Click here to switch to the map view.

The map label for this gene is yheS [H]

Identifier: 169833687

GI number: 169833687

Start: 1298046

End: 1299605

Strand: Direct

Name: yheS [H]

Synonym: SPH_1398

Alternate gene names: 169833687

Gene position: 1298046-1299605 (Clockwise)

Preceding gene: 169832948

Following gene: 169834139

Centisome position: 57.8

GC content: 39.62

Gene sequence:

>1560_bases
ATGCACTATGAACATTCTAGAAAGGGAAATCATATGATAAAAATCAATCATCTAACCATCACACAAAACAAAGATTTACG
AGATCTTGTATCTGACCTAAGCATGACCATCCAAGACGGGGAAAAGGTTGCTATTATTGGTGAAGAAGGAAATGGCAAAT
CAACCTTACTTAAAATTTTAATGGGGGAAGCTTTGTCTGATTTCACTATCAAGGGAAACATCCAATCTGACTATCAGTCA
CTGGCCTACATTCCTCAAAAACTTCCCGAGGAGCTGAAAAAGAAAACTTTACACGACTACTTCTTTTTAGATTCTATTGA
TTTAGACTACAGTATCCTCTATCGTTTGGCGGAGGAATTGCATTTTGATAGCAATCGTTTCGCAAGTGACCAAAAGATTG
GCAATCTATCAGGGGGAGAAGCTTTGAAAATTCAGCTTATCCATGAGTTAGCCAAACCCTTTGAGATTCTATTTTTAGAT
GAACCTTCAAATGACCTAGACCTTGAGACAGTTGATTGGCTAAAAGGCCAGATTCAAAAGACCAGGCAAACCGTTATTTT
CATTTCCCATGATGAAGACTTTCTTTCTGAAACAGCAGACACTATTGTTCACTTGCGACTGGTCAAACACCGTAAAGAAG
CGGAAACGCTAGTAGAGCATTTAGACTATGATAGCTATAGTGAGCAGAGAAAGGCTAATTTTGCCAAACAAAGTCAGCAA
GCTGCTAACAACCAAAGAGCCTACGATAAAACCATGGAAAAACATCGGAGAGTTAAGCAAAATGTAGAAACTGCGCTTCG
AGCTACCAAAGATAGTACTGCCGGTCGCCTATTGGCTAAAAAGATGAAAACTGTCCTCTCACAAGAAAAACGCTACGAAA
AGACAGCTCAGTCCATGACTCAAAAGCCACTTGAAGAGGAACAAATCCAACTTTTCTTTTCAGACATCCAACCATTACCA
GCTTCTAAAGTCTTAGTCCAACTGGAAAAAGAAAATTTGTCCATTGACGACCGAGTTTTGGTTCAAAAACTACAACTAAC
TGTCCGTGGGCAAGAAAAAATCGGTATTATCGGGCCAAATGGTGTTGGGAAATCAACTCTGTTAGCCAAATTAAAGCAAC
TTCTGAATGATAAAAGAGAGATTTCCCTTGGTTTTATGCCACAAGATTACCACAAAAAACTGCAATTGGATTTATCACCA
ATAGCTTATATCAGCAAAACTGGGGAAAAAGAGGAACTTCAGAAAATCCAATCTCACCTAGCCAGTCTCAATTTCAGTTA
TCCAGAAATGCAGCATCAAATTCGCTCCTTATCTGGCGGACAACAGGGAAAACTCCTGCTTTTGGATTTAGTCCTGCGCA
AACCAAACTTTCTCCTGCTGGATGAACCCACACGAAACTTTTCTCCCACTTCTCAACCCCAAATCAGAAAACTCTTTGCA
ACCTATCCAGGCGGTCTCATCACTGTTTCGCATGACCGTCGTTTCTTAAAAGAAATCTGCTCGATCATCTATCGCATGAC
AGAACACGGTTTGAAGCTAGTTAATTTAGAAGATTTATAA

Upstream 100 bases:

>100_bases
TCTCTTTTTGTGTGCTCTTTTATGCTCTTTTTCTGGCATGTTAATAGAGTTTTTTTGACATAGACTTTGGGCTCTACTAG
GTAAAGTAGAGCTTTTTGTT

Downstream 100 bases:

>100_bases
ATTTGCAACATAGCAGATAGGTGGGGCAAAAACACAATTTTAGGAGAAAAAGAAGTAAATCTTCCCATAGTAAAACGCAT
AATATCAAGTTTTCACACCT

Product: ABC transporter, ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 519; Mature: 519

Protein sequence:

>519_residues
MHYEHSRKGNHMIKINHLTITQNKDLRDLVSDLSMTIQDGEKVAIIGEEGNGKSTLLKILMGEALSDFTIKGNIQSDYQS
LAYIPQKLPEELKKKTLHDYFFLDSIDLDYSILYRLAEELHFDSNRFASDQKIGNLSGGEALKIQLIHELAKPFEILFLD
EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLVEHLDYDSYSEQRKANFAKQSQQ
AANNQRAYDKTMEKHRRVKQNVETALRATKDSTAGRLLAKKMKTVLSQEKRYEKTAQSMTQKPLEEEQIQLFFSDIQPLP
ASKVLVQLEKENLSIDDRVLVQKLQLTVRGQEKIGIIGPNGVGKSTLLAKLKQLLNDKREISLGFMPQDYHKKLQLDLSP
IAYISKTGEKEELQKIQSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDLVLRKPNFLLLDEPTRNFSPTSQPQIRKLFA
TYPGGLITVSHDRRFLKEICSIIYRMTEHGLKLVNLEDL

Sequences:

>Translated_519_residues
MHYEHSRKGNHMIKINHLTITQNKDLRDLVSDLSMTIQDGEKVAIIGEEGNGKSTLLKILMGEALSDFTIKGNIQSDYQS
LAYIPQKLPEELKKKTLHDYFFLDSIDLDYSILYRLAEELHFDSNRFASDQKIGNLSGGEALKIQLIHELAKPFEILFLD
EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLVEHLDYDSYSEQRKANFAKQSQQ
AANNQRAYDKTMEKHRRVKQNVETALRATKDSTAGRLLAKKMKTVLSQEKRYEKTAQSMTQKPLEEEQIQLFFSDIQPLP
ASKVLVQLEKENLSIDDRVLVQKLQLTVRGQEKIGIIGPNGVGKSTLLAKLKQLLNDKREISLGFMPQDYHKKLQLDLSP
IAYISKTGEKEELQKIQSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDLVLRKPNFLLLDEPTRNFSPTSQPQIRKLFA
TYPGGLITVSHDRRFLKEICSIIYRMTEHGLKLVNLEDL
>Mature_519_residues
MHYEHSRKGNHMIKINHLTITQNKDLRDLVSDLSMTIQDGEKVAIIGEEGNGKSTLLKILMGEALSDFTIKGNIQSDYQS
LAYIPQKLPEELKKKTLHDYFFLDSIDLDYSILYRLAEELHFDSNRFASDQKIGNLSGGEALKIQLIHELAKPFEILFLD
EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLVEHLDYDSYSEQRKANFAKQSQQ
AANNQRAYDKTMEKHRRVKQNVETALRATKDSTAGRLLAKKMKTVLSQEKRYEKTAQSMTQKPLEEEQIQLFFSDIQPLP
ASKVLVQLEKENLSIDDRVLVQKLQLTVRGQEKIGIIGPNGVGKSTLLAKLKQLLNDKREISLGFMPQDYHKKLQLDLSP
IAYISKTGEKEELQKIQSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDLVLRKPNFLLLDEPTRNFSPTSQPQIRKLFA
TYPGGLITVSHDRRFLKEICSIIYRMTEHGLKLVNLEDL

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI27881506, Length=514, Percent_Identity=24.5136186770428, Blast_Score=135, Evalue=7e-32,
Organism=Homo sapiens, GI10947137, Length=514, Percent_Identity=24.5136186770428, Blast_Score=135, Evalue=8e-32,
Organism=Homo sapiens, GI148612853, Length=397, Percent_Identity=25.1889168765743, Blast_Score=133, Evalue=5e-31,
Organism=Homo sapiens, GI69354671, Length=391, Percent_Identity=27.1099744245524, Blast_Score=115, Evalue=7e-26,
Organism=Homo sapiens, GI10947135, Length=391, Percent_Identity=27.1099744245524, Blast_Score=115, Evalue=9e-26,
Organism=Escherichia coli, GI1789751, Length=537, Percent_Identity=28.4916201117318, Blast_Score=194, Evalue=1e-50,
Organism=Escherichia coli, GI2367384, Length=539, Percent_Identity=29.3135435992579, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1787041, Length=540, Percent_Identity=25.7407407407407, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI1787182, Length=521, Percent_Identity=26.8714011516315, Blast_Score=139, Evalue=5e-34,
Organism=Escherichia coli, GI87081791, Length=226, Percent_Identity=27.8761061946903, Blast_Score=62, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17555318, Length=541, Percent_Identity=25.3234750462107, Blast_Score=152, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI17553372, Length=532, Percent_Identity=25.3759398496241, Blast_Score=139, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI17559834, Length=536, Percent_Identity=25.1865671641791, Blast_Score=130, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6321121, Length=550, Percent_Identity=24.5454545454545, Blast_Score=136, Evalue=9e-33,
Organism=Saccharomyces cerevisiae, GI6320874, Length=518, Percent_Identity=25.4826254826255, Blast_Score=132, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6323278, Length=193, Percent_Identity=31.6062176165803, Blast_Score=80, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6324314, Length=193, Percent_Identity=31.6062176165803, Blast_Score=78, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6325030, Length=182, Percent_Identity=30.2197802197802, Blast_Score=77, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24642252, Length=532, Percent_Identity=25.3759398496241, Blast_Score=142, Evalue=4e-34,
Organism=Drosophila melanogaster, GI18859989, Length=532, Percent_Identity=25.3759398496241, Blast_Score=142, Evalue=4e-34,
Organism=Drosophila melanogaster, GI24666836, Length=530, Percent_Identity=24.7169811320755, Blast_Score=142, Evalue=5e-34,
Organism=Drosophila melanogaster, GI24641342, Length=538, Percent_Identity=26.7657992565056, Blast_Score=124, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 59547; Mature: 59547

Theoretical pI: Translated: 7.95; Mature: 7.95

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHYEHSRKGNHMIKINHLTITQNKDLRDLVSDLSMTIQDGEKVAIIGEEGNGKSTLLKIL
CCCCCCCCCCEEEEEEEEEEECCCCHHHHHHHHHHEECCCCEEEEEECCCCCHHHHHHHH
MGEALSDFTIKGNIQSDYQSLAYIPQKLPEELKKKTLHDYFFLDSIDLDYSILYRLAEEL
HHHHHCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHH
HFDSNRFASDQKIGNLSGGEALKIQLIHELAKPFEILFLDEPSNDLDLETVDWLKGQIQK
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHH
TRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLVEHLDYDSYSEQRKANFAKQSQQ
CCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
AANNQRAYDKTMEKHRRVKQNVETALRATKDSTAGRLLAKKMKTVLSQEKRYEKTAQSMT
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLSIDDRVLVQKLQLTVRGQEKIGIIGPN
HCCCHHHHHHHHHHHCCCCCHHHHHEEECCCCCCCHHHHHHHHHHHHEECCCEEEEECCC
GVGKSTLLAKLKQLLNDKREISLGFMPQDYHKKLQLDLSPIAYISKTGEKEELQKIQSHL
CCCHHHHHHHHHHHHCCCCEEEECCCCHHHHHHEECCCCHHHHHHCCCCHHHHHHHHHHH
ASLNFSYPEMQHQIRSLSGGQQGKLLLLDLVLRKPNFLLLDEPTRNFSPTSQPQIRKLFA
HHCCCCCHHHHHHHHHHCCCCCCCEEHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHH
TYPGGLITVSHDRRFLKEICSIIYRMTEHGLKLVNLEDL
HCCCCEEEECCCHHHHHHHHHHHHHHHHCCEEEEEECCC
>Mature Secondary Structure
MHYEHSRKGNHMIKINHLTITQNKDLRDLVSDLSMTIQDGEKVAIIGEEGNGKSTLLKIL
CCCCCCCCCCEEEEEEEEEEECCCCHHHHHHHHHHEECCCCEEEEEECCCCCHHHHHHHH
MGEALSDFTIKGNIQSDYQSLAYIPQKLPEELKKKTLHDYFFLDSIDLDYSILYRLAEEL
HHHHHCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHH
HFDSNRFASDQKIGNLSGGEALKIQLIHELAKPFEILFLDEPSNDLDLETVDWLKGQIQK
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHH
TRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLVEHLDYDSYSEQRKANFAKQSQQ
CCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
AANNQRAYDKTMEKHRRVKQNVETALRATKDSTAGRLLAKKMKTVLSQEKRYEKTAQSMT
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLSIDDRVLVQKLQLTVRGQEKIGIIGPN
HCCCHHHHHHHHHHHCCCCCHHHHHEEECCCCCCCHHHHHHHHHHHHEECCCEEEEECCC
GVGKSTLLAKLKQLLNDKREISLGFMPQDYHKKLQLDLSPIAYISKTGEKEELQKIQSHL
CCCHHHHHHHHHHHHCCCCEEEECCCCHHHHHHEECCCCHHHHHHCCCCHHHHHHHHHHH
ASLNFSYPEMQHQIRSLSGGQQGKLLLLDLVLRKPNFLLLDEPTRNFSPTSQPQIRKLFA
HHCCCCCHHHHHHHHHHCCCCCCCEEHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHH
TYPGGLITVSHDRRFLKEICSIIYRMTEHGLKLVNLEDL
HCCCCEEEECCCHHHHHHHHHHHHHHHHCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]