAAGACCTTATTAGAAATCTTGA
AAGAGTATTGAAAACTTAGA

Downstream 100 bases:

>100_bases
ACCGTAGAGGTGTTTATGAATATTTGGACCAAATTAGCAATGTTTTCTTTTTTTGAAACGGATCGCTTGTATTTGCGTCC
TTTCTTTTTTAGTGATAGTC

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase 2; UDP-N-acetylglucosamine enolpyruvyl transferase 2; EPT 2 [H]

Number of amino acids: Translated: 419; Mature: 419

Protein sequence:

>419_residues
MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCVPDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQN
IPMPYGKINSLRASYYFYGSLLGRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYM
DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIIDGVERLHGTRHQVIPDRIEAGTY
ISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMTVSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANG
RGTIVDTIYEKRVNHVFELAKMDADISTTNGHILYTGGRDLRGTSVKATDLRAGAALVIAGLMAEGKTEITNIEFILRGY
SDIIEKLRNLGADIRLVED

Sequences:

>Translated_419_residues
MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCVPDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQN
IPMPYGKINSLRASYYFYGSLLGRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYM
DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIIDGVERLHGTRHQVIPDRIEAGTY
ISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMTVSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANG
RGTIVDTIYEKRVNHVFELAKMDADISTTNGHILYTGGRDLRGTSVKATDLRAGAALVIAGLMAEGKTEITNIEFILRGY
SDIIEKLRNLGADIRLVED
>Mature_419_residues
MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCVPDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQN
IPMPYGKINSLRASYYFYGSLLGRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYM
DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIIDGVERLHGTRHQVIPDRIEAGTY
ISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMTVSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANG
RGTIVDTIYEKRVNHVFELAKMDADISTTNGHILYTGGRDLRGTSVKATDLRAGAALVIAGLMAEGKTEITNIEFILRGY
SDIIEKLRNLGADIRLVED

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=420, Percent_Identity=45.2380952380952, Blast_Score=331, Evalue=5e-92,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 45056; Mature: 45056

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCVPDISDVASLVEIMELM
CCEEEEECCCCEEEEEEEECCCCCHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHH
GATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLLGRFGEATVGLPGGCDLGP
HHHHHHCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCC
RPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYMDTVSVGATINTMIAAVKANG
CCEEEEEEEHHHCCCCEEECCCCEEEEECCCCCCCCEEEEEEEECCCCHHHEEEEEECCC
RTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIIDGVERLHGTRHQVIPDRIEAGTY
CEEEHHCCCCCCEEHHHHHHHHCCCEEEECCCEEEEECCHHHHCCCCCCCCCHHHCCCCE
ISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMTVSEDSIFVEEQSNLKAINIKTAPY
EEEHHHHCCCCEEHHHHHHHHHHHHHHHHHCCEEEEECCCEEEEEECCCEEEEEEECCCC
PGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVNHVFELAKMDADISTTNGHILYTGGRD
CCCHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCC
LRGTSVKATDLRAGAALVIAGLMAEGKTEITNIEFILRGYSDIIEKLRNLGADIRLVED
CCCCCEEECCCCCCHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHCCCCEEEECC
>Mature Secondary Structure
MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCVPDISDVASLVEIMELM
CCEEEEECCCCEEEEEEEECCCCCHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHH
GATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLLGRFGEATVGLPGGCDLGP
HHHHHHCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCC
RPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYMDTVSVGATINTMIAAVKANG
CCEEEEEEEHHHCCCCEEECCCCEEEEECCCCCCCCEEEEEEEECCCCHHHEEEEEECCC
RTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIIDGVERLHGTRHQVIPDRIEAGTY
CEEEHHCCCCCCEEHHHHHHHHCCCEEEECCCEEEEECCHHHHCCCCCCCCCHHHCCCCE
ISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMTVSEDSIFVEEQSNLKAINIKTAPY
EEEHHHHCCCCEEHHHHHHHHHHHHHHHHHCCEEEEECCCEEEEEECCCEEEEEEECCCC
PGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVNHVFELAKMDADISTTNGHILYTGGRD
CCCHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCC
LRGTSVKATDLRAGAALVIAGLMAEGKTEITNIEFILRGYSDIIEKLRNLGADIRLVED
CCCCCEEECCCCCCHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11463916 [H]