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The map label for this gene is ppnK

Identifier: 169824724

GI number: 169824724

Start: 1113588

End: 1114409

Strand: Direct

Name: ppnK

Synonym: FMG_1027

Alternate gene names: 169824724

Gene position: 1113588-1114409 (Clockwise)

Preceding gene: 169824711

Following gene: 169824741

Centisome position: 61.95

GC content: 31.63

Gene sequence:

>822_bases
ATGAACAATAACAGCAAAATTATAAATATATATGTAAACGATAACCAAAAATCGCTGGAAACAGCGCTGATTGTCAAAGA
TAAATTAGAACAGAAAGGATTCAAACCTACATTTGATTTTGACGAAAATGCACTAATTAATCTATGCATTGGCGGGGATG
GTGCTTTTTTAAGAGCTGTTCATAAATACGAGTTTTCAACAATTCCTTTCGTTGGAATAAATACAGGACATCTTGGATTT
TATCAAGAAATTTTAATTCCAAATATCGACAAATTTATTTCAGATTTAATCAATGAAAATTATGGAATTGAAAAAATTTC
TTTACTAGAATCAAAAACCGCAATCAGAAATAGCAGCAAAACTTATACACACAAAGCACTTAACGAGTTCGTAGTAAAAA
GCGATGACTCCTCTATTGTATATTTGGATGTATACATCGATGATAATCACTTAGAATCATTTGCTGGAGATGGAATAATA
GTCTCCACTCCTTCTGGGTCAACTGCATATAACTTCTCAGCGGGTGGATCTGTTTTGTATCATGGTCTAGATGGTTTCCA
AGTGACTCCACTAGCTCCAATTAATTCGAAAGCTTATCGTTCACTTTTGAATTCTCTTGTAGTTCCATCGAAAAGTAATG
TTACATTGTATTTTAGAGACCACAATTTTGACAGAAAAAGTTCCATAGTTTTGGCAGACGGATTGAACAGAAGCTATGAT
AATGTAGATTATGTAAATTTCACTTATTCTGATCAATATATCAACAAATTAGTTTTCTTAAAAGACTGGTATTGGTTAAA
TATCAAAGACAAATTCTTATAA

Upstream 100 bases:

>100_bases
TATTTTTTTATCTACATTAAAACTAATTTGTCTCATTGTTTAAATCTCCAGTTATTTGGTATAATAAAATTATAACAAAT
ATTAGGAGCTTTTAGAATAA

Downstream 100 bases:

>100_bases
AAAGAAAAACATGGATTGCAATGAATTATCAAAGCTATCCATGTTTTTTTATTTTTCTAAACCCAATTCATTAATTGCTG
CGTTAAGCATTTTTGAAGCT

Product: inorganic polyphosphate/ATP-NAD kinase

Products: NA

Alternate protein names: Poly(P)/ATP NAD kinase

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MNNNSKIINIYVNDNQKSLETALIVKDKLEQKGFKPTFDFDENALINLCIGGDGAFLRAVHKYEFSTIPFVGINTGHLGF
YQEILIPNIDKFISDLINENYGIEKISLLESKTAIRNSSKTYTHKALNEFVVKSDDSSIVYLDVYIDDNHLESFAGDGII
VSTPSGSTAYNFSAGGSVLYHGLDGFQVTPLAPINSKAYRSLLNSLVVPSKSNVTLYFRDHNFDRKSSIVLADGLNRSYD
NVDYVNFTYSDQYINKLVFLKDWYWLNIKDKFL

Sequences:

>Translated_273_residues
MNNNSKIINIYVNDNQKSLETALIVKDKLEQKGFKPTFDFDENALINLCIGGDGAFLRAVHKYEFSTIPFVGINTGHLGF
YQEILIPNIDKFISDLINENYGIEKISLLESKTAIRNSSKTYTHKALNEFVVKSDDSSIVYLDVYIDDNHLESFAGDGII
VSTPSGSTAYNFSAGGSVLYHGLDGFQVTPLAPINSKAYRSLLNSLVVPSKSNVTLYFRDHNFDRKSSIVLADGLNRSYD
NVDYVNFTYSDQYINKLVFLKDWYWLNIKDKFL
>Mature_273_residues
MNNNSKIINIYVNDNQKSLETALIVKDKLEQKGFKPTFDFDENALINLCIGGDGAFLRAVHKYEFSTIPFVGINTGHLGF
YQEILIPNIDKFISDLINENYGIEKISLLESKTAIRNSSKTYTHKALNEFVVKSDDSSIVYLDVYIDDNHLESFAGDGII
VSTPSGSTAYNFSAGGSVLYHGLDGFQVTPLAPINSKAYRSLLNSLVVPSKSNVTLYFRDHNFDRKSSIVLADGLNRSYD
NVDYVNFTYSDQYINKLVFLKDWYWLNIKDKFL

Specific function: Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus

COG id: COG0061

COG function: function code G; Predicted sugar kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD kinase family

Homologues:

Organism=Homo sapiens, GI55743112, Length=294, Percent_Identity=26.8707482993197, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1788968, Length=170, Percent_Identity=34.7058823529412, Blast_Score=93, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6320794, Length=221, Percent_Identity=27.6018099547511, Blast_Score=77, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6325068, Length=172, Percent_Identity=27.906976744186, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PPNK_FINM2 (B0S255)

Other databases:

- EMBL:   AP008971
- RefSeq:   YP_001692335.1
- ProteinModelPortal:   B0S255
- SMR:   B0S255
- GeneID:   6018919
- GenomeReviews:   AP008971_GR
- KEGG:   fma:FMG_1027
- HOGENOM:   HBG304920
- OMA:   KITENDP
- ProtClustDB:   CLSK965924
- BioCyc:   FMAG334413:FMG_1027-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00361
- InterPro:   IPR016064
- InterPro:   IPR017438
- InterPro:   IPR017437
- InterPro:   IPR002504
- Gene3D:   G3DSA:2.60.200.30
- Gene3D:   G3DSA:3.40.50.10330
- PANTHER:   PTHR20275

Pfam domain/function: PF01513 NAD_kinase; SSF111331 ATP-NAD_kinase_PpnK-typ

EC number: =2.7.1.23

Molecular weight: Translated: 30856; Mature: 30856

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNNSKIINIYVNDNQKSLETALIVKDKLEQKGFKPTFDFDENALINLCIGGDGAFLRAV
CCCCCEEEEEEECCCCHHHHEEEEEHHHHHHCCCCCCCCCCCCCEEEEEECCCCHHHHHH
HKYEFSTIPFVGINTGHLGFYQEILIPNIDKFISDLINENYGIEKISLLESKTAIRNSSK
HHCCCCCCCEEECCCCCCCHHHHHHCCCHHHHHHHHHCCCCCCCEEEHHHHHHHHCCCCC
TYTHKALNEFVVKSDDSSIVYLDVYIDDNHLESFAGDGIIVSTPSGSTAYNFSAGGSVLY
HHHHHHHHHHEEECCCCCEEEEEEEECCCHHHHHCCCCEEEECCCCCEEEEECCCCEEEE
HGLDGFQVTPLAPINSKAYRSLLNSLVVPSKSNVTLYFRDHNFDRKSSIVLADGLNRSYD
ECCCCEEEEECCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCEEEECCCCCCCC
NVDYVNFTYSDQYINKLVFLKDWYWLNIKDKFL
CCEEEEEEECHHHHCEEEEEEEEEEEEEECCCC
>Mature Secondary Structure
MNNNSKIINIYVNDNQKSLETALIVKDKLEQKGFKPTFDFDENALINLCIGGDGAFLRAV
CCCCCEEEEEEECCCCHHHHEEEEEHHHHHHCCCCCCCCCCCCCEEEEEECCCCHHHHHH
HKYEFSTIPFVGINTGHLGFYQEILIPNIDKFISDLINENYGIEKISLLESKTAIRNSSK
HHCCCCCCCEEECCCCCCCHHHHHHCCCHHHHHHHHHCCCCCCCEEEHHHHHHHHCCCCC
TYTHKALNEFVVKSDDSSIVYLDVYIDDNHLESFAGDGIIVSTPSGSTAYNFSAGGSVLY
HHHHHHHHHHEEECCCCCEEEEEEEECCCHHHHHCCCCEEEECCCCCEEEEECCCCEEEE
HGLDGFQVTPLAPINSKAYRSLLNSLVVPSKSNVTLYFRDHNFDRKSSIVLADGLNRSYD
ECCCCEEEEECCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCEEEECCCCCCCC
NVDYVNFTYSDQYINKLVFLKDWYWLNIKDKFL
CCEEEEEEECHHHHCEEEEEEEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA