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The map label for this gene is ppnK [H]

Identifier: 169833190

GI number: 169833190

Start: 1091087

End: 1091905

Strand: Direct

Name: ppnK [H]

Synonym: SPH_1189

Alternate gene names: 169833190

Gene position: 1091087-1091905 (Clockwise)

Preceding gene: 169833659

Following gene: 169832712

Centisome position: 48.59

GC content: 41.76

Gene sequence:

>819_bases
ATGAAGAATACAGGTAAACGAATTGATCTGATAGCCAATAGAAAACCGCAGAGTCAAAGGGTTTTGTATGAATTGCGAGA
TCGTTTGAAGAGAAATCAGTTTATACTCAATGATACCAATCCGGATATTGTCATTTCCATTGGCGGGGATGGTATGCTCT
TGTCGGCCTTTCATAAGTACGAAAATCAGCTTGAGAAGGTCCGCTTTATCGGTCTTCACACTGGACATTTGGGCTTCTAT
ACAGATTATCGTGATTTTGAGTTGGACAAGCTAGTGACTAATTTGCAGCTAGATACTGGGGCAAGGGTTTCTTACCCTGT
TCTGAATGTGAAGGTCTTTCTTGAAAATGGTGAAGTTAAGATTTTCAGAGCACTCAACGAAGCCAGCATCCGCAGGTCTG
ATCGAACCATGGTGGCAGATATTGTAATAAATGGTGTTCCCTTTGAACGTTTTCGTGGAGACGGGCTAACAGTTTCGACA
CCGACTGGTAGTACTGCCTATAACAAGTCTCTTGGCGGTGCTGTTTTACACCCTACCATTGAAGCTTTGCAATTAACGGA
AATTGCCAGCCTTAATAATCGTGTCTATCGAACACTGGGCTCTTCCATTATTGTGCCTAAGAAGGATAAGATTGAACTTA
TTCCAACAAGAAACGATTATCATACTATTTCGGTTGACAATAGCGTTTATTCTTTCCGTAATATTGAGCGTATTGAGTAT
CAAATCGCCCATCATAAGATTCACTTTGTCGCGACTCCTAGCCATACCAGTTTCTGGAACCGTGTTAAGGATGCCTTTAT
CGGTGAGGTGGATGAATGA

Upstream 100 bases:

>100_bases
GAAATGGGTGAAATTCGTGATGATATCCAAGAAGCTCAGGCACTTTTTGATCCTTTGAGTAGAAAATTAAATGACGGTGT
AGGAAACAGTGACGATACAG

Downstream 100 bases:

>100_bases
GGTTTGAATTTATCGCAGATGAACATGTCAAGGTTAAGACCTTCTTAAAAAAGCACGAGGTTTCTAAGGGATTGCTGGCC
AAGATTAAGTTTCGAGGTGG

Product: inorganic polyphosphate/ATP-NAD kinase

Products: NA

Alternate protein names: Poly(P)/ATP NAD kinase [H]

Number of amino acids: Translated: 272; Mature: 272

Protein sequence:

>272_residues
MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIVISIGGDGMLLSAFHKYENQLEKVRFIGLHTGHLGFY
TDYRDFELDKLVTNLQLDTGARVSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVST
PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRNDYHTISVDNSVYSFRNIERIEY
QIAHHKIHFVATPSHTSFWNRVKDAFIGEVDE

Sequences:

>Translated_272_residues
MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIVISIGGDGMLLSAFHKYENQLEKVRFIGLHTGHLGFY
TDYRDFELDKLVTNLQLDTGARVSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVST
PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRNDYHTISVDNSVYSFRNIERIEY
QIAHHKIHFVATPSHTSFWNRVKDAFIGEVDE
>Mature_272_residues
MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIVISIGGDGMLLSAFHKYENQLEKVRFIGLHTGHLGFY
TDYRDFELDKLVTNLQLDTGARVSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVST
PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRNDYHTISVDNSVYSFRNIERIEY
QIAHHKIHFVATPSHTSFWNRVKDAFIGEVDE

Specific function: Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus [H]

COG id: COG0061

COG function: function code G; Predicted sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD kinase family [H]

Homologues:

Organism=Escherichia coli, GI1788968, Length=223, Percent_Identity=26.457399103139, Blast_Score=67, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322509, Length=273, Percent_Identity=26.7399267399267, Blast_Score=68, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6325068, Length=163, Percent_Identity=30.6748466257669, Blast_Score=65, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6320794, Length=199, Percent_Identity=26.6331658291457, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016064
- InterPro:   IPR017438
- InterPro:   IPR017437
- InterPro:   IPR002504 [H]

Pfam domain/function: PF01513 NAD_kinase [H]

EC number: =2.7.1.23 [H]

Molecular weight: Translated: 31006; Mature: 31006

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIVISIGGDGMLLSAFHKY
CCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCEEEEECCCCCEEEEECCCCEEHHHHHHH
ENQLEKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGARVSYPVLNVKVFLENGEVK
HHHHHHEEEEEEEECCEEEECCCCCCCHHHHHHHEEECCCCEEEEEEEEEEEEEECCCEE
IFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVSTPTGSTAYNKSLGGAVLHPTI
EEEECCHHHHCCCCCEEEEEEEECCCCHHHCCCCCEEEECCCCCCCCCCCCCCEEECCHH
EALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRNDYHTISVDNSVYSFRNIERIEY
HHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEEEECCCCEEEEEECCCCHHHHCHHHHEE
QIAHHKIHFVATPSHTSFWNRVKDAFIGEVDE
EEEEEEEEEEECCCCHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIVISIGGDGMLLSAFHKY
CCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCEEEEECCCCCEEEEECCCCEEHHHHHHH
ENQLEKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGARVSYPVLNVKVFLENGEVK
HHHHHHEEEEEEEECCEEEECCCCCCCHHHHHHHEEECCCCEEEEEEEEEEEEEECCCEE
IFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVSTPTGSTAYNKSLGGAVLHPTI
EEEECCHHHHCCCCCEEEEEEEECCCCHHHCCCCCEEEECCCCCCCCCCCCCCEEECCHH
EALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRNDYHTISVDNSVYSFRNIERIEY
HHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEEEECCCCEEEEEECCCCHHHHCHHHHEE
QIAHHKIHFVATPSHTSFWNRVKDAFIGEVDE
EEEEEEEEEEECCCCHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA