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The map label for this gene is yfmC [H]

Identifier: 169833231

GI number: 169833231

Start: 1043593

End: 1044618

Strand: Direct

Name: yfmC [H]

Synonym: SPH_1134

Alternate gene names: 169833231

Gene position: 1043593-1044618 (Clockwise)

Preceding gene: 169833854

Following gene: 169834298

Centisome position: 46.47

GC content: 31.19

Gene sequence:

>1026_bases
ATGAAAAACAAATTTTTTCTAATAGCTATTTTAGCTATGTGTATAGTTTTTAGCGCTTGTTCTTCTAATTCTGTTAAAAA
TGAAGAAAATACTTCTAAAGAGCATGCGCCTGATAAAATAGTTTTAGATCATGCTTTCGGTCAAACTATATTAGATAAAA
AACCTGAAAGAGTTGCAACTATTGCTTGGGGAAATCATGATGTAGCATTAGCTTTAGGAATAGTTCCTGTTGGACTTTCA
AAAGCAAATTACGGTGTAAGTGCTGATAAAGGAGTTTTACCATGGACAGAAGAAAAAATCAAAGAACTAAATGGTAAAGC
TAACCTATTTGACGATTTGGATGGACTTAACTTTGAAGCAATATCAAATTCTAAACCAGATGTTATCTTAGCAGGTTATT
CTGGTATAACTAAAGAAGATTATGACACTCTATCAAAAATTGCTCCTGTAGCAGCATACAAATCTAAACCTTGGCAAACT
TTATGGAGAGATATGATTAGAATTGATTCAAAAGCCTTAGGTATGGAAAAAGAAGGTGATGAGTTAATCAAAAATACTGA
AGCTCGTATATCCAAAGAATTAGAAAAACATCCAGAAATCAAAGGAAAAATCAAAGGAAAAAAAGTATTATTTACTATGA
TTAATGCTGCAGATACATCAAAATTCTGGATTTATACTAGCAAAGATCCAAGAGCAAATTATTTAACAGATTTAGGTCTA
GTTTTCCCTGAATCATTAAAAGAATTTGAGAGTGAAGATAGTTTTGCAAAGGAAATTTCTGCAGAAGAAGCAAATAAGAT
AAATGATGCTGATGTAATCATAACTTATGGTGATGATAAAACTCTTGAAGCTTTACAAAAAGATCCTCTTTTAGGTAAAA
TAAATGCAATTAAAAATGGTGCCGTTGCTGTAATTCCAGATAATACACCGTTAGCAGCCTCATGCACTCCAACACCACTT
TCAATAAACTATACTATTGAAGAATATCTAAATCTTTTAGGAAATGCATGCAAAAATGCGAAATAA

Upstream 100 bases:

>100_bases
CCTTTTTTGAAAAATTATATTATTAAATTTGTAACTGCATCTATTGACAATGATAATTATTATCGATATAATAGACTTGA
AATATGTTCAAGGAGTTTTT

Downstream 100 bases:

>100_bases
AAAACAAATAAACCTAGGCATAATTTTTGTAATCTGCCTAGGTCTTCTTATTACAATATTTTTGTCATTAAAGCTTGGAA
CAAAAGAAATTAATATCAGA

Product: ABC transporter substrate-binding protein - iron transport

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: Ferric-citrate-binding protein [H]

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MKNKFFLIAILAMCIVFSACSSNSVKNEENTSKEHAPDKIVLDHAFGQTILDKKPERVATIAWGNHDVALALGIVPVGLS
KANYGVSADKGVLPWTEEKIKELNGKANLFDDLDGLNFEAISNSKPDVILAGYSGITKEDYDTLSKIAPVAAYKSKPWQT
LWRDMIRIDSKALGMEKEGDELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAADTSKFWIYTSKDPRANYLTDLGL
VFPESLKEFESEDSFAKEISAEEANKINDADVIITYGDDKTLEALQKDPLLGKINAIKNGAVAVIPDNTPLAASCTPTPL
SINYTIEEYLNLLGNACKNAK

Sequences:

>Translated_341_residues
MKNKFFLIAILAMCIVFSACSSNSVKNEENTSKEHAPDKIVLDHAFGQTILDKKPERVATIAWGNHDVALALGIVPVGLS
KANYGVSADKGVLPWTEEKIKELNGKANLFDDLDGLNFEAISNSKPDVILAGYSGITKEDYDTLSKIAPVAAYKSKPWQT
LWRDMIRIDSKALGMEKEGDELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAADTSKFWIYTSKDPRANYLTDLGL
VFPESLKEFESEDSFAKEISAEEANKINDADVIITYGDDKTLEALQKDPLLGKINAIKNGAVAVIPDNTPLAASCTPTPL
SINYTIEEYLNLLGNACKNAK
>Mature_341_residues
MKNKFFLIAILAMCIVFSACSSNSVKNEENTSKEHAPDKIVLDHAFGQTILDKKPERVATIAWGNHDVALALGIVPVGLS
KANYGVSADKGVLPWTEEKIKELNGKANLFDDLDGLNFEAISNSKPDVILAGYSGITKEDYDTLSKIAPVAAYKSKPWQT
LWRDMIRIDSKALGMEKEGDELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAADTSKFWIYTSKDPRANYLTDLGL
VFPESLKEFESEDSFAKEISAEEANKINDADVIITYGDDKTLEALQKDPLLGKINAIKNGAVAVIPDNTPLAASCTPTPL
SINYTIEEYLNLLGNACKNAK

Specific function: Part of the ABC transporter complex yfmCDEF involved in citrate-dependent Fe(3+) import. Binds citrate-dependent Fe(3+) and delivers it to the surface of yfmDE (Probable) [H]

COG id: COG0614

COG function: function code P; ABC-type Fe3+-hydroxamate transport system, periplasmic component

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Fe/B12 periplasmic-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87082411, Length=283, Percent_Identity=24.0282685512367, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002491 [H]

Pfam domain/function: PF01497 Peripla_BP_2 [H]

EC number: NA

Molecular weight: Translated: 37501; Mature: 37501

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50983 FE_B12_PBP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNKFFLIAILAMCIVFSACSSNSVKNEENTSKEHAPDKIVLDHAFGQTILDKKPERVAT
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHCCCCEEEEEHHHCCHHHCCCCCEEEE
IAWGNHDVALALGIVPVGLSKANYGVSADKGVLPWTEEKIKELNGKANLFDDLDGLNFEA
EEECCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCHHCCCCCCEEE
ISNSKPDVILAGYSGITKEDYDTLSKIAPVAAYKSKPWQTLWRDMIRIDSKALGMEKEGD
ECCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCH
ELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAADTSKFWIYTSKDPRANYLTDLGL
HHHHHHHHHHHHHHHHCCCCCEEECCCEEEEEEEECCCCCEEEEEECCCCCCHHHHHHHH
VFPESLKEFESEDSFAKEISAEEANKINDADVIITYGDDKTLEALQKDPLLGKINAIKNG
HCHHHHHHHHCHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHCCCCCEEHHHCCCC
AVAVIPDNTPLAASCTPTPLSINYTIEEYLNLLGNACKNAK
EEEEEECCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKNKFFLIAILAMCIVFSACSSNSVKNEENTSKEHAPDKIVLDHAFGQTILDKKPERVAT
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHCCCCEEEEEHHHCCHHHCCCCCEEEE
IAWGNHDVALALGIVPVGLSKANYGVSADKGVLPWTEEKIKELNGKANLFDDLDGLNFEA
EEECCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCHHCCCCCCEEE
ISNSKPDVILAGYSGITKEDYDTLSKIAPVAAYKSKPWQTLWRDMIRIDSKALGMEKEGD
ECCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCH
ELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAADTSKFWIYTSKDPRANYLTDLGL
HHHHHHHHHHHHHHHHCCCCCEEECCCEEEEEEEECCCCCEEEEEECCCCCCHHHHHHHH
VFPESLKEFESEDSFAKEISAEEANKINDADVIITYGDDKTLEALQKDPLLGKINAIKNG
HCHHHHHHHHCHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHCCCCCEEHHHCCCC
AVAVIPDNTPLAASCTPTPLSINYTIEEYLNLLGNACKNAK
EEEEEECCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9272861; 9384377 [H]