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The map label for this gene is patA [H]

Identifier: 169832566

GI number: 169832566

Start: 110579

End: 111748

Strand: Direct

Name: patA [H]

Synonym: SPH_0135

Alternate gene names: 169832566

Gene position: 110579-111748 (Clockwise)

Preceding gene: 169833678

Following gene: 169832502

Centisome position: 4.92

GC content: 46.15

Gene sequence:

>1170_bases
ATGGACTTAACTAAGCGCTTTAATAAACAGTTAGATAAAATTCAAGTTTCGTTGATTCGTCAGTTTGACCAGGTTATTTC
GGAGATTCCTGGGGTCTTGCGTTTGACCTTGGGGGAACCTGATTTTACAACGCCAGACCATGTCAAGGAGGCGGCCAAGC
GAGCGATTGATCAGAACCAATCCTACTATACAGGGATGAGTGGTCTGCTGACTCTACGTCAGGCAGCTAGTGACTTTGTT
AAGGAAAAGTACCAACTGGACTATGCTCCTGAAAATGAAATCTTGGTTACAATTGGGGCGACAGAGGCTTTATCTGCGAC
TTTGACGGCTATTTTGGAAGAGGGAGACAAGGTGCTCTTGCCAGCTCCTGCTTATCCGGGTTATGAACCGATTGTCAATC
TAGTTGGGGCAGAAATTGTTGAGATTGATACGACTGAAAATGGTTTTGTCTTGACTCCTGAGATGTTGGAGAAGGCCATT
TTGGAGCAGGGTGATAAGCTCAAGGCGGTTATTCTCAACTATCCAGCCAATCCGACAGGAATTACCTACAGTCGAGAGCA
GTTAGAGGCCTTGGCAGCTGTTTTACGCAAGTACGAAATTTTTGTTGTCTGTGATGAGGTTTACTCAGAATTGACCTACA
CAGGCGAAGCCCATGTGTCTCTAGGAACGATGTTGAGAGACCAGGCTATTATTATCAATGGTTTGTCTAAATCGCATGCC
ATGACAGGTTGGCGTTTGGGGCTGATTTTCGCTCCTGCGGCCTTCACAGCCCAGTTAATCAAGAGTCACCAATACTTGGT
CACTGCCGCAAATACCATGGCGCAACATGCTGCGGTAGAAGCCTTGACGGCTGGTAAAAATGATGCGGAGCCCATGAAGA
AGGAATATATCCAGCGTCGGGACTATATCATCGAAAAAATGACTGCTCTTGGTTTTGAGATTATCAAACCAGACGGTGCC
TTCTATATTTTTGCTAAAATTCCAGCGGGCTACAATCAAGACTCCTTTGCTTTTCTGAAGGATTTTGCTCAGAAGAAGGC
CGTTGCCTTTATCCCTGGTGCAGCCTTTGGACGTTACGGGGAAGGCTACGTCCGCCTATCTTATGCAGCCAGCATGGAGA
CTATCAAAGAAGCCATGAAACGACTTGAGGAGTACATGAGAGAAGCATGA

Upstream 100 bases:

>100_bases
AAAGTAAAATAGAAAGTGGAAAGCTATTCTCTAATGTATTTTTGCGGTCGGGGGGCTTTTGTAGTATAATAGAGATACGT
TTTGAAAGTAGGAGGTATCT

Downstream 100 bases:

>100_bases
TTCAGTCTATCACGAGTCAAGGCTTGGTGCTTTACAATCGCAATTTTCGTGAGGATGACAAGCTCGTCAAAATTTTTACA
GAGCAGGTTGGCAAACGCAT

Product: aromatic amino acid aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MDLTKRFNKQLDKIQVSLIRQFDQVISEIPGVLRLTLGEPDFTTPDHVKEAAKRAIDQNQSYYTGMSGLLTLRQAASDFV
KEKYQLDYAPENEILVTIGATEALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAI
LEQGDKLKAVILNYPANPTGITYSREQLEALAAVLRKYEIFVVCDEVYSELTYTGEAHVSLGTMLRDQAIIINGLSKSHA
MTGWRLGLIFAPAAFTAQLIKSHQYLVTAANTMAQHAAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGA
FYIFAKIPAGYNQDSFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA

Sequences:

>Translated_389_residues
MDLTKRFNKQLDKIQVSLIRQFDQVISEIPGVLRLTLGEPDFTTPDHVKEAAKRAIDQNQSYYTGMSGLLTLRQAASDFV
KEKYQLDYAPENEILVTIGATEALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAI
LEQGDKLKAVILNYPANPTGITYSREQLEALAAVLRKYEIFVVCDEVYSELTYTGEAHVSLGTMLRDQAIIINGLSKSHA
MTGWRLGLIFAPAAFTAQLIKSHQYLVTAANTMAQHAAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGA
FYIFAKIPAGYNQDSFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA
>Mature_389_residues
MDLTKRFNKQLDKIQVSLIRQFDQVISEIPGVLRLTLGEPDFTTPDHVKEAAKRAIDQNQSYYTGMSGLLTLRQAASDFV
KEKYQLDYAPENEILVTIGATEALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAI
LEQGDKLKAVILNYPANPTGITYSREQLEALAAVLRKYEIFVVCDEVYSELTYTGEAHVSLGTMLRDQAIIINGLSKSHA
MTGWRLGLIFAPAAFTAQLIKSHQYLVTAANTMAQHAAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGA
FYIFAKIPAGYNQDSFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713256, Length=405, Percent_Identity=29.3827160493827, Blast_Score=163, Evalue=3e-40,
Organism=Homo sapiens, GI56713254, Length=405, Percent_Identity=29.3827160493827, Blast_Score=163, Evalue=3e-40,
Organism=Homo sapiens, GI95147551, Length=415, Percent_Identity=25.0602409638554, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI169881279, Length=415, Percent_Identity=25.0602409638554, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI169881281, Length=413, Percent_Identity=22.0338983050847, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI4507369, Length=382, Percent_Identity=21.9895287958115, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI187936925, Length=363, Percent_Identity=23.6914600550964, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI14211921, Length=363, Percent_Identity=23.6914600550964, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI149944424, Length=378, Percent_Identity=21.4285714285714, Blast_Score=80, Evalue=2e-15,
Organism=Escherichia coli, GI1788722, Length=360, Percent_Identity=30.2777777777778, Blast_Score=181, Evalue=8e-47,
Organism=Escherichia coli, GI1786816, Length=374, Percent_Identity=29.9465240641711, Blast_Score=177, Evalue=1e-45,
Organism=Escherichia coli, GI1788627, Length=372, Percent_Identity=26.6129032258064, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1787909, Length=396, Percent_Identity=23.2323232323232, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1790797, Length=387, Percent_Identity=22.9974160206718, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787710, Length=282, Percent_Identity=23.4042553191489, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71994476, Length=407, Percent_Identity=27.2727272727273, Blast_Score=124, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI71994472, Length=407, Percent_Identity=27.2727272727273, Blast_Score=124, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17567663, Length=373, Percent_Identity=24.9329758713137, Blast_Score=117, Evalue=8e-27,
Organism=Caenorhabditis elegans, GI17567369, Length=395, Percent_Identity=25.0632911392405, Blast_Score=109, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6322401, Length=332, Percent_Identity=26.8072289156627, Blast_Score=110, Evalue=4e-25,
Organism=Saccharomyces cerevisiae, GI6320317, Length=411, Percent_Identity=22.8710462287105, Blast_Score=79, Evalue=9e-16,
Organism=Saccharomyces cerevisiae, GI6323118, Length=372, Percent_Identity=23.6559139784946, Blast_Score=77, Evalue=7e-15,
Organism=Drosophila melanogaster, GI28573069, Length=386, Percent_Identity=27.720207253886, Blast_Score=139, Evalue=3e-33,
Organism=Drosophila melanogaster, GI24646114, Length=386, Percent_Identity=27.720207253886, Blast_Score=139, Evalue=3e-33,
Organism=Drosophila melanogaster, GI28573067, Length=386, Percent_Identity=27.720207253886, Blast_Score=139, Evalue=3e-33,
Organism=Drosophila melanogaster, GI28573065, Length=386, Percent_Identity=27.720207253886, Blast_Score=139, Evalue=3e-33,
Organism=Drosophila melanogaster, GI18859735, Length=376, Percent_Identity=21.5425531914894, Blast_Score=96, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24641770, Length=452, Percent_Identity=23.2300884955752, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24641760, Length=452, Percent_Identity=23.2300884955752, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24641768, Length=452, Percent_Identity=23.2300884955752, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24641766, Length=452, Percent_Identity=23.2300884955752, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24641764, Length=452, Percent_Identity=23.2300884955752, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI45551451, Length=452, Percent_Identity=23.2300884955752, Blast_Score=72, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.-

