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The map label for this gene is ycxD [H]

Identifier: 169832988

GI number: 169832988

Start: 1412231

End: 1413502

Strand: Direct

Name: ycxD [H]

Synonym: SPH_1524

Alternate gene names: 169832988

Gene position: 1412231-1413502 (Clockwise)

Preceding gene: 169834400

Following gene: 169834512

Centisome position: 62.89

GC content: 43.0

Gene sequence:

>1272_bases
ATGAAGAAACAAAGCAAGTACAAAGAGGTCGTTTCCTATCTGAAAAATGGTATCGAGTCTGGACGATTTCCGACGGGTAG
TCGCCTGCCTTCTATCCGTCAACTGAGCCTTGACTTTCACTGCAGCAAGGACACCATTCAACGAGCCCTGCTGGAATTAC
GGCACGAACAATACCTCTATGCCAAGCCTCAGAGTGGCTACTATGTATTAGAACAAGGGCAACATCAAGACCTAGAAATC
GAGGTTACCGACGAACATGCCAGTGCCTATGACGATTTCCGACTCTGTGTCAATGAAACCTTGATTGGCCGAGAAAACTA
CCTCTTCAACTACTATGACAATCAAGAAGGATTAGAAGACCTAAGACAGTCCATTCACAAACTCCTCTTTGAGCAAGCTC
TCTACTGCAAGGCTAACCAACTAGTACTGACTTCTGGAACCCAACAAGCCTTGTTTATCCTCTCTCAAATATCCTTTCCT
AGACAAGCCAAGGAAATCTTGGTGGAACAGCCAACCTACCATCGGATGAATCGCCTCTTGATTGCACAGGGGCTGGACTA
TCAAACGATTGAACGAGGCATTGATGGGATTGACTTGGAGGAGCTGGAAGGCCACTTCAAAACAGGAAAAATTAAATTTT
TCTACACCATTCCTAGATTTCACTATCCTCTGGGACATTCCTATTCTGAGCAGGACAAACGATCTATTCTTAACTTAGCT
GCCAAGTATGATGTCTATATCGTAGAGGACGATTATCTGGGTGATTTGGACTCCAAGAAGGGCCAAACCTTCCACTATCT
TGATACAGAGGAGCGTGTCATTTATATCAAGTCCTTCTCGACCAGCCTTTTTCCTGCCCTTCGTATTACAGCACTCATTC
TTCCAAATGCTATCAAAGAAGCATTTGTGGCCTACAAAAATATCCTAGACTACGACAGCAACCTCATTATGCAAAAGGCC
CTGTCACTCTATATTGACAGTCAATTGTTTGAAAAAAATCGTTTGGCTCGCTTGACCAATCATGAATCTTACCAAAAACA
AATCGAGGAAAGGATAACTAAAACACCTTGTCCCCTTCCTCATTATCCCCTACACGATGGTTTATTGCTAGACCTGAGAC
AGTATCCTAAAATCGCCAGTCTCAAACACAGTCAACTGGGCTTGGACTTCTTTGAAGAGGCCTATTTAAGTACCTGTCCT
TATCAATTTGCCAAGGTGTCCCTAGACAATCTGGAAAATGTTTTAAACTATTTAAAAGCAGAATTGGAATGA

Upstream 100 bases:

>100_bases
ATACCACATTTGCCCCTAGATGTGAACGAGAGAAACGCTCTAGACATTGCCAAGAAGGAAAAAAAAGGGTACAATGTAAC
AAAATCAAGGGAGGTCTGGA

Downstream 100 bases:

>100_bases
CATCCAACTCTGCTTTTTCTTATTCTTCAACTTCAGTTAGACTTGCTGCTTTTTCAAGATAGCTTTGGTAAATTCCTTCA
TCCTTAAGTTTTTGGATGAC

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: ORF8 [H]

Number of amino acids: Translated: 423; Mature: 423

Protein sequence:

>423_residues
MKKQSKYKEVVSYLKNGIESGRFPTGSRLPSIRQLSLDFHCSKDTIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEI
EVTDEHASAYDDFRLCVNETLIGRENYLFNYYDNQEGLEDLRQSIHKLLFEQALYCKANQLVLTSGTQQALFILSQISFP
RQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLEELEGHFKTGKIKFFYTIPRFHYPLGHSYSEQDKRSILNLA
AKYDVYIVEDDYLGDLDSKKGQTFHYLDTEERVIYIKSFSTSLFPALRITALILPNAIKEAFVAYKNILDYDSNLIMQKA
LSLYIDSQLFEKNRLARLTNHESYQKQIEERITKTPCPLPHYPLHDGLLLDLRQYPKIASLKHSQLGLDFFEEAYLSTCP
YQFAKVSLDNLENVLNYLKAELE

Sequences:

>Translated_423_residues
MKKQSKYKEVVSYLKNGIESGRFPTGSRLPSIRQLSLDFHCSKDTIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEI
EVTDEHASAYDDFRLCVNETLIGRENYLFNYYDNQEGLEDLRQSIHKLLFEQALYCKANQLVLTSGTQQALFILSQISFP
RQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLEELEGHFKTGKIKFFYTIPRFHYPLGHSYSEQDKRSILNLA
AKYDVYIVEDDYLGDLDSKKGQTFHYLDTEERVIYIKSFSTSLFPALRITALILPNAIKEAFVAYKNILDYDSNLIMQKA
LSLYIDSQLFEKNRLARLTNHESYQKQIEERITKTPCPLPHYPLHDGLLLDLRQYPKIASLKHSQLGLDFFEEAYLSTCP
YQFAKVSLDNLENVLNYLKAELE
>Mature_423_residues
MKKQSKYKEVVSYLKNGIESGRFPTGSRLPSIRQLSLDFHCSKDTIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEI
EVTDEHASAYDDFRLCVNETLIGRENYLFNYYDNQEGLEDLRQSIHKLLFEQALYCKANQLVLTSGTQQALFILSQISFP
RQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLEELEGHFKTGKIKFFYTIPRFHYPLGHSYSEQDKRSILNLA
AKYDVYIVEDDYLGDLDSKKGQTFHYLDTEERVIYIKSFSTSLFPALRITALILPNAIKEAFVAYKNILDYDSNLIMQKA
LSLYIDSQLFEKNRLARLTNHESYQKQIEERITKTPCPLPHYPLHDGLLLDLRQYPKIASLKHSQLGLDFFEEAYLSTCP
YQFAKVSLDNLENVLNYLKAELE

Specific function: Unknown

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790797, Length=331, Percent_Identity=25.3776435045317, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1787710, Length=321, Percent_Identity=26.791277258567, Blast_Score=91, Evalue=1e-19,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 49356; Mature: 49356

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKQSKYKEVVSYLKNGIESGRFPTGSRLPSIRQLSLDFHCSKDTIQRALLELRHEQYLY
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHEEEEEEECCHHHHHHHHHHHHHHHEEE
AKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCVNETLIGRENYLFNYYDNQEGLED
ECCCCCEEEEECCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHH
LRQSIHKLLFEQALYCKANQLVLTSGTQQALFILSQISFPRQAKEILVEQPTYHRMNRLL
HHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHH
IAQGLDYQTIERGIDGIDLEELEGHFKTGKIKFFYTIPRFHYPLGHSYSEQDKRSILNLA
HHCCCCHHHHHCCCCCCCHHHHCCCCCCCCEEEEEECCCEECCCCCCCCHHHHHHHHHHH
AKYDVYIVEDDYLGDLDSKKGQTFHYLDTEERVIYIKSFSTSLFPALRITALILPNAIKE
HHCEEEEEECCCCCCCCCCCCCEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHH
AFVAYKNILDYDSNLIMQKALSLYIDSQLFEKNRLARLTNHESYQKQIEERITKTPCPLP
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCC
HYPLHDGLLLDLRQYPKIASLKHSQLGLDFFEEAYLSTCPYQFAKVSLDNLENVLNYLKA
CCCCCCCCHHHHHHCCCHHCCCHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
ELE
HCC
>Mature Secondary Structure
MKKQSKYKEVVSYLKNGIESGRFPTGSRLPSIRQLSLDFHCSKDTIQRALLELRHEQYLY
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHEEEEEEECCHHHHHHHHHHHHHHHEEE
AKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCVNETLIGRENYLFNYYDNQEGLED
ECCCCCEEEEECCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHH
LRQSIHKLLFEQALYCKANQLVLTSGTQQALFILSQISFPRQAKEILVEQPTYHRMNRLL
HHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHH
IAQGLDYQTIERGIDGIDLEELEGHFKTGKIKFFYTIPRFHYPLGHSYSEQDKRSILNLA
HHCCCCHHHHHCCCCCCCHHHHCCCCCCCCEEEEEECCCEECCCCCCCCHHHHHHHHHHH
AKYDVYIVEDDYLGDLDSKKGQTFHYLDTEERVIYIKSFSTSLFPALRITALILPNAIKE
HHCEEEEEECCCCCCCCCCCCCEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHH
AFVAYKNILDYDSNLIMQKALSLYIDSQLFEKNRLARLTNHESYQKQIEERITKTPCPLP
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCC
HYPLHDGLLLDLRQYPKIASLKHSQLGLDFFEEAYLSTCPYQFAKVSLDNLENVLNYLKA
CCCCCCCCHHHHHHCCCHHCCCHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
ELE
HCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8355609; 8969502; 9384377 [H]