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The map label for this gene is srlR [H]

Identifier: 169833948

GI number: 169833948

Start: 2169934

End: 2170707

Strand: Direct

Name: srlR [H]

Synonym: SPH_2362

Alternate gene names: 169833948

Gene position: 2169934-2170707 (Clockwise)

Preceding gene: 169833173

Following gene: 169834232

Centisome position: 96.63

GC content: 34.11

Gene sequence:

>774_bases
ATGATAAAAGATGAACGTGTACTTGAATTGATTGAAATTATTAAAAAGAAAAAAAGAATTGCCGTAAAAGAGCTGGCAGA
AATCACTTTCTCCAGCACAAGTACCTTACGTCGTGATTTAATTTTCTTAGAAAATCAAGGTCTTATCAAAAGAAAGCACG
GATACGTGACCCTGTCCTCTATGAACACAATTGAACTTTCTCATCAAATACGGGAAGGAGAAAGTACTAGGCAAAAAAGA
CTAATCGCTAGTCTCGCTAAAGACTTTATTCGGTCAGGTATGTGTGTTTATCTGGATTCCAGTACGACTGTCTACGAACT
TTGTCCCTATCTTTCTGAACTTGATAATTTGATTATTTTTACAAATGGTTTACATACTGCACAAACCCTATCTGAAACTG
TTAAAGATAGCTCCAAAATCTTTATCACATCTGGCGAGGTCAAACATCAATCCTGTTCCGTGGTCAATTACGATAAGGAA
AATTCTTTATTAGATCATTTTAATATCGATTTAGCATTTTGTTCAGCAAGAGGTATTGATGACCAATATGTTTATGAAGC
TTCTCTCAGCCAAGCTATTTCAAAAAAGAATATTATTGACAAAGCCCATGAAACCATCTTACTGATTGATAGCTCTAAAT
TTTACAAGACTGGATTTTTTAAAATTAATCCCCTCTCCAAATACACAACCTTTATTTCTGACACCTTGCCAAATCAAAAA
TTATTAGACGCAGTCGAATTATTTGATGGAGAATGGGTTTCTGATATTCAATGA

Upstream 100 bases:

>100_bases
TTGGATAATGTTCAAATGTTAACCCAATATTCATAAAAATAATTCAAATTCCTCCAATTTGTGCTATAATATAGTTGAAA
TGATAAATTAGGAGGAGCTT

Downstream 100 bases:

>100_bases
AAATCAAATAGGAAGCTAGTCTCAGCTTGCTCAAAGTACAGATTTGAAAACTGATGAAGTCAAGTCCCCCATGGACACGG
CAAGACGAAGCTGACATGAT

Product: regulator of fucose operon

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MIKDERVLELIEIIKKKKRIAVKELAEITFSSTSTLRRDLIFLENQGLIKRKHGYVTLSSMNTIELSHQIREGESTRQKR
LIASLAKDFIRSGMCVYLDSSTTVYELCPYLSELDNLIIFTNGLHTAQTLSETVKDSSKIFITSGEVKHQSCSVVNYDKE
NSLLDHFNIDLAFCSARGIDDQYVYEASLSQAISKKNIIDKAHETILLIDSSKFYKTGFFKINPLSKYTTFISDTLPNQK
LLDAVELFDGEWVSDIQ

Sequences:

>Translated_257_residues
MIKDERVLELIEIIKKKKRIAVKELAEITFSSTSTLRRDLIFLENQGLIKRKHGYVTLSSMNTIELSHQIREGESTRQKR
LIASLAKDFIRSGMCVYLDSSTTVYELCPYLSELDNLIIFTNGLHTAQTLSETVKDSSKIFITSGEVKHQSCSVVNYDKE
NSLLDHFNIDLAFCSARGIDDQYVYEASLSQAISKKNIIDKAHETILLIDSSKFYKTGFFKINPLSKYTTFISDTLPNQK
LLDAVELFDGEWVSDIQ
>Mature_257_residues
MIKDERVLELIEIIKKKKRIAVKELAEITFSSTSTLRRDLIFLENQGLIKRKHGYVTLSSMNTIELSHQIREGESTRQKR
LIASLAKDFIRSGMCVYLDSSTTVYELCPYLSELDNLIIFTNGLHTAQTLSETVKDSSKIFITSGEVKHQSCSVVNYDKE
NSLLDHFNIDLAFCSARGIDDQYVYEASLSQAISKKNIIDKAHETILLIDSSKFYKTGFFKINPLSKYTTFISDTLPNQK
LLDAVELFDGEWVSDIQ

Specific function: Unknown

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789059, Length=218, Percent_Identity=31.651376146789, Blast_Score=100, Evalue=9e-23,
Organism=Escherichia coli, GI1789519, Length=233, Percent_Identity=28.755364806867, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI226510968, Length=238, Percent_Identity=28.1512605042017, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1789829, Length=238, Percent_Identity=27.7310924369748, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1788069, Length=257, Percent_Identity=26.8482490272374, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI87082344, Length=234, Percent_Identity=25.6410256410256, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1789170, Length=237, Percent_Identity=28.6919831223629, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1787063, Length=244, Percent_Identity=25.8196721311475, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1790753, Length=240, Percent_Identity=25.8333333333333, Blast_Score=67, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 29283; Mature: 29283

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKDERVLELIEIIKKKKRIAVKELAEITFSSTSTLRRDLIFLENQGLIKRKHGYVTLSS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHEEEECCCCCEEECCCEEEECC
MNTIELSHQIREGESTRQKRLIASLAKDFIRSGMCVYLDSSTTVYELCPYLSELDNLIIF
CCEEHHHHHHHCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHCCCEEEE
TNGLHTAQTLSETVKDSSKIFITSGEVKHQSCSVVNYDKENSLLDHFNIDLAFCSARGID
ECCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEEECCCCCHHHHCCCEEEEEECCCCC
DQYVYEASLSQAISKKNIIDKAHETILLIDSSKFYKTGFFKINPLSKYTTFISDTLPNQK
HHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCEEECCEEECCHHHHHHHHHHCCCCHH
LLDAVELFDGEWVSDIQ
HHHHHHHHCCCHHCCCC
>Mature Secondary Structure
MIKDERVLELIEIIKKKKRIAVKELAEITFSSTSTLRRDLIFLENQGLIKRKHGYVTLSS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHEEEECCCCCEEECCCEEEECC
MNTIELSHQIREGESTRQKRLIASLAKDFIRSGMCVYLDSSTTVYELCPYLSELDNLIIF
CCEEHHHHHHHCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHCCCEEEE
TNGLHTAQTLSETVKDSSKIFITSGEVKHQSCSVVNYDKENSLLDHFNIDLAFCSARGID
ECCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEEECCCCCHHHHCCCEEEEEECCCCC
DQYVYEASLSQAISKKNIIDKAHETILLIDSSKFYKTGFFKINPLSKYTTFISDTLPNQK
HHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCEEECCEEECCHHHHHHHHHHCCCCHH
LLDAVELFDGEWVSDIQ
HHHHHHHHCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3062173; 9278503; 9205837 [H]