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The map label for this gene is pyc [H]

Identifier: 169825269

GI number: 169825269

Start: 1742752

End: 1746171

Strand: Direct

Name: pyc [H]

Synonym: FMG_1572

Alternate gene names: 169825269

Gene position: 1742752-1746171 (Clockwise)

Preceding gene: 169825268

Following gene: 169825271

Centisome position: 96.95

GC content: 39.3

Gene sequence:

>3420_bases
ATGGATAAAATAAAAAAACTTCTTGTGGCAAACCGTGGCGAAATTGCTATAAGAATTTTCAGAGCTTGTAGTGAGCTTGG
AATAAGAAGCGTTGCGATTTACAGCGAAGAGGACAAGACTTCCCTTTTCAGAACAAAGGCTGACGAATCGTATTTGATAA
AAGATGCGGCATCACCTTTGTCGAGTTATTTAGATATCGAAAAAATCATTGCGATTGCAAAATCCAAACACTGCGATGCG
ATTCATCCGGGTTATGGATTTTTGAGTGAAAATGCAGAATTTGCGAGACGTTGCAGGGAAAACGGAATTATTTTCGTGGG
TCCTGACGAATCCGTTCTACATAGTTTAGGTGACAAGGTCCAATCGAAGTTAGTTGCCAAGAAAGCCGGCGTACAAACTA
TCGAGGGCGTGGAGACTCCTATCAGAAATAAAAATGAAGCATTGGAAATCGCAAACCAAATCGGCTATCCAGTTATGGTA
AAAGCTTGTGCTGGTGGTGGCGGACGTGGAATGAGAATTGTCGAAAAAGAATCTGATTTGATGAGTTCTTTCGTCAGCGC
GCAAAACGAATCCAAGAAGGCTTTCGGATCAGACGATATGTTTATCGAAAAATACATCCGCAACCCAAAACACATTGAGG
TGCAAATCATAGCCGACAATCACGGAAATATTCTTCACTTATACGAGAGGGATTGTTCCATTCAAAGACGTCACCAAAAA
GTTGTTGAATTTGCTCCTGCATTTTCGATTTCAGAAAAGACAAAAAACGAACTTCACAACGATGCCATCAAAATCTGCAA
GGAAGTTGGCTACACAAACGCCGGTACTGTGGAATTTTTGGTGGACGAAGATGAAAACCACTATTTTATCGAAGTAAACC
CAAGAGTTCAAGTAGAACACACAGTTAGTGAGCTTATCACTGGAATTGATATCGTTCAAACTCAAATTCTGATTGCAGAC
GGCAAAAGTTTTGATTCTGATGAGATAGGAATTTATTCACAAGACGATATCCACACAAATGGTTACGCAATCCAATGCCG
TATTACGACAGAAGATCCTGCGAATAATTTCATGCCTGACACAGGTAAGATTGATTTGTATCGTACAAGTTCCGGATTCG
GCGTGAGACTTGACGGTGGCAATGGATTCACAGGCTCAGTAATCACACCATATTACGATTCGCTTTTGGTTAAAATCACT
GCCTTCTCCAGAACATTCAACGACACAATCAACAAAGCAATCCGTGCTTTGAGAGAAACGAAAATCAGCGGCGTGAAGAC
AAATATCGGCTTCATCATCAATGTTCTAAACACAGAAGAATTCCACAAGGGAACTTGTGACACGGGATTTATCTCCAAAA
ACCCTGAACTTTTCGACATCAAACCATCAACTGATAAAGAGCTTAAAGTGTTGAATTTCATCAGTGAACGCTCCATTAAT
AACGACAAAAAAGATTACAACATTCCACAAATACCAGAATTTACCAAGACAAATTCTACAGGAACCAAAGATATTTTCGA
AGAAAAAGGCGCCAAGGGACTTAGCGATTGGATTTTGAACCAAGATAAACTTCTAATCACTGATACTACACTAAGAGATG
CGCACCAATCATTGATGGCGACACGAATGAGAACAAGAGATATGCTTCCTATCGCAGAAGCTACCAATGAATTGATGAAG
GACTTGTTCAGTTTGGAAATGTGGGGTGGCGCAACATTTGACGTAAGCTACAGATTTCTGAAGGAAGATCCTTGGATTAG
ACTACAAGAACTTCGCAAAAGAATTCCAAACATTTTATTCCAAATGTTACTTCGTGGAAACAACACCGTAGGATACAAAA
ATTACCCAGATAATGTCGTGGTTAAATTTGTACAAAAAGCCGCAGAAAACGGAATCGACGTGTTCAGAGTATTCGATTCG
CTAAACTACATCGACGGAATGAGACTTGCGTGTGACAGCGTACTTGAACAAGGAAAAATCTTGGAAGCAACGCTTTGCTA
CACAGGTGACATTTTGGACGAAACAAGAGACAAATACTCACTAGAATATTACGTGAAAAAAGCAAAGGAACTAGAATCCA
TCGGCGCAAATATTATCGCAATCAAAGACATGAGCGCACTCTTAAAACCATACGCCGCAACGAAGCTAATTTCAGCATTG
AAAAACGAAATTTCTGTTCCGATTCATTTGCACACACACGACACCACAGGAAACGGAGTCGCTACAATAATCAACGCTTG
TGAATCTGGAGTTGACATAGTTGACACTTGCTTCAACTCAATGAGTTCACTCACAAGTCAACCTGCACTCAACTCAGTCG
TAGCAGCTCTTGAAAACACTCCACGTCAAACGGGAATCAGCCTTTCGAACTGTGACAAAATCAGCAACTACTACAAAGAC
GTTCGCTCATACTACTCACAATTTGAGAGCGATTTGAAAAGTGGTACAACAGAAATTTATCGCTACGAAATTCCTGGAGG
ACAATATTCCAACCTCAAACCACAAGTAGAATCGTTCGGACTTGGAGAAAAATTCGACGAAGTAAAATTAATGTACAAAA
AAGTCAACGACATGCTAGGTGACATCATCAAAGTTACACCATCATCCAAAATGGTCGGAGACATGGCTATATTCATGGTG
GCAAATGGACTCACTCCAGAAAATATATACGAAAAAGGCAAAAACCTCGACTACCCAGACTCTGTAATATCATTTTTCAA
AGGAATGATGGGACAACCTGAACGTGGATTCAACGAAAAATTACAAAAAATCGTACTAAAAGATGAAAAGCCAATCACAA
AAAGAGCTGGACTTTACATCGACCCATTTGATTTTGAAAAAGACAAAAAAGATTTAGAAGACAAATACAAAATGGAATTC
GACGAAAAAGACATCATCTCACACGCACTTTATCCAAAAGTATTCGAAGAATACATTGACTACAGAAAAACAAAAGGCAA
CTTCACTTACATGGACACTCCGACATTCTTCGAAGGAATAAACGAAAAAGAAACAGTCGAAGTTCCAATAGAAGAAGGCA
AAATCCTCATCATCAAACTAATAGAAAAAGGAAGATTGGAAAAAGACGGCTACCGAAACTTCACTTATGAAGTCAACGGA
AACAGACGTGAAGTAAAAGTGTTCGATGAATCTGCAAAAATCACTGAACGTGAAGAAGACAACCTATCAGTAGCAGATCC
TAACAACGACAAAGAAATCGGAGCATCAATTCCAGGAAGAGTCGTAAAAGTTCTAGTCAAAGAAAACGACAAAGTATCAG
TCAACGACCCATTAGTAGTAGTAGAAGCCATGAAAATGGAAACCAACATACTATCCAAATCAGAAGGAATTGTAAAATCA
ATCCTAATCAAAGAAAATGACACCATCGACACAGACCAACTTTTAATAGTTTTGGAATAA

Upstream 100 bases:

>100_bases
GCAAGATTTATTATCACGAGGCTTATCGTGTAGATGATTATGCGATTGAATTGTTAGACCGAAATAATATTGAATATGTC
CAAATTTAAAGAGGTGTAAT

Downstream 100 bases:

>100_bases
AAAAATGGATTGTAGAGTCAAATCTACAATCCTATTTTATTTTTGAAATAGTAAATGCTTTCTTTAAGTGGTTTATATTT
TAATGTAGCAACTTCCTCGT

Product: pyruvate carboxylase

Products: NA

Alternate protein names: Pyruvic carboxylase; PYC [H]

Number of amino acids: Translated: 1139; Mature: 1139

Protein sequence:

>1139_residues
MDKIKKLLVANRGEIAIRIFRACSELGIRSVAIYSEEDKTSLFRTKADESYLIKDAASPLSSYLDIEKIIAIAKSKHCDA
IHPGYGFLSENAEFARRCRENGIIFVGPDESVLHSLGDKVQSKLVAKKAGVQTIEGVETPIRNKNEALEIANQIGYPVMV
KACAGGGGRGMRIVEKESDLMSSFVSAQNESKKAFGSDDMFIEKYIRNPKHIEVQIIADNHGNILHLYERDCSIQRRHQK
VVEFAPAFSISEKTKNELHNDAIKICKEVGYTNAGTVEFLVDEDENHYFIEVNPRVQVEHTVSELITGIDIVQTQILIAD
GKSFDSDEIGIYSQDDIHTNGYAIQCRITTEDPANNFMPDTGKIDLYRTSSGFGVRLDGGNGFTGSVITPYYDSLLVKIT
AFSRTFNDTINKAIRALRETKISGVKTNIGFIINVLNTEEFHKGTCDTGFISKNPELFDIKPSTDKELKVLNFISERSIN
NDKKDYNIPQIPEFTKTNSTGTKDIFEEKGAKGLSDWILNQDKLLITDTTLRDAHQSLMATRMRTRDMLPIAEATNELMK
DLFSLEMWGGATFDVSYRFLKEDPWIRLQELRKRIPNILFQMLLRGNNTVGYKNYPDNVVVKFVQKAAENGIDVFRVFDS
LNYIDGMRLACDSVLEQGKILEATLCYTGDILDETRDKYSLEYYVKKAKELESIGANIIAIKDMSALLKPYAATKLISAL
KNEISVPIHLHTHDTTGNGVATIINACESGVDIVDTCFNSMSSLTSQPALNSVVAALENTPRQTGISLSNCDKISNYYKD
VRSYYSQFESDLKSGTTEIYRYEIPGGQYSNLKPQVESFGLGEKFDEVKLMYKKVNDMLGDIIKVTPSSKMVGDMAIFMV
ANGLTPENIYEKGKNLDYPDSVISFFKGMMGQPERGFNEKLQKIVLKDEKPITKRAGLYIDPFDFEKDKKDLEDKYKMEF
DEKDIISHALYPKVFEEYIDYRKTKGNFTYMDTPTFFEGINEKETVEVPIEEGKILIIKLIEKGRLEKDGYRNFTYEVNG
NRREVKVFDESAKITEREEDNLSVADPNNDKEIGASIPGRVVKVLVKENDKVSVNDPLVVVEAMKMETNILSKSEGIVKS
ILIKENDTIDTDQLLIVLE

Sequences:

>Translated_1139_residues
MDKIKKLLVANRGEIAIRIFRACSELGIRSVAIYSEEDKTSLFRTKADESYLIKDAASPLSSYLDIEKIIAIAKSKHCDA
IHPGYGFLSENAEFARRCRENGIIFVGPDESVLHSLGDKVQSKLVAKKAGVQTIEGVETPIRNKNEALEIANQIGYPVMV
KACAGGGGRGMRIVEKESDLMSSFVSAQNESKKAFGSDDMFIEKYIRNPKHIEVQIIADNHGNILHLYERDCSIQRRHQK
VVEFAPAFSISEKTKNELHNDAIKICKEVGYTNAGTVEFLVDEDENHYFIEVNPRVQVEHTVSELITGIDIVQTQILIAD
GKSFDSDEIGIYSQDDIHTNGYAIQCRITTEDPANNFMPDTGKIDLYRTSSGFGVRLDGGNGFTGSVITPYYDSLLVKIT
AFSRTFNDTINKAIRALRETKISGVKTNIGFIINVLNTEEFHKGTCDTGFISKNPELFDIKPSTDKELKVLNFISERSIN
NDKKDYNIPQIPEFTKTNSTGTKDIFEEKGAKGLSDWILNQDKLLITDTTLRDAHQSLMATRMRTRDMLPIAEATNELMK
DLFSLEMWGGATFDVSYRFLKEDPWIRLQELRKRIPNILFQMLLRGNNTVGYKNYPDNVVVKFVQKAAENGIDVFRVFDS
LNYIDGMRLACDSVLEQGKILEATLCYTGDILDETRDKYSLEYYVKKAKELESIGANIIAIKDMSALLKPYAATKLISAL
KNEISVPIHLHTHDTTGNGVATIINACESGVDIVDTCFNSMSSLTSQPALNSVVAALENTPRQTGISLSNCDKISNYYKD
VRSYYSQFESDLKSGTTEIYRYEIPGGQYSNLKPQVESFGLGEKFDEVKLMYKKVNDMLGDIIKVTPSSKMVGDMAIFMV
ANGLTPENIYEKGKNLDYPDSVISFFKGMMGQPERGFNEKLQKIVLKDEKPITKRAGLYIDPFDFEKDKKDLEDKYKMEF
DEKDIISHALYPKVFEEYIDYRKTKGNFTYMDTPTFFEGINEKETVEVPIEEGKILIIKLIEKGRLEKDGYRNFTYEVNG
NRREVKVFDESAKITEREEDNLSVADPNNDKEIGASIPGRVVKVLVKENDKVSVNDPLVVVEAMKMETNILSKSEGIVKS
ILIKENDTIDTDQLLIVLE
>Mature_1139_residues
MDKIKKLLVANRGEIAIRIFRACSELGIRSVAIYSEEDKTSLFRTKADESYLIKDAASPLSSYLDIEKIIAIAKSKHCDA
IHPGYGFLSENAEFARRCRENGIIFVGPDESVLHSLGDKVQSKLVAKKAGVQTIEGVETPIRNKNEALEIANQIGYPVMV
KACAGGGGRGMRIVEKESDLMSSFVSAQNESKKAFGSDDMFIEKYIRNPKHIEVQIIADNHGNILHLYERDCSIQRRHQK
VVEFAPAFSISEKTKNELHNDAIKICKEVGYTNAGTVEFLVDEDENHYFIEVNPRVQVEHTVSELITGIDIVQTQILIAD
GKSFDSDEIGIYSQDDIHTNGYAIQCRITTEDPANNFMPDTGKIDLYRTSSGFGVRLDGGNGFTGSVITPYYDSLLVKIT
AFSRTFNDTINKAIRALRETKISGVKTNIGFIINVLNTEEFHKGTCDTGFISKNPELFDIKPSTDKELKVLNFISERSIN
NDKKDYNIPQIPEFTKTNSTGTKDIFEEKGAKGLSDWILNQDKLLITDTTLRDAHQSLMATRMRTRDMLPIAEATNELMK
DLFSLEMWGGATFDVSYRFLKEDPWIRLQELRKRIPNILFQMLLRGNNTVGYKNYPDNVVVKFVQKAAENGIDVFRVFDS
LNYIDGMRLACDSVLEQGKILEATLCYTGDILDETRDKYSLEYYVKKAKELESIGANIIAIKDMSALLKPYAATKLISAL
KNEISVPIHLHTHDTTGNGVATIINACESGVDIVDTCFNSMSSLTSQPALNSVVAALENTPRQTGISLSNCDKISNYYKD
VRSYYSQFESDLKSGTTEIYRYEIPGGQYSNLKPQVESFGLGEKFDEVKLMYKKVNDMLGDIIKVTPSSKMVGDMAIFMV
ANGLTPENIYEKGKNLDYPDSVISFFKGMMGQPERGFNEKLQKIVLKDEKPITKRAGLYIDPFDFEKDKKDLEDKYKMEF
DEKDIISHALYPKVFEEYIDYRKTKGNFTYMDTPTFFEGINEKETVEVPIEEGKILIIKLIEKGRLEKDGYRNFTYEVNG
NRREVKVFDESAKITEREEDNLSVADPNNDKEIGASIPGRVVKVLVKENDKVSVNDPLVVVEAMKMETNILSKSEGIVKS
ILIKENDTIDTDQLLIVLE

Specific function: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second, leading to oxaloacetate production. Fulfills an anaplerotic functi

COG id: COG1038

COG function: function code C; Pyruvate carboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI106049528, Length=1150, Percent_Identity=46.8695652173913, Blast_Score=1081, Evalue=0.0,
Organism=Homo sapiens, GI106049295, Length=1150, Percent_Identity=46.8695652173913, Blast_Score=1081, Evalue=0.0,
Organism=Homo sapiens, GI106049292, Length=1150, Percent_Identity=46.8695652173913, Blast_Score=1081, Evalue=0.0,
Organism=Homo sapiens, GI116805327, Length=452, Percent_Identity=43.3628318584071, Blast_Score=389, Evalue=1e-107,
Organism=Homo sapiens, GI189095269, Length=449, Percent_Identity=43.4298440979955, Blast_Score=370, Evalue=1e-102,
Organism=Homo sapiens, GI65506442, Length=449, Percent_Identity=43.4298440979955, Blast_Score=370, Evalue=1e-102,
Organism=Homo sapiens, GI295821183, Length=449, Percent_Identity=43.4298440979955, Blast_Score=370, Evalue=1e-102,
Organism=Homo sapiens, GI38679960, Length=509, Percent_Identity=30.4518664047151, Blast_Score=244, Evalue=3e-64,
Organism=Homo sapiens, GI38679977, Length=509, Percent_Identity=30.4518664047151, Blast_Score=244, Evalue=3e-64,
Organism=Homo sapiens, GI38679967, Length=509, Percent_Identity=30.4518664047151, Blast_Score=244, Evalue=3e-64,
Organism=Homo sapiens, GI38679974, Length=509, Percent_Identity=30.4518664047151, Blast_Score=244, Evalue=3e-64,
Organism=Homo sapiens, GI38679971, Length=509, Percent_Identity=30.4518664047151, Blast_Score=244, Evalue=4e-64,
Organism=Homo sapiens, GI134142062, Length=508, Percent_Identity=30.9055118110236, Blast_Score=238, Evalue=2e-62,
Organism=Escherichia coli, GI1789654, Length=453, Percent_Identity=43.7086092715232, Blast_Score=366, Evalue=1e-102,
Organism=Caenorhabditis elegans, GI17562816, Length=1148, Percent_Identity=47.3867595818815, Blast_Score=1089, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71987519, Length=498, Percent_Identity=39.5582329317269, Blast_Score=357, Evalue=2e-98,
Organism=Caenorhabditis elegans, GI17567343, Length=472, Percent_Identity=38.3474576271186, Blast_Score=329, Evalue=4e-90,
Organism=Caenorhabditis elegans, GI133931226, Length=492, Percent_Identity=32.1138211382114, Blast_Score=225, Evalue=1e-58,
Organism=Caenorhabditis elegans, GI71997168, Length=516, Percent_Identity=30.0387596899225, Blast_Score=222, Evalue=9e-58,
Organism=Caenorhabditis elegans, GI71997163, Length=510, Percent_Identity=30, Blast_Score=222, Evalue=1e-57,
Organism=Saccharomyces cerevisiae, GI6319695, Length=1162, Percent_Identity=45.2667814113597, Blast_Score=1033, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6321376, Length=1158, Percent_Identity=45.6822107081174, Blast_Score=1029, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319685, Length=455, Percent_Identity=39.5604395604396, Blast_Score=319, Evalue=1e-87,
Organism=Saccharomyces cerevisiae, GI6324343, Length=512, Percent_Identity=31.4453125, Blast_Score=239, Evalue=2e-63,
Organism=Saccharomyces cerevisiae, GI6323863, Length=437, Percent_Identity=34.7826086956522, Blast_Score=239, Evalue=2e-63,
Organism=Drosophila melanogaster, GI24652212, Length=1151, Percent_Identity=46.133796698523, Blast_Score=1062, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652210, Length=1151, Percent_Identity=46.133796698523, Blast_Score=1062, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652214, Length=1151, Percent_Identity=46.133796698523, Blast_Score=1062, Evalue=0.0,
Organism=Drosophila melanogaster, GI19921944, Length=1151, Percent_Identity=46.133796698523, Blast_Score=1062, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652216, Length=1151, Percent_Identity=46.133796698523, Blast_Score=1062, Evalue=0.0,
Organism=Drosophila melanogaster, GI281363050, Length=1166, Percent_Identity=45.6260720411664, Blast_Score=1054, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652224, Length=1166, Percent_Identity=45.6260720411664, Blast_Score=1054, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652222, Length=1166, Percent_Identity=45.6260720411664, Blast_Score=1054, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652220, Length=1166, Percent_Identity=45.6260720411664, Blast_Score=1054, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652218, Length=1166, Percent_Identity=45.6260720411664, Blast_Score=1054, Evalue=0.0,
Organism=Drosophila melanogaster, GI24651757, Length=458, Percent_Identity=42.3580786026201, Blast_Score=379, Evalue=1e-105,
Organism=Drosophila melanogaster, GI24651759, Length=415, Percent_Identity=42.1686746987952, Blast_Score=337, Evalue=2e-92,
Organism=Drosophila melanogaster, GI161076407, Length=509, Percent_Identity=29.4695481335953, Blast_Score=236, Evalue=8e-62,
Organism=Drosophila melanogaster, GI24586460, Length=509, Percent_Identity=29.4695481335953, Blast_Score=236, Evalue=8e-62,
Organism=Drosophila melanogaster, GI161076409, Length=509, Percent_Identity=29.4695481335953, Blast_Score=236, Evalue=8e-62,
Organism=Drosophila melanogaster, GI24586458, Length=509, Percent_Identity=29.4695481335953, Blast_Score=236, Evalue=9e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011761
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR011764
- InterPro:   IPR005482
- InterPro:   IPR000089
- InterPro:   IPR005479
- InterPro:   IPR005481
- InterPro:   IPR003379
- InterPro:   IPR013817
- InterPro:   IPR016185
- InterPro:   IPR000891
- InterPro:   IPR005930
- InterPro:   IPR011054
- InterPro:   IPR011053 [H]

Pfam domain/function: PF02785 Biotin_carb_C; PF00364 Biotin_lipoyl; PF00289 CPSase_L_chain; PF02786 CPSase_L_D2; PF00682 HMGL-like; PF02436 PYC_OADA [H]

EC number: =6.4.1.1 [H]

Molecular weight: Translated: 128342; Mature: 128342

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS50975 ATP_GRASP ; PS00867 CPSASE_2 ; PS50979 BC ; PS50991 PYR_CT ; PS50968 BIOTINYL_LIPOYL ; PS00188 BIOTIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKIKKLLVANRGEIAIRIFRACSELGIRSVAIYSEEDKTSLFRTKADESYLIKDAASPL
CCHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEEECCCCHHHHHHCCCCCCHHHHHHHHHH
SSYLDIEKIIAIAKSKHCDAIHPGYGFLSENAEFARRCRENGIIFVGPDESVLHSLGDKV
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCEEEECCCHHHHHHHHHHH
QSKLVAKKAGVQTIEGVETPIRNKNEALEIANQIGYPVMVKACAGGGGRGMRIVEKESDL
HHHHHHHHCCCHHHHHCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCEEEEHHHHH
MSSFVSAQNESKKAFGSDDMFIEKYIRNPKHIEVQIIADNHGNILHLYERDCSIQRRHQK
HHHHHHHCCCCHHCCCCCHHHHHHHHCCCCEEEEEEEECCCCCEEEEECCCCHHHHHHHH
VVEFAPAFSISEKTKNELHNDAIKICKEVGYTNAGTVEFLVDEDENHYFIEVNPRVQVEH
HHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEEECCCEEEHH
TVSELITGIDIVQTQILIADGKSFDSDEIGIYSQDDIHTNGYAIQCRITTEDPANNFMPD
HHHHHHHHHHHHEEEEEEECCCCCCCCCCCEEECCCCCCCCEEEEEEEECCCCCCCCCCC
TGKIDLYRTSSGFGVRLDGGNGFTGSVITPYYDSLLVKITAFSRTFNDTINKAIRALRET
CCCEEEEEECCCCEEEECCCCCCCCCCCCHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHH
KISGVKTNIGFIINVLNTEEFHKGTCDTGFISKNPELFDIKPSTDKELKVLNFISERSIN
HHCCCEECCEEEEEEECCHHHCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHCCC
NDKKDYNIPQIPEFTKTNSTGTKDIFEEKGAKGLSDWILNQDKLLITDTTLRDAHQSLMA
CCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCHHHHCCCCCEEEEECHHHHHHHHHHH
TRMRTRDMLPIAEATNELMKDLFSLEMWGGATFDVSYRFLKEDPWIRLQELRKRIPNILF
HHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCHHHHHHHHHHHHHH
QMLLRGNNTVGYKNYPDNVVVKFVQKAAENGIDVFRVFDSLNYIDGMRLACDSVLEQGKI
HHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCHHCCHHHHHHHHHHCCCE
LEATLCYTGDILDETRDKYSLEYYVKKAKELESIGANIIAIKDMSALLKPYAATKLISAL
EEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHH
KNEISVPIHLHTHDTTGNGVATIINACESGVDIVDTCFNSMSSLTSQPALNSVVAALENT
HHCCCCEEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCC
PRQTGISLSNCDKISNYYKDVRSYYSQFESDLKSGTTEIYRYEIPGGQYSNLKPQVESFG
CHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCHHHCC
LGEKFDEVKLMYKKVNDMLGDIIKVTPSSKMVGDMAIFMVANGLTPENIYEKGKNLDYPD
CCCHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHEEEEEEECCCCHHHHHHCCCCCCCCH
SVISFFKGMMGQPERGFNEKLQKIVLKDEKPITKRAGLYIDPFDFEKDKKDLEDKYKMEF
HHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCHHHCCCEECCCCCCCCHHHHHHHHHCCC
DEKDIISHALYPKVFEEYIDYRKTKGNFTYMDTPTFFEGINEKETVEVPIEEGKILIIKL
CHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHCCCCCCEEEEECCCCCEEEEEE
IEKGRLEKDGYRNFTYEVNGNRREVKVFDESAKITEREEDNLSVADPNNDKEIGASIPGR
ECCCCCCCCCCCCEEEEECCCEEEEEEECCCCCCCCCCCCCEEECCCCCCCCCCCCCCHH
VVKVLVKENDKVSVNDPLVVVEAMKMETNILSKSEGIVKSILIKENDTIDTDQLLIVLE
HHHHEECCCCEEECCCCEEEEEHHHHHHHHHHCCCCHHHHHEECCCCCCCCCCEEEEEC
>Mature Secondary Structure
MDKIKKLLVANRGEIAIRIFRACSELGIRSVAIYSEEDKTSLFRTKADESYLIKDAASPL
CCHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEEECCCCHHHHHHCCCCCCHHHHHHHHHH
SSYLDIEKIIAIAKSKHCDAIHPGYGFLSENAEFARRCRENGIIFVGPDESVLHSLGDKV
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCEEEECCCHHHHHHHHHHH
QSKLVAKKAGVQTIEGVETPIRNKNEALEIANQIGYPVMVKACAGGGGRGMRIVEKESDL
HHHHHHHHCCCHHHHHCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCEEEEHHHHH
MSSFVSAQNESKKAFGSDDMFIEKYIRNPKHIEVQIIADNHGNILHLYERDCSIQRRHQK
HHHHHHHCCCCHHCCCCCHHHHHHHHCCCCEEEEEEEECCCCCEEEEECCCCHHHHHHHH
VVEFAPAFSISEKTKNELHNDAIKICKEVGYTNAGTVEFLVDEDENHYFIEVNPRVQVEH
HHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEEECCCEEEHH
TVSELITGIDIVQTQILIADGKSFDSDEIGIYSQDDIHTNGYAIQCRITTEDPANNFMPD
HHHHHHHHHHHHEEEEEEECCCCCCCCCCCEEECCCCCCCCEEEEEEEECCCCCCCCCCC
TGKIDLYRTSSGFGVRLDGGNGFTGSVITPYYDSLLVKITAFSRTFNDTINKAIRALRET
CCCEEEEEECCCCEEEECCCCCCCCCCCCHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHH
KISGVKTNIGFIINVLNTEEFHKGTCDTGFISKNPELFDIKPSTDKELKVLNFISERSIN
HHCCCEECCEEEEEEECCHHHCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHCCC
NDKKDYNIPQIPEFTKTNSTGTKDIFEEKGAKGLSDWILNQDKLLITDTTLRDAHQSLMA
CCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCHHHHCCCCCEEEEECHHHHHHHHHHH
TRMRTRDMLPIAEATNELMKDLFSLEMWGGATFDVSYRFLKEDPWIRLQELRKRIPNILF
HHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCHHHHHHHHHHHHHH
QMLLRGNNTVGYKNYPDNVVVKFVQKAAENGIDVFRVFDSLNYIDGMRLACDSVLEQGKI
HHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCHHCCHHHHHHHHHHCCCE
LEATLCYTGDILDETRDKYSLEYYVKKAKELESIGANIIAIKDMSALLKPYAATKLISAL
EEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHH
KNEISVPIHLHTHDTTGNGVATIINACESGVDIVDTCFNSMSSLTSQPALNSVVAALENT
HHCCCCEEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCC
PRQTGISLSNCDKISNYYKDVRSYYSQFESDLKSGTTEIYRYEIPGGQYSNLKPQVESFG
CHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCHHHCC
LGEKFDEVKLMYKKVNDMLGDIIKVTPSSKMVGDMAIFMVANGLTPENIYEKGKNLDYPD
CCCHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHEEEEEEECCCCHHHHHHCCCCCCCCH
SVISFFKGMMGQPERGFNEKLQKIVLKDEKPITKRAGLYIDPFDFEKDKKDLEDKYKMEF
HHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCHHHCCCEECCCCCCCCHHHHHHHHHCCC
DEKDIISHALYPKVFEEYIDYRKTKGNFTYMDTPTFFEGINEKETVEVPIEEGKILIIKL
CHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHCCCCCCEEEEECCCCCEEEEEE
IEKGRLEKDGYRNFTYEVNGNRREVKVFDESAKITEREEDNLSVADPNNDKEIGASIPGR
ECCCCCCCCCCCCEEEEECCCEEEEEEECCCCCCCCCCCCCEEECCCCCCCCCCCCCCHH
VVKVLVKENDKVSVNDPLVVVEAMKMETNILSKSEGIVKSILIKENDTIDTDQLLIVLE
HHHHEECCCCEEECCCCEEEEEHHHHHHHHHHCCCCHHHHHEECCCCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]