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The map label for this gene is tadA [H]

Identifier: 169833520

GI number: 169833520

Start: 58253

End: 58720

Strand: Direct

Name: tadA [H]

Synonym: SPH_0069

Alternate gene names: 169833520

Gene position: 58253-58720 (Clockwise)

Preceding gene: 169832565

Following gene: 169832832

Centisome position: 2.59

GC content: 44.02

Gene sequence:

>468_bases
ATGTATTATACGCTTGAAGAAAAAGAAGTCTTTATGAGGGAGGCTTTGAGAGAGGCTGAGATTGCTCTTGAACACGATGA
AATTCCAATTGGTTGTGTGATTGTCAAAGATGGGGAAATCATTGGTCGTGGGCATAATGCGCGTGAGGAATTACAGCGAG
CGGTTATGCATGCGGAAATTATGGCTATAGAGGATGCGAACTTGAGTGAGGAGAGCTGGCGCTTGCTGGATTGCACACTT
TTTGTGACCATTGAACCTTGTGTCATGTGTAGTGGGGCGATTGGGCTTGCCCGCATTCCAAATGTGGTCTATGGGGCTAA
AAACCAGAAATTTGGCGCTGCTGGGAGTTTGTACGATATCTTGACAGATGAGCGTCTCAATCATCGTGTGGAGGTTGAAA
TAGGAATTTTGGAAGATGAATGCGCAGCTATCATGCAGGATTTTTTTAGAAATAGACGGAAAAAATAA

Upstream 100 bases:

>100_bases
CATAATAATCTCCCTATAGAGTCACCGCATTCGGTGGCTTCTTTTGTGTTGGGATTCATGATATAATAATAAAATCGATA
AGTAGGAAAAGAGAAAAGAG

Downstream 100 bases:

>100_bases
TTTTGCTTTTAAAATGAATAGGAATGTGATATAATAAATAGTGGAGCAACAGTTCTGCGTGAAGCGGGTCAGGGGAGGAA
TCCAGCAGCCCTAAGCGATT

Product: tRNA-specific adenosine deaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 155; Mature: 155

Protein sequence:

>155_residues
MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRGHNAREELQRAVMHAEIMAIEDANLSEESWRLLDCTL
FVTIEPCVMCSGAIGLARIPNVVYGAKNQKFGAAGSLYDILTDERLNHRVEVEIGILEDECAAIMQDFFRNRRKK

Sequences:

>Translated_155_residues
MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRGHNAREELQRAVMHAEIMAIEDANLSEESWRLLDCTL
FVTIEPCVMCSGAIGLARIPNVVYGAKNQKFGAAGSLYDILTDERLNHRVEVEIGILEDECAAIMQDFFRNRRKK
>Mature_155_residues
MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRGHNAREELQRAVMHAEIMAIEDANLSEESWRLLDCTL
FVTIEPCVMCSGAIGLARIPNVVYGAKNQKFGAAGSLYDILTDERLNHRVEVEIGILEDECAAIMQDFFRNRRKK

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=155, Percent_Identity=33.5483870967742, Blast_Score=101, Evalue=3e-22,
Organism=Escherichia coli, GI145693172, Length=147, Percent_Identity=48.9795918367347, Blast_Score=147, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI17541138, Length=152, Percent_Identity=34.2105263157895, Blast_Score=91, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17554608, Length=100, Percent_Identity=39, Blast_Score=77, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6322425, Length=118, Percent_Identity=36.4406779661017, Blast_Score=82, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6325319, Length=142, Percent_Identity=35.2112676056338, Blast_Score=75, Evalue=4e-15,
Organism=Drosophila melanogaster, GI21355527, Length=148, Percent_Identity=35.1351351351351, Blast_Score=90, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 17630; Mature: 17630

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRGHNAREELQRAVMHAEI
CEEECCHHHHHHHHHHHHHHHEEECCCCCEEEEEEECCEEEECCCCHHHHHHHHHHHHHH
MAIEDANLSEESWRLLDCTLFVTIEPCVMCSGAIGLARIPNVVYGAKNQKFGAAGSLYDI
EEEECCCCCCCCEEEEEEEEEEEECHHHHCCCCCCHHHCCHHEECCCCCCCCCCCCHHHH
LTDERLNHRVEVEIGILEDECAAIMQDFFRNRRKK
HCCCCCCCEEEEEEEEECHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRGHNAREELQRAVMHAEI
CEEECCHHHHHHHHHHHHHHHEEECCCCCEEEEEEECCEEEECCCCHHHHHHHHHHHHHH
MAIEDANLSEESWRLLDCTLFVTIEPCVMCSGAIGLARIPNVVYGAKNQKFGAAGSLYDI
EEEECCCCCCCCEEEEEEEEEEEECHHHHCCCCCCHHHCCHHEECCCCCCCCCCCCHHHH
LTDERLNHRVEVEIGILEDECAAIMQDFFRNRRKK
HCCCCCCCEEEEEEEEECHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]