Molecular weight: Translated: 43200; Mature: 43200

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLTKRFNKQLDKIQVSLIRQFDQVISEIPGVLRLTLGEPDFTTPDHVKEAAKRAIDQNQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCC
SYYTGMSGLLTLRQAASDFVKEKYQLDYAPENEILVTIGATEALSATLTAILEEGDKVLL
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCHHHHHHHHHHHHHCCCEEEE
PAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAILEQGDKLKAVILNYPANPTG
ECCCCCCHHHHHHHHCCEEEEEECCCCCEEECHHHHHHHHHCCCCCEEEEEEECCCCCCC
ITYSREQLEALAAVLRKYEIFVVCDEVYSELTYTGEAHVSLGTMLRDQAIIINGLSKSHA
CCCCHHHHHHHHHHHHHHEEEEEEHHHHHHHCCCCCCCEEHHHHHHCCEEEEECCCCHHC
MTGWRLGLIFAPAAFTAQLIKSHQYLVTAANTMAQHAAVEALTAGKNDAEPMKKEYIQRR
CCCEEEHEEECCHHHHHHHHHCCHHEEEHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
DYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQDSFAFLKDFAQKKAVAFIPGAAFGRYG
HHHHHHHHHCCEEEECCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCEEEECCHHCCCCC
EGYVRLSYAASMETIKEAMKRLEEYMREA
CCEEEEEHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDLTKRFNKQLDKIQVSLIRQFDQVISEIPGVLRLTLGEPDFTTPDHVKEAAKRAIDQNQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCC
SYYTGMSGLLTLRQAASDFVKEKYQLDYAPENEILVTIGATEALSATLTAILEEGDKVLL
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCHHHHHHHHHHHHHCCCEEEE
PAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAILEQGDKLKAVILNYPANPTG
ECCCCCCHHHHHHHHCCEEEEEECCCCCEEECHHHHHHHHHCCCCCEEEEEEECCCCCCC
ITYSREQLEALAAVLRKYEIFVVCDEVYSELTYTGEAHVSLGTMLRDQAIIINGLSKSHA
CCCCHHHHHHHHHHHHHHEEEEEEHHHHHHHCCCCCCCEEHHHHHHCCEEEEECCCCHHC
MTGWRLGLIFAPAAFTAQLIKSHQYLVTAANTMAQHAAVEALTAGKNDAEPMKKEYIQRR
CCCEEEHEEECCHHHHHHHHHCCHHEEEHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
DYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQDSFAFLKDFAQKKAVAFIPGAAFGRYG
HHHHHHHHHCCEEEECCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCEEEECCHHCCCCC
EGYVRLSYAASMETIKEAMKRLEEYMREA
CCEEEEEHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 2104615 [H]