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The map label for this gene is frr

Identifier: 169824406

GI number: 169824406

Start: 773101

End: 773658

Strand: Direct

Name: frr

Synonym: FMG_0709

Alternate gene names: 169824406

Gene position: 773101-773658 (Clockwise)

Preceding gene: 169824405

Following gene: 169824407

Centisome position: 43.01

GC content: 28.85

Gene sequence:

>558_bases
ATGAGTAAACAAATTTTAAAAGATATGGAAACAAAAGCTGACAAAACATTACACGCACTAAAAGAAGAGTTAAAAACAGT
AAGAGCTGGACGAGCTAATCCAAGTATATTGGATAACATTATGGTAGAATATTATGGCACTTCAACACCTTTAAAACAAG
TAGCTACTATTTCTGCACCTGAAGCTAGACTACTTACAATTCAACCATGGGATAAATCTATAATGAAAGAAATCGAAAAA
CAAATTCAAGCTTCAAATTTGGGAATTACTCCTTCTAATGATGGAACTATTATAAGATTACCATTTCCACAATTAACTGA
AGACAGAAGAAAAGAATTGACTAAGGTAGTTAAAGAATATGGTGAAAAATCAAAAGTTACTATTAGATCTATAAGAAGAG
ATTTTGTAGACGATGCAAAAAAAATGGAAAAGAATGCAGAAATTTCTGAAGATGAATTACACGTACTATTAGATGATATC
CAATCTTTAACAGATAAATTAACAAAAGAAATTGACAATATTGTTACTGATAAAGAAACAGAATTAATGGAAATTTAA

Upstream 100 bases:

>100_bases
AATAATATGGGTTTAGTGGTATTTGGAATAGATGATCCTAAAAATATAATTAGAGTTTCTCATGGAGAGAATATAGGAAC
AATTGTTGAGGGGGATAAAA

Downstream 100 bases:

>100_bases
TAAATTAATATTGATTAAAAAATCTATTCTAATGAGAATAGATTTTTTTTTGGTAAATAAATCAAATTGTAAAATCTCCA
ATTATGACAAAAATGTTACA

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor

Number of amino acids: Translated: 185; Mature: 184

Protein sequence:

>185_residues
MSKQILKDMETKADKTLHALKEELKTVRAGRANPSILDNIMVEYYGTSTPLKQVATISAPEARLLTIQPWDKSIMKEIEK
QIQASNLGITPSNDGTIIRLPFPQLTEDRRKELTKVVKEYGEKSKVTIRSIRRDFVDDAKKMEKNAEISEDELHVLLDDI
QSLTDKLTKEIDNIVTDKETELMEI

Sequences:

>Translated_185_residues
MSKQILKDMETKADKTLHALKEELKTVRAGRANPSILDNIMVEYYGTSTPLKQVATISAPEARLLTIQPWDKSIMKEIEK
QIQASNLGITPSNDGTIIRLPFPQLTEDRRKELTKVVKEYGEKSKVTIRSIRRDFVDDAKKMEKNAEISEDELHVLLDDI
QSLTDKLTKEIDNIVTDKETELMEI
>Mature_184_residues
SKQILKDMETKADKTLHALKEELKTVRAGRANPSILDNIMVEYYGTSTPLKQVATISAPEARLLTIQPWDKSIMKEIEKQ
IQASNLGITPSNDGTIIRLPFPQLTEDRRKELTKVVKEYGEKSKVTIRSIRRDFVDDAKKMEKNAEISEDELHVLLDDIQ
SLTDKLTKEIDNIVTDKETELMEI

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family

Homologues:

Organism=Homo sapiens, GI20270317, Length=180, Percent_Identity=27.2222222222222, Blast_Score=68, Evalue=4e-12,
Organism=Escherichia coli, GI1786368, Length=185, Percent_Identity=45.945945945946, Blast_Score=176, Evalue=1e-45,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): RRF_FINM2 (B0S187)

Other databases:

- EMBL:   AP008971
- RefSeq:   YP_001692017.1
- ProteinModelPortal:   B0S187
- SMR:   B0S187
- GeneID:   6019300
- GenomeReviews:   AP008971_GR
- KEGG:   fma:FMG_0709
- HOGENOM:   HBG533975
- OMA:   YYGAETP
- BioCyc:   FMAG334413:FMG_0709-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00040
- InterPro:   IPR002661
- InterPro:   IPR015998
- PANTHER:   PTHR20982
- PANTHER:   PTHR20982:SF3
- TIGRFAMs:   TIGR00496

Pfam domain/function: PF01765 RRF; SSF55194 Ribosome_recyc_fac

EC number: NA

Molecular weight: Translated: 21126; Mature: 20994

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKQILKDMETKADKTLHALKEELKTVRAGRANPSILDNIMVEYYGTSTPLKQVATISAP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHCCCC
EARLLTIQPWDKSIMKEIEKQIQASNLGITPSNDGTIIRLPFPQLTEDRRKELTKVVKEY
CCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCHHCCHHHHHHHHHHHHHH
GEKSKVTIRSIRRDFVDDAKKMEKNAEISEDELHVLLDDIQSLTDKLTKEIDNIVTDKET
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
ELMEI
HHHCC
>Mature Secondary Structure 
SKQILKDMETKADKTLHALKEELKTVRAGRANPSILDNIMVEYYGTSTPLKQVATISAP
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHCCCC
EARLLTIQPWDKSIMKEIEKQIQASNLGITPSNDGTIIRLPFPQLTEDRRKELTKVVKEY
CCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCHHCCHHHHHHHHHHHHHH
GEKSKVTIRSIRRDFVDDAKKMEKNAEISEDELHVLLDDIQSLTDKLTKEIDNIVTDKET
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
ELMEI
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA