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The map label for this gene is comEB [H]

Identifier: 169825268

GI number: 169825268

Start: 1742321

End: 1742740

Strand: Direct

Name: comEB [H]

Synonym: FMG_1571

Alternate gene names: 169825268

Gene position: 1742321-1742740 (Clockwise)

Preceding gene: 169825267

Following gene: 169825269

Centisome position: 96.93

GC content: 38.57

Gene sequence:

>420_bases
ATGAGAAAATCTTGGAATGAATATTTTATGGATTTGGCATTGAATGTTGCGACACGAAGCACTTGTGACAGGGCATTTGT
CGGTTGTGTGTTGGTGAATTCTGACAACAGGATTGTATCGACAGGTTACAATGGTGCTATTAGTGGCAATCCTCACTGCG
ACGAGGTTGGTCACACTTTGCGTGACGGACATTGTATTGCTACGATTCACGCAGAGATGAATGCTTTGTTGTATTGTGCG
AAAGAAGGAATTGCTGTGAAGGGTTGTATTTGTTATGTGACTCATTTTCCTTGTTTGAACTGCACGAAATCTTTAATTCA
AGCTGGAATTAGCAAGATTTATTATCACGAGGCTTATCGTGTAGATGATTATGCGATTGAATTGTTAGACCGAAATAATA
TTGAATATGTCCAAATTTAA

Upstream 100 bases:

>100_bases
TTTTTTGTGTGTGATTTTCCCTGTGTTTCTGTTTAGATTTTTGTGCTTTTATGATAATATTAAAGGTAAAGAAATTTTTT
AATGATGATGAGAGGTCAGT

Downstream 100 bases:

>100_bases
AGAGGTGTAATATGGATAAAATAAAAAAACTTCTTGTGGCAAACCGTGGCGAAATTGCTATAAGAATTTTCAGAGCTTGT
AGTGAGCTTGGAATAAGAAG

Product: putative late competence protein required for DNA binding

Products: dUMP; NH3

Alternate protein names: NA

Number of amino acids: Translated: 139; Mature: 139

Protein sequence:

>139_residues
MRKSWNEYFMDLALNVATRSTCDRAFVGCVLVNSDNRIVSTGYNGAISGNPHCDEVGHTLRDGHCIATIHAEMNALLYCA
KEGIAVKGCICYVTHFPCLNCTKSLIQAGISKIYYHEAYRVDDYAIELLDRNNIEYVQI

Sequences:

>Translated_139_residues
MRKSWNEYFMDLALNVATRSTCDRAFVGCVLVNSDNRIVSTGYNGAISGNPHCDEVGHTLRDGHCIATIHAEMNALLYCA
KEGIAVKGCICYVTHFPCLNCTKSLIQAGISKIYYHEAYRVDDYAIELLDRNNIEYVQI
>Mature_139_residues
MRKSWNEYFMDLALNVATRSTCDRAFVGCVLVNSDNRIVSTGYNGAISGNPHCDEVGHTLRDGHCIATIHAEMNALLYCA
KEGIAVKGCICYVTHFPCLNCTKSLIQAGISKIYYHEAYRVDDYAIELLDRNNIEYVQI

Specific function: Dispensable for transformability [H]

COG id: COG2131

COG function: function code F; Deoxycytidylate deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI61742819, Length=128, Percent_Identity=40.625, Blast_Score=77, Evalue=6e-15,
Organism=Homo sapiens, GI61742821, Length=128, Percent_Identity=40.625, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17557019, Length=142, Percent_Identity=35.2112676056338, Blast_Score=71, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6321938, Length=147, Percent_Identity=36.0544217687075, Blast_Score=91, Evalue=6e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR013404
- InterPro:   IPR015517
- InterPro:   IPR016193
- InterPro:   IPR016473 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: 3.5.4.12

Molecular weight: Translated: 15574; Mature: 15574

Theoretical pI: Translated: 6.49; Mature: 6.49

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

6.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
8.6 %Cys+Met (Translated Protein)
6.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
8.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKSWNEYFMDLALNVATRSTCDRAFVGCVLVNSDNRIVSTGYNGAISGNPHCDEVGHTL
CCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEECCCCCCCCCCCCHHHHCCHH
RDGHCIATIHAEMNALLYCAKEGIAVKGCICYVTHFPCLNCTKSLIQAGISKIYYHEAYR
CCCCEEEEEEHHHHEEEEECCCCCEEEHEEEEEECCCHHHHHHHHHHHHHHHHHHHHCEE
VDDYAIELLDRNNIEYVQI
CCHHEEEEECCCCEEEEEC
>Mature Secondary Structure
MRKSWNEYFMDLALNVATRSTCDRAFVGCVLVNSDNRIVSTGYNGAISGNPHCDEVGHTL
CCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEECCCCCCCCCCCCHHHHCCHH
RDGHCIATIHAEMNALLYCAKEGIAVKGCICYVTHFPCLNCTKSLIQAGISKIYYHEAYR
CCCCEEEEEEHHHHEEEEECCCCCEEEHEEEEEECCCHHHHHHHHHHHHHHHHHHHHCEE
VDDYAIELLDRNNIEYVQI
CCHHEEEEECCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: dCMP; H2O

Specific reaction: dCMP + H2O = dUMP + NH3

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7968523; 8969508; 9384377 [H]