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The map label for this gene is frr [H]

Identifier: 169832481

GI number: 169832481

Start: 969582

End: 970139

Strand: Direct

Name: frr [H]

Synonym: SPH_1049

Alternate gene names: 169832481

Gene position: 969582-970139 (Clockwise)

Preceding gene: 169832939

Following gene: 169834062

Centisome position: 43.18

GC content: 42.29

Gene sequence:

>558_bases
ATGGCTAACGTAATTATTGAAAAAGCTAAAGAGAGAATGACCCAGTCTCACCAATCACTTGCTCGTGAATTTGGTGGTAT
CCGTGCTGGTCGTGCCAATGCAAGCTTGCTTGACCGTGTACATGTAGAATACTATGGAGTCGAAACTCCTCTTAACCAAA
TCGCTTCAATTACGATTCCAGAAGCGCGTGTTTTGTTGGTAACACCATTTGACAAGTCTTCATTGAAAGACATCGAACGT
GCCTTGAACGCTTCTGATCTTGGTATCACACCGGCTAATGACGGTTCTGTGATTCGCTTGGTTATCCCAGCTCTTACAGA
AGAAACTCGTCGTGACCTTGCTAAAGAAGTGAAGAAGGTCGGCGAAAATGCTAAAGTGGCTGTCCGCAATATCCGTCGCG
ATGCTATGGACGAAGCTAAGAAACAAGAAAAAGCAAAAGAAATCACTGAAGACGAATTGAAGACTCTTGAAAAAGATATT
CAAAAAGTAACAGACGATGCTGTTAAACACATCGACGATATGACTGCCAACAAAGAGAAAGAACTTTTGGAAGTCTAA

Upstream 100 bases:

>100_bases
TCAACATGAACCAATCAGGCAACATCAAACGTGTCGTATTTGGTGAAAATATCGGAACAACAGTTTCAAATAATATCGAA
GAAAAGGAATAAGAAAGAAT

Downstream 100 bases:

>100_bases
AAATAAACAGAAAAACTCAGTTGGCATTGCTGGCTGAGTTTTATTCGAAAGAAGGAAATATGAATACAAATCTTGCAAGT
TTTATCGTTGGACTGATCAT

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor [H]

Number of amino acids: Translated: 185; Mature: 184

Protein sequence:

>185_residues
MANVIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRVHVEYYGVETPLNQIASITIPEARVLLVTPFDKSSLKDIER
ALNASDLGITPANDGSVIRLVIPALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDI
QKVTDDAVKHIDDMTANKEKELLEV

Sequences:

>Translated_185_residues
MANVIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRVHVEYYGVETPLNQIASITIPEARVLLVTPFDKSSLKDIER
ALNASDLGITPANDGSVIRLVIPALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDI
QKVTDDAVKHIDDMTANKEKELLEV
>Mature_184_residues
ANVIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRVHVEYYGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERA
LNASDLGITPANDGSVIRLVIPALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDIQ
KVTDDAVKHIDDMTANKEKELLEV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another [H]

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family [H]

Homologues:

Organism=Homo sapiens, GI20270317, Length=180, Percent_Identity=30, Blast_Score=74, Evalue=9e-14,
Organism=Homo sapiens, GI291042689, Length=187, Percent_Identity=29.4117647058824, Blast_Score=71, Evalue=6e-13,
Organism=Escherichia coli, GI1786368, Length=185, Percent_Identity=45.945945945946, Blast_Score=157, Evalue=3e-40,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002661
- InterPro:   IPR015998 [H]

Pfam domain/function: PF01765 RRF [H]

EC number: NA

Molecular weight: Translated: 20657; Mature: 20526

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANVIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRVHVEYYGVETPLNQIASITIP
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHCCCC
EARVLLVTPFDKSSLKDIERALNASDLGITPANDGSVIRLVIPALTEETRRDLAKEVKKV
CCEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHH
GENAKVAVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDIQKVTDDAVKHIDDMTANKEK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
ELLEV
HHHCC
>Mature Secondary Structure 
ANVIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRVHVEYYGVETPLNQIASITIP
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHCCCC
EARVLLVTPFDKSSLKDIERALNASDLGITPANDGSVIRLVIPALTEETRRDLAKEVKKV
CCEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHH
GENAKVAVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDIQKVTDDAVKHIDDMTANKEK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
ELLEV
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA