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The map label for this gene is nrdD [H]

Identifier: 169832955

GI number: 169832955

Start: 278906

End: 281113

Strand: Direct

Name: nrdD [H]

Synonym: SPH_0317

Alternate gene names: 169832955

Gene position: 278906-281113 (Clockwise)

Preceding gene: 169833443

Following gene: 169832515

Centisome position: 12.42

GC content: 42.98

Gene sequence:

>2208_bases
ATGATTGCACTAGAAGAAAAAATTACAATTTTGCCAACTCTCTTCGTCGAGAAACGAGATGGGAGACGTGTTGTATTTGA
TGTGGACAAGATTGACAAGGCTCTCCACAAGGCGGCTGACAAGGTTATGGATGTGACACCCCTGGTTGAAAAACGCCTCA
ATGATCTGACTGAGCGAATTATTACAGAAATTCATAGTCGCTTTCCACAGGGAATTAAGATTTACGAAATTCAAAATATC
GTAGAACATGAACTCCTTGAAGCCAAAGAATATGCGCTGGCTGAGGAGTATATTACTTATCGGACACAGAGGGATTTTGA
GCGCTCAAAAGCGACGGATATCAACTTTAGTATTCATAAACTTCTCAACAAAGACCAGACAGTTGTCAATGAAAATGCTA
ATAAAGACAGTGATGTCTTTAACACTCAGCGTGATTTGACAGCAGGGATTGTTGGGAAATCAATCGGACTGCAAATGCTT
CCTAAGCACGTAGCCAATGCCCACCAAAAGGGGGATATCCACTATCACGATTTGGACTACAGTCCCTATACCCCTATGAC
CAACTGCTGTTTGATTGATTTTAAGGGTATGTTGGAAAATGGTTTTAAGATTGGAAATGCAGAGGTAGAGAGTCCCAAGT
CTATCCAGACTGCGACAGCACAGATTTCTCAAATCATTGCCAACGTTGCTTCTAGCCAGTACGGTGGCTGTTCAGCTGAC
CGTATCGATGAAATTTTGGCGCCTTATGCAGAGAAGAACTATCAAAAACATCTCAAAGATGCAGAAGAGTGGGTATTGCC
TGAAAAACGGGAAGATTACGCTTGGAAGAAAACGCAAAAGGACATCTACGATGCCATGCAATCTCTTGAGTATGAAATCA
ATACTCTCTTCACTTCAAATGGACAAACACCTTTTACTTCGTTAGGTTTTGGTCTGGGAACCAGTCGTTTTGAACGAGAA
ATTCAAAAAGCTATTTTAAACATTCGCATCAAGGGTCTTGGTTCAGAACACCGTACGGCTATCTTTCCTAAACTTATCTT
TACGCTTAAAAGAGGCCTCAACTTAGAGGAAGGAACTCCCAACTATGACATCAAGCAGTTGGCTCTAGAGTGTGCAACCA
AGCGGATGTATCCAGACGTCTTGTCTTATGATAAGATTGTTGATTTGACAGGTTCTTTCAAGGTGCCTATGGGTTGCCGT
TCTTTCCTCCAAGGATGGAAGGATGAAAATGGTGTAGAAGTCAATTCAGGTCGCATGAATCTGGGTGTTGTGACGGTTAA
TCTGCCTCGTATTGCTCTTGAGTCTGAAGGTGATATGAATAAGTTCTGGGAAATCTTCAACGAGCGAATGAATATCGCAG
AAGATGCTCTTGTTTACCGTGTCGAACGCACTAAAGAGGCGACACCAGCGAATGCTCCTATCCTTTATCAGTACGGTGCT
TTTGGCCATCGTCTAGGTAAAGAAGAAAGTGTTGACCAGCTCTTTAAGAATCGTCGTGCGACCGTTTCGCTGGGCTATAT
CGGCTTGTATGAAGTAGCGACAGTTTTCTTTGGTAACAGCTGGGAAAGTAATCCAGATGCTAAGGAATTCACGCTAGACA
TCATTCACGATATGAAACGCCGTGTAGAAGAGTGGTCAGACCAATATGGCTACCATTTCTCTATCTACTCAACACCATCC
GAAAGTCTGACAGACCGTTTCTGCCGACTAGATATAGACAAGTTTGGCTCTATTCCTGATATCACAGACAAGGAATACTA
CACCAACTCTTTCCACTACGATGTTCGTAAAAATCCAACACCGTTTGAAAAATTGGACTTTGAGAAAGTCTATCCAGAAG
CAGGTGCGTCAGGTGGTTTCATCCATTATTGTGAGTATCCAGTCCTTCAGCAAAATCCAAAGGCCTTGGAAGCTGTCTGG
GATTATGCTTATGACCGTGTAGGCTATCTAGGCACCAATACTCCGATTGACCGTTGCTACAAGTGTGACTTTGAAGGGGA
TTTTGAACCAACTGAGAGAGGGTTTGCTTGTCCAAACTGTGGCAATAGCGATCCTAAAACAGTAGACGTTGTTAAACGGA
CTTGTGGCTATCTTGGCAATCCTCAAGCAAGACCGATGGTCAACGGGCGTCACAAGGAAATCGCTGCGCGTGTCAAACAT
ATGAATGGTTCAACGATTAAAATAGCTGGGCATCAAGTAACAAATTAG

Upstream 100 bases:

>100_bases
ATTTTTAAAAATTTTAAGATTTTTAACACAAGATATTGATTTTTCTTTTTAGAGTGGTATAATACTTTTTAGAAAGAACA
TTTTAGAAAAGAGCATGCAT

Downstream 100 bases:

>100_bases
AAAGAAATGAAATGGGGAAATATCAACTAGACGATAAGGGGCGCGCACAAGTGACCCGTTATCACGAGAAATACTCTAAA
GGTGGAGCTGGTAAGAAAGA

Product: anaerobic ribonucleoside triphosphate reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 735; Mature: 735

Protein sequence:

>735_residues
MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMDVTPLVEKRLNDLTERIITEIHSRFPQGIKIYEIQNI
VEHELLEAKEYALAEEYITYRTQRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLENGFKIGNAEVESPKSIQTATAQISQIIANVASSQYGGCSAD
RIDEILAPYAEKNYQKHLKDAEEWVLPEKREDYAWKKTQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFERE
IQKAILNIRIKGLGSEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGSFKVPMGCR
SFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERMNIAEDALVYRVERTKEATPANAPILYQYGA
FGHRLGKEESVDQLFKNRRATVSLGYIGLYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSDQYGYHFSIYSTPS
ESLTDRFCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYCEYPVLQQNPKALEAVW
DYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGNSDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKH
MNGSTIKIAGHQVTN

Sequences:

>Translated_735_residues
MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMDVTPLVEKRLNDLTERIITEIHSRFPQGIKIYEIQNI
VEHELLEAKEYALAEEYITYRTQRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLENGFKIGNAEVESPKSIQTATAQISQIIANVASSQYGGCSAD
RIDEILAPYAEKNYQKHLKDAEEWVLPEKREDYAWKKTQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFERE
IQKAILNIRIKGLGSEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGSFKVPMGCR
SFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERMNIAEDALVYRVERTKEATPANAPILYQYGA
FGHRLGKEESVDQLFKNRRATVSLGYIGLYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSDQYGYHFSIYSTPS
ESLTDRFCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYCEYPVLQQNPKALEAVW
DYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGNSDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKH
MNGSTIKIAGHQVTN
>Mature_735_residues
MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMDVTPLVEKRLNDLTERIITEIHSRFPQGIKIYEIQNI
VEHELLEAKEYALAEEYITYRTQRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLENGFKIGNAEVESPKSIQTATAQISQIIANVASSQYGGCSAD
RIDEILAPYAEKNYQKHLKDAEEWVLPEKREDYAWKKTQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFERE
IQKAILNIRIKGLGSEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGSFKVPMGCR
SFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERMNIAEDALVYRVERTKEATPANAPILYQYGA
FGHRLGKEESVDQLFKNRRATVSLGYIGLYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSDQYGYHFSIYSTPS
ESLTDRFCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYCEYPVLQQNPKALEAVW
DYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGNSDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKH
MNGSTIKIAGHQVTN

Specific function: Unknown

COG id: COG1328

COG function: function code F; Oxygen-sensitive ribonucleoside-triphosphate reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glycine radical domain [H]

Homologues:

Organism=Escherichia coli, GI1790686, Length=725, Percent_Identity=52, Blast_Score=759, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005144
- InterPro:   IPR001150
- InterPro:   IPR019777
- InterPro:   IPR012833 [H]

Pfam domain/function: PF03477 ATP-cone; PF01228 Gly_radical [H]

EC number: =1.17.4.2 [H]

Molecular weight: Translated: 83891; Mature: 83891

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: PS51161 ATP_CONE ; PS00850 GLY_RADICAL_1 ; PS51149 GLY_RADICAL_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMDVTPLVEKRLNDLTERI
CCCCCCCCEEEEEEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRTQRDFERSKATDINFSIHK
HHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
LLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQMLPKHVANAHQKGDIHYHDLDY
HCCCCCHHHCCCCCCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCC
SPYTPMTNCCLIDFKGMLENGFKIGNAEVESPKSIQTATAQISQIIANVASSQYGGCSAD
CCCCCCCCEEEEEEHHHHHCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHH
RIDEILAPYAEKNYQKHLKDAEEWVLPEKREDYAWKKTQKDIYDAMQSLEYEINTLFTSN
HHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEEEEECC
GQTPFTSLGFGLGTSRFEREIQKAILNIRIKGLGSEHRTAIFPKLIFTLKRGLNLEEGTP
CCCCHHHHCCCCCHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCC
NYDIKQLALECATKRMYPDVLSYDKIVDLTGSFKVPMGCRSFLQGWKDENGVEVNSGRMN
CCHHHHHHHHHHHHHHCHHHHCCHHHEECCCCCCCCHHHHHHHHCCCCCCCEEECCCEEE
LGVVTVNLPRIALESEGDMNKFWEIFNERMNIAEDALVYRVERTKEATPANAPILYQYGA
EEEEEEECCEEEECCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCEEEECCC
FGHRLGKEESVDQLFKNRRATVSLGYIGLYEVATVFFGNSWESNPDAKEFTLDIIHDMKR
HHHHCCCHHHHHHHHHCCCCEEEECCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
RVEEWSDQYGYHFSIYSTPSESLTDRFCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPT
HHHHHHHCCCEEEEEECCCCHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCEEEECCCCCC
PFEKLDFEKVYPEAGASGGFIHYCEYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCY
CHHHCCHHHHCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHE
KCDFEGDFEPTERGFACPNCGNSDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKH
ECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHH
MNGSTIKIAGHQVTN
CCCCEEEEECCCCCC
>Mature Secondary Structure
MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMDVTPLVEKRLNDLTERI
CCCCCCCCEEEEEEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRTQRDFERSKATDINFSIHK
HHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
LLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQMLPKHVANAHQKGDIHYHDLDY
HCCCCCHHHCCCCCCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCC
SPYTPMTNCCLIDFKGMLENGFKIGNAEVESPKSIQTATAQISQIIANVASSQYGGCSAD
CCCCCCCCEEEEEEHHHHHCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHH
RIDEILAPYAEKNYQKHLKDAEEWVLPEKREDYAWKKTQKDIYDAMQSLEYEINTLFTSN
HHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEEEEECC
GQTPFTSLGFGLGTSRFEREIQKAILNIRIKGLGSEHRTAIFPKLIFTLKRGLNLEEGTP
CCCCHHHHCCCCCHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCC
NYDIKQLALECATKRMYPDVLSYDKIVDLTGSFKVPMGCRSFLQGWKDENGVEVNSGRMN
CCHHHHHHHHHHHHHHCHHHHCCHHHEECCCCCCCCHHHHHHHHCCCCCCCEEECCCEEE
LGVVTVNLPRIALESEGDMNKFWEIFNERMNIAEDALVYRVERTKEATPANAPILYQYGA
EEEEEEECCEEEECCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCEEEECCC
FGHRLGKEESVDQLFKNRRATVSLGYIGLYEVATVFFGNSWESNPDAKEFTLDIIHDMKR
HHHHCCCHHHHHHHHHCCCCEEEECCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
RVEEWSDQYGYHFSIYSTPSESLTDRFCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPT
HHHHHHHCCCEEEEEECCCCHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCEEEECCCCCC
PFEKLDFEKVYPEAGASGGFIHYCEYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCY
CHHHCCHHHHCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHE
KCDFEGDFEPTERGFACPNCGNSDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKH
ECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHH
MNGSTIKIAGHQVTN
CCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8421692; 7610040; 9278503; 8083158; 7852304 [H]