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The map label for this gene is cisA [H]

Identifier: 169833325

GI number: 169833325

Start: 1049422

End: 1051101

Strand: Direct

Name: cisA [H]

Synonym: SPH_1141

Alternate gene names: 169833325

Gene position: 1049422-1051101 (Clockwise)

Preceding gene: 169833806

Following gene: 169834214

Centisome position: 46.73

GC content: 33.69

Gene sequence:

>1680_bases
ATGTCAAAAGAAAAAATAAAAGTATACCTCTATACACGAGTATCTACGTCAATACAGATAGAGGGGTATTCGTTAGGGGC
ACAAAAATCACGAATGAAAGCTTTTGCTATTTACAACGATTATGAAATTGTTGGAGAGTATGAAGATGCCGGGAAGTCTG
GCAAGTCTATTGAAGGTAGAATACAGTTCAATCGAATGATGGAAGATATAAAATCTGGAAAAGATGGAGTATCTTTTGTT
CTTGTGTTTAAGTTATCAAGATTTGCAAGAAATGCCGCTGATGTTCTTTCTACACTTCAGATAATGCAGGATTATGGAGT
TAATCTTATCTGCGTTGAAGATGGCATTGATTCATCTAAAGATGCTGGGAAACTAATGATTTCTGTTTTATCAGCTGTGG
CTGAAATAGAAAGAGAAAACATCCGTATTCAAACAATGGAAGGTTGCATTCAAAAAGCAAGGGAAGGAAAATGGAATGGT
GGCTTTGCTCCGTATGGATATAAACTTGAAGACGGCAAGCTGTTTATAAATGAGGAAGAGGCAGTTGCAATAAGAACGAT
TTTCGACCAGTATGTAAATACTACGATAGGAGCCAATGGGATATCTAAATACTTAGAGAATCATGGAATTAGAAAAATCC
CAAGACAGAATGGTAAGAATCCTTTGTTTGATGCAGGTCTTATAAGAAAGATATTAAAGAATCCTGTATATAATGGGAAA
ATAGCATTTGGAAGAAGAACTTTAGAAAAAGTTCATGGTACAAGAAATGAATATAAGCAGGTTGAACAAGATGAATATCT
AATATCTGAAGGGATACATGAAGCTATAGTTTCCGATGAAGTTTGGCAAGCTGCTCAGGTTAAGCTAAAATCTCAAGCAA
AGAAATATGAGCGTGTGAATAAAGGAAAAGATACACGCACACACTTGCTTTCTGGAATTGTAAAATGCCCGATATGTGGA
GTGGGAATGTTTGGGAACAAGTGTATCAAGAAAAAGAAAGATGGCACAAAGTATAAAGATTTTTATTACTATGGTTGTAA
ACATAGGCAGATGATAAGAGGTCATGAGTGTACATTCAGTAAGCAAATTAGAGAAGAATTGTTAGATGATGCTGTTGCAG
AGGTGATTGTCAAGATAGTAAGTAATCCGAAATTTGCTTCTATGATGCAAGAAAAAATCAACATGAAGGTGGATACCTCT
GAAATAGAAAAAGAAATAGATAATTACCAAAAGGAATTGAGAAAGAGTCATTCTACAAAGTTTAAGCTAATTGAGGAAAT
AGATAATTTAGATGTTGAAGATAAGCATTATAAGAGAAGGAAACAGGATTTAGATGATAGACTATGTCGTATGTATGACA
AAATAGATGAATTAGAATCATCACTAATTGATGCGAAAGCAAAGAAACAGACTATTGAAGCTGAAAAGCTTACAGGAGAT
AACATATATAAGGTTCTGATCTATTTTGATAAGCTCTATAAAGTCATGAATGATGTAGAGCATAGGCAGTTAATTTCAGC
TTTGATTTCTGAAATTCAAGTTTATGAAGAAAAACAATCTAACGGACAATGGCTAAAATCCATTACTTTTAAGCTACCAA
TTATAGAAGAAAATCTCAACATAGGTTTGGATAATGATGAACAAGTTGAATGTGTAAGTTTATTAGAGAAACGTAGTTAA

Upstream 100 bases:

>100_bases
ACGGACTAATAAAAGTGTTATAATATACTTGAAATGATAGTCCAAACTTAAATTAAAAAAATTATATATGATATAGAAAA
ATTATATTGAGGTTAATACT

Downstream 100 bases:

>100_bases
TCCTCAAAAGGTTCCCCAAACCTTTTGAGTCCCACTGACGCATCACGCTGAGGCGGTATCACTGCTTGTACGAGTTGAAG
CATCAGCGAAGTAAAAGTAG

Product: hypothetical protein

Products: NA

Alternate protein names: Stage IV sporulation protein CA [H]

Number of amino acids: Translated: 559; Mature: 558

Protein sequence:

>559_residues
MSKEKIKVYLYTRVSTSIQIEGYSLGAQKSRMKAFAIYNDYEIVGEYEDAGKSGKSIEGRIQFNRMMEDIKSGKDGVSFV
LVFKLSRFARNAADVLSTLQIMQDYGVNLICVEDGIDSSKDAGKLMISVLSAVAEIERENIRIQTMEGCIQKAREGKWNG
GFAPYGYKLEDGKLFINEEEAVAIRTIFDQYVNTTIGANGISKYLENHGIRKIPRQNGKNPLFDAGLIRKILKNPVYNGK
IAFGRRTLEKVHGTRNEYKQVEQDEYLISEGIHEAIVSDEVWQAAQVKLKSQAKKYERVNKGKDTRTHLLSGIVKCPICG
VGMFGNKCIKKKKDGTKYKDFYYYGCKHRQMIRGHECTFSKQIREELLDDAVAEVIVKIVSNPKFASMMQEKINMKVDTS
EIEKEIDNYQKELRKSHSTKFKLIEEIDNLDVEDKHYKRRKQDLDDRLCRMYDKIDELESSLIDAKAKKQTIEAEKLTGD
NIYKVLIYFDKLYKVMNDVEHRQLISALISEIQVYEEKQSNGQWLKSITFKLPIIEENLNIGLDNDEQVECVSLLEKRS

Sequences:

>Translated_559_residues
MSKEKIKVYLYTRVSTSIQIEGYSLGAQKSRMKAFAIYNDYEIVGEYEDAGKSGKSIEGRIQFNRMMEDIKSGKDGVSFV
LVFKLSRFARNAADVLSTLQIMQDYGVNLICVEDGIDSSKDAGKLMISVLSAVAEIERENIRIQTMEGCIQKAREGKWNG
GFAPYGYKLEDGKLFINEEEAVAIRTIFDQYVNTTIGANGISKYLENHGIRKIPRQNGKNPLFDAGLIRKILKNPVYNGK
IAFGRRTLEKVHGTRNEYKQVEQDEYLISEGIHEAIVSDEVWQAAQVKLKSQAKKYERVNKGKDTRTHLLSGIVKCPICG
VGMFGNKCIKKKKDGTKYKDFYYYGCKHRQMIRGHECTFSKQIREELLDDAVAEVIVKIVSNPKFASMMQEKINMKVDTS
EIEKEIDNYQKELRKSHSTKFKLIEEIDNLDVEDKHYKRRKQDLDDRLCRMYDKIDELESSLIDAKAKKQTIEAEKLTGD
NIYKVLIYFDKLYKVMNDVEHRQLISALISEIQVYEEKQSNGQWLKSITFKLPIIEENLNIGLDNDEQVECVSLLEKRS
>Mature_558_residues
SKEKIKVYLYTRVSTSIQIEGYSLGAQKSRMKAFAIYNDYEIVGEYEDAGKSGKSIEGRIQFNRMMEDIKSGKDGVSFVL
VFKLSRFARNAADVLSTLQIMQDYGVNLICVEDGIDSSKDAGKLMISVLSAVAEIERENIRIQTMEGCIQKAREGKWNGG
FAPYGYKLEDGKLFINEEEAVAIRTIFDQYVNTTIGANGISKYLENHGIRKIPRQNGKNPLFDAGLIRKILKNPVYNGKI
AFGRRTLEKVHGTRNEYKQVEQDEYLISEGIHEAIVSDEVWQAAQVKLKSQAKKYERVNKGKDTRTHLLSGIVKCPICGV
GMFGNKCIKKKKDGTKYKDFYYYGCKHRQMIRGHECTFSKQIREELLDDAVAEVIVKIVSNPKFASMMQEKINMKVDTSE
IEKEIDNYQKELRKSHSTKFKLIEEIDNLDVEDKHYKRRKQDLDDRLCRMYDKIDELESSLIDAKAKKQTIEAEKLTGDN
IYKVLIYFDKLYKVMNDVEHRQLISALISEIQVYEEKQSNGQWLKSITFKLPIIEENLNIGLDNDEQVECVSLLEKRS

Specific function: Putative site-specific recombinase having a very important role in sporulation. It probably plays a role in the recombination of spoIIIC and spoIVCB to form sigma K factor [H]

COG id: COG1961

COG function: function code L; Site-specific recombinases, DNA invertase Pin homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 recombinase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011109
- InterPro:   IPR006118
- InterPro:   IPR006119 [H]

Pfam domain/function: PF07508 Recombinase; PF00239 Resolvase [H]

EC number: NA

Molecular weight: Translated: 64251; Mature: 64119

Theoretical pI: Translated: 8.52; Mature: 8.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKEKIKVYLYTRVSTSIQIEGYSLGAQKSRMKAFAIYNDYEIVGEYEDAGKSGKSIEGR
CCCCEEEEEEEEEECCEEEEECEECCCHHHHCEEEEEECCHHEEECHHHCCCCCCCCCHH
IQFNRMMEDIKSGKDGVSFVLVFKLSRFARNAADVLSTLQIMQDYGVNLICVEDGIDSSK
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCC
DAGKLMISVLSAVAEIERENIRIQTMEGCIQKAREGKWNGGFAPYGYKLEDGKLFINEEE
HHHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHHCCCCCCCCCCCCEEECCCEEEECCCH
AVAIRTIFDQYVNTTIGANGISKYLENHGIRKIPRQNGKNPLFDAGLIRKILKNPVYNGK
HHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCE
IAFGRRTLEKVHGTRNEYKQVEQDEYLISEGIHEAIVSDEVWQAAQVKLKSQAKKYERVN
EHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KGKDTRTHLLSGIVKCPICGVGMFGNKCIKKKKDGTKYKDFYYYGCKHRQMIRGHECTFS
CCCHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCCCEEEECCCHHHHHCCCCCCHH
KQIREELLDDAVAEVIVKIVSNPKFASMMQEKINMKVDTSEIEKEIDNYQKELRKSHSTK
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHH
FKLIEEIDNLDVEDKHYKRRKQDLDDRLCRMYDKIDELESSLIDAKAKKQTIEAEKLTGD
HHHHHHHHCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
NIYKVLIYFDKLYKVMNDVEHRQLISALISEIQVYEEKQSNGQWLKSITFKLPIIEENLN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHEECEEEECCCC
IGLDNDEQVECVSLLEKRS
CCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
SKEKIKVYLYTRVSTSIQIEGYSLGAQKSRMKAFAIYNDYEIVGEYEDAGKSGKSIEGR
CCCEEEEEEEEEECCEEEEECEECCCHHHHCEEEEEECCHHEEECHHHCCCCCCCCCHH
IQFNRMMEDIKSGKDGVSFVLVFKLSRFARNAADVLSTLQIMQDYGVNLICVEDGIDSSK
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCC
DAGKLMISVLSAVAEIERENIRIQTMEGCIQKAREGKWNGGFAPYGYKLEDGKLFINEEE
HHHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHHCCCCCCCCCCCCEEECCCEEEECCCH
AVAIRTIFDQYVNTTIGANGISKYLENHGIRKIPRQNGKNPLFDAGLIRKILKNPVYNGK
HHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCE
IAFGRRTLEKVHGTRNEYKQVEQDEYLISEGIHEAIVSDEVWQAAQVKLKSQAKKYERVN
EHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KGKDTRTHLLSGIVKCPICGVGMFGNKCIKKKKDGTKYKDFYYYGCKHRQMIRGHECTFS
CCCHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCCCEEEECCCHHHHHCCCCCCHH
KQIREELLDDAVAEVIVKIVSNPKFASMMQEKINMKVDTSEIEKEIDNYQKELRKSHSTK
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHH
FKLIEEIDNLDVEDKHYKRRKQDLDDRLCRMYDKIDELESSLIDAKAKKQTIEAEKLTGD
HHHHHHHHCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
NIYKVLIYFDKLYKVMNDVEHRQLISALISEIQVYEEKQSNGQWLKSITFKLPIIEENLN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHEECEEEECCCC
IGLDNDEQVECVSLLEKRS
CCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2105293; 7704261; 8969508; 9384377 [H]