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The map label for this gene is pepD [H]

Identifier: 169825159

GI number: 169825159

Start: 1615681

End: 1617120

Strand: Direct

Name: pepD [H]

Synonym: FMG_1462

Alternate gene names: 169825159

Gene position: 1615681-1617120 (Clockwise)

Preceding gene: 169825158

Following gene: 169825161

Centisome position: 89.88

GC content: 36.04

Gene sequence:

>1440_bases
ATGCAAAGATATGAAGATTTAGAACCAAAGAATGTGTTTCATTGGTTCAAACAATTAAACGATATTCCTCGTGGTTCAGG
AAATGAAAAAGGCGTTTCAGATTTTTTGGTTAGTTTTGCAAAGGAAAGAGGATTGGAAGTATACCAAGATCATCTTAACA
ATGTAATTATCAAAAAAGAAGCTACAAAAGGTTACGAAAATTCAGAGCCAGTTATTTTGCAAGGACACATGGACATGGTT
TGCGAAAAGACTGATGATTCAGACCACGATTTCTTAAAAGATCCTATCTCAATGCACGTTAAGGACGGATATGTTTATGC
AGATAACACAACTTTGGGAGCAGATGACGGAATCGCTGTTGCGTTTTGCTTAGCTATTTTGGATTCTGATAATGTTTCTC
ATCCAAAATTGGAAGTTCTTGTAACAATTGATGAAGAACGTGGAATGGACGGAGCAAACGGTGTGACTGCTGAACATTTG
AGTGGAACTCGTTTGTTAAACATTGACACTGAAACCGAAGGAGAATTCATTGTAAGCTGTTCTGGTGGAGCAAATGCTAT
CACTACTTTCAAGAGCGAAAAATCAGAAGGTTTGTCAAAAGCTATTGAAATTTCTCTTTCTGGTTTGAATGGTGGTCACT
CTGGTCTTGAAATTCAAAAACAAAACAAAAATGCCATCAAAGTTATGGCAAGACTTTTGAACAAAGTTGCTTTGGAAATG
GATTTTAGATTGCAAGAAATCTCCGGTGGATCAAAACACAATGCCATCGCAAAGAATGCTCACGCTATCATCACTGTTGA
TGATTTGGACAAAGCAATGAATATTTTAAACGAAATTGGAGAATACGTTCGTCACGAAGGTAGAAAAACAGATCCTAACT
TGGTTTTGGATATTAAAGAAACAGAAAAAACAGAATTTTCTTATTCAAAAGAAACTTCTCAATCTATCGTTAAATTCTTG
TATTTGTTAATCAACGATGTTATTTCAACTTCACAAGACATCGAAGGTTTGGTTCAAACAAGTTCAAACGTTGGTGTTGT
TGAAGCAGACGACGAACAAATCAAGGTTACTTGTTGTGTAAGAAGTTCTGTAGAAAGCGAACTTCACAATATGTTCGACA
AGATCAAATCATTAGCTTATTTGACTCACGGAACTACTGTTATCGAAAAAGAATATCCAGCATGGGAATTCAACACTGAT
GGAGAATTGGCAAAGGTTGCTCCAGCATTGTACGAAGAAATGACTGGCAAGAAAGCTAATGTAACTGCAATCCACGCAGG
TTTGGAATGTGGTTTGTTGAAAGGCGTTCTTCCTGATTGCGATATGATTAGTTTCGGTCCAGATATTTTCGGAGCTCACA
CTCCATTGGAACATTTGGGAATTGAATCTACTCAAAGAATGTACGATTACACATTAAAATTATTAGAAAAATTAAAATAA

Upstream 100 bases:

>100_bases
ATGGATATTATCGTAAATGTTGTAAATAATCTTGTCAATTAGATTACAAAATATTGTAAAAGAGTTATAATAAAGGAAGA
ATATAAATAGGAGGTTACTC

Downstream 100 bases:

>100_bases
CAAAAAATTAAGGAAAGTTCTTTTTATGAACTTTCCTTTTTGAATTATTTGTATTCGTGATTTTCTAAAACATGGATTAA
ATCTTCATTAGTTTCTTTAC

Product: aminoacyl-histidine dipeptidase

Products: NA

Alternate protein names: Beta-alanyl-histidine dipeptidase; Carnosinase; Peptidase D; Xaa-His dipeptidase; X-His dipeptidase [H]

Number of amino acids: Translated: 479; Mature: 479

Protein sequence:

>479_residues
MQRYEDLEPKNVFHWFKQLNDIPRGSGNEKGVSDFLVSFAKERGLEVYQDHLNNVIIKKEATKGYENSEPVILQGHMDMV
CEKTDDSDHDFLKDPISMHVKDGYVYADNTTLGADDGIAVAFCLAILDSDNVSHPKLEVLVTIDEERGMDGANGVTAEHL
SGTRLLNIDTETEGEFIVSCSGGANAITTFKSEKSEGLSKAIEISLSGLNGGHSGLEIQKQNKNAIKVMARLLNKVALEM
DFRLQEISGGSKHNAIAKNAHAIITVDDLDKAMNILNEIGEYVRHEGRKTDPNLVLDIKETEKTEFSYSKETSQSIVKFL
YLLINDVISTSQDIEGLVQTSSNVGVVEADDEQIKVTCCVRSSVESELHNMFDKIKSLAYLTHGTTVIEKEYPAWEFNTD
GELAKVAPALYEEMTGKKANVTAIHAGLECGLLKGVLPDCDMISFGPDIFGAHTPLEHLGIESTQRMYDYTLKLLEKLK

Sequences:

>Translated_479_residues
MQRYEDLEPKNVFHWFKQLNDIPRGSGNEKGVSDFLVSFAKERGLEVYQDHLNNVIIKKEATKGYENSEPVILQGHMDMV
CEKTDDSDHDFLKDPISMHVKDGYVYADNTTLGADDGIAVAFCLAILDSDNVSHPKLEVLVTIDEERGMDGANGVTAEHL
SGTRLLNIDTETEGEFIVSCSGGANAITTFKSEKSEGLSKAIEISLSGLNGGHSGLEIQKQNKNAIKVMARLLNKVALEM
DFRLQEISGGSKHNAIAKNAHAIITVDDLDKAMNILNEIGEYVRHEGRKTDPNLVLDIKETEKTEFSYSKETSQSIVKFL
YLLINDVISTSQDIEGLVQTSSNVGVVEADDEQIKVTCCVRSSVESELHNMFDKIKSLAYLTHGTTVIEKEYPAWEFNTD
GELAKVAPALYEEMTGKKANVTAIHAGLECGLLKGVLPDCDMISFGPDIFGAHTPLEHLGIESTQRMYDYTLKLLEKLK
>Mature_479_residues
MQRYEDLEPKNVFHWFKQLNDIPRGSGNEKGVSDFLVSFAKERGLEVYQDHLNNVIIKKEATKGYENSEPVILQGHMDMV
CEKTDDSDHDFLKDPISMHVKDGYVYADNTTLGADDGIAVAFCLAILDSDNVSHPKLEVLVTIDEERGMDGANGVTAEHL
SGTRLLNIDTETEGEFIVSCSGGANAITTFKSEKSEGLSKAIEISLSGLNGGHSGLEIQKQNKNAIKVMARLLNKVALEM
DFRLQEISGGSKHNAIAKNAHAIITVDDLDKAMNILNEIGEYVRHEGRKTDPNLVLDIKETEKTEFSYSKETSQSIVKFL
YLLINDVISTSQDIEGLVQTSSNVGVVEADDEQIKVTCCVRSSVESELHNMFDKIKSLAYLTHGTTVIEKEYPAWEFNTD
GELAKVAPALYEEMTGKKANVTAIHAGLECGLLKGVLPDCDMISFGPDIFGAHTPLEHLGIESTQRMYDYTLKLLEKLK

Specific function: Dipeptidase with broad substrate specificity [H]

COG id: COG2195

COG function: function code E; Di- and tripeptidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20C family [H]

Homologues:

Organism=Escherichia coli, GI1786432, Length=483, Percent_Identity=36.231884057971, Blast_Score=318, Evalue=4e-88,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002933
- InterPro:   IPR011650
- InterPro:   IPR001160 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.4.13.3 [H]

Molecular weight: Translated: 52940; Mature: 52940

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRYEDLEPKNVFHWFKQLNDIPRGSGNEKGVSDFLVSFAKERGLEVYQDHLNNVIIKKE
CCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHCCEEEEEC
ATKGYENSEPVILQGHMDMVCEKTDDSDHDFLKDPISMHVKDGYVYADNTTLGADDGIAV
CCCCCCCCCCEEEECCHHHEEECCCCCCHHHHCCCHHEEEECCEEEECCCCCCCCCCHHH
AFCLAILDSDNVSHPKLEVLVTIDEERGMDGANGVTAEHLSGTRLLNIDTETEGEFIVSC
HHHHHHHCCCCCCCCEEEEEEEEEHHCCCCCCCCCCHHHCCCCEEEEECCCCCCCEEEEE
SGGANAITTFKSEKSEGLSKAIEISLSGLNGGHSGLEIQKQNKNAIKVMARLLNKVALEM
CCCCCEEEEECCHHHHHHHHEEEEEEECCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHH
DFRLQEISGGSKHNAIAKNAHAIITVDDLDKAMNILNEIGEYVRHEGRKTDPNLVLDIKE
CCCHHCCCCCCCCCHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEC
TEKTEFSYSKETSQSIVKFLYLLINDVISTSQDIEGLVQTSSNVGVVEADDEQIKVTCCV
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCEEECCCCEEEEEEEE
RSSVESELHNMFDKIKSLAYLTHGTTVIEKEYPAWEFNTDGELAKVAPALYEEMTGKKAN
HHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEECCCCCCHHHHHHHHHHHHCCCCCC
VTAIHAGLECGLLKGVLPDCDMISFGPDIFGAHTPLEHLGIESTQRMYDYTLKLLEKLK
EEEEECCCHHHHHHCCCCCCCEEECCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQRYEDLEPKNVFHWFKQLNDIPRGSGNEKGVSDFLVSFAKERGLEVYQDHLNNVIIKKE
CCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHCCEEEEEC
ATKGYENSEPVILQGHMDMVCEKTDDSDHDFLKDPISMHVKDGYVYADNTTLGADDGIAV
CCCCCCCCCCEEEECCHHHEEECCCCCCHHHHCCCHHEEEECCEEEECCCCCCCCCCHHH
AFCLAILDSDNVSHPKLEVLVTIDEERGMDGANGVTAEHLSGTRLLNIDTETEGEFIVSC
HHHHHHHCCCCCCCCEEEEEEEEEHHCCCCCCCCCCHHHCCCCEEEEECCCCCCCEEEEE
SGGANAITTFKSEKSEGLSKAIEISLSGLNGGHSGLEIQKQNKNAIKVMARLLNKVALEM
CCCCCEEEEECCHHHHHHHHEEEEEEECCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHH
DFRLQEISGGSKHNAIAKNAHAIITVDDLDKAMNILNEIGEYVRHEGRKTDPNLVLDIKE
CCCHHCCCCCCCCCHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEC
TEKTEFSYSKETSQSIVKFLYLLINDVISTSQDIEGLVQTSSNVGVVEADDEQIKVTCCV
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCEEECCCCEEEEEEEE
RSSVESELHNMFDKIKSLAYLTHGTTVIEKEYPAWEFNTDGELAKVAPALYEEMTGKKAN
HHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEECCCCCCHHHHHHHHHHHHCCCCCC
VTAIHAGLECGLLKGVLPDCDMISFGPDIFGAHTPLEHLGIESTQRMYDYTLKLLEKLK
EEEEECCCHHHHHHCCCCCCCEEECCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]