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The map label for this gene is yycF [H]

Identifier: 169824410

GI number: 169824410

Start: 777457

End: 778155

Strand: Direct

Name: yycF [H]

Synonym: FMG_0713

Alternate gene names: 169824410

Gene position: 777457-778155 (Clockwise)

Preceding gene: 169824409

Following gene: 169824411

Centisome position: 43.25

GC content: 29.9

Gene sequence:

>699_bases
ATGAAACTTAGAATTCTATTAGTTTTTCCTTCAAGCGTCTATAAAGATGAGATTATTCTTAATTTTTCAAATGATGAAAA
TTATGAAGTATCTGAATGTTCAACAATTCAAGACGCACTTGAAAAACTAAAAAAAGGTTACTACGATTTTTTGCTGTGTG
ATATGAATTTTTCGGATGGGACAGGTTTAGATTTCAAAAAGGAAATTAGTAAATTATATTCTATTCCTACAATTTTTGTT
AGTGATGAATCCGATGATATGAAAAAAATTTTGGCTCTTGAATATGGAGCGGATGATTATGTAGTTTATCCATTTAATAT
GCTGGAGCTTAAGGCTAGAATTAGAGCTGTTCTTAGAAGAACAAAATCAGATTTTGATAGTGAAAACAAAAATTCAAATA
TAATGCAAATAGGTGGATTCGAGTTCAATCTGATATCACGAAGTGTAAAGAGATATGGTCAAGATGTCGAGTTAACTGGA
AGAGAATTCGAATTACTATATGCACTTGTTTCTAATAAAGATAAAGTTCTCTCAAGGAAGGAATTAGCAGCGAAATTATG
GGAAGACGCACAATCTCATATTCGAACTGTAGATGTTCATATTAAAAGATTAAGAGAGAAAATCAAAGACAACGAATCAA
TAATAATAAGAACAAAATGGGGAGAAGGATATTACTTCTCTTCAAATACAAAACTTTAA

Upstream 100 bases:

>100_bases
AAACTTGTTAAGAAGCTTCATGAATCTGGACAAGTTGGAAATATTATCGGAAAAGTAAAAGAAAAGGCAGATCACTTTAT
AGAAGTTATCTAATTGATTT

Downstream 100 bases:

>100_bases
ACTGCTTTTATAAAGCAGTTTAATTATTTATGGAGGAAATATGTATCAAACAGATATACCTAAAAAAGATCAATTAATTG
CAAATATAACTACAAATTTA

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MKLRILLVFPSSVYKDEIILNFSNDENYEVSECSTIQDALEKLKKGYYDFLLCDMNFSDGTGLDFKKEISKLYSIPTIFV
SDESDDMKKILALEYGADDYVVYPFNMLELKARIRAVLRRTKSDFDSENKNSNIMQIGGFEFNLISRSVKRYGQDVELTG
REFELLYALVSNKDKVLSRKELAAKLWEDAQSHIRTVDVHIKRLREKIKDNESIIIRTKWGEGYYFSSNTKL

Sequences:

>Translated_232_residues
MKLRILLVFPSSVYKDEIILNFSNDENYEVSECSTIQDALEKLKKGYYDFLLCDMNFSDGTGLDFKKEISKLYSIPTIFV
SDESDDMKKILALEYGADDYVVYPFNMLELKARIRAVLRRTKSDFDSENKNSNIMQIGGFEFNLISRSVKRYGQDVELTG
REFELLYALVSNKDKVLSRKELAAKLWEDAQSHIRTVDVHIKRLREKIKDNESIIIRTKWGEGYYFSSNTKL
>Mature_232_residues
MKLRILLVFPSSVYKDEIILNFSNDENYEVSECSTIQDALEKLKKGYYDFLLCDMNFSDGTGLDFKKEISKLYSIPTIFV
SDESDDMKKILALEYGADDYVVYPFNMLELKARIRAVLRRTKSDFDSENKNSNIMQIGGFEFNLISRSVKRYGQDVELTG
REFELLYALVSNKDKVLSRKELAAKLWEDAQSHIRTVDVHIKRLREKIKDNESIIIRTKWGEGYYFSSNTKL

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF. Binds to the ftsAZ P1 promoter seque

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790860, Length=189, Percent_Identity=35.978835978836, Blast_Score=117, Evalue=5e-28,
Organism=Escherichia coli, GI1787229, Length=215, Percent_Identity=30.2325581395349, Blast_Score=109, Evalue=1e-25,
Organism=Escherichia coli, GI1789809, Length=210, Percent_Identity=30.952380952381, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1786911, Length=204, Percent_Identity=29.9019607843137, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1790552, Length=229, Percent_Identity=31.4410480349345, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1786599, Length=233, Percent_Identity=28.3261802575107, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1788394, Length=220, Percent_Identity=28.6363636363636, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI2367329, Length=172, Percent_Identity=35.4651162790698, Blast_Score=97, Evalue=6e-22,
Organism=Escherichia coli, GI1790863, Length=210, Percent_Identity=30.952380952381, Blast_Score=97, Evalue=6e-22,
Organism=Escherichia coli, GI1786784, Length=184, Percent_Identity=33.1521739130435, Blast_Score=95, Evalue=3e-21,
Organism=Escherichia coli, GI87082012, Length=233, Percent_Identity=29.1845493562232, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1787375, Length=229, Percent_Identity=27.5109170305677, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1789402, Length=227, Percent_Identity=29.0748898678414, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI145693140, Length=198, Percent_Identity=26.7676767676768, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27045; Mature: 27045

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLRILLVFPSSVYKDEIILNFSNDENYEVSECSTIQDALEKLKKGYYDFLLCDMNFSDG
CEEEEEEECCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCC
TGLDFKKEISKLYSIPTIFVSDESDDMKKILALEYGADDYVVYPFNMLELKARIRAVLRR
CCCCHHHHHHHHHCCCEEEEECCCHHHHHHHHEEECCCCEEECCHHHHHHHHHHHHHHHH
TKSDFDSENKNSNIMQIGGFEFNLISRSVKRYGQDVELTGREFELLYALVSNKDKVLSRK
HHHCCCCCCCCCCEEEECCEEHHHHHHHHHHCCCCEEECCCHHHHHHHHHCCCHHHHHHH
ELAAKLWEDAQSHIRTVDVHIKRLREKIKDNESIIIRTKWGEGYYFSSNTKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEECCCCCC
>Mature Secondary Structure
MKLRILLVFPSSVYKDEIILNFSNDENYEVSECSTIQDALEKLKKGYYDFLLCDMNFSDG
CEEEEEEECCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCC
TGLDFKKEISKLYSIPTIFVSDESDDMKKILALEYGADDYVVYPFNMLELKARIRAVLRR
CCCCHHHHHHHHHCCCEEEEECCCHHHHHHHHEEECCCCEEECCHHHHHHHHHHHHHHHH
TKSDFDSENKNSNIMQIGGFEFNLISRSVKRYGQDVELTGREFELLYALVSNKDKVLSRK
HHHCCCCCCCCCCEEEECCEEHHHHHHHHHHCCCCEEECCCHHHHHHHHHCCCHHHHHHH
ELAAKLWEDAQSHIRTVDVHIKRLREKIKDNESIIIRTKWGEGYYFSSNTKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 9829949; 10878122 [H]