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The map label for this gene is pyrH [H]

Identifier: 169824405

GI number: 169824405

Start: 772389

End: 773108

Strand: Direct

Name: pyrH [H]

Synonym: FMG_0708

Alternate gene names: 169824405

Gene position: 772389-773108 (Clockwise)

Preceding gene: 169824404

Following gene: 169824406

Centisome position: 42.97

GC content: 33.19

Gene sequence:

>720_bases
TTGAGTTTAAAATATAAAAGAGTTCTATTAAAATTAAGCGGTGAAGCTTTAAGTGGAGATCAAGGACATGGACTAGATGA
CGATATTATAGAAAGCATTTGTGATGCCATAAAAGTTGTTCATGATGAAGGGTTAGAAATAGCTATAGTTGTTGGTGGTG
GTAATTTCTGGCGAGGTAGATCTTCTAAAATAGATAGAGCCACATCTGATTCAATGGGAATGTTGGGTACAACTATAAAT
GCTTTAAGATTACAAGCATCATTAGAGGCAAAAGGTATTCAAACTAGGGTTCAAACTGCGATAGATATGAAACAAGTTGC
AGAACCTTATATTAGAAGAAGGGCTATAAGACATATCGAAAAAGGTAGAATTGTAATATTTGCAGCAGGAACTGGATTGC
CTTATTTTTCAACTGATACAACAGCGGCTTTACGTGCAGTAGAAATTAATGCAGATGTTATCTTAGCAGGCAAAAGAGGA
ACTGACGGTATATACGATTCTGATCCAAATAAAAACAAAAATGCCATTAAATATGATAAATTAACTTATATTGATATTTT
GAACAAAGGTTTAGGTATAATGGATGCAACTGCTACATCACTTTGCATGGAAAATAATATGGGTTTAGTGGTATTTGGAA
TAGATGATCCTAAAAATATAATTAGAGTTTCTCATGGAGAGAATATAGGAACAATTGTTGAGGGGGATAAAAATGAGTAA

Upstream 100 bases:

>100_bases
TATTGCAGCTTTTTTATTTTACATATTATCATATTGATTTTAAAATCTTAATTTGGTATGATTAATTAAAGAAAACCTTA
TTATTAATTAGGAGGAAATT

Downstream 100 bases:

>100_bases
ACAAATTTTAAAAGATATGGAAACAAAAGCTGACAAAACATTACACGCACTAAAAGAAGAGTTAAAAACAGTAAGAGCTG
GACGAGCTAATCCAAGTATA

Product: uridylate kinase

Products: NA

Alternate protein names: UK; Uridine monophosphate kinase; UMP kinase; UMPK [H]

Number of amino acids: Translated: 239; Mature: 238

Protein sequence:

>239_residues
MSLKYKRVLLKLSGEALSGDQGHGLDDDIIESICDAIKVVHDEGLEIAIVVGGGNFWRGRSSKIDRATSDSMGMLGTTIN
ALRLQASLEAKGIQTRVQTAIDMKQVAEPYIRRRAIRHIEKGRIVIFAAGTGLPYFSTDTTAALRAVEINADVILAGKRG
TDGIYDSDPNKNKNAIKYDKLTYIDILNKGLGIMDATATSLCMENNMGLVVFGIDDPKNIIRVSHGENIGTIVEGDKNE

Sequences:

>Translated_239_residues
MSLKYKRVLLKLSGEALSGDQGHGLDDDIIESICDAIKVVHDEGLEIAIVVGGGNFWRGRSSKIDRATSDSMGMLGTTIN
ALRLQASLEAKGIQTRVQTAIDMKQVAEPYIRRRAIRHIEKGRIVIFAAGTGLPYFSTDTTAALRAVEINADVILAGKRG
TDGIYDSDPNKNKNAIKYDKLTYIDILNKGLGIMDATATSLCMENNMGLVVFGIDDPKNIIRVSHGENIGTIVEGDKNE
>Mature_238_residues
SLKYKRVLLKLSGEALSGDQGHGLDDDIIESICDAIKVVHDEGLEIAIVVGGGNFWRGRSSKIDRATSDSMGMLGTTINA
LRLQASLEAKGIQTRVQTAIDMKQVAEPYIRRRAIRHIEKGRIVIFAAGTGLPYFSTDTTAALRAVEINADVILAGKRGT
DGIYDSDPNKNKNAIKYDKLTYIDILNKGLGIMDATATSLCMENNMGLVVFGIDDPKNIIRVSHGENIGTIVEGDKNE

Specific function: Catalyzes the reversible phosphorylation of UMP to UDP [H]

COG id: COG0528

COG function: function code F; Uridylate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UMP kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786367, Length=232, Percent_Identity=38.7931034482759, Blast_Score=180, Evalue=9e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001048
- InterPro:   IPR011817
- InterPro:   IPR015963 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.4.22 [H]

Molecular weight: Translated: 25921; Mature: 25790

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLKYKRVLLKLSGEALSGDQGHGLDDDIIESICDAIKVVHDEGLEIAIVVGGGNFWRGR
CCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCC
SSKIDRATSDSMGMLGTTINALRLQASLEAKGIQTRVQTAIDMKQVAEPYIRRRAIRHIE
CCCCCCCCCCCCCHHHHHHHHEEEEEHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
KGRIVIFAAGTGLPYFSTDTTAALRAVEINADVILAGKRGTDGIYDSDPNKNKNAIKYDK
CCCEEEEECCCCCCEECCCHHHEEEEEEECCCEEEECCCCCCCCCCCCCCCCCCCEEECC
LTYIDILNKGLGIMDATATSLCMENNMGLVVFGIDDPKNIIRVSHGENIGTIVEGDKNE
CCEEEHHHCCCCEEHHHHHHHHEECCCEEEEEECCCCCCEEEEECCCCCCEEECCCCCC
>Mature Secondary Structure 
SLKYKRVLLKLSGEALSGDQGHGLDDDIIESICDAIKVVHDEGLEIAIVVGGGNFWRGR
CCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCC
SSKIDRATSDSMGMLGTTINALRLQASLEAKGIQTRVQTAIDMKQVAEPYIRRRAIRHIE
CCCCCCCCCCCCCHHHHHHHHEEEEEHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
KGRIVIFAAGTGLPYFSTDTTAALRAVEINADVILAGKRGTDGIYDSDPNKNKNAIKYDK
CCCEEEEECCCCCCEECCCHHHEEEEEEECCCEEEECCCCCCCCCCCCCCCCCCCEEECC
LTYIDILNKGLGIMDATATSLCMENNMGLVVFGIDDPKNIIRVSHGENIGTIVEGDKNE
CCEEEHHHCCCCEEHHHHHHHHEECCCEEEEEECCCCCCEEEEECCCCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA